Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein Pharmacokinetics

Maciej J. Zamek-Gliszczynski; David W. Bedwell; Jing Q. Bao; J. William Higgins

doi:10.1124/dmd.112.046508

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Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 Knockout Rats Using Loperamide, Paclitaxel, Sulfasalazine, and Carboxydichlorofluorescein Pharmacokinetics

Maciej J. Zamek-Gliszczynski, David W. Bedwell, Jing Q. Bao and J. William Higgins

Drug Metabolism and Disposition September 2012, 40 (9) 1825-1833; DOI: https://doi.org/10.1124/dmd.112.046508

Maciej J. Zamek-Gliszczynski

Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana

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David W. Bedwell

Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana

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Jing Q. Bao

Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana

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J. William Higgins

Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana

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Drug Metabolism and Disposition

Vol. 40, Issue 9

1 Sep 2012

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