Drug Metabolism and Disposition: 40 (6)

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About the cover: Relative proportions of P450 mRNAs at selected ages (days 1, 15, and 45, which represent neonatal, adolescent, and adult ages, respectively). See the article by Cui et al. on page 1226 of this issue.

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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

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