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Research ArticleArticle

Prenatal and Postnatal Expression of Glutathione Transferase ζ 1 in Human Liver and the Roles of Haplotype and Subject Age in Determining Activity with Dichloroacetate

Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
Drug Metabolism and Disposition February 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
Wenjun Li
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Yuan Gu
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Margaret O. James
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Ronald N. Hines
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Pippa Simpson
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Taimour Langaee
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Peter W. Stacpoole
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Article Information

vol. 40 no. 2 232-239
DOI 
https://doi.org/10.1124/dmd.111.041533
PubMed 
22028318

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 5, 2011
  • Accepted October 25, 2011
  • Published online January 18, 2012.

Article Versions

  • Earlier version (October 25, 2011 - 09:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Wenjun Li,
  2. Yuan Gu,
  3. Margaret O. James,
  4. Ronald N. Hines,
  5. Pippa Simpson,
  6. Taimour Langaee and
  7. Peter W. Stacpoole
  1. Departments of Medicinal Chemistry (W.L., Y.G., M.O.J.) and Pharmacotherapy and Translational Research (T.L.) and Center for Pharmacogenomics (T.L.), College of Pharmacy, and Departments of Medicine and Biochemistry and Molecular Biology (P.W.S.), College of Medicine, University of Florida, Gainesville, Florida; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin (R.N.H., P.S.); and Children's Research Institute, Children's Hospital and Health Systems, Milwaukee, Wisconsin (R.N.H.)
  1. Address correspondence to:
    Dr. Margaret O. James, Department of Medicinal Chemistry, Health Science Center P6-20, University of Florida, P.O. Box 100485, Gainesville, FL 32610-0485. E-mail: mojames{at}ufl.edu
  1. Part of this work was previously presented as follows: James MO, Hines RN, Gu Y, Li W, Langaee T, and Stacpoole PW (2010) Ontogeny of glutathione transferase Z1 expression and activity in human liver cytosol. Ninth International Meeting of the International Society for the Study of Xenobiotics; 2010 Sept 4–8; Istanbul, Turkey. International Society for the Study of Xenobiotics, Washington, DC.

  1. W.L. and Y.G. contributed equally to this work.

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Drug Metabolism and Disposition: 40 (2)
Drug Metabolism and Disposition
Vol. 40, Issue 2
1 Feb 2012
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Research ArticleArticle

GSTZ1 DEVELOPMENT IN HUMAN LIVERS

Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
Drug Metabolism and Disposition February 1, 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533

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Research ArticleArticle

GSTZ1 DEVELOPMENT IN HUMAN LIVERS

Wenjun Li, Yuan Gu, Margaret O. James, Ronald N. Hines, Pippa Simpson, Taimour Langaee and Peter W. Stacpoole
Drug Metabolism and Disposition February 1, 2012, 40 (2) 232-239; DOI: https://doi.org/10.1124/dmd.111.041533
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