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Index by author

October 01, 2013; Volume 41,Issue 10

A

  1. Alexandre, Eliane

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

B

  1. Bakhsheshian, Joshua

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  2. Barr, John T.

    1. Evaluation of Rhesus Monkey and Guinea Pig Hepatic Cytosol Fractions as Models for Human Aldehyde Oxidase
      Kanika V. Choughule, John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition October 2013, 41 (10) 1852-1858; DOI: https://doi.org/10.1124/dmd.113.052985

  3. Bates, Susan E.

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  4. Beedanagari, Sudheer

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157

  5. Benson, Eric A.

    1. Incubation of Whole Blood at Room Temperature Does Not Alter the Plasma Concentrations of MicroRNA-16 and -223
      Eric A. Benson and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1778-1781; DOI: https://doi.org/10.1124/dmd.113.052357

  6. Beumer, Jan H.

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

  7. Bush, Kevin T.

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

C

  1. Calinski, Diane

    1. The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir
      Hsia-lien Lin, Jaime D’Agostino, Cesar Kenaan, Diane Calinski and Paul F. Hollenberg
      Drug Metabolism and Disposition October 2013, 41 (10) 1813-1824; DOI: https://doi.org/10.1124/dmd.113.053108

  2. Chen, Jin-Qiu

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  3. Choughule, Kanika V.

    1. Evaluation of Rhesus Monkey and Guinea Pig Hepatic Cytosol Fractions as Models for Human Aldehyde Oxidase
      Kanika V. Choughule, John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition October 2013, 41 (10) 1852-1858; DOI: https://doi.org/10.1124/dmd.113.052985

  4. Christner, Susan M.

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

D

  1. D’Agostino, Jaime

    1. The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir
      Hsia-lien Lin, Jaime D’Agostino, Cesar Kenaan, Diane Calinski and Paul F. Hollenberg
      Drug Metabolism and Disposition October 2013, 41 (10) 1813-1824; DOI: https://doi.org/10.1124/dmd.113.053108

  2. Desta, Zeruesenay

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  3. Di, Li

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  4. Ding, Xinxin

    1. Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism
      Chunja Lee, Xinxin Ding and David S. Riddick
      Drug Metabolism and Disposition October 2013, 41 (10) 1782-1786; DOI: https://doi.org/10.1124/dmd.113.052993

  5. Dombkowski, Alan

    1. Insights into Insulin-Mediated Regulation of CYP2E1: miR-132/-212 Targeting of CYP2E1 and Role of Phosphatidylinositol 3-Kinase, Akt (Protein Kinase B), Mammalian Target of Rapamycin Signaling in Regulating miR-132/-212 and miR-122/-181a Expression in Primary Cultured Rat Hepatocytes
      Upasana Shukla, Nithin Tumma, Theresa Gratsch, Alan Dombkowski and Raymond F. Novak
      Drug Metabolism and Disposition October 2013, 41 (10) 1769-1777; DOI: https://doi.org/10.1124/dmd.113.052860

E

  1. Eraly, Satish A.

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

F

  1. Feng, Chenchen

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  2. Flockhart, David A.

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  3. Fu, Cexiong

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  4. Fukami, Tatsuki

    1. Epigenetic Regulation Is a Crucial Factor in the Repression of UGT1A1 Expression in the Human Kidney
      Shingo Oda, Tatsuki Fukami, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2013, 41 (10) 1738-1743; DOI: https://doi.org/10.1124/dmd.113.051201

G

  1. Gaedigk, Andrea

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  2. Gao, Man

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  3. Gong, Likun

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  4. Goswami, Chirayu

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  5. Gottesman, Michael M.

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  6. Gramignoli, Roberto

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

  7. Gratsch, Theresa

    1. Insights into Insulin-Mediated Regulation of CYP2E1: miR-132/-212 Targeting of CYP2E1 and Role of Phosphatidylinositol 3-Kinase, Akt (Protein Kinase B), Mammalian Target of Rapamycin Signaling in Regulating miR-132/-212 and miR-122/-181a Expression in Primary Cultured Rat Hepatocytes
      Upasana Shukla, Nithin Tumma, Theresa Gratsch, Alan Dombkowski and Raymond F. Novak
      Drug Metabolism and Disposition October 2013, 41 (10) 1769-1777; DOI: https://doi.org/10.1124/dmd.113.052860

H

  1. Hall, Matthew D.

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  2. Han, Xiaogang

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  3. Hankinson, Oliver

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157

  4. Herrmann, Michelle A.

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  5. Hewitt, Philip G.

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  6. Hollenberg, Paul F.

    1. The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir
      Hsia-lien Lin, Jaime D’Agostino, Cesar Kenaan, Diane Calinski and Paul F. Hollenberg
      Drug Metabolism and Disposition October 2013, 41 (10) 1813-1824; DOI: https://doi.org/10.1124/dmd.113.053108

  7. Hu, Yongjun

    1. Impact of Peptide Transporter 1 on the Intestinal Absorption and Pharmacokinetics of Valacyclovir after Oral Dose Escalation in Wild-Type and PepT1 Knockout Mice
      Bei Yang, Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition October 2013, 41 (10) 1867-1874; DOI: https://doi.org/10.1124/dmd.113.052597

  8. Hu, Zihua

    1. Small Nucleolar RNA-Derived MicroRNA hsa-miR-1291 Modulates Cellular Drug Disposition through Direct Targeting of ABC Transporter ABCC1
      Yu-Zhuo Pan, Amy Zhou, Zihua Hu and Ai-Ming Yu
      Drug Metabolism and Disposition October 2013, 41 (10) 1744-1751; DOI: https://doi.org/10.1124/dmd.113.052092

I

  1. Ingelman-Sundberg, Magnus

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157

  2. Izumi, Saki

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

J

  1. Jamshidi, Neema

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

  2. Jones, Jeffrey P.

    1. Evaluation of Rhesus Monkey and Guinea Pig Hepatic Cytosol Fractions as Models for Human Aldehyde Oxidase
      Kanika V. Choughule, John T. Barr and Jeffrey P. Jones
      Drug Metabolism and Disposition October 2013, 41 (10) 1852-1858; DOI: https://doi.org/10.1124/dmd.113.052985

K

  1. Kaddoumi, Amal

    1. In Vitro Investigation of Amyloid-β Hepatobiliary Disposition in Sandwich-Cultured Primary Rat Hepatocytes
      Loqman A. Mohamed and Amal Kaddoumi
      Drug Metabolism and Disposition October 2013, 41 (10) 1787-1796; DOI: https://doi.org/10.1124/dmd.113.052514

  2. Kenaan, Cesar

    1. The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir
      Hsia-lien Lin, Jaime D’Agostino, Cesar Kenaan, Diane Calinski and Paul F. Hollenberg
      Drug Metabolism and Disposition October 2013, 41 (10) 1813-1824; DOI: https://doi.org/10.1124/dmd.113.053108

  3. Klein, Kathrin

    1. Expression Variability of Absorption, Distribution, Metabolism, Excretion–Related MicroRNAs in Human Liver: Influence of Nongenetic Factors and Association with Gene Expression
      Jessica K. Rieger, Kathrin Klein, Stefan Winter and Ulrich M. Zanger
      Drug Metabolism and Disposition October 2013, 41 (10) 1752-1762; DOI: https://doi.org/10.1124/dmd.113.052126

  4. Komori, Takafumi

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

  5. Kopp-Schneider, Annette

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  6. Kume, Toshiyuki

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  7. Kusano, Kazutomi

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

  8. Kusuhara, Hiroyuki

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

L

  1. Lee, Chunja

    1. Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism
      Chunja Lee, Xinxin Ding and David S. Riddick
      Drug Metabolism and Disposition October 2013, 41 (10) 1782-1786; DOI: https://doi.org/10.1124/dmd.113.052993

  2. Leeder, J. Steven

    1. Epigenetic Regulation of ADME-Related Genes: Focus on Drug Metabolism and Transport
      Xiao-bo Zhong and J. Steven Leeder
      Drug Metabolism and Disposition October 2013, 41 (10) 1721-1724; DOI: https://doi.org/10.1124/dmd.113.053942

  3. Li, Chenggang

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  4. Li, Lang

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  5. Lin, Hai

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  6. Lin, Hsia-lien

    1. The Effect of Ritonavir on Human CYP2B6 Catalytic Activity: Heme Modification Contributes to the Mechanism-Based Inactivation of CYP2B6 and CYP3A4 by Ritonavir
      Hsia-lien Lin, Jaime D’Agostino, Cesar Kenaan, Diane Calinski and Paul F. Hollenberg
      Drug Metabolism and Disposition October 2013, 41 (10) 1813-1824; DOI: https://doi.org/10.1124/dmd.113.053108

  7. Liu, Henry C.

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

  8. Liu, Mingxia

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  9. Liu, Yunlong

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  10. Lukas, Arno

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

M

  1. Maeda, Kazuya

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

  2. Miao, Lingling

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  3. Moenks, Konrad

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  4. Mohamed, Loqman A.

    1. In Vitro Investigation of Amyloid-β Hepatobiliary Disposition in Sandwich-Cultured Primary Rat Hepatocytes
      Loqman A. Mohamed and Amal Kaddoumi
      Drug Metabolism and Disposition October 2013, 41 (10) 1787-1796; DOI: https://doi.org/10.1124/dmd.113.052514

  5. Mueller, Stefan O.

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

N

  1. Nakajima, Miki

    1. Epigenetic Regulation Is a Crucial Factor in the Repression of UGT1A1 Expression in the Human Kidney
      Shingo Oda, Tatsuki Fukami, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2013, 41 (10) 1738-1743; DOI: https://doi.org/10.1124/dmd.113.051201

  2. Nigam, Sanjay K.

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

  3. Novak, Raymond F.

    1. Insights into Insulin-Mediated Regulation of CYP2E1: miR-132/-212 Targeting of CYP2E1 and Role of Phosphatidylinositol 3-Kinase, Akt (Protein Kinase B), Mammalian Target of Rapamycin Signaling in Regulating miR-132/-212 and miR-122/-181a Expression in Primary Cultured Rat Hepatocytes
      Upasana Shukla, Nithin Tumma, Theresa Gratsch, Alan Dombkowski and Raymond F. Novak
      Drug Metabolism and Disposition October 2013, 41 (10) 1769-1777; DOI: https://doi.org/10.1124/dmd.113.052860

  4. Nozaki, Yoshitane

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

O

  1. Obach, R. Scott

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  2. Oda, Shingo

    1. Epigenetic Regulation Is a Crucial Factor in the Repression of UGT1A1 Expression in the Human Kidney
      Shingo Oda, Tatsuki Fukami, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2013, 41 (10) 1738-1743; DOI: https://doi.org/10.1124/dmd.113.051201

  3. Ohtsuka, Tatsuyuki

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  4. Osawa, Yoichi

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157

P

  1. Palsson, Bernhard O.

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

  2. Pan, Yu-Zhuo

    1. Small Nucleolar RNA-Derived MicroRNA hsa-miR-1291 Modulates Cellular Drug Disposition through Direct Targeting of ABC Transporter ABCC1
      Yu-Zhuo Pan, Amy Zhou, Zihua Hu and Ai-Ming Yu
      Drug Metabolism and Disposition October 2013, 41 (10) 1744-1751; DOI: https://doi.org/10.1124/dmd.113.052092

  3. Parise, Robert A.

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

  4. Parmentier, Céline

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  5. Peng, Lai

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157

  6. Philips, Santosh

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  7. Pillai, Venkateswaran C.

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

Q

  1. Qi, Xinming

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

R

  1. Ramamoorthy, Anuradha

    1. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  2. Ren, Jin

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  3. Richert, Lysiane

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  4. Riddick, David S.

    1. Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism
      Chunja Lee, Xinxin Ding and David S. Riddick
      Drug Metabolism and Disposition October 2013, 41 (10) 1782-1786; DOI: https://doi.org/10.1124/dmd.113.052993

  5. Rieger, Jessica K.

    1. Expression Variability of Absorption, Distribution, Metabolism, Excretion–Related MicroRNAs in Human Liver: Influence of Nongenetic Factors and Association with Gene Expression
      Jessica K. Rieger, Kathrin Klein, Stefan Winter and Ulrich M. Zanger
      Drug Metabolism and Disposition October 2013, 41 (10) 1752-1762; DOI: https://doi.org/10.1124/dmd.113.052126

  6. Robey, Robert W.

    1. Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2
      Joshua Bakhsheshian, Matthew D. Hall, Robert W. Robey, Michelle A. Herrmann, Jin-Qiu Chen, Susan E. Bates and Michael M. Gottesman
      Drug Metabolism and Disposition October 2013, 41 (10) 1805-1812; DOI: https://doi.org/10.1124/dmd.113.053140

  7. Rudek, Michelle A.

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

S

  1. Shukla, Upasana

    1. Insights into Insulin-Mediated Regulation of CYP2E1: miR-132/-212 Targeting of CYP2E1 and Role of Phosphatidylinositol 3-Kinase, Akt (Protein Kinase B), Mammalian Target of Rapamycin Signaling in Regulating miR-132/-212 and miR-122/-181a Expression in Primary Cultured Rat Hepatocytes
      Upasana Shukla, Nithin Tumma, Theresa Gratsch, Alan Dombkowski and Raymond F. Novak
      Drug Metabolism and Disposition October 2013, 41 (10) 1769-1777; DOI: https://doi.org/10.1124/dmd.113.052860

  2. Skaar, Todd C.

    1. Incubation of Whole Blood at Room Temperature Does Not Alter the Plasma Concentrations of MicroRNA-16 and -223
      Eric A. Benson and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1778-1781; DOI: https://doi.org/10.1124/dmd.113.052357
    2. Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
      Anuradha Ramamoorthy, Yunlong Liu, Santosh Philips, Zeruesenay Desta, Hai Lin, Chirayu Goswami, Andrea Gaedigk, Lang Li, David A. Flockhart and Todd C. Skaar
      Drug Metabolism and Disposition October 2013, 41 (10) 1763-1768; DOI: https://doi.org/10.1124/dmd.113.052886

  3. Smith, David E.

    1. Impact of Peptide Transporter 1 on the Intestinal Absorption and Pharmacokinetics of Valacyclovir after Oral Dose Escalation in Wild-Type and PepT1 Knockout Mice
      Bei Yang, Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition October 2013, 41 (10) 1867-1874; DOI: https://doi.org/10.1124/dmd.113.052597

  4. Snyder, Mark

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  5. Soderstrom, Cathy

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  6. Stanzel, Sven

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  7. Strom, Stephen C.

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

  8. Sugiyama, Yuichi

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

T

  1. Takahashi, Tsuyoshi

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  2. Takenaka, Osamu

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

  3. Tatekawa, Ichiro

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  4. Troutman, Matthew D.

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  5. Truisi, Germaine L.

    1. Transcriptomic Hepatotoxicity Signature of Chlorpromazine after Short- and Long-Term Exposure in Primary Human Sandwich Cultures
      Céline Parmentier, Germaine L. Truisi, Konrad Moenks, Sven Stanzel, Arno Lukas, Annette Kopp-Schneider, Eliane Alexandre, Philip G. Hewitt, Stefan O. Mueller and Lysiane Richert
      Drug Metabolism and Disposition October 2013, 41 (10) 1835-1842; DOI: https://doi.org/10.1124/dmd.113.052415

  6. Tumma, Nithin

    1. Insights into Insulin-Mediated Regulation of CYP2E1: miR-132/-212 Targeting of CYP2E1 and Role of Phosphatidylinositol 3-Kinase, Akt (Protein Kinase B), Mammalian Target of Rapamycin Signaling in Regulating miR-132/-212 and miR-122/-181a Expression in Primary Cultured Rat Hepatocytes
      Upasana Shukla, Nithin Tumma, Theresa Gratsch, Alan Dombkowski and Raymond F. Novak
      Drug Metabolism and Disposition October 2013, 41 (10) 1769-1777; DOI: https://doi.org/10.1124/dmd.113.052860

U

  1. Uno, Yasuhiro

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  2. Utoh, Masahiro

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

V

  1. Venkataramanan, Raman

    1. Ritonavir and Efavirenz Significantly Alter the Metabolism of Erlotinib—an Observation in Primary Cultures of Human Hepatocytes That Is Relevant to HIV Patients with Cancer
      Venkateswaran C. Pillai, Raman Venkataramanan, Robert A. Parise, Susan M. Christner, Roberto Gramignoli, Stephen C. Strom, Michelle A. Rudek and Jan H. Beumer
      Drug Metabolism and Disposition October 2013, 41 (10) 1843-1851; DOI: https://doi.org/10.1124/dmd.113.052100

W

  1. Wang, Yizheng

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  2. Winter, Stefan

    1. Expression Variability of Absorption, Distribution, Metabolism, Excretion–Related MicroRNAs in Human Liver: Influence of Nongenetic Factors and Association with Gene Expression
      Jessica K. Rieger, Kathrin Klein, Stefan Winter and Ulrich M. Zanger
      Drug Metabolism and Disposition October 2013, 41 (10) 1752-1762; DOI: https://doi.org/10.1124/dmd.113.052126

  3. Wu, Wei

    1. Multispecific Drug Transporter Slc22a8 (Oat3) Regulates Multiple Metabolic and Signaling Pathways
      Wei Wu, Neema Jamshidi, Satish A. Eraly, Henry C. Liu, Kevin T. Bush, Bernhard O. Palsson and Sanjay K. Nigam
      Drug Metabolism and Disposition October 2013, 41 (10) 1825-1834; DOI: https://doi.org/10.1124/dmd.113.052647

X

  1. Xie, Xiaofeng

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

Y

  1. Yamazaki, Hiroshi

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  2. Yang, Bei

    1. Impact of Peptide Transporter 1 on the Intestinal Absorption and Pharmacokinetics of Valacyclovir after Oral Dose Escalation in Wild-Type and PepT1 Knockout Mice
      Bei Yang, Yongjun Hu and David E. Smith
      Drug Metabolism and Disposition October 2013, 41 (10) 1867-1874; DOI: https://doi.org/10.1124/dmd.113.052597

  3. Yao, Jun

    1. Role of Multiple MicroRNAs in the Sexually Dimorphic Expression of Cyp2b9 in Mouse Liver
      Xiaofeng Xie, Lingling Miao, Jun Yao, Chenchen Feng, Chenggang Li, Man Gao, Mingxia Liu, Likun Gong, Yizheng Wang, Xinming Qi and Jin Ren
      Drug Metabolism and Disposition October 2013, 41 (10) 1732-1737; DOI: https://doi.org/10.1124/dmd.113.052217

  4. Yokoi, Tsuyoshi

    1. Epigenetic Regulation Is a Crucial Factor in the Repression of UGT1A1 Expression in the Human Kidney
      Shingo Oda, Tatsuki Fukami, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2013, 41 (10) 1738-1743; DOI: https://doi.org/10.1124/dmd.113.051201

  5. Yoshikawa, Takahiro

    1. Pitavastatin as an In Vivo Probe for Studying Hepatic Organic Anion Transporting Polypeptide-Mediated Drug–Drug Interactions in Cynomolgus Monkeys
      Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Takahiro Yoshikawa, Ichiro Tatekawa, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume
      Drug Metabolism and Disposition October 2013, 41 (10) 1875-1882; DOI: https://doi.org/10.1124/dmd.113.052753

  6. Yoshimura, Tsutomu

    1. Substrate-Dependent Inhibition of Organic Anion Transporting Polypeptide 1B1: Comparative Analysis with Prototypical Probe Substrates Estradiol-17β-Glucuronide, Estrone-3-Sulfate, and Sulfobromophthalein
      Saki Izumi, Yoshitane Nozaki, Takafumi Komori, Kazuya Maeda, Osamu Takenaka, Kazutomi Kusano, Tsutomu Yoshimura, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2013, 41 (10) 1859-1866; DOI: https://doi.org/10.1124/dmd.113.052290

  7. Yu, Ai-Ming

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157
    2. Small Nucleolar RNA-Derived MicroRNA hsa-miR-1291 Modulates Cellular Drug Disposition through Direct Targeting of ABC Transporter ABCC1
      Yu-Zhuo Pan, Amy Zhou, Zihua Hu and Ai-Ming Yu
      Drug Metabolism and Disposition October 2013, 41 (10) 1744-1751; DOI: https://doi.org/10.1124/dmd.113.052092

Z

  1. Zanger, Ulrich M.

    1. Expression Variability of Absorption, Distribution, Metabolism, Excretion–Related MicroRNAs in Human Liver: Influence of Nongenetic Factors and Association with Gene Expression
      Jessica K. Rieger, Kathrin Klein, Stefan Winter and Ulrich M. Zanger
      Drug Metabolism and Disposition October 2013, 41 (10) 1752-1762; DOI: https://doi.org/10.1124/dmd.113.052126

  2. Zhang, Hui

    1. Aldehyde Oxidase 1 (AOX1) in Human Liver Cytosols: Quantitative Characterization of AOX1 Expression Level and Activity Relationship
      Cexiong Fu, Li Di, Xiaogang Han, Cathy Soderstrom, Mark Snyder, Matthew D. Troutman, R. Scott Obach and Hui Zhang
      Drug Metabolism and Disposition October 2013, 41 (10) 1797-1804; DOI: https://doi.org/10.1124/dmd.113.053082

  3. Zhong, Xiao-Bo

    1. Potential Role of Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport
      Magnus Ingelman-Sundberg, Xiao-Bo Zhong, Oliver Hankinson, Sudheer Beedanagari, Ai-Ming Yu, Lai Peng and Yoichi Osawa
      Drug Metabolism and Disposition October 2013, 41 (10) 1725-1731; DOI: https://doi.org/10.1124/dmd.113.053157

  4. Zhong, Xiao-bo

    1. Epigenetic Regulation of ADME-Related Genes: Focus on Drug Metabolism and Transport
      Xiao-bo Zhong and J. Steven Leeder
      Drug Metabolism and Disposition October 2013, 41 (10) 1721-1724; DOI: https://doi.org/10.1124/dmd.113.053942

  5. Zhou, Amy

    1. Small Nucleolar RNA-Derived MicroRNA hsa-miR-1291 Modulates Cellular Drug Disposition through Direct Targeting of ABC Transporter ABCC1
      Yu-Zhuo Pan, Amy Zhou, Zihua Hu and Ai-Ming Yu
      Drug Metabolism and Disposition October 2013, 41 (10) 1744-1751; DOI: https://doi.org/10.1124/dmd.113.052092
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