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Research ArticleArticle

A Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde Oxidase

Vinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong Shu
Drug Metabolism and Disposition September 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545

Article Information

vol. 40 no. 9 1668-1676
DOI 
https://doi.org/10.1124/dmd.112.044545
PubMed 
22621803
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 8, 2012
  • Accepted May 23, 2012
  • Published online August 17, 2012.

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Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Vinod K. Arora,
  2. Thomas Philip,
  3. Stella Huang and
  4. Yue-Zhong Shu
  1. Departments of Biotransformation (V.K.A., T.P., Y.-Z.S.) and Discovery Analytical Sciences (S.H.), Bristol-Myers Squibb Research and Development, Wallingford, Connecticut
  1. Address correspondence to:
    Vinod K. Arora, Department of Biotransformation, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492. E-mail: vinod.arora{at}bms.com
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Research ArticleArticle

ALDEHYDE OXIDASE-MEDIATED RING OXIDATION OF 2H-OXAZOLE

Vinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong Shu
Drug Metabolism and Disposition September 1, 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545
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