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Drug Metabolism & Disposition

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Table of Contents

August 01, 2013; Volume 41,Issue 8

Articles

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    Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor
    Heather Eng, Raman Sharma, Thomas S. McDonald, David J. Edmonds, Jean-Philippe Fortin, Xianping Li, Benjamin D. Stevens, David A. Griffith, Chris Limberakis, Whitney M. Nolte, David A. Price, Margaret Jackson and Amit S. Kalgutkar
    Drug Metabolism and Disposition August 2013, 41 (8) 1470-1479; DOI: https://doi.org/10.1124/dmd.113.052183
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    Tissue Distribution, Ontogeny, and Chemical Induction of Aldo-Keto Reductases in Mice
    Matthew Pratt-Hyatt, Andrew J. Lickteig and Curtis D. Klaassen
    Drug Metabolism and Disposition August 2013, 41 (8) 1480-1487; DOI: https://doi.org/10.1124/dmd.113.051904
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    Comparison of Endogenous 4β-Hydroxycholesterol with Midazolam as Markers for CYP3A4 Induction by Rifampicin
    Linda Björkhem-Bergman, Tobias Bäckström, Hanna Nylén, Yuko Rönquist-Nii, Eva Bredberg, Tommy B. Andersson, Leif Bertilsson and Ulf Diczfalusy
    Drug Metabolism and Disposition August 2013, 41 (8) 1488-1493; DOI: https://doi.org/10.1124/dmd.113.052316
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    Milk Thistle’s Active Components Silybin and Isosilybin: Novel Inhibitors of PXR-Mediated CYP3A4 Induction
    Kim D. Mooiman, Roel F. Maas-Bakker, Ed E. Moret, Jos H. Beijnen, Jan H. M. Schellens and Irma Meijerman
    Drug Metabolism and Disposition August 2013, 41 (8) 1494-1504; DOI: https://doi.org/10.1124/dmd.113.050971
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    Regulation of Murine Hepatic Hydroxysteroid Sulfotransferase Expression in Hyposulfatemic Mice and in a Cell Model of 3′-Phosphoadenosine-5′-Phosphosulfate Deficiency
    Kathleen G. Barrett, Hailin Fang, Mary D. Gargano, Daniel Markovich, Thomas A. Kocarek and Melissa Runge-Morris
    Drug Metabolism and Disposition August 2013, 41 (8) 1505-1513; DOI: https://doi.org/10.1124/dmd.113.051912
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    In Vivo Assessment of the Impact of Efflux Transporter on Oral Drug Absorption Using Portal Vein–Cannulated Rats
    Yoshiki Matsuda, Yoshihiro Konno, Takashi Hashimoto, Mika Nagai, Takayuki Taguchi, Masahiro Satsukawa and Shinji Yamashita
    Drug Metabolism and Disposition August 2013, 41 (8) 1514-1521; DOI: https://doi.org/10.1124/dmd.113.051680
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    Hepatocellular Organic Anion–Transporting Polypeptides (OATPs) and Multidrug Resistance–Associated Protein 2 (MRP2) Are Inhibited by Silibinin
    Katrin Wlcek, Fabienne Koller, Peter Ferenci and Bruno Stieger
    Drug Metabolism and Disposition August 2013, 41 (8) 1522-1528; DOI: https://doi.org/10.1124/dmd.113.051037
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    Glucuronidation of a Sarpogrelate Active Metabolite Is Mediated by UDP-Glucuronosyltransferases 1A4, 1A9, and 2B4
    Hyo-Ji Kim, Eun Sook Jeong, Kyung-Ah Seo, Kye Jung Shin, Yeon Jae Choi, Su-Jun Lee, Jong Lyul Ghim, Dong-Ryul Sohn, Jae-Gook Shin and Dong-Hyun Kim
    Drug Metabolism and Disposition August 2013, 41 (8) 1529-1537; DOI: https://doi.org/10.1124/dmd.113.051862
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    Genetic Variation in Aldo-Keto Reductase 1D1 (AKR1D1) Affects the Expression and Activity of Multiple Cytochrome P450s
    Amarjit S. Chaudhry, Ranjit K. Thirumaran, Kazuto Yasuda, Xia Yang, Yiping Fan, Stephen C. Strom and Erin G. Schuetz
    Drug Metabolism and Disposition August 2013, 41 (8) 1538-1547; DOI: https://doi.org/10.1124/dmd.113.051672
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    Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing Drugs
    Youssef Daali, Philippe Millet, Pierre Dayer and Catherine M. Pastor
    Drug Metabolism and Disposition August 2013, 41 (8) 1548-1556; DOI: https://doi.org/10.1124/dmd.113.051870
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    Nanoparticle Formulation of a Poorly Soluble Cannabinoid Receptor 1 Antagonist Improves Absorption by Rat and Human Intestine
    Sanna Siissalo, Hans de Waard, Marina H. de Jager, Rose Hayeshi, Henderik W. Frijlink, Wouter L.J. Hinrichs, Heike Dinter-Heidorn, Annie van Dam, Johannes H. Proost, Geny M.M. Groothuis and Inge A.M. de Graaf
    Drug Metabolism and Disposition August 2013, 41 (8) 1557-1565; DOI: https://doi.org/10.1124/dmd.112.049585
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    Effect of CYP3A5 Expression on the Inhibition of CYP3A-Catalyzed Drug Metabolism: Impact on Modeling CYP3A-Mediated Drug-Drug Interactions
    Yoshiyuki Shirasaka, Shu-Ying Chang, Mary F. Grubb, Chi-Chi Peng, Kenneth E. Thummel, Nina Isoherranen and A. David Rodrigues
    Drug Metabolism and Disposition August 2013, 41 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.049940
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    In Vitro Characterization of Axitinib Interactions with Human Efflux and Hepatic Uptake Transporters: Implications for Disposition and Drug Interactions
    Eric L. Reyner, Samantha Sevidal, Mark A. West, Andrea Clouser-Roche, Sascha Freiwald, Katherine Fenner, Mohammed Ullah, Caroline A. Lee and Bill J. Smith
    Drug Metabolism and Disposition August 2013, 41 (8) 1575-1583; DOI: https://doi.org/10.1124/dmd.113.051193
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    Pharmacokinetic Study of the Structural Components of Adenosine Diphosphate-Encapsulated Liposomes Coated with Fibrinogen γ-Chain Dodecapeptide as a Synthetic Platelet Substitute
    Kazuaki Taguchi, Hayato Ujihira, Shigeru Ogaki, Hiroshi Watanabe, Atsushi Fujiyama, Mami Doi, Yosuke Okamura, Shinji Takeoka, Yasuo Ikeda, Makoto Handa, Masaki Otagiri and Toru Maruyama
    Drug Metabolism and Disposition August 2013, 41 (8) 1584-1591; DOI: https://doi.org/10.1124/dmd.112.050005
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    Effect of P-Glycoprotein and Breast Cancer Resistance Protein Inhibition on the Pharmacokinetics of Sunitinib in Rats
    Sachiko Kunimatsu, Tomoyuki Mizuno, Masahide Fukudo and Toshiya Katsura
    Drug Metabolism and Disposition August 2013, 41 (8) 1592-1597; DOI: https://doi.org/10.1124/dmd.112.050286
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Drug Metabolism and Disposition: 41 (8)
Drug Metabolism and Disposition
Vol. 41, Issue 8
1 Aug 2013
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