Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania

Department of Drug Metabolism and Pharmacokinetics (G.D.B., P.H., J.S., K.O., J.P.C., M.J.R., Y.L.Y.), and Infectious Diseases Therapeutic Area (P.P.), GlaxoSmithKline, Research Triangle Park, North Carolina; Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Ware, UK (G.C.Y.); Department of Clinical Pharmacology, Modeling and Simulation (D.T.), API Chemistry and Analysis (J.J.C.), and Projects, Clinical Platforms and Sciences (E.C., P.S.), GlaxoSmithKline, King of Prussia, Pennsylvania; and Clinical Statistics (M.K.) and Infectious Diseases Therapeutic Area (E.D., J.F.T.), GlaxoSmithKline, Collegeville, Pennsylvania