Table of Contents

Articles

• You have access

  Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor

  Heather Eng, Raman Sharma, Thomas S. McDonald, David J. Edmonds, Jean-Philippe Fortin, Xianping Li, Benjamin D. Stevens, David A. Griffith, Chris Limberakis, Whitney M. Nolte, David A. Price, Margaret Jackson and Amit S. Kalgutkar

  Drug Metabolism and Disposition August 2013, 41 (8) 1470-1479; DOI: https://doi.org/10.1124/dmd.113.052183
• You have access

  Tissue Distribution, Ontogeny, and Chemical Induction of Aldo-Keto Reductases in Mice

  Matthew Pratt-Hyatt, Andrew J. Lickteig and Curtis D. Klaassen

  Drug Metabolism and Disposition August 2013, 41 (8) 1480-1487; DOI: https://doi.org/10.1124/dmd.113.051904
• You have access

  Comparison of Endogenous 4β-Hydroxycholesterol with Midazolam as Markers for CYP3A4 Induction by Rifampicin

  Linda Björkhem-Bergman, Tobias Bäckström, Hanna Nylén, Yuko Rönquist-Nii, Eva Bredberg, Tommy B. Andersson, Leif Bertilsson and Ulf Diczfalusy

  Drug Metabolism and Disposition August 2013, 41 (8) 1488-1493; DOI: https://doi.org/10.1124/dmd.113.052316
• You have access

  Milk Thistle’s Active Components Silybin and Isosilybin: Novel Inhibitors of PXR-Mediated CYP3A4 Induction

  Kim D. Mooiman, Roel F. Maas-Bakker, Ed E. Moret, Jos H. Beijnen, Jan H. M. Schellens and Irma Meijerman

  Drug Metabolism and Disposition August 2013, 41 (8) 1494-1504; DOI: https://doi.org/10.1124/dmd.113.050971
• You have access

  Regulation of Murine Hepatic Hydroxysteroid Sulfotransferase Expression in Hyposulfatemic Mice and in a Cell Model of 3′-Phosphoadenosine-5′-Phosphosulfate Deficiency

  Kathleen G. Barrett, Hailin Fang, Mary D. Gargano, Daniel Markovich, Thomas A. Kocarek and Melissa Runge-Morris

  Drug Metabolism and Disposition August 2013, 41 (8) 1505-1513; DOI: https://doi.org/10.1124/dmd.113.051912
• You have access

  In Vivo Assessment of the Impact of Efflux Transporter on Oral Drug Absorption Using Portal Vein–Cannulated Rats

  Yoshiki Matsuda, Yoshihiro Konno, Takashi Hashimoto, Mika Nagai, Takayuki Taguchi, Masahiro Satsukawa and Shinji Yamashita

  Drug Metabolism and Disposition August 2013, 41 (8) 1514-1521; DOI: https://doi.org/10.1124/dmd.113.051680
• You have access

  Hepatocellular Organic Anion–Transporting Polypeptides (OATPs) and Multidrug Resistance–Associated Protein 2 (MRP2) Are Inhibited by Silibinin

  Katrin Wlcek, Fabienne Koller, Peter Ferenci and Bruno Stieger

  Drug Metabolism and Disposition August 2013, 41 (8) 1522-1528; DOI: https://doi.org/10.1124/dmd.113.051037
• You have access

  Glucuronidation of a Sarpogrelate Active Metabolite Is Mediated by UDP-Glucuronosyltransferases 1A4, 1A9, and 2B4

  Hyo-Ji Kim, Eun Sook Jeong, Kyung-Ah Seo, Kye Jung Shin, Yeon Jae Choi, Su-Jun Lee, Jong Lyul Ghim, Dong-Ryul Sohn, Jae-Gook Shin and Dong-Hyun Kim

  Drug Metabolism and Disposition August 2013, 41 (8) 1529-1537; DOI: https://doi.org/10.1124/dmd.113.051862
• You have access

  Genetic Variation in Aldo-Keto Reductase 1D1 (AKR1D1) Affects the Expression and Activity of Multiple Cytochrome P450s

  Amarjit S. Chaudhry, Ranjit K. Thirumaran, Kazuto Yasuda, Xia Yang, Yiping Fan, Stephen C. Strom and Erin G. Schuetz

  Drug Metabolism and Disposition August 2013, 41 (8) 1538-1547; DOI: https://doi.org/10.1124/dmd.113.051672
• You have access

  Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing Drugs

  Youssef Daali, Philippe Millet, Pierre Dayer and Catherine M. Pastor

  Drug Metabolism and Disposition August 2013, 41 (8) 1548-1556; DOI: https://doi.org/10.1124/dmd.113.051870
• You have access

  Nanoparticle Formulation of a Poorly Soluble Cannabinoid Receptor 1 Antagonist Improves Absorption by Rat and Human Intestine

  Sanna Siissalo, Hans de Waard, Marina H. de Jager, Rose Hayeshi, Henderik W. Frijlink, Wouter L.J. Hinrichs, Heike Dinter-Heidorn, Annie van Dam, Johannes H. Proost, Geny M.M. Groothuis and Inge A.M. de Graaf

  Drug Metabolism and Disposition August 2013, 41 (8) 1557-1565; DOI: https://doi.org/10.1124/dmd.112.049585
• You have access

  Effect of CYP3A5 Expression on the Inhibition of CYP3A-Catalyzed Drug Metabolism: Impact on Modeling CYP3A-Mediated Drug-Drug Interactions

  Yoshiyuki Shirasaka, Shu-Ying Chang, Mary F. Grubb, Chi-Chi Peng, Kenneth E. Thummel, Nina Isoherranen and A. David Rodrigues

  Drug Metabolism and Disposition August 2013, 41 (8) 1566-1574; DOI: https://doi.org/10.1124/dmd.112.049940
• You have access

  In Vitro Characterization of Axitinib Interactions with Human Efflux and Hepatic Uptake Transporters: Implications for Disposition and Drug Interactions

  Eric L. Reyner, Samantha Sevidal, Mark A. West, Andrea Clouser-Roche, Sascha Freiwald, Katherine Fenner, Mohammed Ullah, Caroline A. Lee and Bill J. Smith

  Drug Metabolism and Disposition August 2013, 41 (8) 1575-1583; DOI: https://doi.org/10.1124/dmd.113.051193
• You have access

  Pharmacokinetic Study of the Structural Components of Adenosine Diphosphate-Encapsulated Liposomes Coated with Fibrinogen γ-Chain Dodecapeptide as a Synthetic Platelet Substitute

  Kazuaki Taguchi, Hayato Ujihira, Shigeru Ogaki, Hiroshi Watanabe, Atsushi Fujiyama, Mami Doi, Yosuke Okamura, Shinji Takeoka, Yasuo Ikeda, Makoto Handa, Masaki Otagiri and Toru Maruyama

  Drug Metabolism and Disposition August 2013, 41 (8) 1584-1591; DOI: https://doi.org/10.1124/dmd.112.050005
• You have access

  Effect of P-Glycoprotein and Breast Cancer Resistance Protein Inhibition on the Pharmacokinetics of Sunitinib in Rats

  Sachiko Kunimatsu, Tomoyuki Mizuno, Masahide Fukudo and Toshiya Katsura

  Drug Metabolism and Disposition August 2013, 41 (8) 1592-1597; DOI: https://doi.org/10.1124/dmd.112.050286