Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data

Hannah M. Jones; Hugh A. Barton; Yurong Lai; Yi-an Bi; Emi Kimoto; Sarah Kempshall; Sonya C. Tate; Ayman El-Kattan; J. Brian Houston; Aleksandra Galetin; Katherine S. Fenner

doi:10.1124/dmd.111.042994

Research ArticleArticle

Mechanistic Pharmacokinetic Modeling for the Prediction of Transporter-Mediated Disposition in Humans from Sandwich Culture Human Hepatocyte Data

Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner

Drug Metabolism and Disposition May 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994

Hannah M. Jones

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Hugh A. Barton

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Yurong Lai

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Yi-an Bi

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Emi Kimoto

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Sarah Kempshall

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Sonya C. Tate

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Ayman El-Kattan

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J. Brian Houston

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Aleksandra Galetin

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Katherine S. Fenner

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Drug Metabolism and Disposition

Vol. 40, Issue 5

1 May 2012

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Research ArticleArticle

PREDICTION OF TRANSPORTER-MEDIATED DISPOSITION IN HUMANS

Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner

Drug Metabolism and Disposition May 1, 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994

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Research ArticleArticle

PREDICTION OF TRANSPORTER-MEDIATED DISPOSITION IN HUMANS

Hannah M. Jones, Hugh A. Barton, Yurong Lai, Yi-an Bi, Emi Kimoto, Sarah Kempshall, Sonya C. Tate, Ayman El-Kattan, J. Brian Houston, Aleksandra Galetin and Katherine S. Fenner

Drug Metabolism and Disposition May 1, 2012, 40 (5) 1007-1017; DOI: https://doi.org/10.1124/dmd.111.042994

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