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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

February 01, 2012; Volume 40,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Albaugh, Daniel

    1. You have access
      Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861
  2. Alvarez, Hamsell M.

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  3. Ambudkar, Suresh V.

    1. You have access
      Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721
  4. Asahi, Satoru

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

B

  1. Badenhorst, Christoffel P. S.

    1. You have access
      Enzymatic Characterization and Elucidation of the Catalytic Mechanism of a Recombinant Bovine Glycine N-Acyltransferase
      Christoffel P. S. Badenhorst, Maritza Jooste and Alberdina A. van Dijk
      Drug Metabolism and Disposition February 2012, 40 (2) 346-352; DOI: https://doi.org/10.1124/dmd.111.041657
  2. Barber, Stuart

    1. You have access
      Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665
  3. Beijnen, Jos H.

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  4. Bi, Yi-an

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  5. Boado, Ruben J.

    1. You have access
      Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903

C

  1. Corcoran, Mary

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

D

  1. Dammanahalli, Jagadeesha K.

    1. You have access
      Oxidative Modification of Rat Sulfotransferase 1A1 Activity in Hepatic Tissue Slices Correlates with Effects on the Purified Enzyme
      Jagadeesha K. Dammanahalli and Michael W. Duffel
      Drug Metabolism and Disposition February 2012, 40 (2) 298-303; DOI: https://doi.org/10.1124/dmd.111.042044
  2. Dennis, Kerry

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  3. Desai, Pankaj B.

    1. You have access
      Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388
  4. Dew, Tristan P.

    1. You have access
      Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665
  5. Doll, Walter J.

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  6. Dubbelman, Anne-Charlotte

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  7. Duffel, Michael W.

    1. You have access
      Oxidative Modification of Rat Sulfotransferase 1A1 Activity in Hepatic Tissue Slices Correlates with Effects on the Purified Enzyme
      Jagadeesha K. Dammanahalli and Michael W. Duffel
      Drug Metabolism and Disposition February 2012, 40 (2) 298-303; DOI: https://doi.org/10.1124/dmd.111.042044

E

  1. El-Kattan, Ayman F.

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  2. Ermer, James C.

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  3. Esatbeyoglu, Tuba

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  4. Escandón, Enrique

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

F

  1. Farrell, Tracy L.

    1. You have access
      Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665
  2. Fenner, Katherine S.

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  3. Fisher, Michael B.

    1. You have access
      Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861
  4. Fujimori, Izumi

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  5. Fukami, Tatsuki

    1. You have access
      Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150
  6. Fullenwider, Cody L.

    1. You have access
      Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

G

  1. Gao, Cheng-Lu

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  2. Gu, Yuan

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  3. Guo, Yingying

    1. You have access
      Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

H

  1. Haffey, Mary B.

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  2. Hashimoto, Tadashi

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614
  3. Hines, Ronald N.

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  4. Homann, Thomas

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  5. Horie, Toru

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  6. Horiguchi, Aya

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  7. Hsieh, SuChun

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  8. Hu, Ming

    1. You have access
      UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467
  9. Hui, Eric Ka-Wai

    1. You have access
      Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903
  10. Huitema, Alwin D. R.

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  11. Hutzler, J. Matthew

    1. You have access
      Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

I

  1. Ibbotson, Sally H.

    1. You have access
      Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085
  2. Ikeda, Toshihiko

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  3. Iseki, Ken

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  4. Ishizuka, Tomoko

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  5. Iwatsubo, Takafumi

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614
  6. Izumi, Takashi

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

J

  1. James, Margaret O.

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  2. Jansen, Robert S.

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  3. Jiang, Wen

    1. You have access
      UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467
  4. Jooste, Maritza

    1. You have access
      Enzymatic Characterization and Elucidation of the Catalytic Mechanism of a Recombinant Bovine Glycine N-Acyltransferase
      Christoffel P. S. Badenhorst, Maritza Jooste and Alberdina A. van Dijk
      Drug Metabolism and Disposition February 2012, 40 (2) 346-352; DOI: https://doi.org/10.1124/dmd.111.041657

K

  1. Kapoor, Khyati

    1. You have access
      Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721
  2. Kato, Yukiko

    1. You have access
      Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150
  3. Kawaguchi, Naohiro

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105
  4. Kimoto, Emi

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  5. Kitamura, Shigeyuki

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  6. Kiyota, Yutaka

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105
  7. Koetz, Barbara

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  8. Kondo, Takahiro

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105
  9. Kotake, Yaichiro

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  10. Kouanda, Abdul

    1. You have access
      Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721
  11. Kulkarni, Supriya R.

    1. You have access
      UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925
  12. Kulling, Sabine E.

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  13. Kurihara, Atsushi

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

L

  1. Lai, Yurong

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  2. Langaee, Taimour

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  3. Lentz, Kimberley A.

    1. You have access
      Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848
  4. Li, Liya

    1. You have access
      UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925
  5. Li, Wenjun

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  6. Linder, Collette

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  7. Lopez-Anaya, Arturo

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  8. Lu, Jeff Zhiqiang

    1. You have access
      Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903
  9. Lymboura, Margarita

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

M

  1. Ma, Bing-Liang

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  2. Ma, Huiping

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  3. Ma, Yue-Ming

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  4. Marian, Melinda

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  5. Martin, Patrick

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  6. McNeilly, Alison D.

    1. You have access
      Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085
  7. Mergui-Roelvink, Marja

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  8. Miyashita, Aiji

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614
  9. Morgan, Daniel G.

    1. You have access
      Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848
  10. Mugundu, Ganesh M.

    1. You have access
      Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

N

  1. Nakahara, Kaori

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  2. Nakajima, Miki

    1. You have access
      Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150
  3. Nishida, Atsuko

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  4. Nishihara, Mitsuhiro

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

O

  1. Oda, Shingo

    1. You have access
      Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150
  2. Ohshita, Hiroki

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  3. Ohta, Shigeru

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  4. Orcutt, Tami L.

    1. You have access
      Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848

P

  1. Page, Richard C.

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  2. Pang, Yinuo

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  3. Pardridge, William M.

    1. You have access
      Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903
  4. Poquet, Laure

    1. You have access
      Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665

Q

  1. Qiu, Fu-Rong

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

R

  1. Rawel, Harshadrai M.

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  2. Reyderman, Larisa

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  3. Rosing, Hilde

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

S

  1. Sakurai, Hidetaka

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  2. Sallans, Larry

    1. You have access
      Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388
  3. Sandefer, Erik P.

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691
  4. Sanoh, Seigo

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  5. Schellens, Jan H. M.

    1. You have access
      Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762
  6. Schmenk, Jennifer

    1. You have access
      Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861
  7. Schwartz, Candice

    1. You have access
      Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721
  8. Shaughnessy, Elizabeth A.

    1. You have access
      Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388
  9. Shinsky-Bjorde, Natasha

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  10. Shiraga, Toshifumi

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614
  11. Shukla, Suneet

    1. You have access
      Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721
  12. Simpson, Pippa

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  13. Sinz, Michael W.

    1. You have access
      Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848
  14. Slitt, Angela L.

    1. You have access
      UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925
  15. Smith, Gillian

    1. You have access
      Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085
  16. So, On-Yee

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  17. Song, Yaoli

    1. You have access
      Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531
  18. Stacpoole, Peter W.

    1. You have access
      Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
  19. Sudo, Miyako

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105
  20. Sugihara, Kazumi

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  21. Suzuki, Katsuhiro

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614
  22. Suzuki, Kenta

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

T

  1. Takahashi, Junzo

    1. You have access
      An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105
  2. Tateno, Chise

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  3. Tayama, Yoshitaka

    1. You have access
      Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923
  4. Trespidi, Laura

    1. You have access
      Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

U

  1. Usui, Takashi

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

V

  1. van Dijk, Alberdina A.

    1. You have access
      Enzymatic Characterization and Elucidation of the Catalytic Mechanism of a Recombinant Bovine Glycine N-Acyltransferase
      Christoffel P. S. Badenhorst, Maritza Jooste and Alberdina A. van Dijk
      Drug Metabolism and Disposition February 2012, 40 (2) 346-352; DOI: https://doi.org/10.1124/dmd.111.041657

W

  1. Walsky, Robert

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  2. Wang, Chang-Hong

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  3. Wang, Xin-Hong

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  4. Weinert, Christoph H.

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  5. Whalen, Kevin M.

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  6. Whiterock, Valerie J.

    1. You have access
      Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848
  7. Wiese, Stefanie

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  8. Williamson, Gary

    1. You have access
      Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665
  9. Winterhalter, Peter

    1. You have access
      Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871
  10. Wolf, C. Roland

    1. You have access
      Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085
  11. Woods, Julie A.

    1. You have access
      Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085
  12. Wu, Baojian

    1. You have access
      UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467
  13. Wu, Jia-Sheng

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

X

  1. Xiao, Yongling

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  2. Xu, Beibei

    1. You have access
      UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467
  3. Xu, Jialin

    1. You have access
      UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925

Y

  1. Yajima, Kanako

    1. You have access
      Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614
  2. Yang, Young-Sun

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
    2. You have access
      Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861
  3. Yao, Meng-Kan

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  4. Yokoi, Tsuyoshi

    1. You have access
      Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150
  5. Yoshigae, Yasushi

    1. You have access
      Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475
  6. Yu, Rong

    1. You have access
      UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467

Z

  1. Zhang, Hui

    1. You have access
      Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
  2. Zhong, Jie

    1. You have access
      Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152
  3. Zhou, Qing-Hui

    1. You have access
      Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903
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Drug Metabolism and Disposition: 40 (2)
Drug Metabolism and Disposition
Vol. 40, Issue 2
1 Feb 2012
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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