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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

February 01, 2013; Volume 41,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Ainslie, Garrett R.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  2. Aleksunes, Lauren M.

    1. You have access
      Down-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant Mice
      Lindsay L. Yacovino, Christopher J. Gibson and Lauren M. Aleksunes
      Drug Metabolism and Disposition February 2013, 41 (2) 320-325; DOI: https://doi.org/10.1124/dmd.112.047092
    2. You have access
      Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain
      Marie C. Fortin, Lauren M. Aleksunes and Jason R. Richardson
      Drug Metabolism and Disposition February 2013, 41 (2) 326-331; DOI: https://doi.org/10.1124/dmd.112.049395
  3. Aliño, Salvador F.

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  4. Amin, Neeta

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
  5. Arias, Agostina

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  6. Augustin, Ewa

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  7. Avery, Lindsay B.

    1. You have access
      Compartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal Fluid
      Lindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601

B

  1. Bammler, Theo K.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  2. Banchio, Claudia

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  3. Bea, Sergio

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  4. Beyer, Richard P.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  5. Bonzo, Jessica A.

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  6. Bosó, Virginia

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  7. Bouic, Patrick J.

    1. You have access
      The Potential of Sutherlandia frutescens for Herb-Drug Interaction
      Pius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd Rosenkranz
      Drug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
  8. Boussery, Koen

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  9. Boykin, David W.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  10. Bridges, Arlene S.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  11. Budha, Nageshwar

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
  12. Bumpus, Namandjé N.

    1. You have access
      Compartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal Fluid
      Lindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601

C

  1. Callegari, Ernesto

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
  2. Caritis, Steve N.

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  3. Catania, Viviana A.

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  4. Chambers, Timothy C.

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  5. Chapman, John D.

    1. You have access
      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
      Ariel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
  6. Chen, Xiaoyan

    1. You have access
      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
  7. Cheng, Jie

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  8. Choi, Su-Young

    1. You have access
      Isoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and Progesterone
      Su-Young Choi, Kwi Hye Koh and Hyunyoung Jeong
      Drug Metabolism and Disposition February 2013, 41 (2) 263-269; DOI: https://doi.org/10.1124/dmd.112.046276
  9. Chu, Rong

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  10. Clarke, James D.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  11. Coulter, Sherry

    1. You have access
      RBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X Receptor
      Ritu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. Goldstein
      Drug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728

D

  1. Dai, Hongying

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  2. De Bock, Lies

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  3. Deng, Pan

    1. You have access
      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
  4. De Paepe, Peter

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  5. Diao, Xingxing

    1. You have access
      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
  6. Dickmann, Leslie J

    1. You have access
      Quantitative Prediction of CYP2B6 Induction by Estradiol During Pregnancy: Potential Explanation for Increased Methadone Clearance During Pregnancy
      Leslie J Dickmann and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 270-274; DOI: https://doi.org/10.1124/dmd.112.047118
  7. Ding, Xinxin

    1. You have access
      The Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-Methylcholanthrene
      Chunja Lee, Xinxin Ding and David S. Riddick
      Drug Metabolism and Disposition February 2013, 41 (2) 457-465; DOI: https://doi.org/10.1124/dmd.112.048835
    2. You have access
      Dietary Regulation of Mouse Intestinal P450 Expression and Drug Metabolism
      Peng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu Zhang
      Drug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
  8. Dorko, Kenneth

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891

E

  1. Ekström, Lena

    1. You have access
      Tissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human Fetus
      Lena Ekström, Maria Johansson and Anders Rane
      Drug Metabolism and Disposition February 2013, 41 (2) 291-295; DOI: https://doi.org/10.1124/dmd.112.049197
  2. Ellis, Ewa C. S.

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891

F

  1. Fang, Cheng

    1. You have access
      Dietary Regulation of Mouse Intestinal P450 Expression and Drug Metabolism
      Peng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu Zhang
      Drug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
  2. Farin, Frederico M.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  3. Fasinu, Pius S.

    1. You have access
      The Potential of Sutherlandia frutescens for Herb-Drug Interaction
      Pius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd Rosenkranz
      Drug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
  4. Fedejko-Kap, Barbara

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  5. Fidler, Trevor P.

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
  6. Fortin, Marie C.

    1. You have access
      Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain
      Marie C. Fortin, Lauren M. Aleksunes and Jason R. Richardson
      Drug Metabolism and Disposition February 2013, 41 (2) 326-331; DOI: https://doi.org/10.1124/dmd.112.049395
  7. Furuta, Takashi

    1. You have access
      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi Furuta
      Drug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561

G

  1. Galiana, María

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  2. Generaux, Claudia N.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  3. Generaux, Grant T.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  4. Gibson, Christopher J.

    1. You have access
      Down-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant Mice
      Lindsay L. Yacovino, Christopher J. Gibson and Lauren M. Aleksunes
      Drug Metabolism and Disposition February 2013, 41 (2) 320-325; DOI: https://doi.org/10.1124/dmd.112.047092
  5. Goldstein, Joyce A.

    1. You have access
      RBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X Receptor
      Ritu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. Goldstein
      Drug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
  6. Gonzalez, Frank J.

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  7. Goto, Mari

    1. You have access
      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi Furuta
      Drug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
  8. Gramignoli, Roberto

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  9. Grepper, Susan

    1. You have access
      Induction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell Lines
      Ioannis Papageorgiou, Susan Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015
  10. Grime, Ken

    1. You have access
      Species Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters Involvement
      Ken Grime and Stuart W. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 372-378; DOI: https://doi.org/10.1124/dmd.112.049312
  11. Gutmann, Heike

    1. You have access
      The Potential of Sutherlandia frutescens for Herb-Drug Interaction
      Pius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd Rosenkranz
      Drug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593

H

  1. Haley, Kathleen J.

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  2. Hansel, Marc

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  3. Harmon, Kelly A.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  4. Hebert, Mary F.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  5. Hendrix, Craig W.

    1. You have access
      Compartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal Fluid
      Lindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601
  6. Hernández, Julio

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  7. Herrero, María José

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  8. Hines, Ronald N.

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  9. Hisaka, Akihiro

    1. You have access
      Analysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic Enzymes
      Toshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi Ito
      Drug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460
  10. Hop, Cornelis E.C.A.

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
  11. Hosoda, Kaori

    1. You have access
      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi Furuta
      Drug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
  12. Humphreys, Joan E.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918

I

  1. Idle, Jeffrey R.

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  2. Ishii, Kazuo

    1. You have access
      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi Furuta
      Drug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
  3. Ismail, Mohamed A.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  4. Isoherranen, Nina

    1. You have access
      Drug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?
      Nina Isoherranen and Kenneth E. Thummel
      Drug Metabolism and Disposition February 2013, 41 (2) 256-262; DOI: https://doi.org/10.1124/dmd.112.050245
    2. You have access
      Quantitative Prediction of CYP2B6 Induction by Estradiol During Pregnancy: Potential Explanation for Increased Methadone Clearance During Pregnancy
      Leslie J Dickmann and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 270-274; DOI: https://doi.org/10.1124/dmd.112.047118
    3. You have access
      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
      Ariel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
  5. Ito, Kiyomi

    1. You have access
      Analysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic Enzymes
      Toshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi Ito
      Drug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460

J

  1. James, Alexander-David

    1. You have access
      The Potential of Sutherlandia frutescens for Herb-Drug Interaction
      Pius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd Rosenkranz
      Drug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
  2. Jeong, Hyunyoung

    1. You have access
      Isoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and Progesterone
      Su-Young Choi, Kwi Hye Koh and Hyunyoung Jeong
      Drug Metabolism and Disposition February 2013, 41 (2) 263-269; DOI: https://doi.org/10.1124/dmd.112.046276
  3. Jia, Kunzhi

    1. You have access
      Dietary Regulation of Mouse Intestinal P450 Expression and Drug Metabolism
      Peng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu Zhang
      Drug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
  4. Johansson, Maria

    1. You have access
      Tissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human Fetus
      Lena Ekström, Maria Johansson and Anders Rane
      Drug Metabolism and Disposition February 2013, 41 (2) 291-295; DOI: https://doi.org/10.1124/dmd.112.049197
  5. Johnson, Caroline H.

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  6. Johnson, Theodore R.

    1. You have access
      Prediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus Hepatocytes
      Jialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji Yamazaki
      Drug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114

K

  1. Kadam, Rajendra S.

    1. You have access
      RETRACTION: Immunohistochemical and Functional Characterization of Peptide, Organic Cation, Neutral and Basic Amino Acid, and Monocarboxylate Drug Transporters in Human Ocular Tissues
      Rajendra S. Kadam, Sunil K. Vooturi and Uday B. Kompella
      Drug Metabolism and Disposition February 2013, 41 (2) 466-474; DOI: https://doi.org/10.1124/dmd.112.045674
  2. Kalgutkar, Amit S.

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
  3. Kanaoka, Eri

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  4. Kang, Dong Wook

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  5. Kelly, Edward J.

    1. You have access
      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
      Ariel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
  6. Khojasteh, S. Cyrus

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
  7. Kinyamu, Harriet

    1. You have access
      RBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X Receptor
      Ritu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. Goldstein
      Drug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
  8. Kogayu, Motohiro

    1. You have access
      Application of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of Predictability
      Hiroyuki Sayama, Hiroshi Komura and Motohiro Kogayu
      Drug Metabolism and Disposition February 2013, 41 (2) 498-507; DOI: https://doi.org/10.1124/dmd.112.048819
  9. Koh, Kwi Hye

    1. You have access
      Isoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and Progesterone
      Su-Young Choi, Kwi Hye Koh and Hyunyoung Jeong
      Drug Metabolism and Disposition February 2013, 41 (2) 263-269; DOI: https://doi.org/10.1124/dmd.112.046276
  10. Kompella, Uday B.

    1. You have access
      RETRACTION: Immunohistochemical and Functional Characterization of Peptide, Organic Cation, Neutral and Basic Amino Acid, and Monocarboxylate Drug Transporters in Human Ocular Tissues
      Rajendra S. Kadam, Sunil K. Vooturi and Uday B. Kompella
      Drug Metabolism and Disposition February 2013, 41 (2) 466-474; DOI: https://doi.org/10.1124/dmd.112.045674
  11. Komura, Hiroshi

    1. You have access
      Application of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of Predictability
      Hiroyuki Sayama, Hiroshi Komura and Motohiro Kogayu
      Drug Metabolism and Disposition February 2013, 41 (2) 498-507; DOI: https://doi.org/10.1124/dmd.112.048819
  12. Krausz, Kristopher W.

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  13. Kudo, Toshiyuki

    1. You have access
      Analysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic Enzymes
      Toshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi Ito
      Drug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460

L

  1. Le, Huong N.

    1. You have access
      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
      Ariel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
  2. Lee, Chunja

    1. You have access
      The Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-Methylcholanthrene
      Chunja Lee, Xinxin Ding and David S. Riddick
      Drug Metabolism and Disposition February 2013, 41 (2) 457-465; DOI: https://doi.org/10.1124/dmd.112.048835
  3. Lee, Nora

    1. You have access
      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
      Ariel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
  4. Leeder, J. Steven

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  5. Li, Xiuli

    1. You have access
      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
  6. Luecke, Hans

    1. You have access
      Cytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized Mice
      Caroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
  7. Lyssikatos, Joseph

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019

M

  1. MacDonald, James W.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  2. Mao, Jialin

    1. You have access
      Prediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus Hepatocytes
      Jialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji Yamazaki
      Drug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114
  3. Mao, Qingcheng

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  4. Marqués, María Remedios

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  5. Marrero, Patricia

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  6. Mascitti, Vincent

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
  7. Mattison, Donald R.

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  8. Mazerska, Zofia

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  9. Miao, Zhuang

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
  10. Moore, Chad D.

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
  11. Mottino, Aldo D.

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  12. Mulder, Teresa

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
  13. Murai, Takahiro

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318

N

  1. Nucci, Gianluca

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551

O

  1. Orton, Christopher R.

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318

P

  1. Paine, Mary F.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  2. Paine, Stuart W.

    1. You have access
      Species Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters Involvement
      Ken Grime and Stuart W. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 372-378; DOI: https://doi.org/10.1124/dmd.112.049312
  3. Papageorgiou, Ioannis

    1. You have access
      Induction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell Lines
      Ioannis Papageorgiou, Susan Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015
  4. Pawlowska, Monika

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  5. Polli, Joseph W.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  6. Poveda, José Luis

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977

R

  1. Radominska-Pandya, Anna

    1. You have access
      Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
      Monika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. Chambers
      Drug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
  2. Rana, Ritu

    1. You have access
      RBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X Receptor
      Ritu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. Goldstein
      Drug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
  3. Rane, Anders

    1. You have access
      Tissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human Fetus
      Lena Ekström, Maria Johansson and Anders Rane
      Drug Metabolism and Disposition February 2013, 41 (2) 291-295; DOI: https://doi.org/10.1124/dmd.112.049197
  4. Reese, Melinda J.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  5. Reilly, Christopher A.

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
  6. Richardson, Jason R.

    1. You have access
      Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain
      Marie C. Fortin, Lauren M. Aleksunes and Jason R. Richardson
      Drug Metabolism and Disposition February 2013, 41 (2) 326-331; DOI: https://doi.org/10.1124/dmd.112.049395
  7. Riddick, David S.

    1. You have access
      The Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-Methylcholanthrene
      Chunja Lee, Xinxin Ding and David S. Riddick
      Drug Metabolism and Disposition February 2013, 41 (2) 457-465; DOI: https://doi.org/10.1124/dmd.112.048835
  8. Riffel, Amanda K.

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  9. Rigalli, Juan P.

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  10. Roberts, Jessica K.

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
  11. Rogiers, Xavier

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  12. Rosenkranz, Bernd

    1. You have access
      The Potential of Sutherlandia frutescens for Herb-Drug Interaction
      Pius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd Rosenkranz
      Drug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
  13. Rudewicz, Patrick J.

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
  14. Ruiz, María L.

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357

S

  1. Sánchez-Plumed, Jaime

    1. You have access
      Increased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285
      Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. Aliño
      Drug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
  2. Savina, Paul M.

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  3. Sayama, Hiroyuki

    1. You have access
      Application of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of Predictability
      Hiroyuki Sayama, Hiroshi Komura and Motohiro Kogayu
      Drug Metabolism and Disposition February 2013, 41 (2) 498-507; DOI: https://doi.org/10.1124/dmd.112.048819
  4. Schiller, Hilmar

    1. You have access
      The Potential of Sutherlandia frutescens for Herb-Drug Interaction
      Pius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd Rosenkranz
      Drug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
  5. Sharma, Raman

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
  6. Sharma, Shringi

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  7. Sharma, Sunita

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  8. Shen, Zhongzhou

    1. You have access
      Prediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus Hepatocytes
      Jialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji Yamazaki
      Drug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114
  9. Shibasaki, Hiromi

    1. You have access
      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi Furuta
      Drug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
  10. Shuster, Diana L.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  11. Sokal, Etienne

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  12. Solon, Eric

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
  13. Stephenne, Xavier

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  14. Strom, Stephen C.

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  15. Sugiyama, Yuichi

    1. You have access
      Analysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic Enzymes
      Toshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi Ito
      Drug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460
  16. Suzuki, Atsushi

    1. You have access
      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
      Hiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi Furuta
      Drug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561

T

  1. Tahan, Veysel

    1. You have access
      Hepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human Hepatocytes
      Shringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. Strom
      Drug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
  2. Tantisira, Kelan G.

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  3. Thakker, Dhiren R.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  4. Thummel, Kenneth E.

    1. You have access
      Drug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?
      Nina Isoherranen and Kenneth E. Thummel
      Drug Metabolism and Disposition February 2013, 41 (2) 256-262; DOI: https://doi.org/10.1124/dmd.112.050245
    2. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  5. Tidwell, Richard R.

    1. You have access
      Compartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal Prodrug
      Claudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. Paine
      Drug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
  6. Topletz, Ariel R.

    1. You have access
      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
      Ariel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina Isoherranen
      Drug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
  7. Tracey, Helen

    1. You have access
      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
      Melinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. Polli
      Drug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
  8. Tsai, Jesse M.

    1. You have access
      Gestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant Mice
      Diana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng Mao
      Drug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
  9. Tugnait, Meera

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
      Zhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551

U

  1. Unadkat, Jashvant D.

    1. You have access
      Induction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell Lines
      Ioannis Papageorgiou, Susan Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015

V

  1. VanAusdall, Jennifer L.

    1. You have access
      Compartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal Fluid
      Lindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601
  2. Van Bocxlaer, Jan

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  3. Van Winckel, Myriam

    1. You have access
      In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores
      Lies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van Bocxlaer
      Drug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
  4. Vaz, Alfin D.

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      Pharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male Subjects
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  6. Villanueva, Silvina

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      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
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      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  7. Vooturi, Sunil K.

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  8. Vore, Mary

    1. You have access
      Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
      María L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. Catania
      Drug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
  9. Vyhlidal, Carrie A.

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      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
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      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999

W

  1. Wang, Joanne

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      Hepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse Pregnancy
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  2. Ward, Robert M.

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      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
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      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
  3. Ware, Joseph A

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      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
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      In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
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  5. Weiss, Scott T.

    1. You have access
      Cotinine in Human Placenta Predicts Induction of Gene Expression in Fetal Tissues
      Carrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven Leeder
      Drug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
  6. Wong, Harvey

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019

X

  1. Xie, Cen

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      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684

Y

  1. Yacovino, Lindsay L.

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      Down-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant Mice
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      Drug Metabolism and Disposition February 2013, 41 (2) 320-325; DOI: https://doi.org/10.1124/dmd.112.047092
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      Intraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in Humans
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  4. Yost, Garold S.

    1. You have access
      Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
      Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. Yost
      Drug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
  5. Yue, Qin

    1. You have access
      Evaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-Thiadiazole
      Qin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019

Z

  1. Zhang, Peng

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      Dietary Regulation of Mouse Intestinal P450 Expression and Drug Metabolism
      Peng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu Zhang
      Drug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
  2. Zhang, Qing-Yu

    1. You have access
      Dietary Regulation of Mouse Intestinal P450 Expression and Drug Metabolism
      Peng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu Zhang
      Drug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
  3. Zhang, Yifan

    1. You have access
      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
  4. Zhong, Dafang

    1. You have access
      Metabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in Biotransformation
      Xingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan Chen
      Drug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
  5. Zhou, Xin

    1. You have access
      Dietary Regulation of Mouse Intestinal P450 Expression and Drug Metabolism
      Peng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu Zhang
      Drug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
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Drug Metabolism and Disposition: 41 (2)
Drug Metabolism and Disposition
Vol. 41, Issue 2
1 Feb 2013
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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