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The Effect of Breast Cancer Resistance Protein, Multidrug Resistant Protein 1, and Organic Anion-Transporting Polypeptide 1B3 on the Antitumor Efficacy of the Lipophilic Camptothecin 7-t-Butyldimethylsilyl-10-Hydroxycamptothecin (AR-67) In Vitro

Eleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos Leggas
Drug Metabolism and Disposition July 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021

Article Information

vol. 41 no. 7 1404-1413
DOI 
https://doi.org/10.1124/dmd.112.050021
PubMed 
23620484
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 12, 2012
  • Accepted April 24, 2013
  • Published online June 13, 2013.

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Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Eleftheria Tsakalozou,
  2. Eyob D. Adane,
  3. Kuei-Ling Kuo,
  4. Abigail Daily,
  5. Jeffrey A. Moscow, and
  6. Markos Leggas
  1. Department of Pharmaceutical Sciences, College of Pharmacy (E.T., E.D.A., K.-L.K., M.L.), and Department of Pediatrics, College of Medicine, University of Kentucky, Lexington, Kentucky (A.D., J.A.M.)
  1. Address correspondence to:
    Dr. Markos Leggas, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone Avenue, Room 323, Lexington, KY 40536. E-mail: mlegg2{at}email.uky.edu
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Impact of Transporters on the Cytotoxicity of AR-67 In Vitro

Eleftheria Tsakalozou, Eyob D. Adane, Kuei-Ling Kuo, Abigail Daily, Jeffrey A. Moscow and Markos Leggas
Drug Metabolism and Disposition July 1, 2013, 41 (7) 1404-1413; DOI: https://doi.org/10.1124/dmd.112.050021
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