Index by author
September 01, 2012; Volume 40,Issue 9
A
Adams, Christopher M.
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
Amunugama, Hemali T.
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by Methadone through Destruction of Prosthetic HemeHemali T. Amunugama, Haoming Zhang and Paul F. HollenbergDrug Metabolism and Disposition September 2012, 40 (9) 1765-1770; DOI: https://doi.org/10.1124/dmd.112.045971
Arora, Vinod K.
- You have accessA Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde OxidaseVinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong ShuDrug Metabolism and Disposition September 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545
Atkinson, Karen
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
B
Bakken, Gry Vibeke
- You have accessMetabolism of the Active Metabolite of Quetiapine, N-Desalkylquetiapine In VitroGry Vibeke Bakken, Espen Molden, Karoline Knutsen, Niclas Lunder and Monica HermannDrug Metabolism and Disposition September 2012, 40 (9) 1778-1784; DOI: https://doi.org/10.1124/dmd.112.045237
Bao, Jing Q.
- You have accessCharacterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein PharmacokineticsMaciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William HigginsDrug Metabolism and Disposition September 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508
Bates, Brittney S.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Bedwell, David W.
- You have accessCharacterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein PharmacokineticsMaciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William HigginsDrug Metabolism and Disposition September 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508
Bi, Yi-An
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
Blobaum, Anna L.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Bonacorsi, Samuel
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Bratton, Stacie M.
- You have accessRole of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10Barbara Fedejko-Kap, Stacie M. Bratton, Moshe Finel, Anna Radominska-Pandya and Zofia MazerskaDrug Metabolism and Disposition September 2012, 40 (9) 1736-1743; DOI: https://doi.org/10.1124/dmd.112.045401
Brewer, Katrina A.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Bridges, Thomas M.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Burt, Howard J.
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
Byers, Frank W.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
C
Cameron, Michael D.
- You have accessDiscovery of a Highly Selective CYP3A4 Inhibitor Suitable for Reaction Phenotyping Studies and Differentiation of CYP3A4 and CYP3A5Xiaohai Li, Xinyi Song, Theodore M. Kamenecka and Michael D. CameronDrug Metabolism and Disposition September 2012, 40 (9) 1803-1809; DOI: https://doi.org/10.1124/dmd.112.046144
Canet, Mark J.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Cao, Kai
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Chang, Shu-Ying
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Chen, Cliff
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Cherrington, Nathan J.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Chimalakonda, Anjaneya
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Chin, Christina
- You have accessExcretion and Metabolism of Milnacipran in Humans after Oral Administration of Milnacipran HydrochlorideFanying Li, Christina Chin, Julie Wangsa and John HoDrug Metabolism and Disposition September 2012, 40 (9) 1723-1735; DOI: https://doi.org/10.1124/dmd.112.045120
Collins, Claire
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
Conn, P. Jeffrey
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Corlew, Melany M.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
D
Dain, Jeremy
- You have accessMetabolism and Pharmacokinetics of Indacaterol in HumansMark Kagan, Jeremy Dain, Lana Peng and Christine ReynoldsDrug Metabolism and Disposition September 2012, 40 (9) 1712-1722; DOI: https://doi.org/10.1124/dmd.112.046151
Daniels, J. Scott
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Di, Li
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
E
Emanuel, Stuart L.
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Emmitte, Kyle A.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
F
Fedejko-Kap, Barbara
- You have accessRole of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10Barbara Fedejko-Kap, Stacie M. Bratton, Moshe Finel, Anna Radominska-Pandya and Zofia MazerskaDrug Metabolism and Disposition September 2012, 40 (9) 1736-1743; DOI: https://doi.org/10.1124/dmd.112.045401
Felts, Andrew S.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Finel, Moshe
- You have accessRole of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10Barbara Fedejko-Kap, Stacie M. Bratton, Moshe Finel, Anna Radominska-Pandya and Zofia MazerskaDrug Metabolism and Disposition September 2012, 40 (9) 1736-1743; DOI: https://doi.org/10.1124/dmd.112.045401
Fitch, William L.
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
Fujioka, Yasushi
- You have accessRisk Assessment of Mechanism-Based Inactivation in Drug-Drug InteractionsYasushi Fujioka, Kent L. Kunze and Nina IsoherranenDrug Metabolism and Disposition September 2012, 40 (9) 1653-1657; DOI: https://doi.org/10.1124/dmd.112.046649
Furukawa, Takako
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
G
Galetin, Aleksandra
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
- You have accessUse of Mechanistic Modeling to Assess Interindividual Variability and Interspecies Differences in Active Uptake in Human and Rat HepatocytesKarelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1744-1756; DOI: https://doi.org/10.1124/dmd.112.046193
Gandolfi, A. Jay
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Geoghegan, Kieran F.
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Goodlett, David R.
- You have accessEvaluation of P450 Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human HepatocytesJie Xing, Brian J. Kirby, Dale Whittington, Yakun Wan and David R. GoodlettDrug Metabolism and Disposition September 2012, 40 (9) 1757-1764; DOI: https://doi.org/10.1124/dmd.112.045765
Goosen, Theunis C.
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
H
Hagihara, Katsunobu
- You have accessGlutaredoxin Is Involved in the Formation of the Pharmacologically Active Metabolite of Clopidogrel from Its GSH ConjugateKatsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Toshihiko Ikeda and Takashi IzumiDrug Metabolism and Disposition September 2012, 40 (9) 1854-1859; DOI: https://doi.org/10.1124/dmd.112.045914
Hardwick, Rhiannon N.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Helal, Christopher J.
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Hermann, Monica
- You have accessMetabolism of the Active Metabolite of Quetiapine, N-Desalkylquetiapine In VitroGry Vibeke Bakken, Espen Molden, Karoline Knutsen, Niclas Lunder and Monica HermannDrug Metabolism and Disposition September 2012, 40 (9) 1778-1784; DOI: https://doi.org/10.1124/dmd.112.045237
Higgins, J. William
- You have accessCharacterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein PharmacokineticsMaciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William HigginsDrug Metabolism and Disposition September 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508
Ho, John
- You have accessExcretion and Metabolism of Milnacipran in Humans after Oral Administration of Milnacipran HydrochlorideFanying Li, Christina Chin, Julie Wangsa and John HoDrug Metabolism and Disposition September 2012, 40 (9) 1723-1735; DOI: https://doi.org/10.1124/dmd.112.045120
Hollenberg, Paul F.
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by Methadone through Destruction of Prosthetic HemeHemali T. Amunugama, Haoming Zhang and Paul F. HollenbergDrug Metabolism and Disposition September 2012, 40 (9) 1765-1770; DOI: https://doi.org/10.1124/dmd.112.045971
Hosbach, Jennifer
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Hosoya, Ken-ichi
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Houston, J. Brian
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
- You have accessUse of Mechanistic Modeling to Assess Interindividual Variability and Interspecies Differences in Active Uptake in Human and Rat HepatocytesKarelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1744-1756; DOI: https://doi.org/10.1124/dmd.112.046193
Huang, Stella
- You have accessA Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde OxidaseVinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong ShuDrug Metabolism and Disposition September 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545
Hurley, Jeremy
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Hyland, Ruth
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
I
Ikeda, Toshihiko
- You have accessGlutaredoxin Is Involved in the Formation of the Pharmacologically Active Metabolite of Clopidogrel from Its GSH ConjugateKatsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Toshihiko Ikeda and Takashi IzumiDrug Metabolism and Disposition September 2012, 40 (9) 1854-1859; DOI: https://doi.org/10.1124/dmd.112.045914
Isoherranen, Nina
- You have accessRisk Assessment of Mechanism-Based Inactivation in Drug-Drug InteractionsYasushi Fujioka, Kent L. Kunze and Nina IsoherranenDrug Metabolism and Disposition September 2012, 40 (9) 1653-1657; DOI: https://doi.org/10.1124/dmd.112.046649
Izumi, Takashi
- You have accessGlutaredoxin Is Involved in the Formation of the Pharmacologically Active Metabolite of Clopidogrel from Its GSH ConjugateKatsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Toshihiko Ikeda and Takashi IzumiDrug Metabolism and Disposition September 2012, 40 (9) 1854-1859; DOI: https://doi.org/10.1124/dmd.112.045914
J
Jones, Carrie K.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
K
Kadono, Keitaro
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Kagan, Mark
- You have accessMetabolism and Pharmacokinetics of Indacaterol in HumansMark Kagan, Jeremy Dain, Lana Peng and Christine ReynoldsDrug Metabolism and Disposition September 2012, 40 (9) 1712-1722; DOI: https://doi.org/10.1124/dmd.112.046151
Kamenecka, Theodore M.
- You have accessDiscovery of a Highly Selective CYP3A4 Inhibitor Suitable for Reaction Phenotyping Studies and Differentiation of CYP3A4 and CYP3A5Xiaohai Li, Xinyi Song, Theodore M. Kamenecka and Michael D. CameronDrug Metabolism and Disposition September 2012, 40 (9) 1803-1809; DOI: https://doi.org/10.1124/dmd.112.046144
Kang, Ping
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Kazui, Miho
- You have accessGlutaredoxin Is Involved in the Formation of the Pharmacologically Active Metabolite of Clopidogrel from Its GSH ConjugateKatsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Toshihiko Ikeda and Takashi IzumiDrug Metabolism and Disposition September 2012, 40 (9) 1854-1859; DOI: https://doi.org/10.1124/dmd.112.045914
Kenworthy, Kathryn E.
- You have accessUse of Mechanistic Modeling to Assess Interindividual Variability and Interspecies Differences in Active Uptake in Human and Rat HepatocytesKarelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1744-1756; DOI: https://doi.org/10.1124/dmd.112.046193
Kirby, Brian J.
- You have accessEvaluation of P450 Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human HepatocytesJie Xing, Brian J. Kirby, Dale Whittington, Yakun Wan and David R. GoodlettDrug Metabolism and Disposition September 2012, 40 (9) 1757-1764; DOI: https://doi.org/10.1124/dmd.112.045765
Klimecki, Walter T.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Knutsen, Karoline
- You have accessMetabolism of the Active Metabolite of Quetiapine, N-Desalkylquetiapine In VitroGry Vibeke Bakken, Espen Molden, Karoline Knutsen, Niclas Lunder and Monica HermannDrug Metabolism and Disposition September 2012, 40 (9) 1778-1784; DOI: https://doi.org/10.1124/dmd.112.045237
Kopplin, Michael J.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Korzekwa, Ken
- You have accessCommentary: Nonspecific Protein Binding versus Membrane Partitioning: It Is Not Just SemanticsSwati Nagar and Ken KorzekwaDrug Metabolism and Disposition September 2012, 40 (9) 1649-1652; DOI: https://doi.org/10.1124/dmd.112.046599
Kunze, Kent L.
- You have accessRisk Assessment of Mechanism-Based Inactivation in Drug-Drug InteractionsYasushi Fujioka, Kent L. Kunze and Nina IsoherranenDrug Metabolism and Disposition September 2012, 40 (9) 1653-1657; DOI: https://doi.org/10.1124/dmd.112.046649
Kurihara, Atsushi
- You have accessGlutaredoxin Is Involved in the Formation of the Pharmacologically Active Metabolite of Clopidogrel from Its GSH ConjugateKatsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Toshihiko Ikeda and Takashi IzumiDrug Metabolism and Disposition September 2012, 40 (9) 1854-1859; DOI: https://doi.org/10.1124/dmd.112.045914
L
Lai, Yurong
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
Lake, April D.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Lee, Leslie B.
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Li, Fanying
- You have accessExcretion and Metabolism of Milnacipran in Humans after Oral Administration of Milnacipran HydrochlorideFanying Li, Christina Chin, Julie Wangsa and John HoDrug Metabolism and Disposition September 2012, 40 (9) 1723-1735; DOI: https://doi.org/10.1124/dmd.112.045120
Li, Xiaohai
- You have accessDiscovery of a Highly Selective CYP3A4 Inhibitor Suitable for Reaction Phenotyping Studies and Differentiation of CYP3A4 and CYP3A5Xiaohai Li, Xinyi Song, Theodore M. Kamenecka and Michael D. CameronDrug Metabolism and Disposition September 2012, 40 (9) 1803-1809; DOI: https://doi.org/10.1124/dmd.112.046144
Lin, Zheng
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Lindsley, Craig W.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Lunder, Niclas
- You have accessMetabolism of the Active Metabolite of Quetiapine, N-Desalkylquetiapine In VitroGry Vibeke Bakken, Espen Molden, Karoline Knutsen, Niclas Lunder and Monica HermannDrug Metabolism and Disposition September 2012, 40 (9) 1778-1784; DOI: https://doi.org/10.1124/dmd.112.045237
Luo, Gang
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
M
Manka, Jason
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Marini, Joseph
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
Mazerska, Zofia
- You have accessRole of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10Barbara Fedejko-Kap, Stacie M. Bratton, Moshe Finel, Anna Radominska-Pandya and Zofia MazerskaDrug Metabolism and Disposition September 2012, 40 (9) 1736-1743; DOI: https://doi.org/10.1124/dmd.112.045401
McDonald, Thomas S.
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
Ménochet, Karelle
- You have accessUse of Mechanistic Modeling to Assess Interindividual Variability and Interspecies Differences in Active Uptake in Human and Rat HepatocytesKarelle Ménochet, Kathryn E. Kenworthy, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1744-1756; DOI: https://doi.org/10.1124/dmd.112.046193
Molden, Espen
- You have accessMetabolism of the Active Metabolite of Quetiapine, N-Desalkylquetiapine In VitroGry Vibeke Bakken, Espen Molden, Karoline Knutsen, Niclas Lunder and Monica HermannDrug Metabolism and Disposition September 2012, 40 (9) 1778-1784; DOI: https://doi.org/10.1124/dmd.112.045237
Moriguchi, Hiroyuki
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Morin, Paul
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Morrison, Ryan D.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Musick, Timothy
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
N
Nagar, Swati
- You have accessCommentary: Nonspecific Protein Binding versus Membrane Partitioning: It Is Not Just SemanticsSwati Nagar and Ken KorzekwaDrug Metabolism and Disposition September 2012, 40 (9) 1649-1652; DOI: https://doi.org/10.1124/dmd.112.046599
Nakamori, Fumihiro
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Naritomi, Yoichi
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Niswender, Colleen M.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
O
Obach, R. Scott
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Olivero, Alan G.
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Oronsky, Bryan
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
P
Padowski, Jeannie M.
- You have accessInfluence of Enterohepatic Recycling on the Time Course of Brain-to-Blood Partitioning of Valproic Acid in RatsJeannie M. Padowski and Gary M. PollackDrug Metabolism and Disposition September 2012, 40 (9) 1846-1853; DOI: https://doi.org/10.1124/dmd.112.045500
Pang, Jodie
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Peng, Lana
- You have accessMetabolism and Pharmacokinetics of Indacaterol in HumansMark Kagan, Jeremy Dain, Lana Peng and Christine ReynoldsDrug Metabolism and Disposition September 2012, 40 (9) 1712-1722; DOI: https://doi.org/10.1124/dmd.112.046151
Pertinez, Henry
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
Philip, Thomas
- You have accessA Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde OxidaseVinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong ShuDrug Metabolism and Disposition September 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545
Plise, Emile G.
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Pollack, Gary M.
- You have accessInfluence of Enterohepatic Recycling on the Time Course of Brain-to-Blood Partitioning of Valproic Acid in RatsJeannie M. Padowski and Gary M. PollackDrug Metabolism and Disposition September 2012, 40 (9) 1846-1853; DOI: https://doi.org/10.1124/dmd.112.045500
Prior, Wei Wei
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
R
Radominska-Pandya, Anna
- You have accessRole of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10Barbara Fedejko-Kap, Stacie M. Bratton, Moshe Finel, Anna Radominska-Pandya and Zofia MazerskaDrug Metabolism and Disposition September 2012, 40 (9) 1736-1743; DOI: https://doi.org/10.1124/dmd.112.045401
Reynolds, Christine
- You have accessMetabolism and Pharmacokinetics of Indacaterol in HumansMark Kagan, Jeremy Dain, Lana Peng and Christine ReynoldsDrug Metabolism and Disposition September 2012, 40 (9) 1712-1722; DOI: https://doi.org/10.1124/dmd.112.046151
Rodrigues, A. David
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Rodriguez, Alice L.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Rush, Roger
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
S
Säll, Carolina
- You have accessProgress Curve Mechanistic Modeling Approach for Assessing Time-Dependent Inhibition of CYP3A4Howard J. Burt, Henry Pertinez, Carolina Säll, Claire Collins, Ruth Hyland, J. Brian Houston and Aleksandra GaletinDrug Metabolism and Disposition September 2012, 40 (9) 1658-1667; DOI: https://doi.org/10.1124/dmd.112.046078
Salphati, Laurent
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Sampath, Deepak
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Sanchez-Ponce, Raymundo
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Santomango, Tammy S.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Scheffer, George L.
- You have accessAltered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver DiseaseMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Michael J. Kopplin, George L. Scheffer, Walter T. Klimecki, A. Jay Gandolfi and Nathan J. CherringtonDrug Metabolism and Disposition September 2012, 40 (9) 1817-1824; DOI: https://doi.org/10.1124/dmd.112.046177
Scicinski, Jan
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
Scott, Emily E.
- You have accessEvaluation of Inhibition Selectivity for Human Cytochrome P450 2A EnzymesEva S. Stephens, Agnes A. Walsh and Emily E. ScottDrug Metabolism and Disposition September 2012, 40 (9) 1797-1802; DOI: https://doi.org/10.1124/dmd.112.045161
Shen, Guoxiang
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Shu, Yue-Zhong
- You have accessA Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde OxidaseVinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong ShuDrug Metabolism and Disposition September 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545
Song, Xinyi
- You have accessDiscovery of a Highly Selective CYP3A4 Inhibitor Suitable for Reaction Phenotyping Studies and Differentiation of CYP3A4 and CYP3A5Xiaohai Li, Xinyi Song, Theodore M. Kamenecka and Michael D. CameronDrug Metabolism and Disposition September 2012, 40 (9) 1803-1809; DOI: https://doi.org/10.1124/dmd.112.046144
Stec, Donald
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Stephens, Eva S.
- You have accessEvaluation of Inhibition Selectivity for Human Cytochrome P450 2A EnzymesEva S. Stephens, Agnes A. Walsh and Emily E. ScottDrug Metabolism and Disposition September 2012, 40 (9) 1797-1802; DOI: https://doi.org/10.1124/dmd.112.045161
T
Tan, Beijing
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
Taylor, Michael
- You have accessPreclinical Evaluation of the Metabolism and Disposition of RRx-001, a Novel Investigative Anticancer AgentJan Scicinski, Bryan Oronsky, Michael Taylor, Gang Luo, Timothy Musick, Joseph Marini, Christopher M. Adams and William L. FitchDrug Metabolism and Disposition September 2012, 40 (9) 1810-1816; DOI: https://doi.org/10.1124/dmd.112.046755
Teramura, Toshio
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Terashita, Shigeyuki
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Tetsuka, Kazuhiro
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Thorndike, Denise
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Trapa, Patrick
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
Tremaine, Larry M.
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
V
Venable, Daryl F.
- You have accessThe Role of Aldehyde Oxidase and Xanthine Oxidase in the Biotransformation of a Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5Ryan D. Morrison, Anna L. Blobaum, Frank W. Byers, Tammy S. Santomango, Thomas M. Bridges, Donald Stec, Katrina A. Brewer, Raymundo Sanchez-Ponce, Melany M. Corlew, Roger Rush, Andrew S. Felts, Jason Manka, Brittney S. Bates, Daryl F. Venable, Alice L. Rodriguez, Carrie K. Jones, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte and J. Scott DanielsDrug Metabolism and Disposition September 2012, 40 (9) 1834-1845; DOI: https://doi.org/10.1124/dmd.112.046136
Vuppugalla, Ragini
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
W
Wagner, Andrew
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Walker, Gregory S.
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Walsh, Agnes A.
- You have accessEvaluation of Inhibition Selectivity for Human Cytochrome P450 2A EnzymesEva S. Stephens, Agnes A. Walsh and Emily E. ScottDrug Metabolism and Disposition September 2012, 40 (9) 1797-1802; DOI: https://doi.org/10.1124/dmd.112.045161
Walsky, Robert L.
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Wan, Yakun
- You have accessEvaluation of P450 Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human HepatocytesJie Xing, Brian J. Kirby, Dale Whittington, Yakun Wan and David R. GoodlettDrug Metabolism and Disposition September 2012, 40 (9) 1757-1764; DOI: https://doi.org/10.1124/dmd.112.045765
Wang, Haiqing
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Wang, Lifei
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Wangsa, Julie
- You have accessExcretion and Metabolism of Milnacipran in Humans after Oral Administration of Milnacipran HydrochlorideFanying Li, Christina Chin, Julie Wangsa and John HoDrug Metabolism and Disposition September 2012, 40 (9) 1723-1735; DOI: https://doi.org/10.1124/dmd.112.045120
West, Michael
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Whittington, Dale
- You have accessEvaluation of P450 Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human HepatocytesJie Xing, Brian J. Kirby, Dale Whittington, Yakun Wan and David R. GoodlettDrug Metabolism and Disposition September 2012, 40 (9) 1757-1764; DOI: https://doi.org/10.1124/dmd.112.045765
Wolford, Angela C.
- You have accessA Novel Relay Method for Determining Low-Clearance ValuesLi Di, Patrick Trapa, R. Scott Obach, Karen Atkinson, Yi-An Bi, Angela C. Wolford, Beijing Tan, Thomas S. McDonald, Yurong Lai and Larry M. TremaineDrug Metabolism and Disposition September 2012, 40 (9) 1860-1865; DOI: https://doi.org/10.1124/dmd.112.046425
Wong, Susan
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
X
Xing, Jie
- You have accessEvaluation of P450 Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human HepatocytesJie Xing, Brian J. Kirby, Dale Whittington, Yakun Wan and David R. GoodlettDrug Metabolism and Disposition September 2012, 40 (9) 1757-1764; DOI: https://doi.org/10.1124/dmd.112.045765
Y
Yamano, Katsuhiro
- You have accessQuantitative Prediction of Human Intestinal Glucuronidation Effects on Intestinal Availability of UDP-Glucuronosyltransferase Substrates Using In Vitro DataFumihiro Nakamori, Yoichi Naritomi, Ken-ichi Hosoya, Hiroyuki Moriguchi, Kazuhiro Tetsuka, Takako Furukawa, Keitaro Kadono, Katsuhiro Yamano, Shigeyuki Terashita and Toshio TeramuraDrug Metabolism and Disposition September 2012, 40 (9) 1771-1777; DOI: https://doi.org/10.1124/dmd.112.045476
Yang, Zheng
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
Z
Zamek-Gliszczynski, Maciej J.
- You have accessCharacterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein PharmacokineticsMaciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William HigginsDrug Metabolism and Disposition September 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508
Zhang, Donglu
- You have accessDevelopment of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated BiologicHaiqing Wang, Lifei Wang, Kai Cao, Stuart L. Emanuel, Paul Morin, Zheng Lin, Guoxiang Shen, Jennifer Hosbach, Donglu Zhang, Samuel Bonacorsi, A. David Rodrigues and Zheng YangDrug Metabolism and Disposition September 2012, 40 (9) 1677-1685; DOI: https://doi.org/10.1124/dmd.112.044792
Zhang, Haoming
- You have accessMechanism-Based Inactivation of Cytochrome P450 2B6 by Methadone through Destruction of Prosthetic HemeHemali T. Amunugama, Haoming Zhang and Paul F. HollenbergDrug Metabolism and Disposition September 2012, 40 (9) 1765-1770; DOI: https://doi.org/10.1124/dmd.112.045971
Zhang, Xiaolin
- You have accessPreclinical Assessment of the Absorption and Disposition of the Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor GDC-0980 and Prediction of Its Pharmacokinetics and Efficacy in HumanLaurent Salphati, Jodie Pang, Emile G. Plise, Leslie B. Lee, Alan G. Olivero, Wei Wei Prior, Deepak Sampath, Susan Wong and Xiaolin ZhangDrug Metabolism and Disposition September 2012, 40 (9) 1785-1796; DOI: https://doi.org/10.1124/dmd.112.046052
Zhou, Sue
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Zientek, Michael A.
- You have accessSelective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of DrugsRobert L. Walsky, R. Scott Obach, Ruth Hyland, Ping Kang, Sue Zhou, Michael West, Kieran F. Geoghegan, Christopher J. Helal, Gregory S. Walker, Theunis C. Goosen and Michael A. ZientekDrug Metabolism and Disposition September 2012, 40 (9) 1686-1697; DOI: https://doi.org/10.1124/dmd.112.045302
Zvyaga, Tatyana
- You have accessEvaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda and A. David RodriguesDrug Metabolism and Disposition September 2012, 40 (9) 1698-1711; DOI: https://doi.org/10.1124/dmd.112.045575
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