Table of Contents

Articles

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  Characterization of Monocarboxylate Transporter 6: Expression in Human Intestine and Transport of the Antidiabetic Drug Nateglinide

  Noriko Kohyama, Hisae Shiokawa, Masayuki Ohbayashi, Yasuna Kobayashi and Toshinori Yamamoto

  Drug Metabolism and Disposition November 2013, 41 (11) 1883-1887; DOI: https://doi.org/10.1124/dmd.113.051854
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  Different Hydrolases Involved in Bioactivation of Prodrug-Type Angiotensin Receptor Blockers: Carboxymethylenebutenolidase and Carboxylesterase 1

  Tomoko Ishizuka, Yasushi Yoshigae, Nobuyuki Murayama and Takashi Izumi

  Drug Metabolism and Disposition November 2013, 41 (11) 1888-1895; DOI: https://doi.org/10.1124/dmd.113.053595
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  Relationship between CYP1A2 Localization and Lipid Microdomain Formation as a Function of Lipid Composition

  Lauren M. Brignac-Huber, James R. Reed, Marilyn K. Eyer and Wayne L. Backes

  Drug Metabolism and Disposition November 2013, 41 (11) 1896-1905; DOI: https://doi.org/10.1124/dmd.113.053611
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  The Letrozole Phase 1 Metabolite Carbinol as a Novel Probe Drug for UGT2B7

  Jana C. Precht, Werner Schroth, Kathrin Klein, Hiltrud Brauch, Evgeny Krynetskiy, Matthias Schwab and Thomas E. Mürdter

  Drug Metabolism and Disposition November 2013, 41 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.113.053405
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  Identification and Characterization of Psoralen and Isopsoralen as Potent CYP1A2 Reversible and Time-Dependent Inhibitors in Human and Rat Preclinical Studies

  Xiao-Mei Zhuang, Yu-Huan Zhong, Wei-Bin Xiao, Hua Li and Chuang Lu

  Drug Metabolism and Disposition November 2013, 41 (11) 1914-1922; DOI: https://doi.org/10.1124/dmd.113.053199
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  The Nonenzymatic Reactivity of the Acyl-Linked Metabolites of Mefenamic Acid toward Amino and Thiol Functional Group Bionucleophiles

  Howard Horng and Leslie Z. Benet

  Drug Metabolism and Disposition November 2013, 41 (11) 1923-1933; DOI: https://doi.org/10.1124/dmd.113.053223
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  Expression of Efflux Transporters in Human Ocular Tissues

  Peng Chen, Hao Chen, Xinjie Zang, Min Chen, Haoran Jiang, Shasha Han and Xianggen Wu

  Drug Metabolism and Disposition November 2013, 41 (11) 1934-1948; DOI: https://doi.org/10.1124/dmd.113.052704
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  Determination of Intracellular Unbound Concentrations and Subcellular Localization of Drugs in Rat Sandwich-Cultured Hepatocytes Compared with Liver Tissue

  Nathan D. Pfeifer, Kevin B. Harris, Grace Zhixia Yan and Kim L. R. Brouwer

  Drug Metabolism and Disposition November 2013, 41 (11) 1949-1956; DOI: https://doi.org/10.1124/dmd.113.052134
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  A Pharmacometric Approach to Investigate the Impact of Methylxanthine Abstinence and Caffeine Consumption on CYP1A2 Activity

  Vidya Perera, Annette S. Gross, Alan Forrest, Cornelia B. Landersdorfer, Hongmei Xu, Sihem Ait-Oudhia and Andrew J. McLachlan

  Drug Metabolism and Disposition November 2013, 41 (11) 1957-1966; DOI: https://doi.org/10.1124/dmd.113.053074
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  Metformin Sinusoidal Efflux from the Liver Is Consistent with Negligible Biliary Excretion and Absence of Enterohepatic Cycling

  Maciej J. Zamek-Gliszczynski, Jing Q. Bao, Jeffrey S. Day and J. William Higgins

  Drug Metabolism and Disposition November 2013, 41 (11) 1967-1971; DOI: https://doi.org/10.1124/dmd.113.053025