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Research ArticleArticle

Metabolism and Quantification of [18F]DPA-714, a New TSPO Positron Emission Tomography Radioligand

Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
Drug Metabolism and Disposition January 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342
Marie-Anne Peyronneau
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Wadad Saba
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Sébastien Goutal
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Annelaure Damont
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Frédéric Dollé
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Michael Kassiou
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Michel Bottlaender
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Héric Valette
Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
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Article Information

vol. 41 no. 1 122-131
DOI 
https://doi.org/10.1124/dmd.112.046342
PubMed 
23065531

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 9, 2012
  • Accepted October 11, 2012
  • Published online December 20, 2012.

Article Versions

  • Earlier version (October 12, 2012 - 07:15).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Marie-Anne Peyronneau,
  2. Wadad Saba,
  3. Sébastien Goutal,
  4. Annelaure Damont,
  5. Frédéric Dollé,
  6. Michael Kassiou,
  7. Michel Bottlaender, and
  8. Héric Valette
  1. Service Hospitalier Frédéric Joliot, CEA, Orsay, France (MA.P., W.S., S.G., A.D., F.D., M.B., H.V); and Brain and Mind Research Institute, School of Chemistry, and Discipline of Medical Radiation Sciences, University of Sydney, Sydney, New South Wales, Australia (M.K.)
  1. Address correspondence to:
    Marie-Anne Peyronneau, CEA, DSV, I2BM, Service Hospitalier Frédéric Joliot, 4 Place du Général Leclerc, 91406 Orsay, France. E-mail: marie-anne.schollhorn{at}cea.fr
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Drug Metabolism and Disposition: 41 (1)
Drug Metabolism and Disposition
Vol. 41, Issue 1
1 Jan 2013
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Research ArticleArticle

Metabolism of [18F]DPA-714 in Rodents and Nonhuman Primates

Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
Drug Metabolism and Disposition January 1, 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342

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Research ArticleArticle

Metabolism of [18F]DPA-714 in Rodents and Nonhuman Primates

Marie-Anne Peyronneau, Wadad Saba, Sébastien Goutal, Annelaure Damont, Frédéric Dollé, Michael Kassiou, Michel Bottlaender and Héric Valette
Drug Metabolism and Disposition January 1, 2013, 41 (1) 122-131; DOI: https://doi.org/10.1124/dmd.112.046342
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