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Research ArticleArticle

Metformin Sinusoidal Efflux from the Liver Is Consistent with Negligible Biliary Excretion and Absence of Enterohepatic Cycling

Maciej J. Zamek-Gliszczynski, Jing Q. Bao, Jeffrey S. Day and J. William Higgins
Drug Metabolism and Disposition November 2013, 41 (11) 1967-1971; DOI: https://doi.org/10.1124/dmd.113.053025

Article Information

vol. 41 no. 11 1967-1971
DOI 
https://doi.org/10.1124/dmd.113.053025
PubMed 
24009308
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 22, 2013
  • Accepted September 5, 2013
  • Published online October 16, 2013.

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Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Maciej J. Zamek-Gliszczynski,
  2. Jing Q. Bao,
  3. Jeffrey S. Day, and
  4. J. William Higgins
  1. Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana
  1. Address correspondence to:
    Dr. Maciej J. Zamek-Gliszczynski, Drug Disposition, Lilly Research Laboratories Lilly Corporate Center, Indianapolis, IN 46285. E-mail: m_zamek-gliszczynski{at}lilly.com
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Low Metformin Biliary Excretion Due to Sinusoidal Efflux

Maciej J. Zamek-Gliszczynski, Jing Q. Bao, Jeffrey S. Day and J. William Higgins
Drug Metabolism and Disposition November 1, 2013, 41 (11) 1967-1971; DOI: https://doi.org/10.1124/dmd.113.053025
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