A Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde Oxidase

Vinod K. Arora; Thomas Philip; Stella Huang; Yue-Zhong Shu

doi:10.1124/dmd.112.044545

Research ArticleArticle

A Novel Ring Oxidation of 4- or 5-Substituted 2H-Oxazole to Corresponding 2-Oxazolone Catalyzed by Cytosolic Aldehyde Oxidase

Vinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong Shu

Drug Metabolism and Disposition September 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545

Vinod K. Arora

Departments of Biotransformation (V.K.A., T.P., Y.-Z.S.) and Discovery Analytical Sciences (S.H.), Bristol-Myers Squibb Research and Development, Wallingford, Connecticut

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Thomas Philip

Departments of Biotransformation (V.K.A., T.P., Y.-Z.S.) and Discovery Analytical Sciences (S.H.), Bristol-Myers Squibb Research and Development, Wallingford, Connecticut

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Stella Huang

Departments of Biotransformation (V.K.A., T.P., Y.-Z.S.) and Discovery Analytical Sciences (S.H.), Bristol-Myers Squibb Research and Development, Wallingford, Connecticut

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Yue-Zhong Shu

Departments of Biotransformation (V.K.A., T.P., Y.-Z.S.) and Discovery Analytical Sciences (S.H.), Bristol-Myers Squibb Research and Development, Wallingford, Connecticut

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Drug Metabolism and Disposition

Vol. 40, Issue 9

1 Sep 2012

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Research ArticleArticle

ALDEHYDE OXIDASE-MEDIATED RING OXIDATION OF 2H-OXAZOLE

Vinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong Shu

Drug Metabolism and Disposition September 1, 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545

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Research ArticleArticle

ALDEHYDE OXIDASE-MEDIATED RING OXIDATION OF 2H-OXAZOLE

Vinod K. Arora, Thomas Philip, Stella Huang and Yue-Zhong Shu

Drug Metabolism and Disposition September 1, 2012, 40 (9) 1668-1676; DOI: https://doi.org/10.1124/dmd.112.044545

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