A Perspective on the Contribution of Metabolites to Drug-Drug Interaction Potential: The Need to Consider Both Circulating Levels and Inhibition Potency

Hongbin Yu; Donald Tweedie

doi:10.1124/dmd.112.048892

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A Perspective on the Contribution of Metabolites to Drug-Drug Interaction Potential: The Need to Consider Both Circulating Levels and Inhibition Potency

Hongbin Yu and Donald Tweedie

Drug Metabolism and Disposition March 2013, 41 (3) 536-540; DOI: https://doi.org/10.1124/dmd.112.048892

Hongbin Yu

Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut

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Donald Tweedie

Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, Connecticut

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Drug Metabolism and Disposition

Vol. 41, Issue 3

1 Mar 2013

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