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Utility of Drug Depletion-Time Profiles in Isolated Hepatocytes for Accessing Hepatic Uptake Clearance: Identifying Rate-Limiting Steps and Role of Passive Processes

Emilie Jigorel and J. Brian Houston
Drug Metabolism and Disposition August 2012, 40 (8) 1596-1602; DOI: https://doi.org/10.1124/dmd.112.045732
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Research ArticleArticle

DRUG DEPLETION AND HEPATIC UPTAKE CLEARANCE

Emilie Jigorel and J. Brian Houston
Drug Metabolism and Disposition August 1, 2012, 40 (8) 1596-1602; DOI: https://doi.org/10.1124/dmd.112.045732
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