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Research ArticleArticle

Identification of the Cytochrome P450 and Other Enzymes Involved in the In Vitro Oxidative Metabolism of a Novel Antidepressant, Lu AA21004

Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
Drug Metabolism and Disposition July 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610

Article Information

vol. 40 no. 7 1357-1365
DOI 
https://doi.org/10.1124/dmd.112.044610
PubMed 
22496396
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 19, 2012
  • Accepted April 11, 2012
  • Published online June 20, 2012.

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Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mette G. Hvenegaard,
  2. Benny Bang-Andersen,
  3. Henrik Pedersen,
  4. Morten Jørgensen,
  5. Ask Püschl and
  6. Lars Dalgaard
  1. Department of Drug Metabolism (M.G.H., L.D.) and Division of Discovery Chemistry and DMPK, H. Lundbeck A/S, Valby, Denmark (B.B.-A., H.P., M.J., A.P.)
  1. Address correspondence to:
    Dr. Mette G. Hvenegaard, Department of Drug Metabolism, H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark. E-mail: mgh{at}lundbeck.com
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ENZYMES INVOLVED IN THE METABOLISM OF Lu AA21004 IN VITRO

Mette G. Hvenegaard, Benny Bang-Andersen, Henrik Pedersen, Morten Jørgensen, Ask Püschl and Lars Dalgaard
Drug Metabolism and Disposition July 1, 2012, 40 (7) 1357-1365; DOI: https://doi.org/10.1124/dmd.112.044610
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