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Biocatalytic Synthesis and Structure Elucidation of Cyclized Metabolites of the Deacetylase Inhibitor Panobinostat (LBH589)

Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
Drug Metabolism and Disposition May 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
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Research ArticleArticle

BIOCATALYTIC SYNTHESIS OF PANOBINOSTAT METABOLITES

Andreas Fredenhagen, Matthias Kittelmann, Lukas Oberer, Anton Kuhn, Jürgen Kühnöl, Thierry Délémonté, Reiner Aichholz, Ping Wang, Peter Atadja and Michael D. Shultz
Drug Metabolism and Disposition May 1, 2012, 40 (5) 1041-1050; DOI: https://doi.org/10.1124/dmd.111.043620
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