Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease

Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
Drug Metabolism and Disposition August 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245
Thomas J. Velenosi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Angel Y. N. Fu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shuhua Luo
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hao Wang
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bradley L. Urquhart
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Information

vol. 40 no. 8 1508-1514
DOI 
https://doi.org/10.1124/dmd.112.045245
PubMed 
22573661

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 29, 2012
  • Accepted May 9, 2012
  • Published online July 17, 2012.

Article Versions

  • Earlier version (May 9, 2012 - 10:15).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Thomas J. Velenosi,
  2. Angel Y. N. Fu,
  3. Shuhua Luo,
  4. Hao Wang and
  5. Bradley L. Urquhart
  1. Departments of Physiology and Pharmacology (T.J.V., A.Y.N.F., B.L.U.) and Surgery (S.L., H.W.), Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, Canada; and Divisions of Clinical Pharmacology and Nephrology, Department of Medicine, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, Canada (B.L.U.)
  1. Address correspondence to:
    Dr. Bradley L. Urquhart, 1151 Richmond Street, Medical Sciences Building, Room 216, London, Ontario, Canada N6A 5C1. E-mail: brad.urquhart{at}schulich.uwo.ca
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: May 2012 to June 2022

AbstractFullPdf
May 2012379296
Jun 201263028
Jul 20124351453
Aug 20123132135
Sep 20121431029
Oct 2012931430
Nov 2012832017
Dec 20126069
Jan 2013871928
Feb 2013881120
Mar 2013531224
Apr 201332915
May 2013241112
Jun 2013241213
Jul 20132177
Aug 2013271310
Sep 2013582018
Oct 2013379611
Nov 2013411631
Dec 201319622
Jan 2014152321
Feb 2014171814
Mar 2014213319
Apr 2014241914
May 201412812
Jun 2014331712
Jul 2014332310
Aug 20142078
Sep 2014221813
Oct 2014161313
Nov 2014232215
Dec 20144138
Jan 201519148
Feb 2015191613
Mar 2015251415
Apr 2015231616
May 20151899
Jun 20152096
Jul 2015363814
Aug 201514138
Sep 201523206
Oct 201527159
Nov 2015212917
Dec 20152599
Jan 2016221820
Feb 2016141317
Mar 201692329
Apr 2016131610
May 2016553
Jun 2016171036
Jul 201691019
Aug 2016262119
Sep 2016162527
Oct 20163208
Nov 20161217
Dec 201603019
Jan 201701616
Feb 201712119
Mar 201702214
Apr 201702722
May 201713020
Jun 201701616
Jul 201771115
Aug 20173137
Sep 20176159
Oct 20173179
Nov 201792521
Dec 20172206
Jan 201852813
Feb 20183188
Mar 201822615
Apr 20181258
May 20182168
Jun 20180176
Jul 201831115
Aug 20181147
Sep 201802511
Oct 201811215
Nov 20180168
Dec 20182451
Jan 201914310
Feb 20192449
Mar 20192156
Apr 20192535
May 20191155
Jun 20191024
Jul 20191813
Aug 20191232
Sep 20191424
Oct 201932510
Nov 20192532
Dec 20192776
Jan 20203325
Feb 20201333
Mar 20201312
Apr 2020833
May 2020955
Jun 2020454
Jul 2020752
Aug 2020032
Sep 20202713
Oct 2020723
Nov 20201353
Dec 20201912
Jan 202116105
Feb 20212796
Mar 20212110
Apr 20212312
May 20212150
Jun 20212132
Jul 20212155
Aug 20212773
Sep 20211962
Oct 20212668
Nov 20212727
Dec 20212023
Jan 20221434
Feb 20221041
Mar 20221075
Apr 20221154
May 20221922
Jun 20222132

PreviousNext
Back to top

In this issue

Drug Metabolism and Disposition: 40 (8)
Drug Metabolism and Disposition
Vol. 40, Issue 8
1 Aug 2012
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Down-Regulation of Hepatic CYP3A and CYP2C Mediated Metabolism in Rats with Moderate Chronic Kidney Disease
(Your Name) has forwarded a page to you from Drug Metabolism & Disposition
(Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

DRUG METABOLISM IN CKD

Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
Drug Metabolism and Disposition August 1, 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

DRUG METABOLISM IN CKD

Thomas J. Velenosi, Angel Y. N. Fu, Shuhua Luo, Hao Wang and Bradley L. Urquhart
Drug Metabolism and Disposition August 1, 2012, 40 (8) 1508-1514; DOI: https://doi.org/10.1124/dmd.112.045245
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Authorship Contributions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • TMDD Affects PK of IL-10 Fc-Fusion Proteins
  • In Vitro Models to Study P-gp-Mediated Intestinal DDIs
  • Covalent Inactivation of CYP3A by Futibatinib
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2022 by the American Society for Pharmacology and Experimental Therapeutics