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Research ArticleArticles

Involvement of UDP-Glucuronosyltransferases UGT1A9 and UGT2B7 in Ethanol Glucuronidation, and Interactions with Common Drugs of Abuse

Alaa Al Saabi, Delphine Allorge, François-Ludovic Sauvage, Gilles Tournel, Jean-michel Gaulier, Pierre Marquet and Nicolas Picard
Drug Metabolism and Disposition March 2013, 41 (3) 568-574; DOI: https://doi.org/10.1124/dmd.112.047878
Alaa Al Saabi
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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Delphine Allorge
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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François-Ludovic Sauvage
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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Gilles Tournel
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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Jean-michel Gaulier
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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Pierre Marquet
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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Nicolas Picard
EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
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Article Information

vol. 41 no. 3 568-574
DOI 
https://doi.org/10.1124/dmd.112.047878
PubMed 
23230132

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 12, 2012
  • Accepted December 10, 2012
  • Published online February 15, 2013.

Article Versions

  • Earlier version (December 10, 2012 - 10:04).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Alaa Al Saabi,
  2. Delphine Allorge,
  3. François-Ludovic Sauvage,
  4. Gilles Tournel,
  5. Jean-michel Gaulier,
  6. Pierre Marquet, and
  7. Nicolas Picard
  1. EA4483, Faculty of Medicine, Université Lille-Nord de France, Lille, France (A.A.S., D.A., G.T.); Centre Hospitalier Régional Universitaire de Lille, Laboratory of Toxicology, Lille, France (A.A.S., D.A.); INSERM, Unité Mixte de Recherche S-850, Limoges, France (A.A.S., F.-L.S., P.M., N.P.); and CHU Limoges, Department of Pharmacology and Toxicology, Limoges, France (F.-L.S., J.-m.G., P.M., N.P.)
  1. Address correspondence to:
    Dr. Nicolas Picard, Centre Hospitalier Universitaire de Limoges, Service de Pharmacologie-Toxicologie, 2 Avenue Martin-Luther King, 87042 Limoges cedex, France. E-mail: nicolas.picard{at}unilim.fr
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Drug Metabolism and Disposition: 41 (3)
Drug Metabolism and Disposition
Vol. 41, Issue 3
1 Mar 2013
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Research ArticleArticles

Ethanol Glucuronidation: Enzymes and Potential Interactions

Alaa Al Saabi, Delphine Allorge, François-Ludovic Sauvage, Gilles Tournel, Jean-michel Gaulier, Pierre Marquet and Nicolas Picard
Drug Metabolism and Disposition March 1, 2013, 41 (3) 568-574; DOI: https://doi.org/10.1124/dmd.112.047878

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Research ArticleArticles

Ethanol Glucuronidation: Enzymes and Potential Interactions

Alaa Al Saabi, Delphine Allorge, François-Ludovic Sauvage, Gilles Tournel, Jean-michel Gaulier, Pierre Marquet and Nicolas Picard
Drug Metabolism and Disposition March 1, 2013, 41 (3) 568-574; DOI: https://doi.org/10.1124/dmd.112.047878
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