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Evaluation of Hepatic Glutathione Transferase Mu 1 and Theta 1 Activities in Humans and Mice Using Genotype Information

Shingo Arakawa, Kazunori Fujimoto, Ayako Kato, Seiko Endo, Aiko Fukahori, Akira Shinagawa, Thomas Fischer, Juergen Mueller and Wataru Takasaki
Drug Metabolism and Disposition March 2012, 40 (3) 497-503; DOI: https://doi.org/10.1124/dmd.111.042911

Article Information

vol. 40 no. 3 497-503
DOI 
https://doi.org/10.1124/dmd.111.042911
PubMed 
22170331
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 22, 2011
  • Accepted December 14, 2011
  • Published online February 15, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Shingo Arakawa,
  2. Kazunori Fujimoto,
  3. Ayako Kato,
  4. Seiko Endo,
  5. Aiko Fukahori,
  6. Akira Shinagawa,
  7. Thomas Fischer,
  8. Juergen Mueller and
  9. Wataru Takasaki
  1. Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., Shizuoka, Japan (S.A., K.F.); Translational Medicine and Clinical Pharmacology Department, Daiichi Sankyo Co., Ltd., Shinagawa-ku, Tokyo, Japan (A.K., S.E., A.F., A.S.); Metabolism Department, Daiichi Sankyo Europe GmbH, Martinsried, Germany (T.F., J.M.); and Daiichi Sankyo Inc., Edison, New Jersey (W.T.)
  1. Address correspondence to:
    Shingo Arakawa, Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 717 Horikoshi, Fukuroi, Shizuoka 437-0065, Japan. E-mail: arakawa.shingo.z6{at}daiichisankyo.co.jp
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GST-NULL GENOTYPES AND HEPATIC ACTIVITIES IN HUMANS AND MICE

Shingo Arakawa, Kazunori Fujimoto, Ayako Kato, Seiko Endo, Aiko Fukahori, Akira Shinagawa, Thomas Fischer, Juergen Mueller and Wataru Takasaki
Drug Metabolism and Disposition March 1, 2012, 40 (3) 497-503; DOI: https://doi.org/10.1124/dmd.111.042911
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