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Index by author

May 01, 2013; Volume 41,Issue 5

A

  1. An, Guohua

    1. Effect of Ketoconazole on the Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 and Its Two Active Metabolites in Healthy Volunteers: Population Analysis of Data from a Drug-Drug Interaction Study
      Guohua An, Wei Liu, David A. Katz, Gerard Marek, Walid Awni and Sandeep Dutta
      Drug Metabolism and Disposition May 2013, 41 (5) 1035-1045; DOI: https://doi.org/10.1124/dmd.112.049742

  2. Awni, Walid

    1. Effect of Ketoconazole on the Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 and Its Two Active Metabolites in Healthy Volunteers: Population Analysis of Data from a Drug-Drug Interaction Study
      Guohua An, Wei Liu, David A. Katz, Gerard Marek, Walid Awni and Sandeep Dutta
      Drug Metabolism and Disposition May 2013, 41 (5) 1035-1045; DOI: https://doi.org/10.1124/dmd.112.049742

B

  1. Barbara, Joanna E.

    1. Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate
      Joanna E. Barbara, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition May 2013, 41 (5) 1012-1022; DOI: https://doi.org/10.1124/dmd.113.051151

  2. Bi, Yi-An

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  3. Bowers, Gary D.

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  4. Brouwer, Kim L. R.

    1. Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides
      Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2013, 41 (5) 958-965; DOI: https://doi.org/10.1124/dmd.112.048272

  5. Buckley, David B.

    1. Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate
      Joanna E. Barbara, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition May 2013, 41 (5) 1012-1022; DOI: https://doi.org/10.1124/dmd.113.051151
    2. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  6. Bueters, Tjerk

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

C

  1. Chen, Jianjun

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  2. Chen, Zhongjian

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801

  3. Cheng, Qiuqiong

    1. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  4. Cherrington, Nathan J.

    1. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  5. Chism, John P.

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  6. Conde, J. J.

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  7. Cunningham, Elizabeth

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

D

  1. Dalvie, Deepak

    1. Which Metabolites Circulate?
      Cho-Ming Loi, Dennis A. Smith and Deepak Dalvie
      Drug Metabolism and Disposition May 2013, 41 (5) 933-951; DOI: https://doi.org/10.1124/dmd.112.050278

  2. Dienel, Angelika

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  3. Dingemanse, Jasper

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  4. Donepudi, Ajay C.

    1. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  5. Doroshyenko, Oxana

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  6. Drolet, Benoit

    1. Decreased CYP3A Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome: Is Fatty Liver Infiltration Involved?
      Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet and Chantale Simard
      Drug Metabolism and Disposition May 2013, 41 (5) 952-957; DOI: https://doi.org/10.1124/dmd.112.050641

  7. Duffel, Michael W.

    1. Modification of the Catalytic Function of Human Hydroxysteroid Sulfotransferase hSULT2A1 by Formation of Disulfide Bonds
      Xiaoyan Qin, Lynn M. Teesch and Michael W. Duffel
      Drug Metabolism and Disposition May 2013, 41 (5) 1094-1103; DOI: https://doi.org/10.1124/dmd.112.050534

  8. Dumont, Etienne

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  9. Dutta, Sandeep

    1. Effect of Ketoconazole on the Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 and Its Two Active Metabolites in Healthy Volunteers: Population Analysis of Data from a Drug-Drug Interaction Study
      Guohua An, Wei Liu, David A. Katz, Gerard Marek, Walid Awni and Sandeep Dutta
      Drug Metabolism and Disposition May 2013, 41 (5) 1035-1045; DOI: https://doi.org/10.1124/dmd.112.049742

E

  1. Eddington, Natalie D.

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

  2. Eklund, Göran

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

  3. El-Kattan, Ayman F.

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  4. Elmore, Charles S.

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

  5. Endo, Seiko

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

F

  1. Fahmi, Odette A.

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  2. Fischer, Thomas

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

  3. Fuhr, Uwe

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

G

  1. Goosen, Theunis C.

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  2. Gramatté, Thomas

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  3. Gu, Liqiang

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801

  4. Guo, Jian

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

H

  1. Hassan, Hazem E.

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

  2. Hawke, Roy L.

    1. Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides
      Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2013, 41 (5) 958-965; DOI: https://doi.org/10.1124/dmd.112.048272

  3. Hoch, Matthias

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  4. Hoever, Petra

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  5. Holenz, Jörg

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

  6. Honda, Tomohiro

    1. Tissue Distribution and Identification of Radioactivity Components at Elimination Phase after Oral Administration of [14C]CS-1036, an α-Amylase Inhibitor, to Rats
      Tomohiro Honda, Hideo Takakusa, Takahiro Murai and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1125-1133; DOI: https://doi.org/10.1124/dmd.112.050617

  7. Hopfgartner, Gérard

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  8. Hu, Jun

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

  9. Huo, Xiaokui

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  10. Huynh, Phuong

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

I

  1. Ishizuka, Tomoko

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

  2. Izumi, Takashi

    1. Tissue Distribution and Identification of Radioactivity Components at Elimination Phase after Oral Administration of [14C]CS-1036, an α-Amylase Inhibitor, to Rats
      Tomohiro Honda, Hideo Takakusa, Takahiro Murai and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1125-1133; DOI: https://doi.org/10.1124/dmd.112.050617
    2. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

J

  1. Janjetovic, Zorica

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  2. Jiang, Huidi

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801

  3. Jiang, Xi-Ling

    1. Pharmacokinetic Interactions between Monoamine Oxidase A Inhibitor Harmaline and 5-Methoxy-N,N-Dimethyltryptamine, and the Impact of CYP2D6 Status
      Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager and Ai-Ming Yu
      Drug Metabolism and Disposition May 2013, 41 (5) 975-986; DOI: https://doi.org/10.1124/dmd.112.050724

K

  1. Karlström, Sofia

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

  2. Kato, Ayako

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

  3. Katz, David A.

    1. Effect of Ketoconazole on the Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 and Its Two Active Metabolites in Healthy Volunteers: Population Analysis of Data from a Drug-Drug Interaction Study
      Guohua An, Wei Liu, David A. Katz, Gerard Marek, Walid Awni and Sandeep Dutta
      Drug Metabolism and Disposition May 2013, 41 (5) 1035-1045; DOI: https://doi.org/10.1124/dmd.112.049742

  4. Kazmi, Faraz

    1. Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate
      Joanna E. Barbara, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition May 2013, 41 (5) 1012-1022; DOI: https://doi.org/10.1124/dmd.113.051151

  5. Klement, Stephan

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  6. Köck, Kathleen

    1. Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides
      Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2013, 41 (5) 958-965; DOI: https://doi.org/10.1124/dmd.112.048272

  7. Kurihara, Atsushi

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

  8. Kurtinecz, Milena

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  9. Kusano, Kazutomi

    1. Species Difference in the Mechanism of Nonlinear Pharmacokinetics of E2074, a Novel Sodium Channel Inhibitor, in Rats, Dogs, and Monkeys
      Yoko Nagaya, Osamu Takenaka, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition May 2013, 41 (5) 1004-1011; DOI: https://doi.org/10.1124/dmd.112.050062

L

  1. Lai, Yurong

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  2. Lam, Justine L.

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  3. Lee, Insong J.

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

  4. Levac, Xavier

    1. Decreased CYP3A Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome: Is Fatty Liver Infiltration Involved?
      Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet and Chantale Simard
      Drug Metabolism and Disposition May 2013, 41 (5) 952-957; DOI: https://doi.org/10.1124/dmd.112.050641

  5. Li, Wei

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  6. Lin, Jian

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  7. Lindgren, Anders

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

  8. Liu, Kexin

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  9. Liu, Qi

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  10. Liu, Wei

    1. Effect of Ketoconazole on the Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 and Its Two Active Metabolites in Healthy Volunteers: Population Analysis of Data from a Drug-Drug Interaction Study
      Guohua An, Wei Liu, David A. Katz, Gerard Marek, Walid Awni and Sandeep Dutta
      Drug Metabolism and Disposition May 2013, 41 (5) 1035-1045; DOI: https://doi.org/10.1124/dmd.112.049742

  11. Loi, Cho-Ming

    1. Which Metabolites Circulate?
      Cho-Ming Loi, Dennis A. Smith and Deepak Dalvie
      Drug Metabolism and Disposition May 2013, 41 (5) 933-951; DOI: https://doi.org/10.1124/dmd.112.050278

  12. Lu, Zhenqiang James

    1. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  13. Lück, Hendrik

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

M

  1. Ma, Xiaochi

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  2. Mager, Donald E.

    1. Pharmacokinetic Interactions between Monoamine Oxidase A Inhibitor Harmaline and 5-Methoxy-N,N-Dimethyltryptamine, and the Impact of CYP2D6 Status
      Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager and Ai-Ming Yu
      Drug Metabolism and Disposition May 2013, 41 (5) 975-986; DOI: https://doi.org/10.1124/dmd.112.050724

  3. Malmquist, Jonas

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

  4. Marek, Gerard

    1. Effect of Ketoconazole on the Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 and Its Two Active Metabolites in Healthy Volunteers: Population Analysis of Data from a Drug-Drug Interaction Study
      Guohua An, Wei Liu, David A. Katz, Gerard Marek, Walid Awni and Sandeep Dutta
      Drug Metabolism and Disposition May 2013, 41 (5) 1035-1045; DOI: https://doi.org/10.1124/dmd.112.049742

  5. Mason, Clifford W.

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

  6. Meng, Qiang

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  7. Miraval, Tommaso

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  8. More, Vijay R.

    1. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  9. Murai, Takahiro

    1. Tissue Distribution and Identification of Radioactivity Components at Elimination Phase after Oral Administration of [14C]CS-1036, an α-Amylase Inhibitor, to Rats
      Tomohiro Honda, Hideo Takakusa, Takahiro Murai and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1125-1133; DOI: https://doi.org/10.1124/dmd.112.050617

  10. Myers, Alan L.

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

N

  1. Nagar, Swati

    1. Pulmonary Metabolism of Resveratrol: In Vitro and In Vivo Evidence
      Satish Sharan and Swati Nagar
      Drug Metabolism and Disposition May 2013, 41 (5) 1163-1169; DOI: https://doi.org/10.1124/dmd.113.051326

  2. Nagaya, Yoko

    1. Species Difference in the Mechanism of Nonlinear Pharmacokinetics of E2074, a Novel Sodium Channel Inhibitor, in Rats, Dogs, and Monkeys
      Yoko Nagaya, Osamu Takenaka, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition May 2013, 41 (5) 1004-1011; DOI: https://doi.org/10.1124/dmd.112.050062

  3. Nakagawa, Tetsuya

    1. Significance of Reductive Metabolism in Human Intestine and Quantitative Prediction of Intestinal First-Pass Metabolism by Cytosolic Reductive Enzymes
      Haruka Nishimuta, Tetsuya Nakagawa, Naruaki Nomura and Masashi Yabuki
      Drug Metabolism and Disposition May 2013, 41 (5) 1104-1111; DOI: https://doi.org/10.1124/dmd.113.051177

  4. Nishimuta, Haruka

    1. Significance of Reductive Metabolism in Human Intestine and Quantitative Prediction of Intestinal First-Pass Metabolism by Cytosolic Reductive Enzymes
      Haruka Nishimuta, Tetsuya Nakagawa, Naruaki Nomura and Masashi Yabuki
      Drug Metabolism and Disposition May 2013, 41 (5) 1104-1111; DOI: https://doi.org/10.1124/dmd.113.051177

  5. Nomura, Naruaki

    1. Significance of Reductive Metabolism in Human Intestine and Quantitative Prediction of Intestinal First-Pass Metabolism by Cytosolic Reductive Enzymes
      Haruka Nishimuta, Tetsuya Nakagawa, Naruaki Nomura and Masashi Yabuki
      Drug Metabolism and Disposition May 2013, 41 (5) 1104-1111; DOI: https://doi.org/10.1124/dmd.113.051177

O

  1. O’Mara, Kathryn

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  2. Oberlies, Nicholas H.

    1. Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides
      Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2013, 41 (5) 958-965; DOI: https://doi.org/10.1124/dmd.112.048272

P

  1. Pan, Hao

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801

  2. Parkinson, Andrew

    1. Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate
      Joanna E. Barbara, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition May 2013, 41 (5) 1012-1022; DOI: https://doi.org/10.1124/dmd.113.051151

  3. Patel, Parul

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  4. Patoine, Dany

    1. Decreased CYP3A Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome: Is Fatty Liver Infiltration Involved?
      Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet and Chantale Simard
      Drug Metabolism and Disposition May 2013, 41 (5) 952-957; DOI: https://doi.org/10.1124/dmd.112.050641

  5. Peng, Jinyong

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  6. Pilote, Sylvie

    1. Decreased CYP3A Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome: Is Fatty Liver Infiltration Involved?
      Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet and Chantale Simard
      Drug Metabolism and Disposition May 2013, 41 (5) 952-957; DOI: https://doi.org/10.1124/dmd.112.050641

  7. Powell, Mark E.

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

Q

  1. Qin, Xiaoyan

    1. Modification of the Catalytic Function of Human Hydroxysteroid Sulfotransferase hSULT2A1 by Formation of Disulfide Bonds
      Xiaoyan Qin, Lynn M. Teesch and Michael W. Duffel
      Drug Metabolism and Disposition May 2013, 41 (5) 1094-1103; DOI: https://doi.org/10.1124/dmd.112.050534

R

  1. Reese, Melinda J.

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  2. Resuello, Christina M.

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

  3. Rokitta, Dennis

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  4. Rotter, Charles J.

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  5. Rozehnal, Veronika

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

S

  1. Schläfke, Sandra

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  2. Shakeri-Nejad, Kasra

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  3. Sharan, Satish

    1. Pulmonary Metabolism of Resveratrol: In Vitro and In Vivo Evidence
      Satish Sharan and Swati Nagar
      Drug Metabolism and Disposition May 2013, 41 (5) 1163-1169; DOI: https://doi.org/10.1124/dmd.113.051326

  4. Shen, Hong-Wu

    1. Pharmacokinetic Interactions between Monoamine Oxidase A Inhibitor Harmaline and 5-Methoxy-N,N-Dimethyltryptamine, and the Impact of CYP2D6 Status
      Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager and Ai-Ming Yu
      Drug Metabolism and Disposition May 2013, 41 (5) 975-986; DOI: https://doi.org/10.1124/dmd.112.050724

  5. Sigafoos, James

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  6. Simard, Chantale

    1. Decreased CYP3A Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome: Is Fatty Liver Infiltration Involved?
      Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet and Chantale Simard
      Drug Metabolism and Disposition May 2013, 41 (5) 952-957; DOI: https://doi.org/10.1124/dmd.112.050641

  7. Sinz, Michael W.

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

  8. Slitt, Angela L.

    1. Alcohol Cirrhosis Alters Nuclear Receptor and Drug Transporter Expression in Human Liver
      Vijay R. More, Qiuqiong Cheng, Ajay C. Donepudi, David B. Buckley, Zhenqiang James Lu, Nathan J. Cherrington and Angela L. Slitt
      Drug Metabolism and Disposition May 2013, 41 (5) 1148-1155; DOI: https://doi.org/10.1124/dmd.112.049676

  9. Slominski, Andrzej T.

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  10. Smith, Dennis A.

    1. Which Metabolites Circulate?
      Cho-Ming Loi, Dennis A. Smith and Deepak Dalvie
      Drug Metabolism and Disposition May 2013, 41 (5) 933-951; DOI: https://doi.org/10.1124/dmd.112.050278

  11. Stump, Patrick

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  12. Sun, Huijun

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  13. Sun, Siyuan

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801

  14. Swahn, Britt-Marie

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

T

  1. Takakusa, Hideo

    1. Tissue Distribution and Identification of Radioactivity Components at Elimination Phase after Oral Administration of [14C]CS-1036, an α-Amylase Inhibitor, to Rats
      Tomohiro Honda, Hideo Takakusa, Takahiro Murai and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1125-1133; DOI: https://doi.org/10.1124/dmd.112.050617

  2. Takenaka, Osamu

    1. Species Difference in the Mechanism of Nonlinear Pharmacokinetics of E2074, a Novel Sodium Channel Inhibitor, in Rats, Dogs, and Monkeys
      Yoko Nagaya, Osamu Takenaka, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition May 2013, 41 (5) 1004-1011; DOI: https://doi.org/10.1124/dmd.112.050062

  3. Tang, Edith K. Y.

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  4. Teesch, Lynn M.

    1. Modification of the Catalytic Function of Human Hydroxysteroid Sulfotransferase hSULT2A1 by Formation of Disulfide Bonds
      Xiaoyan Qin, Lynn M. Teesch and Michael W. Duffel
      Drug Metabolism and Disposition May 2013, 41 (5) 1094-1103; DOI: https://doi.org/10.1124/dmd.112.050534

  5. Tenero, David

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  6. Tieu, Elaine W.

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  7. Tomayko, John F.

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  8. Treiber, Alexander

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  9. Tuckey, Robert C.

    1. Hydroxylation of CYP11A1-Derived Products of Vitamin D3 Metabolism by Human and Mouse CYP27B1
      Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey
      Drug Metabolism and Disposition May 2013, 41 (5) 1112-1124; DOI: https://doi.org/10.1124/dmd.113.050955

  10. Turek, Dominika

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

V

  1. Varma, Manthena V. S.

    1. Quantitative Prediction of Repaglinide-Rifampicin Complex Drug Interactions Using Dynamic and Static Mechanistic Models: Delineating Differential CYP3A4 Induction and OATP1B1 Inhibition Potential of Rifampicin
      Manthena V. S. Varma, Jian Lin, Yi-An Bi, Charles J. Rotter, Odette A. Fahmi, Justine L. Lam, Ayman F. El-Kattan, Theunis C. Goosen and Yurong Lai
      Drug Metabolism and Disposition May 2013, 41 (5) 966-974; DOI: https://doi.org/10.1124/dmd.112.050583

  2. Vishwanathan, Karthick

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

  3. von Berg, Stefan

    1. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring
      Anders Lindgren, Göran Eklund, Dominika Turek, Jonas Malmquist, Britt-Marie Swahn, Jörg Holenz, Stefan von Berg, Sofia Karlström and Tjerk Bueters
      Drug Metabolism and Disposition May 2013, 41 (5) 1134-1147; DOI: https://doi.org/10.1124/dmd.112.050351

W

  1. Wagner-Redeker, Winfried

    1. Elucidation of the Metabolic Pathways and the Resulting Multiple Metabolites of Almorexant, a Dual Orexin Receptor Antagonist, in Humans
      Jasper Dingemanse, Petra Hoever, Matthias Hoch, Alexander Treiber, Winfried Wagner-Redeker, Tommaso Miraval, Gérard Hopfgartner and Kasra Shakeri-Nejad
      Drug Metabolism and Disposition May 2013, 41 (5) 1046-1059; DOI: https://doi.org/10.1124/dmd.112.050120

  2. Wang, Changyuan

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  3. Wang, Duan

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

  4. Wang, Hongbing

    1. Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
      Hazem E. Hassan, Alan L. Myers, Insong J. Lee, Clifford W. Mason, Duan Wang, Michael W. Sinz, Hongbing Wang and Natalie D. Eddington
      Drug Metabolism and Disposition May 2013, 41 (5) 1060-1069; DOI: https://doi.org/10.1124/dmd.112.050401

X

  1. Xie, Ying

    1. Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides
      Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2013, 41 (5) 958-965; DOI: https://doi.org/10.1124/dmd.112.048272

Y

  1. Yabuki, Masashi

    1. Significance of Reductive Metabolism in Human Intestine and Quantitative Prediction of Intestinal First-Pass Metabolism by Cytosolic Reductive Enzymes
      Haruka Nishimuta, Tetsuya Nakagawa, Naruaki Nomura and Masashi Yabuki
      Drug Metabolism and Disposition May 2013, 41 (5) 1104-1111; DOI: https://doi.org/10.1124/dmd.113.051177

  2. Yoshigae, Yasushi

    1. Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine
      Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara and Takashi Izumi
      Drug Metabolism and Disposition May 2013, 41 (5) 1156-1162; DOI: https://doi.org/10.1124/dmd.113.051482

  3. Yoshimura, Tsutomu

    1. Species Difference in the Mechanism of Nonlinear Pharmacokinetics of E2074, a Novel Sodium Channel Inhibitor, in Rats, Dogs, and Monkeys
      Yoko Nagaya, Osamu Takenaka, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition May 2013, 41 (5) 1004-1011; DOI: https://doi.org/10.1124/dmd.112.050062

  4. Young, Graeme C.

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

  5. Yu, Ai-Ming

    1. Pharmacokinetic Interactions between Monoamine Oxidase A Inhibitor Harmaline and 5-Methoxy-N,N-Dimethyltryptamine, and the Impact of CYP2D6 Status
      Xi-Ling Jiang, Hong-Wu Shen, Donald E. Mager and Ai-Ming Yu
      Drug Metabolism and Disposition May 2013, 41 (5) 975-986; DOI: https://doi.org/10.1124/dmd.112.050724

  6. Yueh, Yun Lan

    1. Disposition and Metabolism of GSK2251052 in Humans: A Novel Boron-Containing Antibiotic
      Gary D. Bowers, David Tenero, Parul Patel, Phuong Huynh, James Sigafoos, Kathryn O’Mara, Graeme C. Young, Etienne Dumont, Elizabeth Cunningham, Milena Kurtinecz, Patrick Stump, J. J. Conde, John P. Chism, Melinda J. Reese, Yun Lan Yueh and John F. Tomayko
      Drug Metabolism and Disposition May 2013, 41 (5) 1070-1081; DOI: https://doi.org/10.1124/dmd.112.050153

Z

  1. Zadoyan, Gregor

    1. Drug Cocktail Interaction Study on the Effect of the Orally Administered Lavender Oil Preparation Silexan on Cytochrome P450 Enzymes in Healthy Volunteers
      Oxana Doroshyenko, Dennis Rokitta, Gregor Zadoyan, Stephan Klement, Sandra Schläfke, Angelika Dienel, Thomas Gramatté, Hendrik Lück and Uwe Fuhr
      Drug Metabolism and Disposition May 2013, 41 (5) 987-993; DOI: https://doi.org/10.1124/dmd.112.050203

  2. Zeng, Su

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801

  3. Zhang, Aijie

    1. Involvement of Organic Anion-Transporting Polypeptides in the Hepatic Uptake of Dioscin in Rats and Humans
      Aijie Zhang, Changyuan Wang, Qi Liu, Qiang Meng, Jinyong Peng, Huijun Sun, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition May 2013, 41 (5) 994-1003; DOI: https://doi.org/10.1124/dmd.112.049452

  4. Zhang, Minli

    1. Contribution of Artifacts to N-Methylated Piperazine Cyanide Adduct Formation In Vitro from N-Alkyl Piperazine Analogs
      Minli Zhang, Christina M. Resuello, Jian Guo, Mark E. Powell, Charles S. Elmore, Jun Hu and Karthick Vishwanathan
      Drug Metabolism and Disposition May 2013, 41 (5) 1023-1034; DOI: https://doi.org/10.1124/dmd.112.050450

  5. Zhou, Hui

    1. Metabolism of Bis(4-fluorobenzyl)trisulfide and Its Formation of Hemoglobin Adduct in Rat Erythrocytes
      Hao Pan, Liqiang Gu, Siyuan Sun, Zhongjian Chen, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition May 2013, 41 (5) 1082-1093; DOI: https://doi.org/10.1124/dmd.112.048801
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