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Index by author

January 01, 2013; Volume 41,Issue 1

A

  1. Aasa, Jenny

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  2. Abad-Santos, Francisco

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

  3. Agarwal, Sagar

    1. Function of the Blood-Brain Barrier and Restriction of Drug Delivery to Invasive Glioma Cells: Findings in an Orthotopic Rat Xenograft Model of Glioma
      Sagar Agarwal, Pooja Manchanda, Michael A. Vogelbaum, John R. Ohlfest and William F. Elmquist
      Drug Metabolism and Disposition January 2013, 41 (1) 33-39; DOI: https://doi.org/10.1124/dmd.112.048322

  4. Akamine, Yumiko

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  5. Alhonen, Leena

    1. Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N1-Acetyltransferase and Thialysine Acetyltransferase
      Mervi T. Hyvönen, Janne Weisell, Alex R. Khomutov, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition January 2013, 41 (1) 30-32; DOI: https://doi.org/10.1124/dmd.112.047274

  6. Alsina, Melissa

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  7. Anderson, Erica R.

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

B

  1. Backman, Janne T.

    1. Autoinhibition of CYP3A4 Leads to Important Role of CYP2C8 in Imatinib Metabolism: Variability in CYP2C8 Activity May Alter Plasma Concentrations and Response
      Anne M. Filppula, Mikko Neuvonen, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition January 2013, 41 (1) 50-59; DOI: https://doi.org/10.1124/dmd.112.048017

  2. Badros, Ashraf

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  3. Bal, Jo

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  4. Baranczewski, Pawel

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  5. Barr, John T.

    1. Evidence for Substrate-Dependent Inhibition Profiles for Human Liver Aldehyde Oxidase
      John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition January 2013, 41 (1) 24-29; DOI: https://doi.org/10.1124/dmd.112.048546

  6. Beaumont, Claire

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  7. Bell, Guinevere H.

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

  8. Bernstein, Hilary

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

  9. Berry, Loren M.

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  10. Bjelland, Thor Wilhelm

    1. Effects of Hypothermia on the Disposition of Morphine, Midazolam, Fentanyl, and Propofol in Intensive Care Unit Patients
      Thor Wilhelm Bjelland, Pål Klepstad, Bjørn Olav Haugen, Turid Nilsen and Ola Dale
      Drug Metabolism and Disposition January 2013, 41 (1) 214-223; DOI: https://doi.org/10.1124/dmd.112.045567

  11. Bomba, Darrin

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  12. Bottlaender, Michel

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  13. Brake, Rachael L.

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  14. Brouwer, Kim L. R.

    1. Combination Lopinavir and Ritonavir Alter Exogenous and Endogenous Bile Acid Disposition in Sandwich-Cultured Rat Hepatocytes
      LaToya M. Griffin, Paul B. Watkins, Cassandra H. Perry, Robert L. St. Claire and Kim L. R. Brouwer
      Drug Metabolism and Disposition January 2013, 41 (1) 188-196; DOI: https://doi.org/10.1124/dmd.112.047225

  15. Bueters, Tjerk

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  16. Bushey, Ryan T.

    1. Importance of UDP-Glucuronosyltransferases 2A2 and 2A3 in Tobacco Carcinogen Metabolism
      Ryan T. Bushey, Douglas F. Dluzen and Philip Lazarus
      Drug Metabolism and Disposition January 2013, 41 (1) 170-179; DOI: https://doi.org/10.1124/dmd.112.049171

C

  1. Cabaleiro, Teresa

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

  2. Chen, Chi

    1. Characterization of Differential Cocaine Metabolism in Mouse and Rat through Metabolomics-Guided Metabolite Profiling
      Dan Yao, Xiaolei Shi, Lei Wang, Blake A. Gosnell and Chi Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 79-88; DOI: https://doi.org/10.1124/dmd.112.048678

  3. Chen, Li

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  4. Chiang, John Y. L.

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

D

  1. Dale, Ola

    1. Effects of Hypothermia on the Disposition of Morphine, Midazolam, Fentanyl, and Propofol in Intensive Care Unit Patients
      Thor Wilhelm Bjelland, Pål Klepstad, Bjørn Olav Haugen, Turid Nilsen and Ola Dale
      Drug Metabolism and Disposition January 2013, 41 (1) 214-223; DOI: https://doi.org/10.1124/dmd.112.045567

  2. Dalton, James T.

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  3. Damont, Annelaure

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  4. Ding, Xinxin

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991
    2. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  5. Distrutti, Eleonora

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  6. Dluzen, Douglas F.

    1. Importance of UDP-Glucuronosyltransferases 2A2 and 2A3 in Tobacco Carcinogen Metabolism
      Ryan T. Bushey, Douglas F. Dluzen and Philip Lazarus
      Drug Metabolism and Disposition January 2013, 41 (1) 170-179; DOI: https://doi.org/10.1124/dmd.112.049171

  7. Dollé, Frédéric

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  8. Dunbar, Anwar

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

E

  1. Ebner, Thomas

    1. Evaluation and Prediction of Potential Drug-Drug Interactions of Linagliptin Using In Vitro Cell Culture Methods
      Naoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, Thomas Ebner and Olaf Schaefer
      Drug Metabolism and Disposition January 2013, 41 (1) 149-158; DOI: https://doi.org/10.1124/dmd.112.048470

  2. Eklund, Göran

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  3. Elmquist, William F.

    1. Function of the Blood-Brain Barrier and Restriction of Drug Delivery to Invasive Glioma Cells: Findings in an Orthotopic Rat Xenograft Model of Glioma
      Sagar Agarwal, Pooja Manchanda, Michael A. Vogelbaum, John R. Ohlfest and William F. Elmquist
      Drug Metabolism and Disposition January 2013, 41 (1) 33-39; DOI: https://doi.org/10.1124/dmd.112.048322

  4. Emmons, Amanda J.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

F

  1. Fang, Ying

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  2. Fei, Jian

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  3. Felgate, Clive C.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  4. Filppula, Anne M.

    1. Autoinhibition of CYP3A4 Leads to Important Role of CYP2C8 in Imatinib Metabolism: Variability in CYP2C8 Activity May Alter Plasma Concentrations and Response
      Anne M. Filppula, Mikko Neuvonen, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition January 2013, 41 (1) 50-59; DOI: https://doi.org/10.1124/dmd.112.048017

  5. Finn, Robert D.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  6. Fiorucci, Stefano

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  7. Flück, Christa E.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  8. Fukizawa, Shinya

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

G

  1. Gosnell, Blake A.

    1. Characterization of Differential Cocaine Metabolism in Mouse and Rat through Metabolomics-Guided Metabolite Profiling
      Dan Yao, Xiaolei Shi, Lei Wang, Blake A. Gosnell and Chi Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 79-88; DOI: https://doi.org/10.1124/dmd.112.048678

  2. Goutal, Sébastien

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  3. Griffin, LaToya M.

    1. Combination Lopinavir and Ritonavir Alter Exogenous and Endogenous Bile Acid Disposition in Sandwich-Cultured Rat Hepatocytes
      LaToya M. Griffin, Paul B. Watkins, Cassandra H. Perry, Robert L. St. Claire and Kim L. R. Brouwer
      Drug Metabolism and Disposition January 2013, 41 (1) 188-196; DOI: https://doi.org/10.1124/dmd.112.047225

  4. Grillo, Mark P.

    1. Interaction of γ-Glutamyltranspeptidase with Ibuprofen-S-Acyl-Glutathione In Vitro and In Vivo in Human
      Mark P. Grillo, Michelle Tadano Lohr and Smriti Khera
      Drug Metabolism and Disposition January 2013, 41 (1) 111-121; DOI: https://doi.org/10.1124/dmd.112.048645

  5. Gu, Jun

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  6. Guo, Grace L.

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

H

  1. Harrell, Andrew W.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  2. Haugen, Bjørn Olav

    1. Effects of Hypothermia on the Disposition of Morphine, Midazolam, Fentanyl, and Propofol in Intensive Care Unit Patients
      Thor Wilhelm Bjelland, Pål Klepstad, Bjørn Olav Haugen, Turid Nilsen and Ola Dale
      Drug Metabolism and Disposition January 2013, 41 (1) 214-223; DOI: https://doi.org/10.1124/dmd.112.045567

  3. Henderson, Colin J.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  4. Hollenberg, Paul F.

    1. Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism
      Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2013, 41 (1) 101-110; DOI: https://doi.org/10.1124/dmd.112.046094

  5. Hu, Yin

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  6. Hyvönen, Mervi T.

    1. Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N1-Acetyltransferase and Thialysine Acetyltransferase
      Mervi T. Hyvönen, Janne Weisell, Alex R. Khomutov, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition January 2013, 41 (1) 30-32; DOI: https://doi.org/10.1124/dmd.112.047274

I

  1. Ikejiri, Kazuaki

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  2. Imai, Satoki

    1. DNA Methylation and Histone Modification Profiles of Mouse Organic Anion Transporting Polypeptides
      Satoki Imai, Ryota Kikuchi, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 72-78; DOI: https://doi.org/10.1124/dmd.112.047969

  3. Imai, Teruko

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

  4. Infante, Jeffrey R.

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  5. Ishiguro, Naoki

    1. Evaluation and Prediction of Potential Drug-Drug Interactions of Linagliptin Using In Vitro Cell Culture Methods
      Naoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, Thomas Ebner and Olaf Schaefer
      Drug Metabolism and Disposition January 2013, 41 (1) 149-158; DOI: https://doi.org/10.1124/dmd.112.048470

  6. Izumi, Takashi

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

J

  1. Jones, Jeffrey P.

    1. Evidence for Substrate-Dependent Inhibition Profiles for Human Liver Aldehyde Oxidase
      John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition January 2013, 41 (1) 24-29; DOI: https://doi.org/10.1124/dmd.112.048546

  2. Jones, Ryan D.

    1. Carboxylesterases Are Uniquely Expressed among Tissues and Regulated by Nuclear Hormone Receptors in the Mouse
      Ryan D. Jones, Anna M. Taylor, Ernest Y. Tong and Joyce J. Repa
      Drug Metabolism and Disposition January 2013, 41 (1) 40-49; DOI: https://doi.org/10.1124/dmd.112.048397

K

  1. Kagan, Leonid

    1. Mechanisms of Subcutaneous Absorption of Rituximab in Rats
      Leonid Kagan and Donald E. Mager
      Drug Metabolism and Disposition January 2013, 41 (1) 248-255; DOI: https://doi.org/10.1124/dmd.112.048496

  2. Kanamitsu, Kayoko

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  3. Kassiou, Michael

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  4. Keinänen, Tuomo A.

    1. Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N1-Acetyltransferase and Thialysine Acetyltransferase
      Mervi T. Hyvönen, Janne Weisell, Alex R. Khomutov, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition January 2013, 41 (1) 30-32; DOI: https://doi.org/10.1124/dmd.112.047274

  5. Kempsford, Rodger D.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  6. Kenaan, Cesar

    1. Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism
      Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2013, 41 (1) 101-110; DOI: https://doi.org/10.1124/dmd.112.046094

  7. Khera, Smriti

    1. Interaction of γ-Glutamyltranspeptidase with Ibuprofen-S-Acyl-Glutathione In Vitro and In Vivo in Human
      Mark P. Grillo, Michelle Tadano Lohr and Smriti Khera
      Drug Metabolism and Disposition January 2013, 41 (1) 111-121; DOI: https://doi.org/10.1124/dmd.112.048645

  8. Khomutov, Alex R.

    1. Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N1-Acetyltransferase and Thialysine Acetyltransferase
      Mervi T. Hyvönen, Janne Weisell, Alex R. Khomutov, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition January 2013, 41 (1) 30-32; DOI: https://doi.org/10.1124/dmd.112.047274

  9. Kikuchi, Ryota

    1. DNA Methylation and Histone Modification Profiles of Mouse Organic Anion Transporting Polypeptides
      Satoki Imai, Ryota Kikuchi, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 72-78; DOI: https://doi.org/10.1124/dmd.112.047969

  10. Kirk, Christopher

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  11. Kishimoto, Wataru

    1. Evaluation and Prediction of Potential Drug-Drug Interactions of Linagliptin Using In Vitro Cell Culture Methods
      Naoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, Thomas Ebner and Olaf Schaefer
      Drug Metabolism and Disposition January 2013, 41 (1) 149-158; DOI: https://doi.org/10.1124/dmd.112.048470

  12. Klepstad, Pål

    1. Effects of Hypothermia on the Disposition of Morphine, Midazolam, Fentanyl, and Propofol in Intensive Care Unit Patients
      Thor Wilhelm Bjelland, Pål Klepstad, Bjørn Olav Haugen, Turid Nilsen and Ola Dale
      Drug Metabolism and Disposition January 2013, 41 (1) 214-223; DOI: https://doi.org/10.1124/dmd.112.045567

  13. Kluetzman, Kerri

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  14. Kobayashi, Nobuhiro

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

  15. Kong, Bo

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  16. Koyama, Kumiko

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

  17. Kusuhara, Hiroyuki

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330
    2. DNA Methylation and Histone Modification Profiles of Mouse Organic Anion Transporting Polypeptides
      Satoki Imai, Ryota Kikuchi, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 72-78; DOI: https://doi.org/10.1124/dmd.112.047969

L

  1. Laitila, Jouko

    1. Autoinhibition of CYP3A4 Leads to Important Role of CYP2C8 in Imatinib Metabolism: Variability in CYP2C8 Activity May Alter Plasma Concentrations and Response
      Anne M. Filppula, Mikko Neuvonen, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition January 2013, 41 (1) 50-59; DOI: https://doi.org/10.1124/dmd.112.048017

  2. Lazarus, Philip

    1. Importance of UDP-Glucuronosyltransferases 2A2 and 2A3 in Tobacco Carcinogen Metabolism
      Ryan T. Bushey, Douglas F. Dluzen and Philip Lazarus
      Drug Metabolism and Disposition January 2013, 41 (1) 170-179; DOI: https://doi.org/10.1124/dmd.112.049171

  3. Lewis, Richard T.

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  4. Li, Jin

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  5. Li, Lei

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  6. Lin, Hsia-lien

    1. Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism
      Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2013, 41 (1) 101-110; DOI: https://doi.org/10.1124/dmd.112.046094

  7. Lindgren, Anders

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  8. Liu, Fang

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  9. Liu, Jingzhou

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  10. Lohr, Michelle Tadano

    1. Interaction of γ-Glutamyltranspeptidase with Ibuprofen-S-Acyl-Glutathione In Vitro and In Vivo in Human
      Mark P. Grillo, Michelle Tadano Lohr and Smriti Khera
      Drug Metabolism and Disposition January 2013, 41 (1) 111-121; DOI: https://doi.org/10.1124/dmd.112.048645

  11. López-Rodríguez, Rosario

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

M

  1. Mager, Donald E.

    1. Mechanisms of Subcutaneous Absorption of Rituximab in Rats
      Leonid Kagan and Donald E. Mager
      Drug Metabolism and Disposition January 2013, 41 (1) 248-255; DOI: https://doi.org/10.1124/dmd.112.048496

  2. Malcolm, Robert J.

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

  3. Malmquist, Jonas

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

  4. Manchanda, Pooja

    1. Function of the Blood-Brain Barrier and Restriction of Drug Delivery to Invasive Glioma Cells: Findings in an Orthotopic Rat Xenograft Model of Glioma
      Sagar Agarwal, Pooja Manchanda, Michael A. Vogelbaum, John R. Ohlfest and William F. Elmquist
      Drug Metabolism and Disposition January 2013, 41 (1) 33-39; DOI: https://doi.org/10.1124/dmd.112.048322

  5. Maruyama, Toru

    1. Carbon Monoxide–Bound Red Blood Cells Protect Red Blood Cell Transfusion-Induced Hepatic Cytochrome P450 Impairment in Hemorrhagic-Shock Rats
      Shigeru Ogaki, Kazuaki Taguchi, Hiroshi Watanabe, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition January 2013, 41 (1) 141-148; DOI: https://doi.org/10.1124/dmd.112.048744

  6. McLaughlin, Lesley A.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  7. Mei, Ye

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  8. Miura, Masatomo

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  9. Moore, Earl

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

N

  1. Nakai, Daisuke

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

  2. Nakai, Naoko

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

  3. Narayanan, Ramesh

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  4. Neuvonen, Mikko

    1. Autoinhibition of CYP3A4 Leads to Important Role of CYP2C8 in Imatinib Metabolism: Variability in CYP2C8 Activity May Alter Plasma Concentrations and Response
      Anne M. Filppula, Mikko Neuvonen, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition January 2013, 41 (1) 50-59; DOI: https://doi.org/10.1124/dmd.112.048017

  5. Neuvonen, Pertti J.

    1. Autoinhibition of CYP3A4 Leads to Important Role of CYP2C8 in Imatinib Metabolism: Variability in CYP2C8 Activity May Alter Plasma Concentrations and Response
      Anne M. Filppula, Mikko Neuvonen, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition January 2013, 41 (1) 50-59; DOI: https://doi.org/10.1124/dmd.112.048017

  6. Nilsen, Turid

    1. Effects of Hypothermia on the Disposition of Morphine, Midazolam, Fentanyl, and Propofol in Intensive Care Unit Patients
      Thor Wilhelm Bjelland, Pål Klepstad, Bjørn Olav Haugen, Turid Nilsen and Ola Dale
      Drug Metabolism and Disposition January 2013, 41 (1) 214-223; DOI: https://doi.org/10.1124/dmd.112.045567

  7. Novalbos, Jesús

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

O

  1. Ochoa, Dolores

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

  2. Ogaki, Shigeru

    1. Carbon Monoxide–Bound Red Blood Cells Protect Red Blood Cell Transfusion-Induced Hepatic Cytochrome P450 Impairment in Hemorrhagic-Shock Rats
      Shigeru Ogaki, Kazuaki Taguchi, Hiroshi Watanabe, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition January 2013, 41 (1) 141-148; DOI: https://doi.org/10.1124/dmd.112.048744

  3. Ohlfest, John R.

    1. Function of the Blood-Brain Barrier and Restriction of Drug Delivery to Invasive Glioma Cells: Findings in an Orthotopic Rat Xenograft Model of Glioma
      Sagar Agarwal, Pooja Manchanda, Michael A. Vogelbaum, John R. Ohlfest and William F. Elmquist
      Drug Metabolism and Disposition January 2013, 41 (1) 33-39; DOI: https://doi.org/10.1124/dmd.112.048322

  4. Otagiri, Masaki

    1. Carbon Monoxide–Bound Red Blood Cells Protect Red Blood Cell Transfusion-Induced Hepatic Cytochrome P450 Impairment in Hemorrhagic-Shock Rats
      Shigeru Ogaki, Kazuaki Taguchi, Hiroshi Watanabe, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition January 2013, 41 (1) 141-148; DOI: https://doi.org/10.1124/dmd.112.048744

P

  1. Pandey, Amit V.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  2. Papadopoulos, Kyriakos

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  3. Patel, Nainesh H.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  4. Patrick, Kennerly S.

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

  5. Pearce, Sebastian J.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  6. Pereira, Adrian I.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  7. Perry, Cassandra H.

    1. Combination Lopinavir and Ritonavir Alter Exogenous and Endogenous Bile Acid Disposition in Sandwich-Cultured Rat Hepatocytes
      LaToya M. Griffin, Paul B. Watkins, Cassandra H. Perry, Robert L. St. Claire and Kim L. R. Brouwer
      Drug Metabolism and Disposition January 2013, 41 (1) 188-196; DOI: https://doi.org/10.1124/dmd.112.047225

  8. Peyronneau, Marie-Anne

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  9. Porter, Todd D.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  10. Pratt-Hyatt, Matthew J.

    1. Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism
      Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2013, 41 (1) 101-110; DOI: https://doi.org/10.1124/dmd.112.046094

  11. Prieto-Pérez, Rocío

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

R

  1. Reeves, Owen T.

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

  2. Ren, Shuang

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  3. Renga, Barbara

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  4. Repa, Joyce J.

    1. Carboxylesterases Are Uniquely Expressed among Tissues and Regulated by Nuclear Hormone Receptors in the Mouse
      Ryan D. Jones, Anna M. Taylor, Ernest Y. Tong and Joyce J. Repa
      Drug Metabolism and Disposition January 2013, 41 (1) 40-49; DOI: https://doi.org/10.1124/dmd.112.048397

  5. Riddick, David S.

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  6. Roberts, Andy D.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  7. Román, Manuel

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

  8. Ronseaux, Sebastien

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

S

  1. Saba, Wadad

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  2. Saffran, Douglas C.

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  3. Schaefer, Olaf

    1. Evaluation and Prediction of Potential Drug-Drug Interactions of Linagliptin Using In Vitro Cell Culture Methods
      Naoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, Thomas Ebner and Olaf Schaefer
      Drug Metabolism and Disposition January 2013, 41 (1) 149-158; DOI: https://doi.org/10.1124/dmd.112.048470

  4. Shea, Erin V.

    1. Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism
      Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2013, 41 (1) 101-110; DOI: https://doi.org/10.1124/dmd.112.046094

  5. Shi, Xiaolei

    1. Characterization of Differential Cocaine Metabolism in Mouse and Rat through Metabolomics-Guided Metabolite Profiling
      Dan Yao, Xiaolei Shi, Lei Wang, Blake A. Gosnell and Chi Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 79-88; DOI: https://doi.org/10.1124/dmd.112.048678

  6. Shimizu, Hidetada

    1. Evaluation and Prediction of Potential Drug-Drug Interactions of Linagliptin Using In Vitro Cell Culture Methods
      Naoki Ishiguro, Hidetada Shimizu, Wataru Kishimoto, Thomas Ebner and Olaf Schaefer
      Drug Metabolism and Disposition January 2013, 41 (1) 149-158; DOI: https://doi.org/10.1124/dmd.112.048470

  7. Siederer, Sarah K.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

  8. St. Claire, Robert L.

    1. Combination Lopinavir and Ritonavir Alter Exogenous and Endogenous Bile Acid Disposition in Sandwich-Cultured Rat Hepatocytes
      LaToya M. Griffin, Paul B. Watkins, Cassandra H. Perry, Robert L. St. Claire and Kim L. R. Brouwer
      Drug Metabolism and Disposition January 2013, 41 (1) 188-196; DOI: https://doi.org/10.1124/dmd.112.047225

  9. Straughn, Arthur B.

    1. Differential Influences of Ethanol on Early Exposure to Racemic Methylphenidate Compared with Dexmethylphenidate in Humans
      Kennerly S. Patrick, Arthur B. Straughn, Owen T. Reeves, Hilary Bernstein, Guinevere H. Bell, Erica R. Anderson and Robert J. Malcolm
      Drug Metabolism and Disposition January 2013, 41 (1) 197-205; DOI: https://doi.org/10.1124/dmd.112.048595

  10. Sugiyama, Yuichi

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330
    2. DNA Methylation and Histone Modification Profiles of Mouse Organic Anion Transporting Polypeptides
      Satoki Imai, Ryota Kikuchi, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 72-78; DOI: https://doi.org/10.1124/dmd.112.047969

  11. Swanson, Hollie I.

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

T

  1. Taguchi, Kazuaki

    1. Carbon Monoxide–Bound Red Blood Cells Protect Red Blood Cell Transfusion-Induced Hepatic Cytochrome P450 Impairment in Hemorrhagic-Shock Rats
      Shigeru Ogaki, Kazuaki Taguchi, Hiroshi Watanabe, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition January 2013, 41 (1) 141-148; DOI: https://doi.org/10.1124/dmd.112.048744

  2. Takahashi, Makoto

    1. Pharmacokinetic Mechanism Involved in the Prolonged High Retention of Laninamivir in Mouse Respiratory Tissues after Intranasal Administration of its Prodrug Laninamivir Octanoate
      Kumiko Koyama, Daisuke Nakai, Makoto Takahashi, Naoko Nakai, Nobuhiro Kobayashi, Teruko Imai and Takashi Izumi
      Drug Metabolism and Disposition January 2013, 41 (1) 180-187; DOI: https://doi.org/10.1124/dmd.112.048280

  3. Talegón, María

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

  4. Taylor, Anna M.

    1. Carboxylesterases Are Uniquely Expressed among Tissues and Regulated by Nuclear Hormone Receptors in the Mouse
      Ryan D. Jones, Anna M. Taylor, Ernest Y. Tong and Joyce J. Repa
      Drug Metabolism and Disposition January 2013, 41 (1) 40-49; DOI: https://doi.org/10.1124/dmd.112.048397

  5. Teffera, Yohannes

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  6. Thomas, Ann M.

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  7. Tong, Ernest Y.

    1. Carboxylesterases Are Uniquely Expressed among Tissues and Regulated by Nuclear Hormone Receptors in the Mouse
      Ryan D. Jones, Anna M. Taylor, Ernest Y. Tong and Joyce J. Repa
      Drug Metabolism and Disposition January 2013, 41 (1) 40-49; DOI: https://doi.org/10.1124/dmd.112.048397

  8. Turek, Dominika

    1. Effect of Solvents on the Time-Dependent Inhibition of CYP3A4 and the Biotransformation of AZD3839 in Human Liver Microsomes and Hepatocytes
      Jenny Aasa, Yin Hu, Göran Eklund, Anders Lindgren, Pawel Baranczewski, Jonas Malmquist, Dominika Turek and Tjerk Bueters
      Drug Metabolism and Disposition January 2013, 41 (1) 159-169; DOI: https://doi.org/10.1124/dmd.112.047597

U

  1. Uno, Tsukasa

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

V

  1. Valette, Héric

    1. Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand
      Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
      Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

  2. Vepsäläinen, Jouko

    1. Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N1-Acetyltransferase and Thialysine Acetyltransferase
      Mervi T. Hyvönen, Janne Weisell, Alex R. Khomutov, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition January 2013, 41 (1) 30-32; DOI: https://doi.org/10.1124/dmd.112.047274

  3. Vogelbaum, Michael A.

    1. Function of the Blood-Brain Barrier and Restriction of Drug Delivery to Invasive Glioma Cells: Findings in an Orthotopic Rat Xenograft Model of Glioma
      Sagar Agarwal, Pooja Manchanda, Michael A. Vogelbaum, John R. Ohlfest and William F. Elmquist
      Drug Metabolism and Disposition January 2013, 41 (1) 33-39; DOI: https://doi.org/10.1124/dmd.112.048322

W

  1. Wada, Taira

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  2. Wang, Lei

    1. Characterization of Differential Cocaine Metabolism in Mouse and Rat through Metabolomics-Guided Metabolite Profiling
      Dan Yao, Xiaolei Shi, Lei Wang, Blake A. Gosnell and Chi Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 79-88; DOI: https://doi.org/10.1124/dmd.112.048678

  3. Wang, Zhengping

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  4. Watanabe, Hiroshi

    1. Carbon Monoxide–Bound Red Blood Cells Protect Red Blood Cell Transfusion-Induced Hepatic Cytochrome P450 Impairment in Hemorrhagic-Shock Rats
      Shigeru Ogaki, Kazuaki Taguchi, Hiroshi Watanabe, Masaki Otagiri and Toru Maruyama
      Drug Metabolism and Disposition January 2013, 41 (1) 141-148; DOI: https://doi.org/10.1124/dmd.112.048744

  5. Watkins, Paul B.

    1. Combination Lopinavir and Ritonavir Alter Exogenous and Endogenous Bile Acid Disposition in Sandwich-Cultured Rat Hepatocytes
      LaToya M. Griffin, Paul B. Watkins, Cassandra H. Perry, Robert L. St. Claire and Kim L. R. Brouwer
      Drug Metabolism and Disposition January 2013, 41 (1) 188-196; DOI: https://doi.org/10.1124/dmd.112.047225

  6. Wei, Yuan

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  7. Weisell, Janne

    1. Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N1-Acetyltransferase and Thialysine Acetyltransferase
      Mervi T. Hyvönen, Janne Weisell, Alex R. Khomutov, Leena Alhonen, Jouko Vepsäläinen and Tuomo A. Keinänen
      Drug Metabolism and Disposition January 2013, 41 (1) 30-32; DOI: https://doi.org/10.1124/dmd.112.047274

  8. Wojnicz, Aneta

    1. Evaluation of the Relationship between Sex, Polymorphisms in CYP2C8 and CYP2C9, and Pharmacokinetics of Angiotensin Receptor Blockers
      Teresa Cabaleiro, Manuel Román, Dolores Ochoa, María Talegón, Rocío Prieto-Pérez, Aneta Wojnicz, Rosario López-Rodríguez, Jesús Novalbos and Francisco Abad-Santos
      Drug Metabolism and Disposition January 2013, 41 (1) 224-229; DOI: https://doi.org/10.1124/dmd.112.046292

  9. Wolf, C. Roland

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991

  10. Wong, Alvin

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  11. Woo, Tina

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

X

  1. Xie, Wen

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

Y

  1. Yan, S. Frank

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  2. Yang, Jinfu

    1. Clinical Pharmacokinetics, Metabolism, and Drug-Drug Interaction of Carfilzomib
      Zhengping Wang, Jinfu Yang, Christopher Kirk, Ying Fang, Melissa Alsina, Ashraf Badros, Kyriakos Papadopoulos, Alvin Wong, Tina Woo, Darrin Bomba, Jin Li and Jeffrey R. Infante
      Drug Metabolism and Disposition January 2013, 41 (1) 230-237; DOI: https://doi.org/10.1124/dmd.112.047662

  3. Yang, Weizhu

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  4. Yao, Dan

    1. Characterization of Differential Cocaine Metabolism in Mouse and Rat through Metabolomics-Guided Metabolite Profiling
      Dan Yao, Xiaolei Shi, Lei Wang, Blake A. Gosnell and Chi Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 79-88; DOI: https://doi.org/10.1124/dmd.112.048678

  5. Yasui-Furukori, Norio

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  6. Yepuru, Muralimohan

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  7. Yokochi, Miyu

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  8. Yoshida, Kenta

    1. Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects
      Hiroyuki Kusuhara, Masatomo Miura, Norio Yasui-Furukori, Kenta Yoshida, Yumiko Akamine, Miyu Yokochi, Shinya Fukizawa, Kazuaki Ikejiri, Kayoko Kanamitsu, Tsukasa Uno and Yuichi Sugiyama
      Drug Metabolism and Disposition January 2013, 41 (1) 206-213; DOI: https://doi.org/10.1124/dmd.112.048330

  9. Young, Graeme C.

    1. Metabolism and Disposition of Vilanterol, a Long-Acting β2-Adrenoceptor Agonist for Inhalation Use in Humans
      Andrew W. Harrell, Sarah K. Siederer, Jo Bal, Nainesh H. Patel, Graeme C. Young, Clive C. Felgate, Sebastian J. Pearce, Andy D. Roberts, Claire Beaumont, Amanda J. Emmons, Adrian I. Pereira and Rodger D. Kempsford
      Drug Metabolism and Disposition January 2013, 41 (1) 89-100; DOI: https://doi.org/10.1124/dmd.112.048603

Z

  1. Zampella, Angela

    1. Role of Nuclear Receptors in Lipid Dysfunction and Obesity-Related Diseases
      Hollie I. Swanson, Taira Wada, Wen Xie, Barbara Renga, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci, Bo Kong, Ann M. Thomas, Grace L. Guo, Ramesh Narayanan, Muralimohan Yepuru, James T. Dalton and John Y. L. Chiang
      Drug Metabolism and Disposition January 2013, 41 (1) 1-11; DOI: https://doi.org/10.1124/dmd.112.048694

  2. Zeng, Juan

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  3. Zhang, Haoming

    1. Interactions between CYP2E1 and CYP2B4: Effects on Affinity for NADPH-Cytochrome P450 Reductase and Substrate Metabolism
      Cesar Kenaan, Erin V. Shea, Hsia-lien Lin, Haoming Zhang, Matthew J. Pratt-Hyatt and Paul F. Hollenberg
      Drug Metabolism and Disposition January 2013, 41 (1) 101-110; DOI: https://doi.org/10.1124/dmd.112.046094

  4. Zhang, John Z. H.

    1. Discovery and Characterization of Novel, Potent, and Selective Cytochrome P450 2J2 Inhibitors
      Shuang Ren, Juan Zeng, Ye Mei, John Z. H. Zhang, S. Frank Yan, Jian Fei and Li Chen
      Drug Metabolism and Disposition January 2013, 41 (1) 60-71; DOI: https://doi.org/10.1124/dmd.112.048264

  5. Zhang, Qing-Yu

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991
    2. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  6. Zhao, Zhiyang

    1. Impact of Hydrolysis-Mediated Clearance on the Pharmacokinetics of Novel Anaplastic Lymphoma Kinase Inhibitors
      Yohannes Teffera, Loren M. Berry, Rachael L. Brake, Richard T. Lewis, Douglas C. Saffran, Earl Moore, Jingzhou Liu and Zhiyang Zhao
      Drug Metabolism and Disposition January 2013, 41 (1) 238-247; DOI: https://doi.org/10.1124/dmd.112.047993

  7. Zhou, Xin

    1. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model
      Yuan Wei, Lei Li, Xin Zhou, Qing-Yu Zhang, Anwar Dunbar, Fang Liu, Kerri Kluetzman, Weizhu Yang and Xinxin Ding
      Drug Metabolism and Disposition January 2013, 41 (1) 132-140; DOI: https://doi.org/10.1124/dmd.112.048736

  8. Zou, Ling

    1. NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
      David S. Riddick, Xinxin Ding, C. Roland Wolf, Todd D. Porter, Amit V. Pandey, Qing-Yu Zhang, Jun Gu, Robert D. Finn, Sebastien Ronseaux, Lesley A. McLaughlin, Colin J. Henderson, Ling Zou and Christa E. Flück
      Drug Metabolism and Disposition January 2013, 41 (1) 12-23; DOI: https://doi.org/10.1124/dmd.112.048991
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