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Research ArticleArticle

Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein Pharmacokinetics

Maciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William Higgins
Drug Metabolism and Disposition September 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508

Article Information

vol. 40 no. 9 1825-1833
DOI 
https://doi.org/10.1124/dmd.112.046508
PubMed 
22711747
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 27, 2012
  • Accepted June 18, 2012
  • Published online August 17, 2012.

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Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Maciej J. Zamek-Gliszczynski,
  2. David W. Bedwell,
  3. Jing Q. Bao and
  4. J. William Higgins
  1. Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana
  1. Address correspondence to:
    Dr. Maciej J. Zamek-Gliszczynski, Lilly Corporate Center, Indianapolis, IN 46285. E-mail: m_zamek-gliszczynski{at}lilly.com
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Research ArticleArticle

PK CHARACTERIZATION OF P-gp, Bcrp, AND Mrp2 KNOCKOUT RATS

Maciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William Higgins
Drug Metabolism and Disposition September 1, 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508
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