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A Comprehensive Assessment of Repaglinide Metabolic Pathways: Impact of Choice of In Vitro System and Relative Enzyme Contribution to In Vitro Clearance

Carolina Säll, J. Brian Houston and Aleksandra Galetin
Drug Metabolism and Disposition July 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286

Article Information

vol. 40 no. 7 1279-1289
DOI 
https://doi.org/10.1124/dmd.112.045286
PubMed 
22451699
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 27, 2012
  • Accepted March 26, 2012
  • Published online June 20, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Carolina Säll,
  2. J. Brian Houston and
  3. Aleksandra Galetin
  1. Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
  1. Address correspondence to:
    Aleksandra Galetin, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, UK. E-mail: aleksandra.galetin{at}manchester.ac.uk
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COMPREHENSIVE ASSESSMENT OF REPAGLINIDE METABOLISM

Carolina Säll, J. Brian Houston and Aleksandra Galetin
Drug Metabolism and Disposition July 1, 2012, 40 (7) 1279-1289; DOI: https://doi.org/10.1124/dmd.112.045286
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