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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

July 01, 2012; Volume 40,Issue 7
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Aidasani, Divesh K.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  2. Albaugh, Daniel R.

    1. You have access
      Time-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell Systems
      Daniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew Hutzler
      Drug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
  3. Aleksunes, Lauren M.

    1. You have access
      Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null Mice
      Lauren M. Aleksunes and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2012, 40 (7) 1366-1379; DOI: https://doi.org/10.1124/dmd.112.045112
  4. Argikar, Upendra A.

    1. You have access
      Unusual Glucuronides
      Upendra A. Argikar
      Drug Metabolism and Disposition July 2012, 40 (7) 1239-1251; DOI: https://doi.org/10.1124/dmd.112.045096
  5. Arias, Agostina

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339

B

  1. Bang-Andersen, Benny

    1. You have access
      Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004
      Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
      Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
  2. Barros, Anthony

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  3. Beijnen, Jos H.

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  4. Bonacorsi, Samuel J.

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  5. Boulton, David W.

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  6. Bourne, David W. A.

    1. You have access
      Nano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced Clearance
      Rajendra S. Kadam, David W. A. Bourne and Uday B. Kompella
      Drug Metabolism and Disposition July 2012, 40 (7) 1380-1388; DOI: https://doi.org/10.1124/dmd.112.044925
  7. Brée, Françoise

    1. You have access
      In Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing Enzymes
      Verònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271

C

  1. Cao, Kai

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  2. Catania, Viviana A.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
  3. Chan, Eric Chun Yong

    1. You have access
      Interaction of Lapatinib with Cytochrome P450 3A5
      Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. Nelson
      Drug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
  4. Chen, Xiaomei

    1. You have access
      Species-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1
      Yongjun Hu, Xiaomei Chen and David E. Smith
      Drug Metabolism and Disposition July 2012, 40 (7) 1328-1335; DOI: https://doi.org/10.1124/dmd.111.044263
  5. Chen, Xiaoqi

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  6. Christopher, Lisa J.

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  7. Chua, Teck Beng

    1. You have access
      Interaction of Lapatinib with Cytochrome P450 3A5
      Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. Nelson
      Drug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
  8. Coleman, Tanya

    1. You have access
      Probabilistic Orthology Analysis of the ATP-Binding Cassette Transporters: Implications for the Development of Multiple Drug Resistance Phenotype
      Ciaran Fisher, Tanya Coleman and Nick Plant
      Drug Metabolism and Disposition July 2012, 40 (7) 1397-1402; DOI: https://doi.org/10.1124/dmd.112.045062
  9. Collier, Abby C.

    1. You have access
      Neonatal Development of Hepatic UGT1A9: Implications of Pediatric Pharmacokinetics
      Shogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. Collier
      Drug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
  10. Coughtrie, Michael W. H.

    1. You have access
      Neonatal Development of Hepatic UGT1A9: Implications of Pediatric Pharmacokinetics
      Shogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. Collier
      Drug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752

D

  1. Dalgaard, Lars

    1. You have access
      Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004
      Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
      Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
  2. Darwish, Mona

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  3. Deeley, Roger G.

    1. You have access
      Effect of Multiple Cysteine Substitutions on the Functionality of Human Multidrug Resistance Protein 1 Expressed in Human Embryonic Kidney 293 Cells: Identification of Residues Essential for Function
      Lei Qin, Shui-Pang Tam and Roger G. Deeley
      Drug Metabolism and Disposition July 2012, 40 (7) 1403-1413; DOI: https://doi.org/10.1124/dmd.112.044867
  4. Dickmann, Leslie J.

    1. You have access
      In Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic Properties
      Leslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. Lin
      Drug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
  5. Dubbelman, Anne-Charlotte

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229

F

  1. Fisher, Ciaran

    1. You have access
      Probabilistic Orthology Analysis of the ATP-Binding Cassette Transporters: Implications for the Development of Multiple Drug Resistance Phenotype
      Ciaran Fisher, Tanya Coleman and Nick Plant
      Drug Metabolism and Disposition July 2012, 40 (7) 1397-1402; DOI: https://doi.org/10.1124/dmd.112.045062
  2. Fisher, Michael B.

    1. You have access
      Time-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell Systems
      Daniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew Hutzler
      Drug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
  3. Fullenwider, Cody L.

    1. You have access
      Time-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell Systems
      Daniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew Hutzler
      Drug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644

G

  1. Galetin, Aleksandra

    1. You have access
      A Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro Clearance
      Carolina Säll, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
  2. Gandhi, Yash A.

    1. You have access
      Reevaluation of a Quantitative Structure Pharmacokinetic Model for Biliary Excretion in Rats
      Yash A. Gandhi and Marilyn E. Morris
      Drug Metabolism and Disposition July 2012, 40 (7) 1259-1262; DOI: https://doi.org/10.1124/dmd.112.044842
  3. Gao, Hongying

    1. You have access
      A Simple Liquid Chromatography-Tandem Mass Spectrometry Method to Determine Relative Plasma Exposures of Drug Metabolites across Species for Metabolite Safety Assessments (Metabolites in Safety Testing). II. Application to Unstable Metabolites
      Hongying Gao and R. Scott Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1290-1296; DOI: https://doi.org/10.1124/dmd.112.044552

H

  1. Hellriegel, Edward

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  2. Henne, Kirk R.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  3. Ho, Han Kiat

    1. You have access
      Interaction of Lapatinib with Cytochrome P450 3A5
      Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. Nelson
      Drug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
  4. Houston, J. Brian

    1. You have access
      A Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro Clearance
      Carolina Säll, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
  5. Hu, Yongjun

    1. You have access
      Species-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1
      Yongjun Hu, Xiaomei Chen and David E. Smith
      Drug Metabolism and Disposition July 2012, 40 (7) 1328-1335; DOI: https://doi.org/10.1124/dmd.111.044263
  6. Humphreys, W. Griffith

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  7. Hutzler, J. Matthew

    1. You have access
      Time-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell Systems
      Daniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew Hutzler
      Drug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
  8. Hvenegaard, Mette G.

    1. You have access
      Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004
      Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
      Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610

I

  1. Ishima, Yu

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  2. Iwatsubo, Takafumi

    1. You have access
      Simultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass Spectrometry
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
  3. Iyer, Ramaswamy A.

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450

J

  1. Jansen, Robert S.

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  2. Johnson, Michael G.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  3. Jørgensen, Morten

    1. You have access
      Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004
      Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
      Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610

K

  1. Kadam, Rajendra S.

    1. You have access
      Nano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced Clearance
      Rajendra S. Kadam, David W. A. Bourne and Uday B. Kompella
      Drug Metabolism and Disposition July 2012, 40 (7) 1380-1388; DOI: https://doi.org/10.1124/dmd.112.044925
  2. Kadowaki, Daisuke

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  3. Klaassen, Curtis D.

    1. You have access
      Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null Mice
      Lauren M. Aleksunes and Curtis D. Klaassen
      Drug Metabolism and Disposition July 2012, 40 (7) 1366-1379; DOI: https://doi.org/10.1124/dmd.112.045112
  4. Klunk, Lewis

    1. You have access
      Assessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case Study
      Chandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis Klunk
      Drug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
  5. Kompella, Uday B.

    1. You have access
      Nano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced Clearance
      Rajendra S. Kadam, David W. A. Bourne and Uday B. Kompella
      Drug Metabolism and Disposition July 2012, 40 (7) 1380-1388; DOI: https://doi.org/10.1124/dmd.112.044925
  6. Kotani, Shunsuke

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617

L

  1. Li, Zhaoyang

    1. You have access
      Assessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case Study
      Chandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis Klunk
      Drug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
  2. Lin, Yvonne S.

    1. You have access
      In Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic Properties
      Leslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. Lin
      Drug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
  3. Luquita, Marcelo G.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339

M

  1. Maruyama, Toru

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  2. Mason, Andrew K.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  3. Milne, Alison M.

    1. You have access
      Neonatal Development of Hepatic UGT1A9: Implications of Pediatric Pharmacokinetics
      Shogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. Collier
      Drug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
  4. Miyagi, Shogo J.

    1. You have access
      Neonatal Development of Hepatic UGT1A9: Implications of Pediatric Pharmacokinetics
      Shogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. Collier
      Drug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
  5. Miyamoto, Yohei

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  6. Miyamura, Shigeyuki

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  7. Miyashita, Aiji

    1. You have access
      Simultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass Spectrometry
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
  8. Morris, Marilyn E.

    1. You have access
      Reevaluation of a Quantitative Structure Pharmacokinetic Model for Biliary Excretion in Rats
      Yash A. Gandhi and Marilyn E. Morris
      Drug Metabolism and Disposition July 2012, 40 (7) 1259-1262; DOI: https://doi.org/10.1124/dmd.112.044842
  9. Mottino, Aldo D.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339

N

  1. Nakajima, Makoto

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  2. Nelson, Sidney D.

    1. You have access
      Interaction of Lapatinib with Cytochrome P450 3A5
      Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. Nelson
      Drug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
  3. New, Lee Sun

    1. You have access
      Interaction of Lapatinib with Cytochrome P450 3A5
      Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. Nelson
      Drug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
  4. Noguchi, Tsuyoshi

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617

O

  1. Obach, R. Scott

    1. You have access
      A Simple Liquid Chromatography-Tandem Mass Spectrometry Method to Determine Relative Plasma Exposures of Drug Metabolites across Species for Metabolite Safety Assessments (Metabolites in Safety Testing). II. Application to Unstable Metabolites
      Hongying Gao and R. Scott Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1290-1296; DOI: https://doi.org/10.1124/dmd.112.044552
    2. You have access
      Hydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic Clearance
      Timothy J. Strelevitz, Christine C. Orozco and R. Scott Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1441-1448; DOI: https://doi.org/10.1124/dmd.112.045195
  2. Obach, Rosendo

    1. You have access
      In Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing Enzymes
      Verònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
  3. Orlandi, Cesare

    1. You have access
      Assessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case Study
      Chandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis Klunk
      Drug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
  4. Orozco, Christine C.

    1. You have access
      Hydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic Clearance
      Timothy J. Strelevitz, Christine C. Orozco and R. Scott Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1441-1448; DOI: https://doi.org/10.1124/dmd.112.045195
  5. Otagiri, Masaki

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617

P

  1. Pedersen, Henrik

    1. You have access
      Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004
      Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
      Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
  2. Peraire, Concepción

    1. You have access
      In Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing Enzymes
      Verònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
  3. Perdomo, Virginia G.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
  4. Plant, Nick

    1. You have access
      Probabilistic Orthology Analysis of the ATP-Binding Cassette Transporters: Implications for the Development of Multiple Drug Resistance Phenotype
      Ciaran Fisher, Tanya Coleman and Nick Plant
      Drug Metabolism and Disposition July 2012, 40 (7) 1397-1402; DOI: https://doi.org/10.1124/dmd.112.045062
  5. Prakash, Chandra

    1. You have access
      Assessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case Study
      Chandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis Klunk
      Drug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
  6. Püschl, Ask

    1. You have access
      Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004
      Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
      Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610

Q

  1. Qin, Lei

    1. You have access
      Effect of Multiple Cysteine Substitutions on the Functionality of Human Multidrug Resistance Protein 1 Expressed in Human Embryonic Kidney 293 Cells: Identification of Residues Essential for Function
      Lei Qin, Shui-Pang Tam and Roger G. Deeley
      Drug Metabolism and Disposition July 2012, 40 (7) 1403-1413; DOI: https://doi.org/10.1124/dmd.112.044867

R

  1. Rigalli, Juan P.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
  2. Robertson, Philmore

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  3. Rock, Dan A.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  4. Rosing, Hilde

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  5. Ruiz, María L.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339

S

  1. Säll, Carolina

    1. You have access
      A Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro Clearance
      Carolina Säll, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
  2. Sato, Yuichiro

    1. You have access
      Simultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass Spectrometry
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
  3. Schellens, Jan H. M.

    1. You have access
      Metabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]Bendamustine
      Anne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. Beijnen
      Drug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
  4. Smith, David E.

    1. You have access
      Species-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1
      Yongjun Hu, Xiaomei Chen and David E. Smith
      Drug Metabolism and Disposition July 2012, 40 (7) 1328-1335; DOI: https://doi.org/10.1124/dmd.111.044263
  5. Solà, Josep

    1. You have access
      In Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing Enzymes
      Verònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
  6. Strelevitz, Timothy J.

    1. You have access
      Hydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic Clearance
      Timothy J. Strelevitz, Christine C. Orozco and R. Scott Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1441-1448; DOI: https://doi.org/10.1124/dmd.112.045195
  7. Stresser, David M.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  8. Su, Hong

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  9. Subramanian, Raju

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708

T

  1. Tam, Shui-Pang

    1. You have access
      Effect of Multiple Cysteine Substitutions on the Functionality of Human Multidrug Resistance Protein 1 Expressed in Human Embryonic Kidney 293 Cells: Identification of Residues Essential for Function
      Lei Qin, Shui-Pang Tam and Roger G. Deeley
      Drug Metabolism and Disposition July 2012, 40 (7) 1403-1413; DOI: https://doi.org/10.1124/dmd.112.044867
  2. Teffera, Yohannes

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  3. Tonn, George R.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  4. Tran, Thuy B.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708

U

  1. Usui, Takashi

    1. You have access
      Simultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass Spectrometry
      Yuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi Usui
      Drug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054

V

  1. VandenBrink, Brooke M.

    1. You have access
      In Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic Properties
      Leslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. Lin
      Drug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
    2. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  2. Ventura, Verònica

    1. You have access
      In Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing Enzymes
      Verònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo Obach
      Drug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
  3. Villanueva, Silvina S. M.

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
  4. Vore, Mary

    1. You have access
      Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
      Silvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339

W

  1. Wang, Lifei

    1. You have access
      Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human
      Hong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
  2. Watanabe, Hiroshi

    1. You have access
      Interaction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum Albumin
      Hiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
  3. Wong, Bradley K.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
  4. Wong, Simon G.

    1. You have access
      Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme
      Kirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. Wong
      Drug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708

Y

  1. Yap, Chun Wei

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      Interaction of Lapatinib with Cytochrome P450 3A5
      Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. Nelson
      Drug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
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Drug Metabolism and Disposition: 40 (7)
Drug Metabolism and Disposition
Vol. 40, Issue 7
1 Jul 2012
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