Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

Brain Efflux Index To Investigate the Influence of Active Efflux on Brain Distribution of Pemetrexed and Methotrexate

Li Li, Sagar Agarwal and William F. Elmquist
Drug Metabolism and Disposition March 2013, 41 (3) 659-667; DOI: https://doi.org/10.1124/dmd.112.049254
Li Li
Department of Pharmaceutics, Brain Barriers Research Center, University of Minnesota, Minneapolis, Minnesota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sagar Agarwal
Department of Pharmaceutics, Brain Barriers Research Center, University of Minnesota, Minneapolis, Minnesota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
William F. Elmquist
Department of Pharmaceutics, Brain Barriers Research Center, University of Minnesota, Minneapolis, Minnesota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 41 no. 3 659-667
DOI 
https://doi.org/10.1124/dmd.112.049254
PubMed 
23297298

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 26, 2012
  • Accepted January 4, 2013
  • Published online February 15, 2013.

Article Versions

  • Earlier version (January 7, 2013 - 07:55).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Li Li,
  2. Sagar Agarwal, and
  3. William F. Elmquist
  1. Department of Pharmaceutics, Brain Barriers Research Center, University of Minnesota, Minneapolis, Minnesota
  1. Address correspondence to:
    William F. Elmquist, Department of Pharmaceutics, University of Minnesota, 9-177 Weaver Densford Hall, 308 Harvard Street SE, Minneapolis, MN 55455. E-mail: elmqu011{at}umn.edu
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 2013 to May 2022

AbstractFullPdf
Jan 201337606163
Feb 20134952068
Mar 20133341940
Apr 20131661733
May 20131001321
Jun 201361917
Jul 2013581821
Aug 2013371413
Sep 201369715
Oct 201374620
Nov 201337710
Dec 20131947
Jan 2014271310
Feb 20142576
Mar 2014533535
Apr 2014381715
May 2014412617
Jun 201434910
Jul 20142969
Aug 201414122
Sep 2014181212
Oct 20143495
Nov 201429148
Dec 20141764
Jan 201512710
Feb 20151787
Mar 201523157
Apr 201518124
May 201519115
Jun 201519194
Jul 2015121714
Aug 2015995
Sep 201528112
Oct 20151448
Nov 20151345
Dec 201531178
Jan 20161557
Feb 20161158
Mar 201612516
Apr 2016855
May 2016141110
Jun 201614610
Jul 20161684
Aug 201620112
Sep 20161053
Oct 20164246
Nov 2016121716
Dec 20164237
Jan 20172234
Feb 20170152
Mar 20171229
Apr 20172139
May 20171147
Jun 2017083
Jul 20172177
Aug 20170189
Sep 2017115712
Oct 201719213
Nov 20172219
Dec 201704616
Jan 201833435
Feb 201872454
Mar 2018118211
Apr 20180803
May 20181605
Jun 20180552
Jul 20180283
Aug 20180206
Sep 20180216
Oct 201804913
Nov 20182604
Dec 201848133
Jan 20196400
Feb 20196902
Mar 20193103
Apr 20192216
May 20191416
Jun 2019406
Jul 2019701
Aug 20191011
Sep 20191512
Oct 20191223
Nov 20191900
Dec 20192133
Jan 20201725
Feb 20201521
Mar 20201103
Apr 20201539
May 2020160201
Jun 2020918
Jul 2020810
Aug 2020109
Sep 2020325
Oct 20201103
Nov 20201712
Dec 20201213
Jan 202119105
Feb 2021271010
Mar 20211984
Apr 20211052
May 20213322
Jun 20212612
Jul 20214133
Aug 20211941
Sep 20211410
Oct 20211011
Nov 20214033
Dec 20211822
Jan 2022810
Feb 20221132
Mar 20222382
Apr 20221442
May 2022610

PreviousNext
Back to top

In this issue

Drug Metabolism and Disposition: 41 (3)
Drug Metabolism and Disposition
Vol. 41, Issue 3
1 Mar 2013
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Brain Efflux Index To Investigate the Influence of Active Efflux on Brain Distribution of Pemetrexed and Methotrexate
(Your Name) has forwarded a page to you from Drug Metabolism & Disposition
(Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Active Efflux of Pemetrexed and Methotrexate from Brain

Li Li, Sagar Agarwal and William F. Elmquist
Drug Metabolism and Disposition March 1, 2013, 41 (3) 659-667; DOI: https://doi.org/10.1124/dmd.112.049254

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Active Efflux of Pemetrexed and Methotrexate from Brain

Li Li, Sagar Agarwal and William F. Elmquist
Drug Metabolism and Disposition March 1, 2013, 41 (3) 659-667; DOI: https://doi.org/10.1124/dmd.112.049254
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Role of Human MSRA on Sulindac Activation
  • Determination of Acyl-, O-, and N-Glucuronide
  • Uptake as the RDS in Pevonedistat Hepatic Clearance
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2022 by the American Society for Pharmacology and Experimental Therapeutics