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Research ArticleSpecial Section on Drug Metabolizing Enzymes and Transporters in Pregnancy

Induction of Hepatic CYP3A Enzymes by Pregnancy-Related Hormones: Studies in Human Hepatocytes and Hepatic Cell Lines

Ioannis Papageorgiou, Susan Grepper and Jashvant D. Unadkat
Drug Metabolism and Disposition February 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015

Article Information

vol. 41 no. 2 281-290
DOI 
https://doi.org/10.1124/dmd.112.049015
PubMed 
23223499
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 10, 2012
  • Accepted December 6, 2012
  • Published online January 17, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ioannis Papageorgiou,
  2. Susan Grepper, and
  3. Jashvant D. Unadkat
  1. Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington (I.P., J.D.U.), and LifeTechnologies, Carlsbad, California (S.G.)
  1. Address correspondence to:
    Jashvant D. Unadkat, Department of Pharmaceutics, School of Pharmacy, Box 357610, University of Washington, Seattle, WA 98195-7610. E-mail: jash{at}u.washington.edu
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Research ArticleSpecial Section on Drug Metabolizing Enzymes and Transporters in Pregnancy

Effect of Pregnancy-Related Hormones on Hepatic CYP3A Induction

Ioannis Papageorgiou, Susan Grepper and Jashvant D. Unadkat
Drug Metabolism and Disposition February 1, 2013, 41 (2) 281-290; DOI: https://doi.org/10.1124/dmd.112.049015
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