Index by author
February 01, 2013; Volume 41,Issue 2
A
Ainslie, Garrett R.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Aleksunes, Lauren M.
- You have accessDown-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant MiceLindsay L. Yacovino, Christopher J. Gibson and Lauren M. AleksunesDrug Metabolism and Disposition February 2013, 41 (2) 320-325; DOI: https://doi.org/10.1124/dmd.112.047092
- You have accessAlteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing BrainMarie C. Fortin, Lauren M. Aleksunes and Jason R. RichardsonDrug Metabolism and Disposition February 2013, 41 (2) 326-331; DOI: https://doi.org/10.1124/dmd.112.049395
Aliño, Salvador F.
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Amin, Neeta
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Arias, Agostina
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Augustin, Ewa
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Avery, Lindsay B.
- You have accessCompartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal FluidLindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601
B
Bammler, Theo K.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Banchio, Claudia
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Bea, Sergio
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Beyer, Richard P.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Bonzo, Jessica A.
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Bosó, Virginia
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Bouic, Patrick J.
- You have accessThe Potential of Sutherlandia frutescens for Herb-Drug InteractionPius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd RosenkranzDrug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
Boussery, Koen
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Boykin, David W.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Bridges, Arlene S.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Budha, Nageshwar
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Bumpus, Namandjé N.
- You have accessCompartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal FluidLindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601
C
Callegari, Ernesto
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Caritis, Steve N.
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Catania, Viviana A.
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Chambers, Timothy C.
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Chapman, John D.
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Chen, Xiaoyan
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
Cheng, Jie
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Choi, Su-Young
- You have accessIsoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and ProgesteroneSu-Young Choi, Kwi Hye Koh and Hyunyoung JeongDrug Metabolism and Disposition February 2013, 41 (2) 263-269; DOI: https://doi.org/10.1124/dmd.112.046276
Chu, Rong
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Clarke, James D.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Coulter, Sherry
- You have accessRBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X ReceptorRitu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. GoldsteinDrug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
D
Dai, Hongying
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
De Bock, Lies
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Deng, Pan
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
De Paepe, Peter
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Diao, Xingxing
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
Dickmann, Leslie J
- You have accessQuantitative Prediction of CYP2B6 Induction by Estradiol During Pregnancy: Potential Explanation for Increased Methadone Clearance During PregnancyLeslie J Dickmann and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 270-274; DOI: https://doi.org/10.1124/dmd.112.047118
Ding, Xinxin
- You have accessThe Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-MethylcholanthreneChunja Lee, Xinxin Ding and David S. RiddickDrug Metabolism and Disposition February 2013, 41 (2) 457-465; DOI: https://doi.org/10.1124/dmd.112.048835
- You have accessDietary Regulation of Mouse Intestinal P450 Expression and Drug MetabolismPeng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu ZhangDrug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
Dorko, Kenneth
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
E
Ekström, Lena
- You have accessTissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human FetusLena Ekström, Maria Johansson and Anders RaneDrug Metabolism and Disposition February 2013, 41 (2) 291-295; DOI: https://doi.org/10.1124/dmd.112.049197
Ellis, Ewa C. S.
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
F
Fang, Cheng
- You have accessDietary Regulation of Mouse Intestinal P450 Expression and Drug MetabolismPeng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu ZhangDrug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
Farin, Frederico M.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Fasinu, Pius S.
- You have accessThe Potential of Sutherlandia frutescens for Herb-Drug InteractionPius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd RosenkranzDrug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
Fedejko-Kap, Barbara
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Fidler, Trevor P.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
Fortin, Marie C.
- You have accessAlteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing BrainMarie C. Fortin, Lauren M. Aleksunes and Jason R. RichardsonDrug Metabolism and Disposition February 2013, 41 (2) 326-331; DOI: https://doi.org/10.1124/dmd.112.049395
Furuta, Takashi
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
G
Galiana, María
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Generaux, Claudia N.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Generaux, Grant T.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Gibson, Christopher J.
- You have accessDown-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant MiceLindsay L. Yacovino, Christopher J. Gibson and Lauren M. AleksunesDrug Metabolism and Disposition February 2013, 41 (2) 320-325; DOI: https://doi.org/10.1124/dmd.112.047092
Goldstein, Joyce A.
- You have accessRBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X ReceptorRitu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. GoldsteinDrug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
Gonzalez, Frank J.
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Goto, Mari
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
Gramignoli, Roberto
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Grepper, Susan
- You have accessInduction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell LinesIoannis Papageorgiou, Susan Grepper and Jashvant D. UnadkatDrug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015
Grime, Ken
- You have accessSpecies Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters InvolvementKen Grime and Stuart W. PaineDrug Metabolism and Disposition February 2013, 41 (2) 372-378; DOI: https://doi.org/10.1124/dmd.112.049312
Gutmann, Heike
- You have accessThe Potential of Sutherlandia frutescens for Herb-Drug InteractionPius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd RosenkranzDrug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
H
Haley, Kathleen J.
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
Hansel, Marc
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Harmon, Kelly A.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Hebert, Mary F.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Hendrix, Craig W.
- You have accessCompartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal FluidLindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601
Hernández, Julio
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Herrero, María José
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Hines, Ronald N.
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Hisaka, Akihiro
- You have accessAnalysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic EnzymesToshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi ItoDrug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460
Hop, Cornelis E.C.A.
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Hosoda, Kaori
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
Humphreys, Joan E.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
I
Idle, Jeffrey R.
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Ishii, Kazuo
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
Ismail, Mohamed A.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Isoherranen, Nina
- You have accessDrug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?Nina Isoherranen and Kenneth E. ThummelDrug Metabolism and Disposition February 2013, 41 (2) 256-262; DOI: https://doi.org/10.1124/dmd.112.050245
- You have accessQuantitative Prediction of CYP2B6 Induction by Estradiol During Pregnancy: Potential Explanation for Increased Methadone Clearance During PregnancyLeslie J Dickmann and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 270-274; DOI: https://doi.org/10.1124/dmd.112.047118
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Ito, Kiyomi
- You have accessAnalysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic EnzymesToshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi ItoDrug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460
J
James, Alexander-David
- You have accessThe Potential of Sutherlandia frutescens for Herb-Drug InteractionPius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd RosenkranzDrug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
Jeong, Hyunyoung
- You have accessIsoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and ProgesteroneSu-Young Choi, Kwi Hye Koh and Hyunyoung JeongDrug Metabolism and Disposition February 2013, 41 (2) 263-269; DOI: https://doi.org/10.1124/dmd.112.046276
Jia, Kunzhi
- You have accessDietary Regulation of Mouse Intestinal P450 Expression and Drug MetabolismPeng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu ZhangDrug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
Johansson, Maria
- You have accessTissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human FetusLena Ekström, Maria Johansson and Anders RaneDrug Metabolism and Disposition February 2013, 41 (2) 291-295; DOI: https://doi.org/10.1124/dmd.112.049197
Johnson, Caroline H.
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Johnson, Theodore R.
- You have accessPrediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus HepatocytesJialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji YamazakiDrug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114
K
Kadam, Rajendra S.
- You have accessRETRACTION: Immunohistochemical and Functional Characterization of Peptide, Organic Cation, Neutral and Basic Amino Acid, and Monocarboxylate Drug Transporters in Human Ocular TissuesRajendra S. Kadam, Sunil K. Vooturi and Uday B. KompellaDrug Metabolism and Disposition February 2013, 41 (2) 466-474; DOI: https://doi.org/10.1124/dmd.112.045674
Kalgutkar, Amit S.
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Kanaoka, Eri
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Kang, Dong Wook
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Kelly, Edward J.
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Khojasteh, S. Cyrus
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Kinyamu, Harriet
- You have accessRBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X ReceptorRitu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. GoldsteinDrug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
Kogayu, Motohiro
- You have accessApplication of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of PredictabilityHiroyuki Sayama, Hiroshi Komura and Motohiro KogayuDrug Metabolism and Disposition February 2013, 41 (2) 498-507; DOI: https://doi.org/10.1124/dmd.112.048819
Koh, Kwi Hye
- You have accessIsoform-Specific Regulation of Cytochromes P450 Expression by Estradiol and ProgesteroneSu-Young Choi, Kwi Hye Koh and Hyunyoung JeongDrug Metabolism and Disposition February 2013, 41 (2) 263-269; DOI: https://doi.org/10.1124/dmd.112.046276
Kompella, Uday B.
- You have accessRETRACTION: Immunohistochemical and Functional Characterization of Peptide, Organic Cation, Neutral and Basic Amino Acid, and Monocarboxylate Drug Transporters in Human Ocular TissuesRajendra S. Kadam, Sunil K. Vooturi and Uday B. KompellaDrug Metabolism and Disposition February 2013, 41 (2) 466-474; DOI: https://doi.org/10.1124/dmd.112.045674
Komura, Hiroshi
- You have accessApplication of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of PredictabilityHiroyuki Sayama, Hiroshi Komura and Motohiro KogayuDrug Metabolism and Disposition February 2013, 41 (2) 498-507; DOI: https://doi.org/10.1124/dmd.112.048819
Krausz, Kristopher W.
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Kudo, Toshiyuki
- You have accessAnalysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic EnzymesToshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi ItoDrug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460
L
Le, Huong N.
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Lee, Chunja
- You have accessThe Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-MethylcholanthreneChunja Lee, Xinxin Ding and David S. RiddickDrug Metabolism and Disposition February 2013, 41 (2) 457-465; DOI: https://doi.org/10.1124/dmd.112.048835
Lee, Nora
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Leeder, J. Steven
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
Li, Xiuli
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
Luecke, Hans
- You have accessCytochrome P450 Regulation by α-Tocopherol in Pxr-Null and PXR-Humanized MiceCaroline H. Johnson, Jessica A. Bonzo, Jie Cheng, Kristopher W. Krausz, Dong Wook Kang, Hans Luecke, Jeffrey R. Idle and Frank J. GonzalezDrug Metabolism and Disposition February 2013, 41 (2) 406-413; DOI: https://doi.org/10.1124/dmd.112.048009
Lyssikatos, Joseph
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
M
MacDonald, James W.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Mao, Jialin
- You have accessPrediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus HepatocytesJialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji YamazakiDrug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114
Mao, Qingcheng
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Marqués, María Remedios
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Marrero, Patricia
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Mascitti, Vincent
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Mattison, Donald R.
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Mazerska, Zofia
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Miao, Zhuang
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Moore, Chad D.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
Mottino, Aldo D.
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Mulder, Teresa
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Murai, Takahiro
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
N
Nucci, Gianluca
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
O
Orton, Christopher R.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
P
Paine, Mary F.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Paine, Stuart W.
- You have accessSpecies Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters InvolvementKen Grime and Stuart W. PaineDrug Metabolism and Disposition February 2013, 41 (2) 372-378; DOI: https://doi.org/10.1124/dmd.112.049312
Papageorgiou, Ioannis
- You have accessInduction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell LinesIoannis Papageorgiou, Susan Grepper and Jashvant D. UnadkatDrug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015
Pawlowska, Monika
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Polli, Joseph W.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Poveda, José Luis
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
R
Radominska-Pandya, Anna
- You have accessMetabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical UseMonika Pawlowska, Rong Chu, Barbara Fedejko-Kap, Ewa Augustin, Zofia Mazerska, Anna Radominska-Pandya and Timothy C. ChambersDrug Metabolism and Disposition February 2013, 41 (2) 414-421; DOI: https://doi.org/10.1124/dmd.112.047811
Rana, Ritu
- You have accessRBCK1, an E3 Ubiquitin Ligase, Interacts with and Ubiquinates the Human Pregnane X ReceptorRitu Rana, Sherry Coulter, Harriet Kinyamu and Joyce A. GoldsteinDrug Metabolism and Disposition February 2013, 41 (2) 398-405; DOI: https://doi.org/10.1124/dmd.112.048728
Rane, Anders
- You have accessTissue Distribution and Relative Gene Expression of UDP-Glucuronosyltransferases (2B7, 2B15, 2B17) in the Human FetusLena Ekström, Maria Johansson and Anders RaneDrug Metabolism and Disposition February 2013, 41 (2) 291-295; DOI: https://doi.org/10.1124/dmd.112.049197
Reese, Melinda J.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Reilly, Christopher A.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
Richardson, Jason R.
- You have accessAlteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing BrainMarie C. Fortin, Lauren M. Aleksunes and Jason R. RichardsonDrug Metabolism and Disposition February 2013, 41 (2) 326-331; DOI: https://doi.org/10.1124/dmd.112.049395
Riddick, David S.
- You have accessThe Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-MethylcholanthreneChunja Lee, Xinxin Ding and David S. RiddickDrug Metabolism and Disposition February 2013, 41 (2) 457-465; DOI: https://doi.org/10.1124/dmd.112.048835
Riffel, Amanda K.
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
Rigalli, Juan P.
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Roberts, Jessica K.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
Rogiers, Xavier
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Rosenkranz, Bernd
- You have accessThe Potential of Sutherlandia frutescens for Herb-Drug InteractionPius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd RosenkranzDrug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
Rudewicz, Patrick J.
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Ruiz, María L.
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
S
Sánchez-Plumed, Jaime
- You have accessIncreased Hospital Stay and Allograft Disfunction in Renal Transplant Recipients with Cyp2c19 AA Variant in SNP rs4244285Virginia Bosó, María José Herrero, Sergio Bea, María Galiana, Patricia Marrero, María Remedios Marqués, Julio Hernández, Jaime Sánchez-Plumed, José Luis Poveda and Salvador F. AliñoDrug Metabolism and Disposition February 2013, 41 (2) 480-487; DOI: https://doi.org/10.1124/dmd.112.047977
Savina, Paul M.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Sayama, Hiroyuki
- You have accessApplication of Hybrid Approach Based on Empirical and Physiological Concept for Predicting Pharmacokinetics in Humans—Usefulness of Exponent on Prospective Evaluation of PredictabilityHiroyuki Sayama, Hiroshi Komura and Motohiro KogayuDrug Metabolism and Disposition February 2013, 41 (2) 498-507; DOI: https://doi.org/10.1124/dmd.112.048819
Schiller, Hilmar
- You have accessThe Potential of Sutherlandia frutescens for Herb-Drug InteractionPius S. Fasinu, Heike Gutmann, Hilmar Schiller, Alexander-David James, Patrick J. Bouic and Bernd RosenkranzDrug Metabolism and Disposition February 2013, 41 (2) 488-497; DOI: https://doi.org/10.1124/dmd.112.049593
Sharma, Raman
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Sharma, Shringi
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Sharma, Sunita
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
Shen, Zhongzhou
- You have accessPrediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus HepatocytesJialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji YamazakiDrug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114
Shibasaki, Hiromi
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
Shuster, Diana L.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Sokal, Etienne
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Solon, Eric
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Stephenne, Xavier
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Strom, Stephen C.
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Sugiyama, Yuichi
- You have accessAnalysis of the Repaglinide Concentration Increase Produced by Gemfibrozil and Itraconazole Based on the Inhibition of the Hepatic Uptake Transporter and Metabolic EnzymesToshiyuki Kudo, Akihiro Hisaka, Yuichi Sugiyama and Kiyomi ItoDrug Metabolism and Disposition February 2013, 41 (2) 362-371; DOI: https://doi.org/10.1124/dmd.112.049460
Suzuki, Atsushi
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
T
Tahan, Veysel
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Tantisira, Kelan G.
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
Thakker, Dhiren R.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Thummel, Kenneth E.
- You have accessDrug Metabolism and Transport During Pregnancy: How Does Drug Disposition Change during Pregnancy and What Are the Mechanisms that Cause Such Changes?Nina Isoherranen and Kenneth E. ThummelDrug Metabolism and Disposition February 2013, 41 (2) 256-262; DOI: https://doi.org/10.1124/dmd.112.050245
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Tidwell, Richard R.
- You have accessCompartmental and Enzyme Kinetic Modeling To Elucidate the Biotransformation Pathway of a Centrally Acting Antitrypanosomal ProdrugClaudia N. Generaux, Garrett R. Ainslie, Arlene S. Bridges, Mohamed A. Ismail, David W. Boykin, Richard R. Tidwell, Dhiren R. Thakker and Mary F. PaineDrug Metabolism and Disposition February 2013, 41 (2) 518-528; DOI: https://doi.org/10.1124/dmd.112.048231
Topletz, Ariel R.
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Tracey, Helen
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Tsai, Jesse M.
- You have accessGestational Age-Dependent Changes in Gene Expression of Metabolic Enzymes and Transporters in Pregnant MiceDiana L. Shuster, Theo K. Bammler, Richard P. Beyer, James W. MacDonald, Jesse M. Tsai, Frederico M. Farin, Mary F. Hebert, Kenneth E. Thummel and Qingcheng MaoDrug Metabolism and Disposition February 2013, 41 (2) 332-342; DOI: https://doi.org/10.1124/dmd.112.049718
Tugnait, Meera
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
U
Unadkat, Jashvant D.
- You have accessInduction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell LinesIoannis Papageorgiou, Susan Grepper and Jashvant D. UnadkatDrug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015
V
VanAusdall, Jennifer L.
- You have accessCompartmentalization and Antiviral Effect of Efavirenz Metabolites in Blood Plasma, Seminal Plasma, and Cerebrospinal FluidLindsay B. Avery, Jennifer L. VanAusdall, Craig W. Hendrix and Namandjé N. BumpusDrug Metabolism and Disposition February 2013, 41 (2) 422-429; DOI: https://doi.org/10.1124/dmd.112.049601
Van Bocxlaer, Jan
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Van Winckel, Myriam
- You have accessIn Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease ScoresLies De Bock, Koen Boussery, Myriam Van Winckel, Peter De Paepe, Xavier Rogiers, Xavier Stephenne, Etienne Sokal and Jan Van BocxlaerDrug Metabolism and Disposition February 2013, 41 (2) 390-397; DOI: https://doi.org/10.1124/dmd.112.048504
Vaz, Alfin D.
- You have accessPharmacokinetics, Metabolism, and Excretion of the Antidiabetic Agent Ertugliflozin (PF-04971729) in Healthy Male SubjectsZhuang Miao, Gianluca Nucci, Neeta Amin, Raman Sharma, Vincent Mascitti, Meera Tugnait, Alfin D. Vaz, Ernesto Callegari and Amit S. KalgutkarDrug Metabolism and Disposition February 2013, 41 (2) 445-456; DOI: https://doi.org/10.1124/dmd.112.049551
Venkataramanan, Raman
- You have accessHepatobiliary Disposition of 17-OHPC and Taurocholate in Fetal Human Hepatocytes: A Comparison with Adult Human HepatocytesShringi Sharma, Ewa C. S. Ellis, Roberto Gramignoli, Kenneth Dorko, Veysel Tahan, Marc Hansel, Donald R. Mattison, Steve N. Caritis, Ronald N. Hines, Raman Venkataramanan and Stephen C. StromDrug Metabolism and Disposition February 2013, 41 (2) 296-304; DOI: https://doi.org/10.1124/dmd.112.044891
Villanueva, Silvina
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Vooturi, Sunil K.
- You have accessRETRACTION: Immunohistochemical and Functional Characterization of Peptide, Organic Cation, Neutral and Basic Amino Acid, and Monocarboxylate Drug Transporters in Human Ocular TissuesRajendra S. Kadam, Sunil K. Vooturi and Uday B. KompellaDrug Metabolism and Disposition February 2013, 41 (2) 466-474; DOI: https://doi.org/10.1124/dmd.112.045674
Vore, Mary
- You have accessInduction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen ReceptorMaría L. Ruiz, Juan P. Rigalli, Agostina Arias, Silvina Villanueva, Claudia Banchio, Mary Vore, Aldo D. Mottino and Viviana A. CataniaDrug Metabolism and Disposition February 2013, 41 (2) 275-280; DOI: https://doi.org/10.1124/dmd.112.047357
Vyhlidal, Carrie A.
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
W
Wang, Joanne
- You have accessHepatic Cyp2d and Cyp26a1 mRNAs and Activities Are Increased During Mouse PregnancyAriel R. Topletz, Huong N. Le, Nora Lee, John D. Chapman, Edward J. Kelly, Joanne Wang and Nina IsoherranenDrug Metabolism and Disposition February 2013, 41 (2) 312-319; DOI: https://doi.org/10.1124/dmd.112.049379
Ward, Robert M.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
Ware, Joseph A
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Webster, Lindsey O.
- You have accessIn Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase InhibitorMelinda J. Reese, Paul M. Savina, Grant T. Generaux, Helen Tracey, Joan E. Humphreys, Eri Kanaoka, Lindsey O. Webster, Kelly A. Harmon, James D. Clarke and Joseph W. PolliDrug Metabolism and Disposition February 2013, 41 (2) 353-361; DOI: https://doi.org/10.1124/dmd.112.048918
Weiss, Scott T.
- You have accessCotinine in Human Placenta Predicts Induction of Gene Expression in Fetal TissuesCarrie A. Vyhlidal, Amanda K. Riffel, Kathleen J. Haley, Sunita Sharma, Hongying Dai, Kelan G. Tantisira, Scott T. Weiss and J. Steven LeederDrug Metabolism and Disposition February 2013, 41 (2) 305-311; DOI: https://doi.org/10.1124/dmd.112.049999
Wong, Harvey
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
X
Xie, Cen
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
Y
Yacovino, Lindsay L.
- You have accessDown-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant MiceLindsay L. Yacovino, Christopher J. Gibson and Lauren M. AleksunesDrug Metabolism and Disposition February 2013, 41 (2) 320-325; DOI: https://doi.org/10.1124/dmd.112.047092
Yamazaki, Shinji
- You have accessPrediction of Crizotinib-Midazolam Interaction Using the Simcyp Population-Based Simulator: Comparison of CYP3A Time-Dependent Inhibition between Human Liver Microsomes versus HepatocytesJialin Mao, Theodore R. Johnson, Zhongzhou Shen and Shinji YamazakiDrug Metabolism and Disposition February 2013, 41 (2) 343-352; DOI: https://doi.org/10.1124/dmd.112.049114
Yokokawa, Akitomo
- You have accessIntraindividual and Interindividual Variabilities in Endogenous Cortisol 6β-Hydroxylation Clearance as an Index for In Vivo CYP3A Phenotyping in HumansHiromi Shibasaki, Kaori Hosoda, Mari Goto, Atsushi Suzuki, Akitomo Yokokawa, Kazuo Ishii and Takashi FurutaDrug Metabolism and Disposition February 2013, 41 (2) 475-479; DOI: https://doi.org/10.1124/dmd.112.048561
Yost, Garold S.
- You have accessMetabolic Pathways of Inhaled Glucocorticoids by the CYP3A EnzymesChad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward and Garold S. YostDrug Metabolism and Disposition February 2013, 41 (2) 379-389; DOI: https://doi.org/10.1124/dmd.112.046318
Yue, Qin
- You have accessEvaluation of Metabolism and Disposition of GDC-0152 in Rats Using 14C Labeling Strategy at Two Different Positions: A Novel Formation of Hippuric Acid from 4-Phenyl-5-Amino-1,2,3-ThiadiazoleQin Yue, Teresa Mulder, Patrick J. Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E.C.A. Hop, Harvey Wong and S. Cyrus KhojastehDrug Metabolism and Disposition February 2013, 41 (2) 508-517; DOI: https://doi.org/10.1124/dmd.112.047019
Z
Zhang, Peng
- You have accessDietary Regulation of Mouse Intestinal P450 Expression and Drug MetabolismPeng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu ZhangDrug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
Zhang, Qing-Yu
- You have accessDietary Regulation of Mouse Intestinal P450 Expression and Drug MetabolismPeng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu ZhangDrug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
Zhang, Yifan
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
Zhong, Dafang
- You have accessMetabolism and Pharmacokinetics of 3-n-Butylphthalide (NBP) in Humans: The Role of Cytochrome P450s and Alcohol Dehydrogenase in BiotransformationXingxing Diao, Pan Deng, Cen Xie, Xiuli Li, Dafang Zhong, Yifan Zhang and Xiaoyan ChenDrug Metabolism and Disposition February 2013, 41 (2) 430-444; DOI: https://doi.org/10.1124/dmd.112.049684
Zhou, Xin
- You have accessDietary Regulation of Mouse Intestinal P450 Expression and Drug MetabolismPeng Zhang, Kunzhi Jia, Cheng Fang, Xin Zhou, Xinxin Ding and Qing-Yu ZhangDrug Metabolism and Disposition February 2013, 41 (2) 529-535; DOI: https://doi.org/10.1124/dmd.112.049403
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