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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

May 01, 2012; Volume 40,Issue 5
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Adomat, Hans

    1. You have access
      Cytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of Catabolism
      Subrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson Guns
      Drug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
  2. Adreani, Christine

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  3. Aichholz, Reiner

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  4. Akiyama, Yuko

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  5. Alfaro, Joshua F.

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  6. Aoyama, Ron G.

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  7. Atadja, Peter

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620

B

  1. Balogh, Larissa

    1. You have access
      Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry
      Anand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
  2. Barton, Hugh A.

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  3. Bauman, Jonathan N.

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  4. Belvin, Marcia

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  5. Bhoopathy, Siddhartha

    1. You have access
      Models to Predict Unbound Intracellular Drug Concentrations in the Presence of Transporters
      Ken R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. Hidalgo
      Drug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
  6. Bi, Yi-an

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  7. Boggs, Jason

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  8. Bourcier, Karine

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  9. Bowalgaha, Kushari

    1. You have access
      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057

C

  1. Chen, Nancy

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  2. Chen, Shuqing

    1. You have access
      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  3. Choo, Edna F.

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  4. Coughlin, John E.

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  5. Cunningham, Paul

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604

D

  1. Davis, John A.

    1. You have access
      Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers
      Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg Slatter
      Drug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
  2. Deane, Molly R.

    1. You have access
      Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers
      Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg Slatter
      Drug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
  3. Deb, Subrata

    1. You have access
      Cytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of Catabolism
      Subrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson Guns
      Drug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
  4. Délémonté, Thierry

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  5. Deng, Yuzhong

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  6. Deo, Anand K.

    1. You have access
      Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry
      Anand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
  7. Deshmukh, Gauri

    1. You have access
      Use of the Cassette-Dosing Approach to Assess Brain Penetration in Drug Discovery
      Xingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. Hop
      Drug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
  8. Ding, Xiao

    1. You have access
      Use of the Cassette-Dosing Approach to Assess Brain Penetration in Drug Discovery
      Xingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. Hop
      Drug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
  9. Duniec-Dmuchowski, Zofia

    1. You have access
      p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
      Althea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. Reiners
      Drug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549

E

  1. El-Kattan, Ayman

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  2. Elliot, David J.

    1. You have access
      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
  3. Elliott, Althea

    1. You have access
      p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
      Althea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. Reiners
      Drug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
  4. Emery, Maurice G.

    1. You have access
      Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers
      Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg Slatter
      Drug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
  5. Empey, Philip E.

    1. You have access
      Stereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux Analysis
      Lipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616

F

  1. Fauty, Scott

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  2. Fenner, Katherine S.

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  3. Fredenhagen, Andreas

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  4. Freiwald, Sascha

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  5. Fujita, Ken-ichi

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893

G

  1. Galetin, Aleksandra

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  2. Gao, Wei

    1. You have access
      Target-Mediated Pharmacokinetic and Pharmacodynamic Model of Exendin-4 in Rats, Monkeys, and Humans
      Wei Gao and William J. Jusko
      Drug Metabolism and Disposition May 2012, 40 (5) 990-997; DOI: https://doi.org/10.1124/dmd.111.042291
  3. Garattini, Enrico

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  4. Gawronski, Brian E.

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  5. Giddens, Georgina

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  6. Gong, Yan

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  7. Goosen, Theunis C.

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  8. Green, Carol E.

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  9. Greene, Robert J.

    1. You have access
      Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers
      Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg Slatter
      Drug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
  10. Groff, Michelle

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  11. Guns, Emma S. Tomlinson

    1. You have access
      Cytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of Catabolism
      Subrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson Guns
      Drug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681

H

  1. Hamuro, Lora

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  2. Hartmann, Tobias

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  3. Hidalgo, Ismael J.

    1. You have access
      Models to Predict Unbound Intracellular Drug Concentrations in the Presence of Transporters
      Ken R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. Hidalgo
      Drug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
  4. Hioki, Kazuhito

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  5. Hoeflich, Klaus P.

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  6. Hollenberg, Paul F.

    1. You have access
      Identification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice Effect
      Hsia-lien Lin, Cesar Kenaan and Paul F. Hollenberg
      Drug Metabolism and Disposition May 2012, 40 (5) 998-1006; DOI: https://doi.org/10.1124/dmd.112.044560
  7. Hong, Junyan

    1. You have access
      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  8. Hong, Xuening

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  9. Hong, Yanjun

    1. You have access
      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  10. Hop, Cornelis E. C. A.

    1. You have access
      Use of the Cassette-Dosing Approach to Assess Brain Penetration in Drug Discovery
      Xingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. Hop
      Drug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
  11. Houston, J. Brian

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  12. Hyland, Ruth

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117

I

  1. Iwatsubo, Takafumi

    1. You have access
      Conclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human Liver
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208
  2. Iyer, Radhakrishnan P.

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446

J

  1. Jiang, Ying

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  2. Johnson, Chris V.

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  3. Johnson, Julie A.

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  4. Johnston, Stuart H.

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  5. Joiakim, Aby

    1. You have access
      p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
      Althea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. Reiners
      Drug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
  6. Jones, Hannah M.

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  7. Jones, J. P.

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  8. Jones, Jeffrey P.

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  9. Jusko, William J.

    1. You have access
      Target-Mediated Pharmacokinetic and Pharmacodynamic Model of Exendin-4 in Rats, Monkeys, and Humans
      Wei Gao and William J. Jusko
      Drug Metabolism and Disposition May 2012, 40 (5) 990-997; DOI: https://doi.org/10.1124/dmd.111.042291

K

  1. Kaspera, Rüdiger

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  2. Kassees, Robert

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  3. Katayama, Jonathan

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  4. Kawai, Keiichi

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  5. Kempshall, Sarah

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  6. Kenaan, Cesar

    1. You have access
      Identification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice Effect
      Hsia-lien Lin, Cesar Kenaan and Paul F. Hollenberg
      Drug Metabolism and Disposition May 2012, 40 (5) 998-1006; DOI: https://doi.org/10.1124/dmd.112.044560
  7. Khalifa, Sherief I.

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  8. Kielbasa, W.

    1. You have access
      Exploratory Translational Modeling Approach in Drug Development to Predict Human Brain Pharmacokinetics and Pharmacologically Relevant Clinical Doses
      W. Kielbasa and R. E. Stratford
      Drug Metabolism and Disposition May 2012, 40 (5) 877-883; DOI: https://doi.org/10.1124/dmd.111.043554
  9. Kimoto, Emi

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  10. Kittelmann, Matthias

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  11. Knights, Kathleen M.

    1. You have access
      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
  12. Kobayashi, Masato

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  13. Kocarek, Thomas A.

    1. You have access
      p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
      Althea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. Reiners
      Drug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
  14. Korzekwa, Ken R.

    1. You have access
      Models to Predict Unbound Intracellular Drug Concentrations in the Presence of Transporters
      Ken R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. Hidalgo
      Drug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
  15. Kuepfer, Lars

    1. You have access
      Using Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic Modeling
      Michaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg Lippert
      Drug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
  16. Kuhn, Anton

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  17. Kühnöl, Jürgen

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  18. Kunishima, Munetaka

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893

L

  1. Lai, Yurong

    1. You have access
      Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry
      Anand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
    2. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  2. Langaee, Taimour Y.

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  3. Lapham, Kimberly

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  4. Lee, Caroline A.

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  5. Leggas, Markos

    1. You have access
      Stereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux Analysis
      Lipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
  6. Leimkühler, Silke

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  7. Li, Zhaohui

    1. You have access
      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  8. Liederer, Bianca M.

    1. You have access
      Use of the Cassette-Dosing Approach to Assess Brain Penetration in Drug Discovery
      Xingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. Hop
      Drug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
  9. Lin, Hsia-lien

    1. You have access
      Identification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice Effect
      Hsia-lien Lin, Cesar Kenaan and Paul F. Hollenberg
      Drug Metabolism and Disposition May 2012, 40 (5) 998-1006; DOI: https://doi.org/10.1124/dmd.112.044560
  10. Lippert, Joerg

    1. You have access
      Using Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic Modeling
      Michaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg Lippert
      Drug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
  11. Liu, Liming

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  12. Liu, Ting

    1. You have access
      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  13. Liu, Xingrong

    1. You have access
      Use of the Cassette-Dosing Approach to Assess Brain Penetration in Drug Discovery
      Xingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. Hop
      Drug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
  14. Ludewig, Bernd

    1. You have access
      Using Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic Modeling
      Michaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg Lippert
      Drug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
  15. Ly, Justin

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778

M

  1. Marquis, Judith

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  2. Martini, Jean F.

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  3. Mathieu, Patricia A.

    1. You have access
      p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
      Althea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. Reiners
      Drug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
  4. McNamara, Patrick J.

    1. You have access
      Stereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux Analysis
      Lipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
    2. You have access
      Stereoselective Interaction of Pantoprazole with ABCG2. I. Drug Accumulation in Rat Milk
      Lipeng Wang and Patrick J. McNamara
      Drug Metabolism and Disposition May 2012, 40 (5) 1018-1023; DOI: https://doi.org/10.1124/dmd.111.041608
  5. Merchant, Mark

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  6. Meyer, Michaela

    1. You have access
      Using Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic Modeling
      Michaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg Lippert
      Drug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
  7. Michel, Kimberly

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  8. Miners, John O.

    1. You have access
      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
  9. Mirsalis, Jon C.

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  10. Miyashita, Aiji

    1. You have access
      Conclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human Liver
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208

N

  1. Nagar, Swati

    1. You have access
      Models to Predict Unbound Intracellular Drug Concentrations in the Presence of Transporters
      Ken R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. Hidalgo
      Drug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
  2. Negahban, Andre

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  3. Nishi, Kodai

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  4. Nunes, Christian N.

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604

O

  1. O'Loughlin, Kathleen G.

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  2. Obach, R. Scott

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  3. Oberer, Lukas

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  4. Orr, Christine

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778

P

  1. Padmanabhan, Seetharamaiyer

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  2. Pandey, Mitali

    1. You have access
      Cytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of Catabolism
      Subrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson Guns
      Drug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
  3. Pandey, Rajendra K.

    1. You have access
      Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate
      John E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. Iyer
      Drug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
  4. Plise, Emile

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  5. Prasad, Bhagwat

    1. You have access
      Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry
      Anand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
  6. Prueksaritanont, Thomayant

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604

R

  1. Ramaiya, Atulkumar

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  2. Reiners, John J.

    1. You have access
      p-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell Cycle
      Althea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. Reiners
      Drug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
  3. Robarge, Kirk

    1. You have access
      Preclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy Predictions
      Edna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. Johnston
      Drug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
  4. Rowland, Andrew

    1. You have access
      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
  5. Ryder, Tim F.

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117

S

  1. Sasaki, Yasutsuna

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  2. Sato, Yuichiro

    1. You have access
      Conclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human Liver
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208
  3. Schneckener, Sebastian

    1. You have access
      Using Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic Modeling
      Michaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg Lippert
      Drug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
  4. Shahin, Mohamed Hossam A.

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  5. Shen, Xiaolan

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  6. Shultz, Michael D.

    1. You have access
      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  7. Slatter, J. Greg

    1. You have access
      Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers
      Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg Slatter
      Drug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
  8. Smith, Evan

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  9. Stratford, R. E.

    1. You have access
      Exploratory Translational Modeling Approach in Drug Development to Predict Human Brain Pharmacokinetics and Pharmacologically Relevant Clinical Doses
      W. Kielbasa and R. E. Stratford
      Drug Metabolism and Disposition May 2012, 40 (5) 877-883; DOI: https://doi.org/10.1124/dmd.111.043554
  10. Subramanian, Raju

    1. You have access
      Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers
      Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg Slatter
      Drug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
  11. Sugiyama, Minako

    1. You have access
      N-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19
      Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna Sasaki
      Drug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
  12. Sun, Xiaochun

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255

T

  1. Tassaneeyakul, Wichittra

    1. You have access
      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
  2. Tate, Sonya C.

    1. You have access
      Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data
      Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner
      Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
  3. Terao, Mineko

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  4. Teutloff, Christian

    1. You have access
      The Impact of Single Nucleotide Polymorphisms on Human Aldehyde Oxidase
      Tobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke Leimkühler
      Drug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
  5. Totah, Rheem A.

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  6. Tucker, Jalia

    1. You have access
      Models to Predict Unbound Intracellular Drug Concentrations in the Presence of Transporters
      Ken R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. Hidalgo
      Drug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289

U

  1. Unadkat, Jashvant D.

    1. You have access
      Interindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass Spectrometry
      Anand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. Unadkat
      Drug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
  2. Usui, Takashi

    1. You have access
      Conclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human Liver
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208

W

  1. Walker, Gregory S.

    1. You have access
      Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity
      Caroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. Totah
      Drug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
  2. Walsky, Robert L.

    1. You have access
      Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors
      Robert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. Goosen
      Drug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
  3. Wang, Bo

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  4. Wang, Danxin

    1. You have access
      CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human Livers
      Danxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. Johnson
      Drug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
  5. Wang, Lipeng

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      Stereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux Analysis
      Lipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
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      Stereoselective Interaction of Pantoprazole with ABCG2. I. Drug Accumulation in Rat Milk
      Lipeng Wang and Patrick J. McNamara
      Drug Metabolism and Disposition May 2012, 40 (5) 1018-1023; DOI: https://doi.org/10.1124/dmd.111.041608
  6. Wang, Ping

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      Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)
      Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
      Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
  7. Wang, Weirong

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      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
  8. Wattanachai, Nitsupa

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      Effect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug Clearance
      Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
  9. Weiskircher, Erica A.

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      Models to Predict Unbound Intracellular Drug Concentrations in the Presence of Transporters
      Ken R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. Hidalgo
      Drug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289

Y

  1. Yin, Kuo-chang

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      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604

Z

  1. Zeng, Su

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      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  2. Zheng, Mingyue

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      An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
      Ting Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing Chen
      Drug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
  3. Zou, Yan

    1. You have access
      Lymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and Dogs
      Weirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant Prueksaritanont
      Drug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
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Drug Metabolism and Disposition: 40 (5)
Drug Metabolism and Disposition
Vol. 40, Issue 5
1 May 2012
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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