Index by author
July 01, 2012; Volume 40,Issue 7
A
Aidasani, Divesh K.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Albaugh, Daniel R.
- You have accessTime-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell SystemsDaniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew HutzlerDrug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
Aleksunes, Lauren M.
- You have accessCoordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null MiceLauren M. Aleksunes and Curtis D. KlaassenDrug Metabolism and Disposition July 2012, 40 (7) 1366-1379; DOI: https://doi.org/10.1124/dmd.112.045112
Argikar, Upendra A.
- You have accessUnusual GlucuronidesUpendra A. ArgikarDrug Metabolism and Disposition July 2012, 40 (7) 1239-1251; DOI: https://doi.org/10.1124/dmd.112.045096
Arias, Agostina
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
B
Bang-Andersen, Benny
- You have accessIdentification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars DalgaardDrug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
Barros, Anthony
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Beijnen, Jos H.
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Bonacorsi, Samuel J.
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Boulton, David W.
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Bourne, David W. A.
- You have accessNano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced ClearanceRajendra S. Kadam, David W. A. Bourne and Uday B. KompellaDrug Metabolism and Disposition July 2012, 40 (7) 1380-1388; DOI: https://doi.org/10.1124/dmd.112.044925
Brée, Françoise
- You have accessIn Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing EnzymesVerònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo ObachDrug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
C
Cao, Kai
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Catania, Viviana A.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
Chan, Eric Chun Yong
- You have accessInteraction of Lapatinib with Cytochrome P450 3A5Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. NelsonDrug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
Chen, Xiaomei
- You have accessSpecies-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1Yongjun Hu, Xiaomei Chen and David E. SmithDrug Metabolism and Disposition July 2012, 40 (7) 1328-1335; DOI: https://doi.org/10.1124/dmd.111.044263
Chen, Xiaoqi
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Christopher, Lisa J.
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Chua, Teck Beng
- You have accessInteraction of Lapatinib with Cytochrome P450 3A5Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. NelsonDrug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
Coleman, Tanya
- You have accessProbabilistic Orthology Analysis of the ATP-Binding Cassette Transporters: Implications for the Development of Multiple Drug Resistance PhenotypeCiaran Fisher, Tanya Coleman and Nick PlantDrug Metabolism and Disposition July 2012, 40 (7) 1397-1402; DOI: https://doi.org/10.1124/dmd.112.045062
Collier, Abby C.
- You have accessNeonatal Development of Hepatic UGT1A9: Implications of Pediatric PharmacokineticsShogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. CollierDrug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
Coughtrie, Michael W. H.
- You have accessNeonatal Development of Hepatic UGT1A9: Implications of Pediatric PharmacokineticsShogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. CollierDrug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
D
Dalgaard, Lars
- You have accessIdentification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars DalgaardDrug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
Darwish, Mona
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Deeley, Roger G.
- You have accessEffect of Multiple Cysteine Substitutions on the Functionality of Human Multidrug Resistance Protein 1 Expressed in Human Embryonic Kidney 293 Cells: Identification of Residues Essential for FunctionLei Qin, Shui-Pang Tam and Roger G. DeeleyDrug Metabolism and Disposition July 2012, 40 (7) 1403-1413; DOI: https://doi.org/10.1124/dmd.112.044867
Dickmann, Leslie J.
- You have accessIn Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic PropertiesLeslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. LinDrug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
Dubbelman, Anne-Charlotte
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
F
Fisher, Ciaran
- You have accessProbabilistic Orthology Analysis of the ATP-Binding Cassette Transporters: Implications for the Development of Multiple Drug Resistance PhenotypeCiaran Fisher, Tanya Coleman and Nick PlantDrug Metabolism and Disposition July 2012, 40 (7) 1397-1402; DOI: https://doi.org/10.1124/dmd.112.045062
Fisher, Michael B.
- You have accessTime-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell SystemsDaniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew HutzlerDrug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
Fullenwider, Cody L.
- You have accessTime-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell SystemsDaniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew HutzlerDrug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
G
Galetin, Aleksandra
- You have accessA Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro ClearanceCarolina Säll, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
Gandhi, Yash A.
- You have accessReevaluation of a Quantitative Structure Pharmacokinetic Model for Biliary Excretion in RatsYash A. Gandhi and Marilyn E. MorrisDrug Metabolism and Disposition July 2012, 40 (7) 1259-1262; DOI: https://doi.org/10.1124/dmd.112.044842
Gao, Hongying
- You have accessA Simple Liquid Chromatography-Tandem Mass Spectrometry Method to Determine Relative Plasma Exposures of Drug Metabolites across Species for Metabolite Safety Assessments (Metabolites in Safety Testing). II. Application to Unstable MetabolitesHongying Gao and R. Scott ObachDrug Metabolism and Disposition July 2012, 40 (7) 1290-1296; DOI: https://doi.org/10.1124/dmd.112.044552
H
Hellriegel, Edward
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Henne, Kirk R.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Ho, Han Kiat
- You have accessInteraction of Lapatinib with Cytochrome P450 3A5Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. NelsonDrug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
Houston, J. Brian
- You have accessA Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro ClearanceCarolina Säll, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
Hu, Yongjun
- You have accessSpecies-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1Yongjun Hu, Xiaomei Chen and David E. SmithDrug Metabolism and Disposition July 2012, 40 (7) 1328-1335; DOI: https://doi.org/10.1124/dmd.111.044263
Humphreys, W. Griffith
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Hutzler, J. Matthew
- You have accessTime-Dependent Inhibition and Estimation of CYP3A Clinical Pharmacokinetic Drug-Drug Interactions Using Plated Human Cell SystemsDaniel R. Albaugh, Cody L. Fullenwider, Michael B. Fisher and J. Matthew HutzlerDrug Metabolism and Disposition July 2012, 40 (7) 1336-1344; DOI: https://doi.org/10.1124/dmd.112.044644
Hvenegaard, Mette G.
- You have accessIdentification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars DalgaardDrug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
I
Ishima, Yu
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Iwatsubo, Takafumi
- You have accessSimultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass SpectrometryYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
Iyer, Ramaswamy A.
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
J
Jansen, Robert S.
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Johnson, Michael G.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Jørgensen, Morten
- You have accessIdentification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars DalgaardDrug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
K
Kadam, Rajendra S.
- You have accessNano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced ClearanceRajendra S. Kadam, David W. A. Bourne and Uday B. KompellaDrug Metabolism and Disposition July 2012, 40 (7) 1380-1388; DOI: https://doi.org/10.1124/dmd.112.044925
Kadowaki, Daisuke
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Klaassen, Curtis D.
- You have accessCoordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null MiceLauren M. Aleksunes and Curtis D. KlaassenDrug Metabolism and Disposition July 2012, 40 (7) 1366-1379; DOI: https://doi.org/10.1124/dmd.112.045112
Klunk, Lewis
- You have accessAssessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case StudyChandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis KlunkDrug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
Kompella, Uday B.
- You have accessNano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced ClearanceRajendra S. Kadam, David W. A. Bourne and Uday B. KompellaDrug Metabolism and Disposition July 2012, 40 (7) 1380-1388; DOI: https://doi.org/10.1124/dmd.112.044925
Kotani, Shunsuke
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
L
Li, Zhaoyang
- You have accessAssessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case StudyChandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis KlunkDrug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
Lin, Yvonne S.
- You have accessIn Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic PropertiesLeslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. LinDrug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
Luquita, Marcelo G.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
M
Maruyama, Toru
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Mason, Andrew K.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Milne, Alison M.
- You have accessNeonatal Development of Hepatic UGT1A9: Implications of Pediatric PharmacokineticsShogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. CollierDrug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
Miyagi, Shogo J.
- You have accessNeonatal Development of Hepatic UGT1A9: Implications of Pediatric PharmacokineticsShogo J. Miyagi, Alison M. Milne, Michael W. H. Coughtrie and Abby C. CollierDrug Metabolism and Disposition July 2012, 40 (7) 1321-1327; DOI: https://doi.org/10.1124/dmd.111.043752
Miyamoto, Yohei
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Miyamura, Shigeyuki
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Miyashita, Aiji
- You have accessSimultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass SpectrometryYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
Morris, Marilyn E.
- You have accessReevaluation of a Quantitative Structure Pharmacokinetic Model for Biliary Excretion in RatsYash A. Gandhi and Marilyn E. MorrisDrug Metabolism and Disposition July 2012, 40 (7) 1259-1262; DOI: https://doi.org/10.1124/dmd.112.044842
Mottino, Aldo D.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
N
Nakajima, Makoto
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Nelson, Sidney D.
- You have accessInteraction of Lapatinib with Cytochrome P450 3A5Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. NelsonDrug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
New, Lee Sun
- You have accessInteraction of Lapatinib with Cytochrome P450 3A5Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. NelsonDrug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958
Noguchi, Tsuyoshi
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
O
Obach, R. Scott
- You have accessA Simple Liquid Chromatography-Tandem Mass Spectrometry Method to Determine Relative Plasma Exposures of Drug Metabolites across Species for Metabolite Safety Assessments (Metabolites in Safety Testing). II. Application to Unstable MetabolitesHongying Gao and R. Scott ObachDrug Metabolism and Disposition July 2012, 40 (7) 1290-1296; DOI: https://doi.org/10.1124/dmd.112.044552
- You have accessHydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic ClearanceTimothy J. Strelevitz, Christine C. Orozco and R. Scott ObachDrug Metabolism and Disposition July 2012, 40 (7) 1441-1448; DOI: https://doi.org/10.1124/dmd.112.045195
Obach, Rosendo
- You have accessIn Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing EnzymesVerònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo ObachDrug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
Orlandi, Cesare
- You have accessAssessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case StudyChandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis KlunkDrug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
Orozco, Christine C.
- You have accessHydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic ClearanceTimothy J. Strelevitz, Christine C. Orozco and R. Scott ObachDrug Metabolism and Disposition July 2012, 40 (7) 1441-1448; DOI: https://doi.org/10.1124/dmd.112.045195
Otagiri, Masaki
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
P
Pedersen, Henrik
- You have accessIdentification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars DalgaardDrug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
Peraire, Concepción
- You have accessIn Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing EnzymesVerònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo ObachDrug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
Perdomo, Virginia G.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
Plant, Nick
- You have accessProbabilistic Orthology Analysis of the ATP-Binding Cassette Transporters: Implications for the Development of Multiple Drug Resistance PhenotypeCiaran Fisher, Tanya Coleman and Nick PlantDrug Metabolism and Disposition July 2012, 40 (7) 1397-1402; DOI: https://doi.org/10.1124/dmd.112.045062
Prakash, Chandra
- You have accessAssessment of Exposure of Metabolites in Preclinical Species and Humans at Steady State from the Single-Dose Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies: A Case StudyChandra Prakash, Zhaoyang Li, Cesare Orlandi and Lewis KlunkDrug Metabolism and Disposition July 2012, 40 (7) 1308-1320; DOI: https://doi.org/10.1124/dmd.112.044933
Püschl, Ask
- You have accessIdentification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars DalgaardDrug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
Q
Qin, Lei
- You have accessEffect of Multiple Cysteine Substitutions on the Functionality of Human Multidrug Resistance Protein 1 Expressed in Human Embryonic Kidney 293 Cells: Identification of Residues Essential for FunctionLei Qin, Shui-Pang Tam and Roger G. DeeleyDrug Metabolism and Disposition July 2012, 40 (7) 1403-1413; DOI: https://doi.org/10.1124/dmd.112.044867
R
Rigalli, Juan P.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
Robertson, Philmore
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Rock, Dan A.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Rosing, Hilde
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Ruiz, María L.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
S
Säll, Carolina
- You have accessA Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro ClearanceCarolina Säll, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
Sato, Yuichiro
- You have accessSimultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass SpectrometryYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
Schellens, Jan H. M.
- You have accessMetabolite Profiling of Bendamustine in Urine of Cancer Patients after Administration of [14C]BendamustineAnne-Charlotte Dubbelman, Robert S. Jansen, Hilde Rosing, Mona Darwish, Edward Hellriegel, Philmore Robertson, Jan H. M. Schellens and Jos H. BeijnenDrug Metabolism and Disposition July 2012, 40 (7) 1297-1307; DOI: https://doi.org/10.1124/dmd.112.045229
Smith, David E.
- You have accessSpecies-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1Yongjun Hu, Xiaomei Chen and David E. SmithDrug Metabolism and Disposition July 2012, 40 (7) 1328-1335; DOI: https://doi.org/10.1124/dmd.111.044263
Solà, Josep
- You have accessIn Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing EnzymesVerònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo ObachDrug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
Strelevitz, Timothy J.
- You have accessHydralazine As a Selective Probe Inactivator of Aldehyde Oxidase in Human Hepatocytes: Estimation of the Contribution of Aldehyde Oxidase to Metabolic ClearanceTimothy J. Strelevitz, Christine C. Orozco and R. Scott ObachDrug Metabolism and Disposition July 2012, 40 (7) 1441-1448; DOI: https://doi.org/10.1124/dmd.112.045195
Stresser, David M.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Su, Hong
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Subramanian, Raju
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
T
Tam, Shui-Pang
- You have accessEffect of Multiple Cysteine Substitutions on the Functionality of Human Multidrug Resistance Protein 1 Expressed in Human Embryonic Kidney 293 Cells: Identification of Residues Essential for FunctionLei Qin, Shui-Pang Tam and Roger G. DeeleyDrug Metabolism and Disposition July 2012, 40 (7) 1403-1413; DOI: https://doi.org/10.1124/dmd.112.044867
Teffera, Yohannes
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Tonn, George R.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Tran, Thuy B.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
U
Usui, Takashi
- You have accessSimultaneous Absolute Protein Quantification of Carboxylesterases 1 and 2 in Human Liver Tissue Fractions using Liquid Chromatography-Tandem Mass SpectrometryYuichiro Sato, Aiji Miyashita, Takafumi Iwatsubo and Takashi UsuiDrug Metabolism and Disposition July 2012, 40 (7) 1389-1396; DOI: https://doi.org/10.1124/dmd.112.045054
V
VandenBrink, Brooke M.
- You have accessIn Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic PropertiesLeslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. LinDrug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Ventura, Verònica
- You have accessIn Vitro Evaluation of the Interaction Potential of Irosustat with Drug-Metabolizing EnzymesVerònica Ventura, Josep Solà, Concepción Peraire, Françoise Brée and Rosendo ObachDrug Metabolism and Disposition July 2012, 40 (7) 1268-1278; DOI: https://doi.org/10.1124/dmd.111.044271
Villanueva, Silvina S. M.
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
Vore, Mary
- You have accessEffect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzeneSilvina S. M. Villanueva, Virginia G. Perdomo, María L. Ruiz, Juan P. Rigalli, Agostina Arias, Marcelo G. Luquita, Mary Vore, Viviana A. Catania and Aldo D. MottinoDrug Metabolism and Disposition July 2012, 40 (7) 1252-1258; DOI: https://doi.org/10.1124/dmd.111.044339
W
Wang, Lifei
- You have accessCharacterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in HumanHong Su, David W. Boulton, Anthony Barros, Lifei Wang, Kai Cao, Samuel J. Bonacorsi, Ramaswamy A. Iyer, W. Griffith Humphreys and Lisa J. ChristopherDrug Metabolism and Disposition July 2012, 40 (7) 1345-1356; DOI: https://doi.org/10.1124/dmd.112.045450
Watanabe, Hiroshi
- You have accessInteraction between Two Sulfate-Conjugated Uremic Toxins, p-Cresyl Sulfate and Indoxyl Sulfate, during Binding with Human Serum AlbuminHiroshi Watanabe, Tsuyoshi Noguchi, Yohei Miyamoto, Daisuke Kadowaki, Shunsuke Kotani, Makoto Nakajima, Shigeyuki Miyamura, Yu Ishima, Masaki Otagiri and Toru MaruyamaDrug Metabolism and Disposition July 2012, 40 (7) 1423-1428; DOI: https://doi.org/10.1124/dmd.112.045617
Wong, Bradley K.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Wong, Simon G.
- You have accessSequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the EnzymeKirk R. Henne, Thuy B. Tran, Brooke M. VandenBrink, Dan A. Rock, Divesh K. Aidasani, Raju Subramanian, Andrew K. Mason, David M. Stresser, Yohannes Teffera, Simon G. Wong, Michael G. Johnson, Xiaoqi Chen, George R. Tonn and Bradley K. WongDrug Metabolism and Disposition July 2012, 40 (7) 1429-1440; DOI: https://doi.org/10.1124/dmd.112.045708
Y
Yap, Chun Wei
- You have accessInteraction of Lapatinib with Cytochrome P450 3A5Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho and Sidney D. NelsonDrug Metabolism and Disposition July 2012, 40 (7) 1414-1422; DOI: https://doi.org/10.1124/dmd.112.044958