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Research ArticleArticle

Statistical Methods for Analysis of Time-Dependent Inhibition of Cytochrome P450 Enzymes

Phillip Yates, Heather Eng, Li Di and R. Scott Obach
Drug Metabolism and Disposition December 2012, 40 (12) 2289-2296; DOI: https://doi.org/10.1124/dmd.112.047233

Article Information

vol. 40 no. 12 2289-2296
DOI 
https://doi.org/10.1124/dmd.112.047233
PubMed 
22942318
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 13, 2012
  • Accepted August 31, 2012
  • Published online November 14, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Phillip Yates,
  2. Heather Eng,
  3. Li Di, and
  4. R. Scott Obach
  1. PharmaTherapeutics Statistics, Pfizer Inc., Groton, Connecticut (P.Y.); and Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Groton, Connecticut (H.E., L.D., R.S.O.)
  1. Address correspondence to:
    Phillip Yates, PharmaTherapeutics Statistics, Pfizer Inc., Groton, CT 06340. E-mail: pyatesgene{at}gmail.com
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STATISTICAL ANALYSIS OF TIME-DEPENDENT INHIBITION DATA

Phillip Yates, Heather Eng, Li Di and R. Scott Obach
Drug Metabolism and Disposition December 1, 2012, 40 (12) 2289-2296; DOI: https://doi.org/10.1124/dmd.112.047233
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