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CYP3A5 Genotype-Phenotype Analysis in the Human Kidney Reveals a Strong Site-Specific Expression of CYP3A5 in the Proximal Tubule in Carriers of the CYP3A5*1 Allele

Juliane Bolbrinker, Stefanie Seeberg, Martin Schostak, Carsten Kempkensteffen, Hans Baelde, Emile de Heer and Reinhold Kreutz
Drug Metabolism and Disposition April 2012, 40 (4) 639-641; DOI: https://doi.org/10.1124/dmd.111.042648

Article Information

vol. 40 no. 4 639-641
DOI 
https://doi.org/10.1124/dmd.111.042648
PubMed 
22214815
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 5, 2011
  • Accepted January 3, 2012
  • Published online March 15, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Juliane Bolbrinker,
  2. Stefanie Seeberg,
  3. Martin Schostak,
  4. Carsten Kempkensteffen,
  5. Hans Baelde,
  6. Emile de Heer and
  7. Reinhold Kreutz
  1. Institute of Clinical Pharmacology and Toxicology, Charité–Universitätsmedizin Berlin, Berlin, Germany (J.B., S.S., R.K.); Department of Urology, Universitätsklinikum Magdeburg, Magdeburg, Germany (M.S.); Department of Urology, Charité–Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany (C.K.); Department of Pathology, Leiden University Medical Center, ZA Leiden, the Netherlands (H.B., E.H.)
  1. Address correspondence to:
    Dr. Juliane Bolbrinker, Institute of Clinical Pharmacology and Toxicology, Charité – Universitätsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany. E-mail: juliane.bolbrinker{at}charite.de

  1. J.B. and S.S. contributed equally to this work.

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Rapid CommunicationShort Communication

CYP3A5 GENOTYPE-PHENOTYPE CORRELATION IN THE HUMAN KIDNEY

Juliane Bolbrinker, Stefanie Seeberg, Martin Schostak, Carsten Kempkensteffen, Hans Baelde, Emile de Heer and Reinhold Kreutz
Drug Metabolism and Disposition April 1, 2012, 40 (4) 639-641; DOI: https://doi.org/10.1124/dmd.111.042648
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