Index by author
May 01, 2012; Volume 40,Issue 5
A
Adomat, Hans
- You have accessCytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of CatabolismSubrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson GunsDrug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
Adreani, Christine
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Aichholz, Reiner
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Akiyama, Yuko
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Alfaro, Joshua F.
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Aoyama, Ron G.
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Atadja, Peter
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
B
Balogh, Larissa
- You have accessInterindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass SpectrometryAnand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
Barton, Hugh A.
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Bauman, Jonathan N.
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Belvin, Marcia
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Bhoopathy, Siddhartha
- You have accessModels to Predict Unbound Intracellular Drug Concentrations in the Presence of TransportersKen R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. HidalgoDrug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
Bi, Yi-an
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Boggs, Jason
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Bourcier, Karine
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Bowalgaha, Kushari
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
C
Chen, Nancy
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Chen, Shuqing
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Choo, Edna F.
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Coughlin, John E.
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Cunningham, Paul
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
D
Davis, John A.
- You have accessRegiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral CentersRobert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg SlatterDrug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
Deane, Molly R.
- You have accessRegiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral CentersRobert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg SlatterDrug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
Deb, Subrata
- You have accessCytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of CatabolismSubrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson GunsDrug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
Délémonté, Thierry
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Deng, Yuzhong
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Deo, Anand K.
- You have accessInterindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass SpectrometryAnand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
Deshmukh, Gauri
- You have accessUse of the Cassette-Dosing Approach to Assess Brain Penetration in Drug DiscoveryXingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. HopDrug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
Ding, Xiao
- You have accessUse of the Cassette-Dosing Approach to Assess Brain Penetration in Drug DiscoveryXingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. HopDrug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
Duniec-Dmuchowski, Zofia
- You have accessp-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell CycleAlthea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. ReinersDrug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
E
El-Kattan, Ayman
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Elliot, David J.
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
Elliott, Althea
- You have accessp-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell CycleAlthea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. ReinersDrug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
Emery, Maurice G.
- You have accessRegiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral CentersRobert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg SlatterDrug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
Empey, Philip E.
- You have accessStereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux AnalysisLipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamaraDrug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
F
Fauty, Scott
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Fenner, Katherine S.
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Fredenhagen, Andreas
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Freiwald, Sascha
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Fujita, Ken-ichi
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
G
Galetin, Aleksandra
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Gao, Wei
- You have accessTarget-Mediated Pharmacokinetic and Pharmacodynamic Model of Exendin-4 in Rats, Monkeys, and HumansWei Gao and William J. JuskoDrug Metabolism and Disposition May 2012, 40 (5) 990-997; DOI: https://doi.org/10.1124/dmd.111.042291
Garattini, Enrico
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Gawronski, Brian E.
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Giddens, Georgina
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Gong, Yan
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Goosen, Theunis C.
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Green, Carol E.
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Greene, Robert J.
- You have accessRegiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral CentersRobert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg SlatterDrug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
Groff, Michelle
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Guns, Emma S. Tomlinson
- You have accessCytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of CatabolismSubrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson GunsDrug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
H
Hamuro, Lora
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Hartmann, Tobias
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Hidalgo, Ismael J.
- You have accessModels to Predict Unbound Intracellular Drug Concentrations in the Presence of TransportersKen R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. HidalgoDrug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
Hioki, Kazuhito
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Hoeflich, Klaus P.
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Hollenberg, Paul F.
- You have accessIdentification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice EffectHsia-lien Lin, Cesar Kenaan and Paul F. HollenbergDrug Metabolism and Disposition May 2012, 40 (5) 998-1006; DOI: https://doi.org/10.1124/dmd.112.044560
Hong, Junyan
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Hong, Xuening
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Hong, Yanjun
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Hop, Cornelis E. C. A.
- You have accessUse of the Cassette-Dosing Approach to Assess Brain Penetration in Drug DiscoveryXingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. HopDrug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
Houston, J. Brian
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Hyland, Ruth
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
I
Iwatsubo, Takafumi
- You have accessConclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human LiverYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208
Iyer, Radhakrishnan P.
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
J
Jiang, Ying
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Johnson, Chris V.
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Johnson, Julie A.
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Johnston, Stuart H.
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Joiakim, Aby
- You have accessp-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell CycleAlthea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. ReinersDrug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
Jones, Hannah M.
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Jones, J. P.
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Jones, Jeffrey P.
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Jusko, William J.
- You have accessTarget-Mediated Pharmacokinetic and Pharmacodynamic Model of Exendin-4 in Rats, Monkeys, and HumansWei Gao and William J. JuskoDrug Metabolism and Disposition May 2012, 40 (5) 990-997; DOI: https://doi.org/10.1124/dmd.111.042291
K
Kaspera, Rüdiger
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Kassees, Robert
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Katayama, Jonathan
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Kawai, Keiichi
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Kempshall, Sarah
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Kenaan, Cesar
- You have accessIdentification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice EffectHsia-lien Lin, Cesar Kenaan and Paul F. HollenbergDrug Metabolism and Disposition May 2012, 40 (5) 998-1006; DOI: https://doi.org/10.1124/dmd.112.044560
Khalifa, Sherief I.
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Kielbasa, W.
- You have accessExploratory Translational Modeling Approach in Drug Development to Predict Human Brain Pharmacokinetics and Pharmacologically Relevant Clinical DosesW. Kielbasa and R. E. StratfordDrug Metabolism and Disposition May 2012, 40 (5) 877-883; DOI: https://doi.org/10.1124/dmd.111.043554
Kimoto, Emi
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Kittelmann, Matthias
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Knights, Kathleen M.
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
Kobayashi, Masato
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Kocarek, Thomas A.
- You have accessp-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell CycleAlthea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. ReinersDrug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
Korzekwa, Ken R.
- You have accessModels to Predict Unbound Intracellular Drug Concentrations in the Presence of TransportersKen R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. HidalgoDrug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
Kuepfer, Lars
- You have accessUsing Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic ModelingMichaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg LippertDrug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
Kuhn, Anton
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Kühnöl, Jürgen
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Kunishima, Munetaka
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
L
Lai, Yurong
- You have accessInterindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass SpectrometryAnand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Langaee, Taimour Y.
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Lapham, Kimberly
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Lee, Caroline A.
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Leggas, Markos
- You have accessStereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux AnalysisLipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamaraDrug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
Leimkühler, Silke
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Li, Zhaohui
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Liederer, Bianca M.
- You have accessUse of the Cassette-Dosing Approach to Assess Brain Penetration in Drug DiscoveryXingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. HopDrug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
Lin, Hsia-lien
- You have accessIdentification of the Residue in Human CYP3A4 That Is Covalently Modified by Bergamottin and the Reactive Intermediate That Contributes to the Grapefruit Juice EffectHsia-lien Lin, Cesar Kenaan and Paul F. HollenbergDrug Metabolism and Disposition May 2012, 40 (5) 998-1006; DOI: https://doi.org/10.1124/dmd.112.044560
Lippert, Joerg
- You have accessUsing Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic ModelingMichaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg LippertDrug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
Liu, Liming
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Liu, Ting
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Liu, Xingrong
- You have accessUse of the Cassette-Dosing Approach to Assess Brain Penetration in Drug DiscoveryXingrong Liu, Xiao Ding, Gauri Deshmukh, Bianca M. Liederer and Cornelis E. C. A. HopDrug Metabolism and Disposition May 2012, 40 (5) 963-969; DOI: https://doi.org/10.1124/dmd.111.044420
Ludewig, Bernd
- You have accessUsing Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic ModelingMichaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg LippertDrug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
Ly, Justin
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
M
Marquis, Judith
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Martini, Jean F.
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Mathieu, Patricia A.
- You have accessp-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell CycleAlthea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. ReinersDrug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
McNamara, Patrick J.
- You have accessStereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux AnalysisLipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamaraDrug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
- You have accessStereoselective Interaction of Pantoprazole with ABCG2. I. Drug Accumulation in Rat MilkLipeng Wang and Patrick J. McNamaraDrug Metabolism and Disposition May 2012, 40 (5) 1018-1023; DOI: https://doi.org/10.1124/dmd.111.041608
Merchant, Mark
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Meyer, Michaela
- You have accessUsing Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic ModelingMichaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg LippertDrug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
Michel, Kimberly
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Miners, John O.
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
Mirsalis, Jon C.
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Miyashita, Aiji
- You have accessConclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human LiverYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208
N
Nagar, Swati
- You have accessModels to Predict Unbound Intracellular Drug Concentrations in the Presence of TransportersKen R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. HidalgoDrug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
Negahban, Andre
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Nishi, Kodai
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Nunes, Christian N.
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
O
O'Loughlin, Kathleen G.
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Obach, R. Scott
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Oberer, Lukas
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Orr, Christine
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
P
Padmanabhan, Seetharamaiyer
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Pandey, Mitali
- You have accessCytochrome P450 3A-Mediated Microsomal Biotransformation of 1α,25-Dihydroxyvitamin D3 in Mouse and Human Liver: Drug-Related Induction and Inhibition of CatabolismSubrata Deb, Mitali Pandey, Hans Adomat and Emma S. Tomlinson GunsDrug Metabolism and Disposition May 2012, 40 (5) 907-918; DOI: https://doi.org/10.1124/dmd.111.041681
Pandey, Rajendra K.
- You have accessMetabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside PhosphorothioateJohn E. Coughlin, Rajendra K. Pandey, Seetharamaiyer Padmanabhan, Kathleen G. O'Loughlin, Judith Marquis, Carol E. Green, Jon C. Mirsalis and Radhakrishnan P. IyerDrug Metabolism and Disposition May 2012, 40 (5) 970-981; DOI: https://doi.org/10.1124/dmd.111.044446
Plise, Emile
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Prasad, Bhagwat
- You have accessInterindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass SpectrometryAnand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
Prueksaritanont, Thomayant
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
R
Ramaiya, Atulkumar
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Reiners, John J.
- You have accessp-Anilinoaniline Enhancement of Dioxin-Induced CYP1A1 Transcription and Aryl Hydrocarbon Receptor Occupancy of CYP1A1 Promoter: Role of the Cell CycleAlthea Elliott, Aby Joiakim, Patricia A. Mathieu, Zofia Duniec-Dmuchowski, Thomas A. Kocarek and John J. ReinersDrug Metabolism and Disposition May 2012, 40 (5) 1032-1040; DOI: https://doi.org/10.1124/dmd.111.042549
Robarge, Kirk
- You have accessPreclinical Disposition of GDC-0973 and Prospective and Retrospective Analysis of Human Dose and Efficacy PredictionsEdna F. Choo, Marcia Belvin, Jason Boggs, Yuzhong Deng, Klaus P. Hoeflich, Justin Ly, Mark Merchant, Christine Orr, Emile Plise, Kirk Robarge, Jean F. Martini, Robert Kassees, Ron G. Aoyama, Atulkumar Ramaiya and Stuart H. JohnstonDrug Metabolism and Disposition May 2012, 40 (5) 919-927; DOI: https://doi.org/10.1124/dmd.111.043778
Rowland, Andrew
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
Ryder, Tim F.
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
S
Sasaki, Yasutsuna
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Sato, Yuichiro
- You have accessConclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human LiverYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208
Schneckener, Sebastian
- You have accessUsing Expression Data for Quantification of Active Processes in Physiologically Based Pharmacokinetic ModelingMichaela Meyer, Sebastian Schneckener, Bernd Ludewig, Lars Kuepfer and Joerg LippertDrug Metabolism and Disposition May 2012, 40 (5) 892-901; DOI: https://doi.org/10.1124/dmd.111.043174
Shahin, Mohamed Hossam A.
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Shen, Xiaolan
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Shultz, Michael D.
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Slatter, J. Greg
- You have accessRegiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral CentersRobert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg SlatterDrug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
Smith, Evan
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Stratford, R. E.
- You have accessExploratory Translational Modeling Approach in Drug Development to Predict Human Brain Pharmacokinetics and Pharmacologically Relevant Clinical DosesW. Kielbasa and R. E. StratfordDrug Metabolism and Disposition May 2012, 40 (5) 877-883; DOI: https://doi.org/10.1124/dmd.111.043554
Subramanian, Raju
- You have accessRegiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral CentersRobert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery and J. Greg SlatterDrug Metabolism and Disposition May 2012, 40 (5) 928-942; DOI: https://doi.org/10.1124/dmd.111.043166
Sugiyama, Minako
- You have accessN-Isopropyl-p-iodoamphetamine Hydrochloride Is Predominantly Metabolized by CYP2C19Ken-ichi Fujita, Minako Sugiyama, Yuko Akiyama, Kazuhito Hioki, Munetaka Kunishima, Kodai Nishi, Masato Kobayashi, Keiichi Kawai and Yasutsuna SasakiDrug Metabolism and Disposition May 2012, 40 (5) 843-846; DOI: https://doi.org/10.1124/dmd.111.043893
Sun, Xiaochun
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
T
Tassaneeyakul, Wichittra
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
Tate, Sonya C.
- You have accessMechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte DataHannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. FennerDrug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994
Terao, Mineko
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Teutloff, Christian
- You have accessThe Impact of Single Nucleotide Polymorphisms on Human Aldehyde OxidaseTobias Hartmann, Mineko Terao, Enrico Garattini, Christian Teutloff, Joshua F. Alfaro, Jeffrey P. Jones and Silke LeimkühlerDrug Metabolism and Disposition May 2012, 40 (5) 856-864; DOI: https://doi.org/10.1124/dmd.111.043828
Totah, Rheem A.
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Tucker, Jalia
- You have accessModels to Predict Unbound Intracellular Drug Concentrations in the Presence of TransportersKen R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. HidalgoDrug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
U
Unadkat, Jashvant D.
- You have accessInterindividual Variability in Hepatic Expression of the Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2): Quantification by Liquid Chromatography/Tandem Mass SpectrometryAnand K. Deo, Bhagwat Prasad, Larissa Balogh, Yurong Lai and Jashvant D. UnadkatDrug Metabolism and Disposition May 2012, 40 (5) 852-855; DOI: https://doi.org/10.1124/dmd.111.043810
Usui, Takashi
- You have accessConclusive Identification of the Oxybutynin-Hydrolyzing Enzyme in Human LiverYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition May 2012, 40 (5) 902-906; DOI: https://doi.org/10.1124/dmd.111.043208
W
Walker, Gregory S.
- You have accessIdentifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 ActivityCaroline A. Lee, J. P. Jones, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker and Rheem A. TotahDrug Metabolism and Disposition May 2012, 40 (5) 943-951; DOI: https://doi.org/10.1124/dmd.111.043505
Walsky, Robert L.
- You have accessOptimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT InhibitorsRobert L. Walsky, Jonathan N. Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F. Ryder, R. Scott Obach, Ruth Hyland and Theunis C. GoosenDrug Metabolism and Disposition May 2012, 40 (5) 1051-1065; DOI: https://doi.org/10.1124/dmd.111.043117
Wang, Bo
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Wang, Danxin
- You have accessCYP2C9 Promoter Variable Number Tandem Repeat Polymorphism Regulates mRNA Expression in Human LiversDanxin Wang, Xiaochun Sun, Yan Gong, Brian E. Gawronski, Taimour Y. Langaee, Mohamed Hossam A. Shahin, Sherief I. Khalifa and Julie A. JohnsonDrug Metabolism and Disposition May 2012, 40 (5) 884-891; DOI: https://doi.org/10.1124/dmd.111.044255
Wang, Lipeng
- You have accessStereoselective Interaction of Pantoprazole with ABCG2. II. In Vitro Flux AnalysisLipeng Wang, Markos Leggas, Philip E. Empey and Patrick J. McNamaraDrug Metabolism and Disposition May 2012, 40 (5) 1024-1031; DOI: https://doi.org/10.1124/dmd.111.041616
- You have accessStereoselective Interaction of Pantoprazole with ABCG2. I. Drug Accumulation in Rat MilkLipeng Wang and Patrick J. McNamaraDrug Metabolism and Disposition May 2012, 40 (5) 1018-1023; DOI: https://doi.org/10.1124/dmd.111.041608
Wang, Ping
- You have accessBiocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. ShultzDrug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
Wang, Weirong
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Wattanachai, Nitsupa
- You have accessEffect of Albumin on Human Liver Microsomal and Recombinant CYP1A2 Activities: Impact on In Vitro-In Vivo Extrapolation of Drug ClearanceNitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. MinersDrug Metabolism and Disposition May 2012, 40 (5) 982-989; DOI: https://doi.org/10.1124/dmd.111.044057
Weiskircher, Erica A.
- You have accessModels to Predict Unbound Intracellular Drug Concentrations in the Presence of TransportersKen R. Korzekwa, Swati Nagar, Jalia Tucker, Erica A. Weiskircher, Siddhartha Bhoopathy and Ismael J. HidalgoDrug Metabolism and Disposition May 2012, 40 (5) 865-876; DOI: https://doi.org/10.1124/dmd.111.044289
Y
Yin, Kuo-chang
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
Z
Zeng, Su
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Zheng, Mingyue
- You have accessAn Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han PopulationTing Liu, Yanjun Hong, Zhaohui Li, Junyan Hong, Su Zeng, Mingyue Zheng and Shuqing ChenDrug Metabolism and Disposition May 2012, 40 (5) 847-851; DOI: https://doi.org/10.1124/dmd.111.044016
Zou, Yan
- You have accessLymphatic Transport and Catabolism of Therapeutic Proteins after Subcutaneous Administration to Rats and DogsWeirong Wang, Nancy Chen, Xiaolan Shen, Paul Cunningham, Scott Fauty, Kimberly Michel, Bo Wang, Xuening Hong, Christine Adreani, Christian N. Nunes, Chris V. Johnson, Kuo-chang Yin, Michelle Groff, Yan Zou, Liming Liu, Lora Hamuro and Thomayant PrueksaritanontDrug Metabolism and Disposition May 2012, 40 (5) 952-962; DOI: https://doi.org/10.1124/dmd.111.043604
In this issue

Advertisement