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Index by author

August 01, 2012; Volume 40,Issue 8

A

  1. Agarwal, Sagar

    1. Brain Distribution and Bioavailability of Elacridar after Different Routes of Administration in the Mouse
      Ramola Sane, Sagar Agarwal and William F. Elmquist
      Drug Metabolism and Disposition August 2012, 40 (8) 1612-1619; DOI: https://doi.org/10.1124/dmd.112.045930

  2. Annaert, Pieter

    1. Boosting of HIV Protease Inhibitors by Ritonavir in the Intestine: The Relative Role of Cytochrome P450 and P-Glycoprotein Inhibition Based on Caco-2 Monolayers versus In Situ Intestinal Perfusion in Mice
      Nico Holmstock, Pieter Annaert and Patrick Augustijns
      Drug Metabolism and Disposition August 2012, 40 (8) 1473-1477; DOI: https://doi.org/10.1124/dmd.112.044677

  3. Augustijns, Patrick

    1. Boosting of HIV Protease Inhibitors by Ritonavir in the Intestine: The Relative Role of Cytochrome P450 and P-Glycoprotein Inhibition Based on Caco-2 Monolayers versus In Situ Intestinal Perfusion in Mice
      Nico Holmstock, Pieter Annaert and Patrick Augustijns
      Drug Metabolism and Disposition August 2012, 40 (8) 1473-1477; DOI: https://doi.org/10.1124/dmd.112.044677

B

  1. Bachir-Cherif, Dalila

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443

  2. Barton, Patrick

    1. The Development, Characterization, and Application of an OATP1B1 Inhibition Assay in Drug Discovery
      Matthew G. Soars, Patrick Barton, Manfred Ismair, Rachael Jupp and Robert J. Riley
      Drug Metabolism and Disposition August 2012, 40 (8) 1641-1648; DOI: https://doi.org/10.1124/dmd.111.042382

  3. Belli, Sara

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443
    2. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

C

  1. Chang, George

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  2. Chanteux, H.

    1. Effect of Gemfibrozil on the Metabolism of Brivaracetam In Vitro and in Human Subjects
      J.-M. Nicolas, H. Chanteux, M. Rosa, S. Watanabe and A. Stockis
      Drug Metabolism and Disposition August 2012, 40 (8) 1466-1472; DOI: https://doi.org/10.1124/dmd.112.045328

  3. Chapman, John D.

    1. Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the meta-Isomer of Acetaminophen
      John P. Harrelson, Brendan D. Stamper, John D. Chapman, David R. Goodlett and Sidney D. Nelson
      Drug Metabolism and Disposition August 2012, 40 (8) 1460-1465; DOI: https://doi.org/10.1124/dmd.112.045492

  4. Chen, Chien-Kuang

    1. Metabolism of (2S)-Pterosin A: Identification of the Phase I and Phase II Metabolites in Rat Urine
      Yung-Ping Lee, Feng-Lin Hsu, Jaw-Jou Kang, Chien-Kuang Chen and Shoei-Sheng Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.045039

  5. Chen, Xiaoyan

    1. Identification of the ortho-Benzoquinone Intermediate of 5-O-Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations
      Cen Xie, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2012, 40 (8) 1628-1640; DOI: https://doi.org/10.1124/dmd.112.045641

  6. Chiba, Masato

    1. A Novel Method for the Determination of the Site of Glucuronidation by Ion Mobility Spectrometry-Mass Spectrometry
      Atsushi Shimizu, Tomoyuki Ohe and Masato Chiba
      Drug Metabolism and Disposition August 2012, 40 (8) 1456-1459; DOI: https://doi.org/10.1124/dmd.112.045435

  7. Chow, Chi-Kin

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

  8. Clench, Malcolm R.

    1. Reaction of Homopiperazine with Endogenous Formaldehyde: A Carbon Hydrogen Addition Metabolite/Product Identified in Rat Urine and Blood
      Scott Martin, Eva M. Lenz, Dave Temesi, Martin Wild and Malcolm R. Clench
      Drug Metabolism and Disposition August 2012, 40 (8) 1478-1486; DOI: https://doi.org/10.1124/dmd.112.044917

  9. Cook, Ian T.

    1. Potent Inhibition of Human Sulfotransferase 1A1 by 17α-Ethinylestradiol: Role of 3′-Phosphoadenosine 5′-Phosphosulfate Binding and Structural Rearrangements in Regulating Inhibition and Activity
      Katie Jo Rohn, Ian T. Cook, Thomas S. Leyh, Susan A. Kadlubar and Charles N. Falany
      Drug Metabolism and Disposition August 2012, 40 (8) 1588-1595; DOI: https://doi.org/10.1124/dmd.112.045583

D

  1. Dalvie, Deepak

    1. Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide
      Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang and Ping Kang
      Drug Metabolism and Disposition August 2012, 40 (8) 1575-1587; DOI: https://doi.org/10.1124/dmd.112.045823

  2. Datta-Mannan, Amita

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

  3. Dickinson, Craig

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

  4. Dolgos, Hugues

    1. Evaluation of the Use of Static and Dynamic Models to Predict Drug-Drug Interaction and Its Associated Variability: Impact on Drug Discovery and Early Development
      Sheila Annie Peters, Patricia E. Schroeder, Nagdeep Giri and Hugues Dolgos
      Drug Metabolism and Disposition August 2012, 40 (8) 1495-1507; DOI: https://doi.org/10.1124/dmd.112.044602

  5. Driver, David

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

E

  1. El-Kattan, Ayman F.

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  2. Elmquist, William F.

    1. Brain Distribution and Bioavailability of Elacridar after Different Routes of Administration in the Mouse
      Ramola Sane, Sagar Agarwal and William F. Elmquist
      Drug Metabolism and Disposition August 2012, 40 (8) 1612-1619; DOI: https://doi.org/10.1124/dmd.112.045930

F

  1. Falany, Charles N.

    1. Potent Inhibition of Human Sulfotransferase 1A1 by 17α-Ethinylestradiol: Role of 3′-Phosphoadenosine 5′-Phosphosulfate Binding and Structural Rearrangements in Regulating Inhibition and Activity
      Katie Jo Rohn, Ian T. Cook, Thomas S. Leyh, Susan A. Kadlubar and Charles N. Falany
      Drug Metabolism and Disposition August 2012, 40 (8) 1588-1595; DOI: https://doi.org/10.1124/dmd.112.045583

  2. Feng, Bo

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  3. Fu, Angel Y. N.

    1. Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
      Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
      Drug Metabolism and Disposition August 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245

  4. Fukami, Tatsuki

    1. Preparation of a Specific Monoclonal Antibody against Human UDP-Glucuronosyltransferase (UGT) 1A9 and Evaluation of UGT1A9 Protein Levels in Human Tissues
      Shingo Oda, Miki Nakajima, Masahiko Hatakeyama, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition August 2012, 40 (8) 1620-1627; DOI: https://doi.org/10.1124/dmd.112.045625

  5. Funk, Christoph

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

G

  1. Gao, Song

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

  2. Giri, Nagdeep

    1. Evaluation of the Use of Static and Dynamic Models to Predict Drug-Drug Interaction and Its Associated Variability: Impact on Drug Discovery and Early Development
      Sheila Annie Peters, Patricia E. Schroeder, Nagdeep Giri and Hugues Dolgos
      Drug Metabolism and Disposition August 2012, 40 (8) 1495-1507; DOI: https://doi.org/10.1124/dmd.112.044602

  3. Goodlett, David R.

    1. Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the meta-Isomer of Acetaminophen
      John P. Harrelson, Brendan D. Stamper, John D. Chapman, David R. Goodlett and Sidney D. Nelson
      Drug Metabolism and Disposition August 2012, 40 (8) 1460-1465; DOI: https://doi.org/10.1124/dmd.112.045492

  4. Goosen, Theunis C.

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  5. Grillo, Mark P.

    1. Metabolic Activation of Mefenamic Acid Leading to Mefenamyl-S-Acyl-Glutathione Adduct Formation In Vitro and In Vivo in Rat
      Mark P. Grillo, Michelle Tadano Lohr and Jill C. M. Wait
      Drug Metabolism and Disposition August 2012, 40 (8) 1515-1526; DOI: https://doi.org/10.1124/dmd.112.046102

H

  1. Haller, Stephanie

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443

  2. Harrelson, John P.

    1. Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the meta-Isomer of Acetaminophen
      John P. Harrelson, Brendan D. Stamper, John D. Chapman, David R. Goodlett and Sidney D. Nelson
      Drug Metabolism and Disposition August 2012, 40 (8) 1460-1465; DOI: https://doi.org/10.1124/dmd.112.045492

  3. Hatakeyama, Masahiko

    1. Preparation of a Specific Monoclonal Antibody against Human UDP-Glucuronosyltransferase (UGT) 1A9 and Evaluation of UGT1A9 Protein Levels in Human Tissues
      Shingo Oda, Miki Nakajima, Masahiko Hatakeyama, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition August 2012, 40 (8) 1620-1627; DOI: https://doi.org/10.1124/dmd.112.045625

  4. Heinig, Katja

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  5. Hoffmann, Gerhard

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  6. Holmstock, Nico

    1. Boosting of HIV Protease Inhibitors by Ritonavir in the Intestine: The Relative Role of Cytochrome P450 and P-Glycoprotein Inhibition Based on Caco-2 Monolayers versus In Situ Intestinal Perfusion in Mice
      Nico Holmstock, Pieter Annaert and Patrick Augustijns
      Drug Metabolism and Disposition August 2012, 40 (8) 1473-1477; DOI: https://doi.org/10.1124/dmd.112.044677

  7. Houston, J. Brian

    1. Utility of Drug Depletion-Time Profiles in Isolated Hepatocytes for Accessing Hepatic Uptake Clearance: Identifying Rate-Limiting Steps and Role of Passive Processes
      Emilie Jigorel and J. Brian Houston
      Drug Metabolism and Disposition August 2012, 40 (8) 1596-1602; DOI: https://doi.org/10.1124/dmd.112.045732

  8. Hsu, Feng-Lin

    1. Metabolism of (2S)-Pterosin A: Identification of the Phase I and Phase II Metabolites in Rat Urine
      Yung-Ping Lee, Feng-Lin Hsu, Jaw-Jou Kang, Chien-Kuang Chen and Shoei-Sheng Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.045039

  9. Hu, Ming

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

  10. Hu, Qiyue

    1. Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide
      Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang and Ping Kang
      Drug Metabolism and Disposition August 2012, 40 (8) 1575-1587; DOI: https://doi.org/10.1124/dmd.112.045823

  11. Hu, Zhe-Yi

    1. In Vivo Information-Guided Prediction Approach for Assessing the Risks of Drug-Drug Interactions Associated with Circulating Inhibitory Metabolites
      Zhe-Yi Hu, Robert B. Parker and S. Casey Laizure
      Drug Metabolism and Disposition August 2012, 40 (8) 1487-1494; DOI: https://doi.org/10.1124/dmd.112.045799

I

  1. Ismair, Manfred

    1. The Development, Characterization, and Application of an OATP1B1 Inhibition Assay in Drug Discovery
      Matthew G. Soars, Patrick Barton, Manfred Ismair, Rachael Jupp and Robert J. Riley
      Drug Metabolism and Disposition August 2012, 40 (8) 1641-1648; DOI: https://doi.org/10.1124/dmd.111.042382

J

  1. Jang, Young Pyo

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  2. Jiang, Ying

    1. Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide
      Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang and Ping Kang
      Drug Metabolism and Disposition August 2012, 40 (8) 1575-1587; DOI: https://doi.org/10.1124/dmd.112.045823

  3. Jiang, Zhi-Hong

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

  4. Jigorel, Emilie

    1. Utility of Drug Depletion-Time Profiles in Isolated Hepatocytes for Accessing Hepatic Uptake Clearance: Identifying Rate-Limiting Steps and Role of Passive Processes
      Emilie Jigorel and J. Brian Houston
      Drug Metabolism and Disposition August 2012, 40 (8) 1596-1602; DOI: https://doi.org/10.1124/dmd.112.045732

  5. Jupp, Rachael

    1. The Development, Characterization, and Application of an OATP1B1 Inhibition Assay in Drug Discovery
      Matthew G. Soars, Patrick Barton, Manfred Ismair, Rachael Jupp and Robert J. Riley
      Drug Metabolism and Disposition August 2012, 40 (8) 1641-1648; DOI: https://doi.org/10.1124/dmd.111.042382

K

  1. Kadlubar, Susan A.

    1. Potent Inhibition of Human Sulfotransferase 1A1 by 17α-Ethinylestradiol: Role of 3′-Phosphoadenosine 5′-Phosphosulfate Binding and Structural Rearrangements in Regulating Inhibition and Activity
      Katie Jo Rohn, Ian T. Cook, Thomas S. Leyh, Susan A. Kadlubar and Charles N. Falany
      Drug Metabolism and Disposition August 2012, 40 (8) 1588-1595; DOI: https://doi.org/10.1124/dmd.112.045583

  2. Kang, Jaw-Jou

    1. Metabolism of (2S)-Pterosin A: Identification of the Phase I and Phase II Metabolites in Rat Urine
      Yung-Ping Lee, Feng-Lin Hsu, Jaw-Jou Kang, Chien-Kuang Chen and Shoei-Sheng Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.045039

  3. Kang, Ping

    1. Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide
      Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang and Ping Kang
      Drug Metabolism and Disposition August 2012, 40 (8) 1575-1587; DOI: https://doi.org/10.1124/dmd.112.045823

  4. Kim, Han Gyul

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  5. Krämer, Stefanie D.

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443

L

  1. Lai, Yurong

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  2. Laizure, S. Casey

    1. In Vivo Information-Guided Prediction Approach for Assessing the Risks of Drug-Drug Interactions Associated with Circulating Inhibitory Metabolites
      Zhe-Yi Hu, Robert B. Parker and S. Casey Laizure
      Drug Metabolism and Disposition August 2012, 40 (8) 1487-1494; DOI: https://doi.org/10.1124/dmd.112.045799

  3. Lazic, Stanley E.

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443
    2. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  4. Lee, Joo Hyun

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  5. Lee, Seung Jae

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  6. Lee, Shoei-Sheng

    1. Metabolism of (2S)-Pterosin A: Identification of the Phase I and Phase II Metabolites in Rat Urine
      Yung-Ping Lee, Feng-Lin Hsu, Jaw-Jou Kang, Chien-Kuang Chen and Shoei-Sheng Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.045039

  7. Lee, Young-Joo

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  8. Lee, Yung-Ping

    1. Metabolism of (2S)-Pterosin A: Identification of the Phase I and Phase II Metabolites in Rat Urine
      Yung-Ping Lee, Feng-Lin Hsu, Jaw-Jou Kang, Chien-Kuang Chen and Shoei-Sheng Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.045039

  9. Lenz, Eva M.

    1. Reaction of Homopiperazine with Endogenous Formaldehyde: A Carbon Hydrogen Addition Metabolite/Product Identified in Rat Urine and Blood
      Scott Martin, Eva M. Lenz, Dave Temesi, Martin Wild and Malcolm R. Clench
      Drug Metabolism and Disposition August 2012, 40 (8) 1478-1486; DOI: https://doi.org/10.1124/dmd.112.044917

  10. Leyh, Thomas S.

    1. Potent Inhibition of Human Sulfotransferase 1A1 by 17α-Ethinylestradiol: Role of 3′-Phosphoadenosine 5′-Phosphosulfate Binding and Structural Rearrangements in Regulating Inhibition and Activity
      Katie Jo Rohn, Ian T. Cook, Thomas S. Leyh, Susan A. Kadlubar and Charles N. Falany
      Drug Metabolism and Disposition August 2012, 40 (8) 1588-1595; DOI: https://doi.org/10.1124/dmd.112.045583

  11. Litchfield, John

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  12. Lu, Jirong

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

  13. Luo, Shuhua

    1. Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
      Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
      Drug Metabolism and Disposition August 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245

M

  1. Martin, Scott

    1. Reaction of Homopiperazine with Endogenous Formaldehyde: A Carbon Hydrogen Addition Metabolite/Product Identified in Rat Urine and Blood
      Scott Martin, Eva M. Lenz, Dave Temesi, Martin Wild and Malcolm R. Clench
      Drug Metabolism and Disposition August 2012, 40 (8) 1478-1486; DOI: https://doi.org/10.1124/dmd.112.044917

N

  1. Nakajima, Miki

    1. Preparation of a Specific Monoclonal Antibody against Human UDP-Glucuronosyltransferase (UGT) 1A9 and Evaluation of UGT1A9 Protein Levels in Human Tissues
      Shingo Oda, Miki Nakajima, Masahiko Hatakeyama, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition August 2012, 40 (8) 1620-1627; DOI: https://doi.org/10.1124/dmd.112.045625

  2. Nelson, Sidney D.

    1. Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the meta-Isomer of Acetaminophen
      John P. Harrelson, Brendan D. Stamper, John D. Chapman, David R. Goodlett and Sidney D. Nelson
      Drug Metabolism and Disposition August 2012, 40 (8) 1460-1465; DOI: https://doi.org/10.1124/dmd.112.045492

  3. Nicolas, J.-M.

    1. Effect of Gemfibrozil on the Metabolism of Brivaracetam In Vitro and in Human Subjects
      J.-M. Nicolas, H. Chanteux, M. Rosa, S. Watanabe and A. Stockis
      Drug Metabolism and Disposition August 2012, 40 (8) 1466-1472; DOI: https://doi.org/10.1124/dmd.112.045328

  4. Niu, Tao

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

O

  1. Oda, Shingo

    1. Preparation of a Specific Monoclonal Antibody against Human UDP-Glucuronosyltransferase (UGT) 1A9 and Evaluation of UGT1A9 Protein Levels in Human Tissues
      Shingo Oda, Miki Nakajima, Masahiko Hatakeyama, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition August 2012, 40 (8) 1620-1627; DOI: https://doi.org/10.1124/dmd.112.045625

  2. Oh, Ju-Hee

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  3. Ohe, Tomoyuki

    1. A Novel Method for the Determination of the Site of Glucuronidation by Ion Mobility Spectrometry-Mass Spectrometry
      Atsushi Shimizu, Tomoyuki Ohe and Masato Chiba
      Drug Metabolism and Disposition August 2012, 40 (8) 1456-1459; DOI: https://doi.org/10.1124/dmd.112.045435

  4. Otteneder, Michael B.

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

P

  1. Parker, Robert B.

    1. In Vivo Information-Guided Prediction Approach for Assessing the Risks of Drug-Drug Interactions Associated with Circulating Inhibitory Metabolites
      Zhe-Yi Hu, Robert B. Parker and S. Casey Laizure
      Drug Metabolism and Disposition August 2012, 40 (8) 1487-1494; DOI: https://doi.org/10.1124/dmd.112.045799

  2. Parrott, Neil J.

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443

  3. Peters, Sheila Annie

    1. Evaluation of the Use of Static and Dynamic Models to Predict Drug-Drug Interaction and Its Associated Variability: Impact on Drug Discovery and Early Development
      Sheila Annie Peters, Patricia E. Schroeder, Nagdeep Giri and Hugues Dolgos
      Drug Metabolism and Disposition August 2012, 40 (8) 1495-1507; DOI: https://doi.org/10.1124/dmd.112.044602

  4. Poirier, Agnès

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  5. Portmann, Renée

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  6. Prinssen, Eric

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

R

  1. Rayner, Craig R.

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  2. Riley, Robert J.

    1. The Development, Characterization, and Application of an OATP1B1 Inhibition Assay in Drug Discovery
      Matthew G. Soars, Patrick Barton, Manfred Ismair, Rachael Jupp and Robert J. Riley
      Drug Metabolism and Disposition August 2012, 40 (8) 1641-1648; DOI: https://doi.org/10.1124/dmd.111.042382

  3. Rohn, Katie Jo

    1. Potent Inhibition of Human Sulfotransferase 1A1 by 17α-Ethinylestradiol: Role of 3′-Phosphoadenosine 5′-Phosphosulfate Binding and Structural Rearrangements in Regulating Inhibition and Activity
      Katie Jo Rohn, Ian T. Cook, Thomas S. Leyh, Susan A. Kadlubar and Charles N. Falany
      Drug Metabolism and Disposition August 2012, 40 (8) 1588-1595; DOI: https://doi.org/10.1124/dmd.112.045583

  4. Rosa, M.

    1. Effect of Gemfibrozil on the Metabolism of Brivaracetam In Vitro and in Human Subjects
      J.-M. Nicolas, H. Chanteux, M. Rosa, S. Watanabe and A. Stockis
      Drug Metabolism and Disposition August 2012, 40 (8) 1466-1472; DOI: https://doi.org/10.1124/dmd.112.045328

S

  1. Sane, Ramola

    1. Brain Distribution and Bioavailability of Elacridar after Different Routes of Administration in the Mouse
      Ramola Sane, Sagar Agarwal and William F. Elmquist
      Drug Metabolism and Disposition August 2012, 40 (8) 1612-1619; DOI: https://doi.org/10.1124/dmd.112.045930

  2. Schroeder, Patricia E.

    1. Evaluation of the Use of Static and Dynamic Models to Predict Drug-Drug Interaction and Its Associated Variability: Impact on Drug Discovery and Early Development
      Sheila Annie Peters, Patricia E. Schroeder, Nagdeep Giri and Hugues Dolgos
      Drug Metabolism and Disposition August 2012, 40 (8) 1495-1507; DOI: https://doi.org/10.1124/dmd.112.044602

  3. Schuler, Franz

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443
    2. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  4. Shimizu, Atsushi

    1. A Novel Method for the Determination of the Site of Glucuronidation by Ion Mobility Spectrometry-Mass Spectrometry
      Atsushi Shimizu, Tomoyuki Ohe and Masato Chiba
      Drug Metabolism and Disposition August 2012, 40 (8) 1456-1459; DOI: https://doi.org/10.1124/dmd.112.045435

  5. Shin, Eunji

    1. The Increased Cellular Uptake and Biliary Excretion of Curcumin by Quercetin: A Possible Role of Albumin Binding Interaction
      Han Gyul Kim, Joo Hyun Lee, Seung Jae Lee, Ju-Hee Oh, Eunji Shin, Young Pyo Jang and Young-Joo Lee
      Drug Metabolism and Disposition August 2012, 40 (8) 1452-1455; DOI: https://doi.org/10.1124/dmd.111.044123

  6. Singer, Thomas

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  7. Smith, David E.

    1. Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies
      Agnès Poirier, Sara Belli, Christoph Funk, Michael B. Otteneder, Renée Portmann, Katja Heinig, Eric Prinssen, Stanley E. Lazic, Craig R. Rayner, Gerhard Hoffmann, Thomas Singer, David E. Smith and Franz Schuler
      Drug Metabolism and Disposition August 2012, 40 (8) 1556-1565; DOI: https://doi.org/10.1124/dmd.112.044990

  8. Soars, Matthew G.

    1. The Development, Characterization, and Application of an OATP1B1 Inhibition Assay in Drug Discovery
      Matthew G. Soars, Patrick Barton, Manfred Ismair, Rachael Jupp and Robert J. Riley
      Drug Metabolism and Disposition August 2012, 40 (8) 1641-1648; DOI: https://doi.org/10.1124/dmd.111.042382

  9. Stamper, Brendan D.

    1. Covalent Modification and Time-Dependent Inhibition of Human CYP2E1 by the meta-Isomer of Acetaminophen
      John P. Harrelson, Brendan D. Stamper, John D. Chapman, David R. Goodlett and Sidney D. Nelson
      Drug Metabolism and Disposition August 2012, 40 (8) 1460-1465; DOI: https://doi.org/10.1124/dmd.112.045492

  10. Steiner, Guido

    1. Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs
      Stephanie Haller, Franz Schuler, Stanley E. Lazic, Dalila Bachir-Cherif, Stefanie D. Krämer, Neil J. Parrott, Guido Steiner and Sara Belli
      Drug Metabolism and Disposition August 2012, 40 (8) 1603-1611; DOI: https://doi.org/10.1124/dmd.112.045443

  11. Stockis, A.

    1. Effect of Gemfibrozil on the Metabolism of Brivaracetam In Vitro and in Human Subjects
      J.-M. Nicolas, H. Chanteux, M. Rosa, S. Watanabe and A. Stockis
      Drug Metabolism and Disposition August 2012, 40 (8) 1466-1472; DOI: https://doi.org/10.1124/dmd.112.045328

  12. Sun, Hao

    1. Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide
      Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang and Ping Kang
      Drug Metabolism and Disposition August 2012, 40 (8) 1575-1587; DOI: https://doi.org/10.1124/dmd.112.045823

T

  1. Tadano Lohr, Michelle

    1. Metabolic Activation of Mefenamic Acid Leading to Mefenamyl-S-Acyl-Glutathione Adduct Formation In Vitro and In Vivo in Rat
      Mark P. Grillo, Michelle Tadano Lohr and Jill C. M. Wait
      Drug Metabolism and Disposition August 2012, 40 (8) 1515-1526; DOI: https://doi.org/10.1124/dmd.112.046102

  2. Temesi, Dave

    1. Reaction of Homopiperazine with Endogenous Formaldehyde: A Carbon Hydrogen Addition Metabolite/Product Identified in Rat Urine and Blood
      Scott Martin, Eva M. Lenz, Dave Temesi, Martin Wild and Malcolm R. Clench
      Drug Metabolism and Disposition August 2012, 40 (8) 1478-1486; DOI: https://doi.org/10.1124/dmd.112.044917

U

  1. Urquhart, Bradley L.

    1. Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
      Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
      Drug Metabolism and Disposition August 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245

V

  1. Varma, Manthena V. S.

    1. Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion
      Manthena V. S. Varma, George Chang, Yurong Lai, Bo Feng, Ayman F. El-Kattan, John Litchfield and Theunis C. Goosen
      Drug Metabolism and Disposition August 2012, 40 (8) 1527-1537; DOI: https://doi.org/10.1124/dmd.112.044628

  2. Velenosi, Thomas J.

    1. Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
      Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
      Drug Metabolism and Disposition August 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245

W

  1. Wait, Jill C. M.

    1. Metabolic Activation of Mefenamic Acid Leading to Mefenamyl-S-Acyl-Glutathione Adduct Formation In Vitro and In Vivo in Rat
      Mark P. Grillo, Michelle Tadano Lohr and Jill C. M. Wait
      Drug Metabolism and Disposition August 2012, 40 (8) 1515-1526; DOI: https://doi.org/10.1124/dmd.112.046102

  2. Wang, Hao

    1. Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
      Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
      Drug Metabolism and Disposition August 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245

  3. Wang, Jing-Rong

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

  4. Watanabe, S.

    1. Effect of Gemfibrozil on the Metabolism of Brivaracetam In Vitro and in Human Subjects
      J.-M. Nicolas, H. Chanteux, M. Rosa, S. Watanabe and A. Stockis
      Drug Metabolism and Disposition August 2012, 40 (8) 1466-1472; DOI: https://doi.org/10.1124/dmd.112.045328

  5. Wild, Martin

    1. Reaction of Homopiperazine with Endogenous Formaldehyde: A Carbon Hydrogen Addition Metabolite/Product Identified in Rat Urine and Blood
      Scott Martin, Eva M. Lenz, Dave Temesi, Martin Wild and Malcolm R. Clench
      Drug Metabolism and Disposition August 2012, 40 (8) 1478-1486; DOI: https://doi.org/10.1124/dmd.112.044917

  6. Witcher, Derrick R.

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

  7. Wroblewski, Victor J.

    1. FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
      Amita Datta-Mannan, Chi-Kin Chow, Craig Dickinson, David Driver, Jirong Lu, Derrick R. Witcher and Victor J. Wroblewski
      Drug Metabolism and Disposition August 2012, 40 (8) 1545-1555; DOI: https://doi.org/10.1124/dmd.112.045864

X

  1. Xiang, Cathie

    1. Effect of Structural Variation on Aldehyde Oxidase-Catalyzed Oxidation of Zoniporide
      Deepak Dalvie, Hao Sun, Cathie Xiang, Qiyue Hu, Ying Jiang and Ping Kang
      Drug Metabolism and Disposition August 2012, 40 (8) 1575-1587; DOI: https://doi.org/10.1124/dmd.112.045823

  2. Xie, Cen

    1. Identification of the ortho-Benzoquinone Intermediate of 5-O-Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations
      Cen Xie, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2012, 40 (8) 1628-1640; DOI: https://doi.org/10.1124/dmd.112.045641

Y

  1. Yang, Zhen

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

  2. Yin, Taijun

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

  3. Yokoi, Tsuyoshi

    1. Preparation of a Specific Monoclonal Antibody against Human UDP-Glucuronosyltransferase (UGT) 1A9 and Evaluation of UGT1A9 Protein Levels in Human Tissues
      Shingo Oda, Miki Nakajima, Masahiko Hatakeyama, Tatsuki Fukami and Tsuyoshi Yokoi
      Drug Metabolism and Disposition August 2012, 40 (8) 1620-1627; DOI: https://doi.org/10.1124/dmd.112.045625

  4. You, Ming

    1. Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora
      Zhen Yang, Jing-Rong Wang, Tao Niu, Song Gao, Taijun Yin, Ming You, Zhi-Hong Jiang and Ming Hu
      Drug Metabolism and Disposition August 2012, 40 (8) 1538-1544; DOI: https://doi.org/10.1124/dmd.111.044008

Z

  1. Zhong, Dafang

    1. Identification of the ortho-Benzoquinone Intermediate of 5-O-Caffeoylquinic Acid In Vitro and In Vivo: Comparison of Bioactivation under Normal and Pathological Situations
      Cen Xie, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition August 2012, 40 (8) 1628-1640; DOI: https://doi.org/10.1124/dmd.112.045641
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