Advertisement

Index by author

February 01, 2012; Volume 40,Issue 2

A

  1. Albaugh, Daniel

    1. Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

  2. Alvarez, Hamsell M.

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  3. Ambudkar, Suresh V.

    1. Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721

  4. Asahi, Satoru

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

B

  1. Badenhorst, Christoffel P. S.

    1. Enzymatic Characterization and Elucidation of the Catalytic Mechanism of a Recombinant Bovine Glycine N-Acyltransferase
      Christoffel P. S. Badenhorst, Maritza Jooste and Alberdina A. van Dijk
      Drug Metabolism and Disposition February 2012, 40 (2) 346-352; DOI: https://doi.org/10.1124/dmd.111.041657

  2. Barber, Stuart

    1. Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665

  3. Beijnen, Jos H.

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  4. Bi, Yi-an

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  5. Boado, Ruben J.

    1. Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903

C

  1. Corcoran, Mary

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

D

  1. Dammanahalli, Jagadeesha K.

    1. Oxidative Modification of Rat Sulfotransferase 1A1 Activity in Hepatic Tissue Slices Correlates with Effects on the Purified Enzyme
      Jagadeesha K. Dammanahalli and Michael W. Duffel
      Drug Metabolism and Disposition February 2012, 40 (2) 298-303; DOI: https://doi.org/10.1124/dmd.111.042044

  2. Dennis, Kerry

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  3. Desai, Pankaj B.

    1. Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

  4. Dew, Tristan P.

    1. Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665

  5. Doll, Walter J.

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  6. Dubbelman, Anne-Charlotte

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  7. Duffel, Michael W.

    1. Oxidative Modification of Rat Sulfotransferase 1A1 Activity in Hepatic Tissue Slices Correlates with Effects on the Purified Enzyme
      Jagadeesha K. Dammanahalli and Michael W. Duffel
      Drug Metabolism and Disposition February 2012, 40 (2) 298-303; DOI: https://doi.org/10.1124/dmd.111.042044

E

  1. El-Kattan, Ayman F.

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  2. Ermer, James C.

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  3. Esatbeyoglu, Tuba

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  4. Escandón, Enrique

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

F

  1. Farrell, Tracy L.

    1. Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665

  2. Fenner, Katherine S.

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  3. Fisher, Michael B.

    1. Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

  4. Fujimori, Izumi

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  5. Fukami, Tatsuki

    1. Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150

  6. Fullenwider, Cody L.

    1. Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

G

  1. Gao, Cheng-Lu

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  2. Gu, Yuan

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  3. Guo, Yingying

    1. Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

H

  1. Haffey, Mary B.

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  2. Hashimoto, Tadashi

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

  3. Hines, Ronald N.

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  4. Homann, Thomas

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  5. Horie, Toru

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  6. Horiguchi, Aya

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  7. Hsieh, SuChun

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  8. Hu, Ming

    1. UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467

  9. Hui, Eric Ka-Wai

    1. Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903

  10. Huitema, Alwin D. R.

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  11. Hutzler, J. Matthew

    1. Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

I

  1. Ibbotson, Sally H.

    1. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085

  2. Ikeda, Toshihiko

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  3. Iseki, Ken

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  4. Ishizuka, Tomoko

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  5. Iwatsubo, Takafumi

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

  6. Izumi, Takashi

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

J

  1. James, Margaret O.

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  2. Jansen, Robert S.

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  3. Jiang, Wen

    1. UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467

  4. Jooste, Maritza

    1. Enzymatic Characterization and Elucidation of the Catalytic Mechanism of a Recombinant Bovine Glycine N-Acyltransferase
      Christoffel P. S. Badenhorst, Maritza Jooste and Alberdina A. van Dijk
      Drug Metabolism and Disposition February 2012, 40 (2) 346-352; DOI: https://doi.org/10.1124/dmd.111.041657

K

  1. Kapoor, Khyati

    1. Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721

  2. Kato, Yukiko

    1. Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150

  3. Kawaguchi, Naohiro

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

  4. Kimoto, Emi

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  5. Kitamura, Shigeyuki

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  6. Kiyota, Yutaka

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

  7. Koetz, Barbara

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  8. Kondo, Takahiro

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

  9. Kotake, Yaichiro

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  10. Kouanda, Abdul

    1. Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721

  11. Kulkarni, Supriya R.

    1. UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925

  12. Kulling, Sabine E.

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  13. Kurihara, Atsushi

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

L

  1. Lai, Yurong

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  2. Langaee, Taimour

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  3. Lentz, Kimberley A.

    1. Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848

  4. Li, Liya

    1. UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925

  5. Li, Wenjun

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  6. Linder, Collette

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  7. Lopez-Anaya, Arturo

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  8. Lu, Jeff Zhiqiang

    1. Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903

  9. Lymboura, Margarita

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

M

  1. Ma, Bing-Liang

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  2. Ma, Huiping

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  3. Ma, Yue-Ming

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  4. Marian, Melinda

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  5. Martin, Patrick

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  6. McNeilly, Alison D.

    1. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085

  7. Mergui-Roelvink, Marja

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  8. Miyashita, Aiji

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

  9. Morgan, Daniel G.

    1. Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848

  10. Mugundu, Ganesh M.

    1. Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

N

  1. Nakahara, Kaori

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  2. Nakajima, Miki

    1. Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150

  3. Nishida, Atsuko

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  4. Nishihara, Mitsuhiro

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

O

  1. Oda, Shingo

    1. Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150

  2. Ohshita, Hiroki

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  3. Ohta, Shigeru

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  4. Orcutt, Tami L.

    1. Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848

P

  1. Page, Richard C.

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  2. Pang, Yinuo

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  3. Pardridge, William M.

    1. Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903

  4. Poquet, Laure

    1. Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665

Q

  1. Qiu, Fu-Rong

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

R

  1. Rawel, Harshadrai M.

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  2. Reyderman, Larisa

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  3. Rosing, Hilde

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

S

  1. Sakurai, Hidetaka

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  2. Sallans, Larry

    1. Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

  3. Sandefer, Erik P.

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

  4. Sanoh, Seigo

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  5. Schellens, Jan H. M.

    1. Mass Balance Study of [14C]Eribulin in Patients with Advanced Solid Tumors
      Anne-Charlotte Dubbelman, Hilde Rosing, Robert S. Jansen, Marja Mergui-Roelvink, Alwin D. R. Huitema, Barbara Koetz, Margarita Lymboura, Larisa Reyderman, Arturo Lopez-Anaya, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition February 2012, 40 (2) 313-321; DOI: https://doi.org/10.1124/dmd.111.042762

  6. Schmenk, Jennifer

    1. Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

  7. Schwartz, Candice

    1. Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721

  8. Shaughnessy, Elizabeth A.

    1. Assessment of the Impact of CYP3A Polymorphisms on the Formation of α-Hydroxytamoxifen and N-Desmethyltamoxifen in Human Liver Microsomes
      Ganesh M. Mugundu, Larry Sallans, Yingying Guo, Elizabeth A. Shaughnessy and Pankaj B. Desai
      Drug Metabolism and Disposition February 2012, 40 (2) 389-396; DOI: https://doi.org/10.1124/dmd.111.039388

  9. Shinsky-Bjorde, Natasha

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  10. Shiraga, Toshifumi

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

  11. Shukla, Suneet

    1. Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
      Suneet Shukla, Candice Schwartz, Khyati Kapoor, Abdul Kouanda and Suresh V. Ambudkar
      Drug Metabolism and Disposition February 2012, 40 (2) 304-312; DOI: https://doi.org/10.1124/dmd.111.042721

  12. Simpson, Pippa

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  13. Sinz, Michael W.

    1. Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848

  14. Slitt, Angela L.

    1. UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925

  15. Smith, Gillian

    1. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085

  16. So, On-Yee

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  17. Song, Yaoli

    1. Effects of PEGylation and Immune Complex Formation on the Pharmacokinetics and Biodistribution of Recombinant Interleukin 10 in Mice
      Hamsell M. Alvarez, On-Yee So, SuChun Hsieh, Natasha Shinsky-Bjorde, Huiping Ma, Yaoli Song, Yinuo Pang, Melinda Marian and Enrique Escandón
      Drug Metabolism and Disposition February 2012, 40 (2) 360-373; DOI: https://doi.org/10.1124/dmd.111.042531

  18. Stacpoole, Peter W.

    1. Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate
      Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
      Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

  19. Sudo, Miyako

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

  20. Sugihara, Kazumi

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  21. Suzuki, Katsuhiro

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

  22. Suzuki, Kenta

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

T

  1. Takahashi, Junzo

    1. An Unusual Metabolic Pathway of Sipoglitazar, a Novel Antidiabetic Agent: Cytochrome P450-Catalyzed Oxidation of Sipoglitazar Acyl Glucuronide
      Mitsuhiro Nishihara, Miyako Sudo, Naohiro Kawaguchi, Junzo Takahashi, Yutaka Kiyota, Takahiro Kondo and Satoru Asahi
      Drug Metabolism and Disposition February 2012, 40 (2) 249-258; DOI: https://doi.org/10.1124/dmd.111.040105

  2. Tateno, Chise

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  3. Tayama, Yoshitaka

    1. Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver
      Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition February 2012, 40 (2) 322-328; DOI: https://doi.org/10.1124/dmd.111.040923

  4. Trespidi, Laura

    1. Pharmacokinetics of Lisdexamfetamine Dimesylate after Targeted Gastrointestinal Release or Oral Administration in Healthy Adults
      James C. Ermer, Mary B. Haffey, Walter J. Doll, Patrick Martin, Erik P. Sandefer, Kerry Dennis, Mary Corcoran, Laura Trespidi and Richard C. Page
      Drug Metabolism and Disposition February 2012, 40 (2) 290-297; DOI: https://doi.org/10.1124/dmd.111.040691

U

  1. Usui, Takashi

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

V

  1. van Dijk, Alberdina A.

    1. Enzymatic Characterization and Elucidation of the Catalytic Mechanism of a Recombinant Bovine Glycine N-Acyltransferase
      Christoffel P. S. Badenhorst, Maritza Jooste and Alberdina A. van Dijk
      Drug Metabolism and Disposition February 2012, 40 (2) 346-352; DOI: https://doi.org/10.1124/dmd.111.041657

W

  1. Walsky, Robert

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  2. Wang, Chang-Hong

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  3. Wang, Xin-Hong

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  4. Weinert, Christoph H.

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  5. Whalen, Kevin M.

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  6. Whiterock, Valerie J.

    1. Phenacetin Pharmacokinetics in CYP1A2-Deficient Beagle Dogs
      Valerie J. Whiterock, Daniel G. Morgan, Kimberley A. Lentz, Tami L. Orcutt and Michael W. Sinz
      Drug Metabolism and Disposition February 2012, 40 (2) 228-231; DOI: https://doi.org/10.1124/dmd.111.041848

  7. Wiese, Stefanie

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  8. Williamson, Gary

    1. Predicting Phenolic Acid Absorption in Caco-2 Cells: A Theoretical Permeability Model and Mechanistic Study
      Tracy L. Farrell, Laure Poquet, Tristan P. Dew, Stuart Barber and Gary Williamson
      Drug Metabolism and Disposition February 2012, 40 (2) 397-406; DOI: https://doi.org/10.1124/dmd.111.041665

  9. Winterhalter, Peter

    1. Methylation of Catechins and Procyanidins by Rat and Human Catechol-O-Methyltransferase: Metabolite Profiling and Molecular Modeling Studies
      Christoph H. Weinert, Stefanie Wiese, Harshadrai M. Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann and Sabine E. Kulling
      Drug Metabolism and Disposition February 2012, 40 (2) 353-359; DOI: https://doi.org/10.1124/dmd.111.041871

  10. Wolf, C. Roland

    1. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085

  11. Woods, Julie A.

    1. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1
      Alison D. McNeilly, Julie A. Woods, Sally H. Ibbotson, C. Roland Wolf and Gillian Smith
      Drug Metabolism and Disposition February 2012, 40 (2) 283-289; DOI: https://doi.org/10.1124/dmd.111.042085

  12. Wu, Baojian

    1. UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467

  13. Wu, Jia-Sheng

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

X

  1. Xiao, Yongling

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  2. Xu, Beibei

    1. UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467

  3. Xu, Jialin

    1. UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis
      Jialin Xu, Supriya R. Kulkarni, Liya Li and Angela L. Slitt
      Drug Metabolism and Disposition February 2012, 40 (2) 259-266; DOI: https://doi.org/10.1124/dmd.111.039925

Y

  1. Yajima, Kanako

    1. Identification of UDP-Glucuronosyltransferases Responsible for the Glucuronidation of Darexaban, an Oral Factor Xa Inhibitor, in Human Liver and Intestine
      Toshifumi Shiraga, Kanako Yajima, Kenta Suzuki, Katsuhiro Suzuki, Tadashi Hashimoto, Takafumi Iwatsubo, Aiji Miyashita and Takashi Usui
      Drug Metabolism and Disposition February 2012, 40 (2) 276-282; DOI: https://doi.org/10.1124/dmd.111.042614

  2. Yang, Young-Sun

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297
    2. Characterization of Aldehyde Oxidase Enzyme Activity in Cryopreserved Human Hepatocytes
      J. Matthew Hutzler, Young-Sun Yang, Daniel Albaugh, Cody L. Fullenwider, Jennifer Schmenk and Michael B. Fisher
      Drug Metabolism and Disposition February 2012, 40 (2) 267-275; DOI: https://doi.org/10.1124/dmd.111.042861

  3. Yao, Meng-Kan

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  4. Yokoi, Tsuyoshi

    1. Human UDP-Glucuronosyltransferase Isoforms Involved in Haloperidol Glucuronidation and Quantitative Estimation of Their Contribution
      Yukiko Kato, Miki Nakajima, Shingo Oda, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition February 2012, 40 (2) 240-248; DOI: https://doi.org/10.1124/dmd.111.042150

  5. Yoshigae, Yasushi

    1. Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism
      Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda and Takashi Izumi
      Drug Metabolism and Disposition February 2012, 40 (2) 374-380; DOI: https://doi.org/10.1124/dmd.111.041475

  6. Yu, Rong

    1. UDP-Glucuronosyltransferase (UGT) 1A9-Overexpressing HeLa Cells Is an Appropriate Tool to Delineate the Kinetic Interplay between Breast Cancer Resistance Protein (BRCP) and UGT and to Rapidly Identify the Glucuronide Substrates of BCRP
      Wen Jiang, Beibei Xu, Baojian Wu, Rong Yu and Ming Hu
      Drug Metabolism and Disposition February 2012, 40 (2) 336-345; DOI: https://doi.org/10.1124/dmd.111.041467

Z

  1. Zhang, Hui

    1. Differential Modulation of Cytochrome P450 Activity and the Effect of 1-Aminobenzotriazole on Hepatic Transport in Sandwich-Cultured Human Hepatocytes
      Emi Kimoto, Robert Walsky, Hui Zhang, Yi-an Bi, Kevin M. Whalen, Young-Sun Yang, Collette Linder, Yongling Xiao, Ken Iseki, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition February 2012, 40 (2) 407-411; DOI: https://doi.org/10.1124/dmd.111.039297

  2. Zhong, Jie

    1. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-Pretreated Rats Attributable to Enhanced Intestinal Absorption
      Bing-Liang Ma, Meng-Kan Yao, Jie Zhong, Yue-Ming Ma, Cheng-Lu Gao, Jia-Sheng Wu, Fu-Rong Qiu, Chang-Hong Wang and Xin-Hong Wang
      Drug Metabolism and Disposition February 2012, 40 (2) 381-388; DOI: https://doi.org/10.1124/dmd.111.041152

  3. Zhou, Qing-Hui

    1. Brain-Penetrating IgG-Iduronate 2-Sulfatase Fusion Protein for the Mouse
      Qing-Hui Zhou, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui and William M. Pardridge
      Drug Metabolism and Disposition February 2012, 40 (2) 329-335; DOI: https://doi.org/10.1124/dmd.111.042903
Back to top

In this issue

Advertisement