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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

June 01, 2012; Volume 40,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Agarwal, Sagar

    1. You have access
      Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
      Sagar Agarwal, Yasuo Uchida, Rajendar K. Mittapalli, Ramola Sane, Tetsuya Terasaki and William F. Elmquist
      Drug Metabolism and Disposition June 2012, 40 (6) 1164-1169; DOI: https://doi.org/10.1124/dmd.112.044719
  2. Aleksunes, Lauren

    1. You have access
      Transcription Factor-Mediated Regulation of Carboxylesterase Enzymes in Livers of Mice
      Youcai Zhang, Xingguo Cheng, Lauren Aleksunes and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1191-1197; DOI: https://doi.org/10.1124/dmd.111.043877
  3. Aoki, Yasuhiro

    1. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883

B

  1. Babu, Ellappan

    1. You have access
      Electrophysiological Characterization of the Polyspecific Organic Cation Transporter Plasma Membrane Monoamine Transporter
      Shiro Itagaki, Vadivel Ganapathy, Horace T. B. Ho, Mingyan Zhou, Ellappan Babu and Joanne Wang
      Drug Metabolism and Disposition June 2012, 40 (6) 1138-1143; DOI: https://doi.org/10.1124/dmd.111.042432
  2. Barton, Hugh A.

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  3. Bauman, Jonathan

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  4. Bedwell, David W.

    1. You have access
      Ablation of Both Organic Cation Transporter (Oct)1 and Oct2 Alters Metformin Pharmacokinetics but Has No Effect on Tissue Drug Exposure and Pharmacodynamics
      J. William Higgins, David W. Bedwell and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition June 2012, 40 (6) 1170-1177; DOI: https://doi.org/10.1124/dmd.112.044875
  5. Bi, Yi-an

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  6. Burhenne, Jürgen

    1. You have access
      Drug Interaction of Efavirenz and Midazolam: Efavirenz Activates the CYP3A-Mediated Midazolam 1′-Hydroxylation In Vitro
      Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus and Jürgen Burhenne
      Drug Metabolism and Disposition June 2012, 40 (6) 1178-1182; DOI: https://doi.org/10.1124/dmd.111.043844
  7. Busacca, Carl A.

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354

C

  1. Chang, Thomas K. H.

    1. You have access
      Selective Agonism of Human Pregnane X Receptor by Individual Ginkgolides
      Aik Jiang Lau, Guixiang Yang, Chun Wei Yap and Thomas K. H. Chang
      Drug Metabolism and Disposition June 2012, 40 (6) 1113-1121; DOI: https://doi.org/10.1124/dmd.112.045013
  2. Chen, Yue

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  3. Cheng, Xingguo

    1. You have access
      Transcription Factor-Mediated Regulation of Carboxylesterase Enzymes in Livers of Mice
      Youcai Zhang, Xingguo Cheng, Lauren Aleksunes and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1191-1197; DOI: https://doi.org/10.1124/dmd.111.043877
  4. Csanaky, Iván L.

    1. You have access
      Effects of Aging on mRNA Profiles for Drug-Metabolizing Enzymes and Transporters in Livers of Male and Female Mice
      Zidong Donna Fu, Iván L. Csanaky and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1216-1225; DOI: https://doi.org/10.1124/dmd.111.044461
  5. Cui, Julia Yue

    1. You have access
      Ontogeny of Novel Cytochrome P450 Gene Isoforms during Postnatal Liver Maturation in Mice
      Julia Yue Cui, Helen J. Renaud and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1226-1237; DOI: https://doi.org/10.1124/dmd.111.042697

D

  1. D'Agostino, Jaime

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  2. de Graaf, Inge A. M.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438
  3. Dhakal, Ishwori B.

    1. You have access
      Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
      Vineetha Koroth Edavana, Ishwori B. Dhakal, Xinfeng Yu, Suzanne Williams and Susan Kadlubar
      Drug Metabolism and Disposition June 2012, 40 (6) 1210-1215; DOI: https://doi.org/10.1124/dmd.111.044040
  4. Ding, Xinxin

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  5. Dockens, Randy C.

    1. You have access
      In Vitro and In Vivo Metabolism and Pharmacokinetics of BMS-562086, a Potent and Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist
      Lian Zhou, Randy C. Dockens, Peggy Liu-Kreyche, Scott J. Grossman and Ramaswamy A. Iyer
      Drug Metabolism and Disposition June 2012, 40 (6) 1093-1103; DOI: https://doi.org/10.1124/dmd.111.043596
  6. Dorff, Peter

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636
  7. Duan, Ru

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513

E

  1. Edavana, Vineetha Koroth

    1. You have access
      Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
      Vineetha Koroth Edavana, Ishwori B. Dhakal, Xinfeng Yu, Suzanne Williams and Susan Kadlubar
      Drug Metabolism and Disposition June 2012, 40 (6) 1210-1215; DOI: https://doi.org/10.1124/dmd.111.044040
  2. El-Kattan, Ayman F.

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  3. Elmore, Charles S.

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636
  4. Elmquist, William F.

    1. You have access
      Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
      Sagar Agarwal, Yasuo Uchida, Rajendar K. Mittapalli, Ramola Sane, Tetsuya Terasaki and William F. Elmquist
      Drug Metabolism and Disposition June 2012, 40 (6) 1164-1169; DOI: https://doi.org/10.1124/dmd.112.044719
  5. Eng, Heather

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  6. Eriksson, Magnus C.

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354

F

  1. Fenner, Katherine S.

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  2. Fu, Zidong Donna

    1. You have access
      Effects of Aging on mRNA Profiles for Drug-Metabolizing Enzymes and Transporters in Livers of Male and Female Mice
      Zidong Donna Fu, Iván L. Csanaky and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1216-1225; DOI: https://doi.org/10.1124/dmd.111.044461
  3. Fukami, Tatsuki

    1. You have access
      Contributions of Arylacetamide Deacetylase and Carboxylesterase 2 to Flutamide Hydrolysis in Human Liver
      Yuki Kobayashi, Tatsuki Fukami, Mai Shimizu, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1080-1084; DOI: https://doi.org/10.1124/dmd.112.044537
    2. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883

G

  1. Ganapathy, Vadivel

    1. You have access
      Electrophysiological Characterization of the Polyspecific Organic Cation Transporter Plasma Membrane Monoamine Transporter
      Shiro Itagaki, Vadivel Ganapathy, Horace T. B. Ho, Mingyan Zhou, Ellappan Babu and Joanne Wang
      Drug Metabolism and Disposition June 2012, 40 (6) 1138-1143; DOI: https://doi.org/10.1124/dmd.111.042432
  2. Grimm, Scott W.

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636
  3. Groothuis, Geny M. M.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438
  4. Grossman, Scott J.

    1. You have access
      In Vitro and In Vivo Metabolism and Pharmacokinetics of BMS-562086, a Potent and Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist
      Lian Zhou, Randy C. Dockens, Peggy Liu-Kreyche, Scott J. Grossman and Ramaswamy A. Iyer
      Drug Metabolism and Disposition June 2012, 40 (6) 1093-1103; DOI: https://doi.org/10.1124/dmd.111.043596
  5. Gu, Chungang

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636
  6. Gunewardena, Sumedha S.

    1. You have access
      RNA Sequencing Reveals Dynamic Changes of mRNA Abundance of Cytochromes P450 and Their Alternative Transcripts during Mouse Liver Development
      Lai Peng, Byunggil Yoo, Sumedha S. Gunewardena, Hong Lu, Curtis D. Klaassen and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2012, 40 (6) 1198-1209; DOI: https://doi.org/10.1124/dmd.112.045088
  7. Guo, Haifang

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513

H

  1. Haefeli, Walter E.

    1. You have access
      Drug Interaction of Efavirenz and Midazolam: Efavirenz Activates the CYP3A-Mediated Midazolam 1′-Hydroxylation In Vitro
      Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus and Jürgen Burhenne
      Drug Metabolism and Disposition June 2012, 40 (6) 1178-1182; DOI: https://doi.org/10.1124/dmd.111.043844
  2. Hansel, Steven

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  3. Higgins, J. William

    1. You have access
      Ablation of Both Organic Cation Transporter (Oct)1 and Oct2 Alters Metformin Pharmacokinetics but Has No Effect on Tissue Drug Exposure and Pharmacodynamics
      J. William Higgins, David W. Bedwell and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition June 2012, 40 (6) 1170-1177; DOI: https://doi.org/10.1124/dmd.112.044875
  4. Ho, Horace T. B.

    1. You have access
      Electrophysiological Characterization of the Polyspecific Organic Cation Transporter Plasma Membrane Monoamine Transporter
      Shiro Itagaki, Vadivel Ganapathy, Horace T. B. Ho, Mingyan Zhou, Ellappan Babu and Joanne Wang
      Drug Metabolism and Disposition June 2012, 40 (6) 1138-1143; DOI: https://doi.org/10.1124/dmd.111.042432
  5. Hu, Nan

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513

I

  1. Itagaki, Shiro

    1. You have access
      Electrophysiological Characterization of the Polyspecific Organic Cation Transporter Plasma Membrane Monoamine Transporter
      Shiro Itagaki, Vadivel Ganapathy, Horace T. B. Ho, Mingyan Zhou, Ellappan Babu and Joanne Wang
      Drug Metabolism and Disposition June 2012, 40 (6) 1138-1143; DOI: https://doi.org/10.1124/dmd.111.042432
  2. Iyer, Ramaswamy A.

    1. You have access
      In Vitro and In Vivo Metabolism and Pharmacokinetics of BMS-562086, a Potent and Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist
      Lian Zhou, Randy C. Dockens, Peggy Liu-Kreyche, Scott J. Grossman and Ramaswamy A. Iyer
      Drug Metabolism and Disposition June 2012, 40 (6) 1093-1103; DOI: https://doi.org/10.1124/dmd.111.043596

J

  1. Ji, Chengjie

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  2. Jones, Hannah M.

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489

K

  1. Kadlubar, Susan

    1. You have access
      Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
      Vineetha Koroth Edavana, Ishwori B. Dhakal, Xinfeng Yu, Suzanne Williams and Susan Kadlubar
      Drug Metabolism and Disposition June 2012, 40 (6) 1210-1215; DOI: https://doi.org/10.1124/dmd.111.044040
  2. Kalgutkar, Amit S.

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  3. Kempshall, Sarah

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  4. Keubler, Anja

    1. You have access
      Drug Interaction of Efavirenz and Midazolam: Efavirenz Activates the CYP3A-Mediated Midazolam 1′-Hydroxylation In Vitro
      Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus and Jürgen Burhenne
      Drug Metabolism and Disposition June 2012, 40 (6) 1178-1182; DOI: https://doi.org/10.1124/dmd.111.043844
  5. Kimoto, Emi

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  6. Klaassen, Curtis D.

    1. You have access
      Transcription Factor-Mediated Regulation of Carboxylesterase Enzymes in Livers of Mice
      Youcai Zhang, Xingguo Cheng, Lauren Aleksunes and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1191-1197; DOI: https://doi.org/10.1124/dmd.111.043877
    2. You have access
      Effects of Aging on mRNA Profiles for Drug-Metabolizing Enzymes and Transporters in Livers of Male and Female Mice
      Zidong Donna Fu, Iván L. Csanaky and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1216-1225; DOI: https://doi.org/10.1124/dmd.111.044461
    3. You have access
      RNA Sequencing Reveals Dynamic Changes of mRNA Abundance of Cytochromes P450 and Their Alternative Transcripts during Mouse Liver Development
      Lai Peng, Byunggil Yoo, Sumedha S. Gunewardena, Hong Lu, Curtis D. Klaassen and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2012, 40 (6) 1198-1209; DOI: https://doi.org/10.1124/dmd.112.045088
    4. You have access
      Ontogeny of Novel Cytochrome P450 Gene Isoforms during Postnatal Liver Maturation in Mice
      Julia Yue Cui, Helen J. Renaud and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1226-1237; DOI: https://doi.org/10.1124/dmd.111.042697
  7. Kluetzman, Kerri

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  8. Kobayashi, Yuki

    1. You have access
      Contributions of Arylacetamide Deacetylase and Carboxylesterase 2 to Flutamide Hydrolysis in Human Liver
      Yuki Kobayashi, Tatsuki Fukami, Mai Shimizu, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1080-1084; DOI: https://doi.org/10.1124/dmd.112.044537
    2. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883
  9. Koenderink, Jan B.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438

L

  1. Lai, W. George

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. II. Uncovering Novel Contributions by Gut Bacteria and Aldehyde Oxidase
      Yongmei Li, Jun Xu, W. George Lai, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1130-1137; DOI: https://doi.org/10.1124/dmd.111.044362
    2. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354
  2. Lai, Yurong

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  3. Lau, Aik Jiang

    1. You have access
      Selective Agonism of Human Pregnane X Receptor by Individual Ginkgolides
      Aik Jiang Lau, Guixiang Yang, Chun Wei Yap and Thomas K. H. Chang
      Drug Metabolism and Disposition June 2012, 40 (6) 1113-1121; DOI: https://doi.org/10.1124/dmd.112.045013
  4. Li, Jia

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513
  5. Li, Lei

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  6. Li, Yongmei

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. II. Uncovering Novel Contributions by Gut Bacteria and Aldehyde Oxidase
      Yongmei Li, Jun Xu, W. George Lai, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1130-1137; DOI: https://doi.org/10.1124/dmd.111.044362
    2. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354
  7. Lin, Jianrong

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636
  8. Ling, Guoyu

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  9. Liu, Haiyan

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513
  10. Liu, Li

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513
  11. Liu, Xiaodong

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513
  12. Liu, Zhihua

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  13. Liu-Kreyche, Peggy

    1. You have access
      In Vitro and In Vivo Metabolism and Pharmacokinetics of BMS-562086, a Potent and Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist
      Lian Zhou, Randy C. Dockens, Peggy Liu-Kreyche, Scott J. Grossman and Ramaswamy A. Iyer
      Drug Metabolism and Disposition June 2012, 40 (6) 1093-1103; DOI: https://doi.org/10.1124/dmd.111.043596
  14. Lorenz, Jon C.

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354
  15. Lu, Hong

    1. You have access
      RNA Sequencing Reveals Dynamic Changes of mRNA Abundance of Cytochromes P450 and Their Alternative Transcripts during Mouse Liver Development
      Lai Peng, Byunggil Yoo, Sumedha S. Gunewardena, Hong Lu, Curtis D. Klaassen and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2012, 40 (6) 1198-1209; DOI: https://doi.org/10.1124/dmd.112.045088
  16. Luzietti, Rick

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636

M

  1. McDonald, Thomas S.

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  2. Mei, Dan

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513
  3. Mikus, Gerd

    1. You have access
      Drug Interaction of Efavirenz and Midazolam: Efavirenz Activates the CYP3A-Mediated Midazolam 1′-Hydroxylation In Vitro
      Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus and Jürgen Burhenne
      Drug Metabolism and Disposition June 2012, 40 (6) 1178-1182; DOI: https://doi.org/10.1124/dmd.111.043844
  4. Mittapalli, Rajendar K.

    1. You have access
      Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
      Sagar Agarwal, Yasuo Uchida, Rajendar K. Mittapalli, Ramola Sane, Tetsuya Terasaki and William F. Elmquist
      Drug Metabolism and Disposition June 2012, 40 (6) 1164-1169; DOI: https://doi.org/10.1124/dmd.112.044719

N

  1. Nakajima, Miki

    1. You have access
      Contributions of Arylacetamide Deacetylase and Carboxylesterase 2 to Flutamide Hydrolysis in Human Liver
      Yuki Kobayashi, Tatsuki Fukami, Mai Shimizu, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1080-1084; DOI: https://doi.org/10.1124/dmd.112.044537
    2. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883

P

  1. Peng, Lai

    1. You have access
      RNA Sequencing Reveals Dynamic Changes of mRNA Abundance of Cytochromes P450 and Their Alternative Transcripts during Mouse Liver Development
      Lai Peng, Byunggil Yoo, Sumedha S. Gunewardena, Hong Lu, Curtis D. Klaassen and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2012, 40 (6) 1198-1209; DOI: https://doi.org/10.1124/dmd.112.045088

R

  1. Renaud, Helen J.

    1. You have access
      Ontogeny of Novel Cytochrome P450 Gene Isoforms during Postnatal Liver Maturation in Mice
      Julia Yue Cui, Helen J. Renaud and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1226-1237; DOI: https://doi.org/10.1124/dmd.111.042697
  2. Russel, Frans G. M.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438

S

  1. Sane, Ramola

    1. You have access
      Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
      Sagar Agarwal, Yasuo Uchida, Rajendar K. Mittapalli, Ramola Sane, Tetsuya Terasaki and William F. Elmquist
      Drug Metabolism and Disposition June 2012, 40 (6) 1164-1169; DOI: https://doi.org/10.1124/dmd.112.044719
  2. Sevidal, Samantha

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  3. Sharma, Raman

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  4. Shimizu, Mai

    1. You have access
      Contributions of Arylacetamide Deacetylase and Carboxylesterase 2 to Flutamide Hydrolysis in Human Liver
      Yuki Kobayashi, Tatsuki Fukami, Mai Shimizu, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1080-1084; DOI: https://doi.org/10.1124/dmd.112.044537
    2. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883
  5. Siissalo, Sanna

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438

T

  1. Takamiya, Masataka

    1. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883
  2. Terasaki, Tetsuya

    1. You have access
      Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
      Sagar Agarwal, Yasuo Uchida, Rajendar K. Mittapalli, Ramola Sane, Tetsuya Terasaki and William F. Elmquist
      Drug Metabolism and Disposition June 2012, 40 (6) 1164-1169; DOI: https://doi.org/10.1124/dmd.112.044719
  3. Tweedie, Donald J.

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. II. Uncovering Novel Contributions by Gut Bacteria and Aldehyde Oxidase
      Yongmei Li, Jun Xu, W. George Lai, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1130-1137; DOI: https://doi.org/10.1124/dmd.111.044362
    2. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354

U

  1. Uchida, Yasuo

    1. You have access
      Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
      Sagar Agarwal, Yasuo Uchida, Rajendar K. Mittapalli, Ramola Sane, Tetsuya Terasaki and William F. Elmquist
      Drug Metabolism and Disposition June 2012, 40 (6) 1164-1169; DOI: https://doi.org/10.1124/dmd.112.044719

V

  1. van den Broek, Petra H. H.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438
  2. van den Heuvel, Jeroen J. M. W.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438

W

  1. Wang, Joanne

    1. You have access
      Electrophysiological Characterization of the Polyspecific Organic Cation Transporter Plasma Membrane Monoamine Transporter
      Shiro Itagaki, Vadivel Ganapathy, Horace T. B. Ho, Mingyan Zhou, Ellappan Babu and Joanne Wang
      Drug Metabolism and Disposition June 2012, 40 (6) 1138-1143; DOI: https://doi.org/10.1124/dmd.111.042432
  2. Wei, Yuan

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  3. Weiss, Johanna

    1. You have access
      Drug Interaction of Efavirenz and Midazolam: Efavirenz Activates the CYP3A-Mediated Midazolam 1′-Hydroxylation In Vitro
      Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus and Jürgen Burhenne
      Drug Metabolism and Disposition June 2012, 40 (6) 1178-1182; DOI: https://doi.org/10.1124/dmd.111.043844
  4. Weng, Yan

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  5. Whalen, Kevin M.

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  6. Whitcher-Johnstone, Andrea

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. II. Uncovering Novel Contributions by Gut Bacteria and Aldehyde Oxidase
      Yongmei Li, Jun Xu, W. George Lai, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1130-1137; DOI: https://doi.org/10.1124/dmd.111.044362
    2. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. I. Identifying an Unexpected Disproportionate Human Metabolite
      Yongmei Li, W. George Lai, Andrea Whitcher-Johnstone, Carl A. Busacca, Magnus C. Eriksson, Jon C. Lorenz and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1122-1129; DOI: https://doi.org/10.1124/dmd.111.044354
  7. Williams, Suzanne

    1. You have access
      Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
      Vineetha Koroth Edavana, Ishwori B. Dhakal, Xinfeng Yu, Suzanne Williams and Susan Kadlubar
      Drug Metabolism and Disposition June 2012, 40 (6) 1210-1215; DOI: https://doi.org/10.1124/dmd.111.044040
  8. Wittgen, Hanneke G. M.

    1. You have access
      Transport of the Coumarin Metabolite 7-Hydroxycoumarin Glucuronide Is Mediated via Multidrug Resistance-Associated Proteins 3 and 4
      Hanneke G. M. Wittgen, Jeroen J. M. W. van den Heuvel, Petra H. H. van den Broek, Sanna Siissalo, Geny M. M. Groothuis, Inge A. M. de Graaf, Jan B. Koenderink and Frans G. M. Russel
      Drug Metabolism and Disposition June 2012, 40 (6) 1076-1079; DOI: https://doi.org/10.1124/dmd.111.044438
  9. Wolford, Angela

    1. You have access
      Immune-Mediated Agranulocytosis Caused by the Cocaine Adulterant Levamisole: A Case for Reactive Metabolite(s) Involvement
      Angela Wolford, Thomas S. McDonald, Heather Eng, Steven Hansel, Yue Chen, Jonathan Bauman, Raman Sharma and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2012, 40 (6) 1067-1075; DOI: https://doi.org/10.1124/dmd.112.045021
  10. Wu, Hong

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826

X

  1. Xu, Jun

    1. You have access
      Metabolic Switching of BILR 355 in the Presence of Ritonavir. II. Uncovering Novel Contributions by Gut Bacteria and Aldehyde Oxidase
      Yongmei Li, Jun Xu, W. George Lai, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition June 2012, 40 (6) 1130-1137; DOI: https://doi.org/10.1124/dmd.111.044362

Y

  1. Yang, Guixiang

    1. You have access
      Selective Agonism of Human Pregnane X Receptor by Individual Ginkgolides
      Aik Jiang Lau, Guixiang Yang, Chun Wei Yap and Thomas K. H. Chang
      Drug Metabolism and Disposition June 2012, 40 (6) 1113-1121; DOI: https://doi.org/10.1124/dmd.112.045013
  2. Yao, Yunyi

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  3. Yap, Chun Wei

    1. You have access
      Selective Agonism of Human Pregnane X Receptor by Individual Ginkgolides
      Aik Jiang Lau, Guixiang Yang, Chun Wei Yap and Thomas K. H. Chang
      Drug Metabolism and Disposition June 2012, 40 (6) 1113-1121; DOI: https://doi.org/10.1124/dmd.112.045013
  4. Yokoi, Tsuyoshi

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      Contributions of Arylacetamide Deacetylase and Carboxylesterase 2 to Flutamide Hydrolysis in Human Liver
      Yuki Kobayashi, Tatsuki Fukami, Mai Shimizu, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1080-1084; DOI: https://doi.org/10.1124/dmd.112.044537
    2. You have access
      A Novel Polymorphic Allele of Human Arylacetamide Deacetylase Leads to Decreased Enzyme Activity
      Mai Shimizu, Tatsuki Fukami, Yuki Kobayashi, Masataka Takamiya, Yasuhiro Aoki, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition June 2012, 40 (6) 1183-1190; DOI: https://doi.org/10.1124/dmd.112.044883
  5. Yoo, Byunggil

    1. You have access
      RNA Sequencing Reveals Dynamic Changes of mRNA Abundance of Cytochromes P450 and Their Alternative Transcripts during Mouse Liver Development
      Lai Peng, Byunggil Yoo, Sumedha S. Gunewardena, Hong Lu, Curtis D. Klaassen and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2012, 40 (6) 1198-1209; DOI: https://doi.org/10.1124/dmd.112.045088
  6. Yu, Xinfeng

    1. You have access
      Sulfation of 4-Hydroxy Toremifene: Individual Variability, Isoform Specificity, and Contribution to Toremifene Pharmacogenomics
      Vineetha Koroth Edavana, Ishwori B. Dhakal, Xinfeng Yu, Suzanne Williams and Susan Kadlubar
      Drug Metabolism and Disposition June 2012, 40 (6) 1210-1215; DOI: https://doi.org/10.1124/dmd.111.044040

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. You have access
      Ablation of Both Organic Cation Transporter (Oct)1 and Oct2 Alters Metformin Pharmacokinetics but Has No Effect on Tissue Drug Exposure and Pharmacodynamics
      J. William Higgins, David W. Bedwell and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition June 2012, 40 (6) 1170-1177; DOI: https://doi.org/10.1124/dmd.112.044875
  2. Zhang, Hui

    1. You have access
      In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation
      Yi-an Bi, Emi Kimoto, Samantha Sevidal, Hannah M. Jones, Hugh A. Barton, Sarah Kempshall, Kevin M. Whalen, Hui Zhang, Chengjie Ji, Katherine S. Fenner, Ayman F. El-Kattan and Yurong Lai
      Drug Metabolism and Disposition June 2012, 40 (6) 1085-1092; DOI: https://doi.org/10.1124/dmd.111.043489
  3. Zhang, Qing-Yu

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  4. Zhang, Xiuling

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
  5. Zhang, Youcai

    1. You have access
      Transcription Factor-Mediated Regulation of Carboxylesterase Enzymes in Livers of Mice
      Youcai Zhang, Xingguo Cheng, Lauren Aleksunes and Curtis D. Klaassen
      Drug Metabolism and Disposition June 2012, 40 (6) 1191-1197; DOI: https://doi.org/10.1124/dmd.111.043877
  6. Zhong, Xiao-bo

    1. You have access
      RNA Sequencing Reveals Dynamic Changes of mRNA Abundance of Cytochromes P450 and Their Alternative Transcripts during Mouse Liver Development
      Lai Peng, Byunggil Yoo, Sumedha S. Gunewardena, Hong Lu, Curtis D. Klaassen and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2012, 40 (6) 1198-1209; DOI: https://doi.org/10.1124/dmd.112.045088
  7. Zhong, Zeyu

    1. You have access
      Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus
      Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong and Xiaodong Liu
      Drug Metabolism and Disposition June 2012, 40 (6) 1104-1112; DOI: https://doi.org/10.1124/dmd.111.043513
  8. Zhou, Diansong

    1. You have access
      Metabolism of a G Protein-Coupled Receptor Modulator, Including Two Major 1,2,4-Oxadiazole Ring-Opened Metabolites and a Rearranged Cysteine-Piperazine Adduct
      Chungang Gu, Charles S. Elmore, Jianrong Lin, Diansong Zhou, Rick Luzietti, Peter Dorff and Scott W. Grimm
      Drug Metabolism and Disposition June 2012, 40 (6) 1151-1163; DOI: https://doi.org/10.1124/dmd.112.044636
  9. Zhou, Lian

    1. You have access
      In Vitro and In Vivo Metabolism and Pharmacokinetics of BMS-562086, a Potent and Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist
      Lian Zhou, Randy C. Dockens, Peggy Liu-Kreyche, Scott J. Grossman and Ramaswamy A. Iyer
      Drug Metabolism and Disposition June 2012, 40 (6) 1093-1103; DOI: https://doi.org/10.1124/dmd.111.043596
  10. Zhou, Mingyan

    1. You have access
      Electrophysiological Characterization of the Polyspecific Organic Cation Transporter Plasma Membrane Monoamine Transporter
      Shiro Itagaki, Vadivel Ganapathy, Horace T. B. Ho, Mingyan Zhou, Ellappan Babu and Joanne Wang
      Drug Metabolism and Disposition June 2012, 40 (6) 1138-1143; DOI: https://doi.org/10.1124/dmd.111.042432
  11. Zhou, Xin

    1. You have access
      Generation and Characterization of a CYP2A13/2B6/2F1-Transgenic Mouse Model
      Yuan Wei, Hong Wu, Lei Li, Zhihua Liu, Xin Zhou, Qing-Yu Zhang, Yan Weng, Jaime D'Agostino, Guoyu Ling, Xiuling Zhang, Kerri Kluetzman, Yunyi Yao and Xinxin Ding
      Drug Metabolism and Disposition June 2012, 40 (6) 1144-1150; DOI: https://doi.org/10.1124/dmd.112.044826
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Drug Metabolism and Disposition: 40 (6)
Drug Metabolism and Disposition
Vol. 40, Issue 6
1 Jun 2012
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