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Rapid CommunicationSpecial Section on Drug Metabolizing Enzymes and Transporters in Pregnancy

Quantitative Prediction of CYP2B6 Induction by Estradiol During Pregnancy: Potential Explanation for Increased Methadone Clearance During Pregnancy

Leslie J Dickmann and Nina Isoherranen
Drug Metabolism and Disposition February 2013, 41 (2) 270-274; DOI: https://doi.org/10.1124/dmd.112.047118

Article Information

vol. 41 no. 2 270-274
DOI 
https://doi.org/10.1124/dmd.112.047118
PubMed 
22815312
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 6, 2012
  • Accepted July 19, 2012
  • Published online January 17, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Leslie J Dickmann and
  2. Nina Isoherranen
  1. Department of Pharmacokinetics and Drug Metabolism, Amgen (L.J.D.), and Department of Pharmaceutics, School of Pharmacy, University of Washington (N.I.), Seattle, Washington
  1. Address Correspondence to:
    Dr. Nina Isoherranen, Department of Pharmaceutics, School of Pharmacy, University of Washington, Box 357610, H272 Health Science Building, Seattle, WA 98195-7610. E-mail: ni2{at}u.washington.edu
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Rapid CommunicationSpecial Section on Drug Metabolizing Enzymes and Transporters in Pregnancy

Estradiol Induces CYP2B6

Leslie J Dickmann and Nina Isoherranen
Drug Metabolism and Disposition February 1, 2013, 41 (2) 270-274; DOI: https://doi.org/10.1124/dmd.112.047118
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