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Index by author

January 01, 2014; Volume 42,Issue 1

A

  1. Ambudkar, Suresh V.

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

B

  1. Backes, Wayne L.

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  2. Bae, Soo Hyeon

    1. Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes
      Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim and Soo Kyung Bae
      Drug Metabolism and Disposition January 2014, 42 (1) 33-39; DOI: https://doi.org/10.1124/dmd.113.054296

  3. Bae, Soo Kyung

    1. Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes
      Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim and Soo Kyung Bae
      Drug Metabolism and Disposition January 2014, 42 (1) 33-39; DOI: https://doi.org/10.1124/dmd.113.054296

  4. Bao, Jing Q.

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  5. Baumann, Michael H.

    1. Nonlinear Pharmacokinetics of (±)3,4-Methylenedioxymethamphetamine (MDMA) and Its Pharmacodynamic Consequences in the Rat
      Marta Concheiro, Michael H. Baumann, Karl B. Scheidweiler, Richard B. Rothman, Gina F. Marrone and Marilyn A. Huestis
      Drug Metabolism and Disposition January 2014, 42 (1) 119-125; DOI: https://doi.org/10.1124/dmd.113.053678

  6. Bi, Hui Chang

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

C

  1. Cao, Yunfeng

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

  2. Chanteux, Hugues

    1. In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug
      Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
      Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

  3. Chen, Xiao

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  4. Cherrington, Nathan J.

    1. Localization of Multidrug Resistance-Associated Proteins along the Blood-Testis Barrier in Rat, Macaque, and Human Testis
      David M. Klein, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2014, 42 (1) 89-93; DOI: https://doi.org/10.1124/dmd.113.054577

  5. Cho, Doo-Yeoun

    1. Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes
      Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim and Soo Kyung Bae
      Drug Metabolism and Disposition January 2014, 42 (1) 33-39; DOI: https://doi.org/10.1124/dmd.113.054296

  6. Choi, Chang-Soo

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  7. Concheiro, Marta

    1. Nonlinear Pharmacokinetics of (±)3,4-Methylenedioxymethamphetamine (MDMA) and Its Pharmacodynamic Consequences in the Rat
      Marta Concheiro, Michael H. Baumann, Karl B. Scheidweiler, Richard B. Rothman, Gina F. Marrone and Marilyn A. Huestis
      Drug Metabolism and Disposition January 2014, 42 (1) 119-125; DOI: https://doi.org/10.1124/dmd.113.053678

  8. Connick, J. Patrick

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  9. Court, Michael H.

    1. Candidate Gene Polymorphisms in Patients with Acetaminophen-Induced Acute Liver Failure
      Michael H. Court, Inga Peter, Suwagmani Hazarika, Magdalini Vasiadi, David J. Greenblatt, William M. Lee and The Acute Liver Failure Study Group
      Drug Metabolism and Disposition January 2014, 42 (1) 28-32; DOI: https://doi.org/10.1124/dmd.113.053546

  10. Cummings, Richard D.

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

D

  1. D’Agostino, Jaime

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  2. Delatour, Claude

    1. In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug
      Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
      Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

  3. Desai, Manoj C.

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  4. Ding, Xinxin

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

E

  1. Estrada, D. Fernando

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  2. Evers, Raymond

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

F

  1. Fallon, John K.

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  2. Finn, Robert D.

    1. A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice
      Colin J. Henderson, Lesley A. McLaughlin, Robert D. Finn, Sebastien Ronseaux, Yury Kapelyukh and C. Roland Wolf
      Drug Metabolism and Disposition January 2014, 42 (1) 70-77; DOI: https://doi.org/10.1124/dmd.113.055277

  3. Floehr, Tilman

    1. Tissue-Specific Metabolism of Benzo[a]pyrene in Rainbow Trout (Oncorhynchus mykiss): A Comparison between the Liver and Immune Organs
      Anja-Maria Möller, Corinna Hermsen, Tilman Floehr, Marja H. Lamoree and Helmut Segner
      Drug Metabolism and Disposition January 2014, 42 (1) 111-118; DOI: https://doi.org/10.1124/dmd.113.053777

  4. Fujioka, Takashi

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  5. Fukami, Tatsuki

    1. Evaluation and Mechanistic Analysis of the Cytotoxicity of the Acyl Glucuronide of Nonsteroidal Anti-Inflammatory Drugs
      Taishi Miyashita, Kento Kimura, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2014, 42 (1) 1-8; DOI: https://doi.org/10.1124/dmd.113.054478

G

  1. Ge, Guangbo

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

  2. Ghim, Jong Lyul

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  3. Ghose, Romi

    1. Role of Constitutive Androstane Receptor in Toll-Like Receptor-Mediated Regulation of Gene Expression of Hepatic Drug-Metabolizing Enzymes and Transporters
      Pranav Shah, Tao Guo, David D. Moore and Romi Ghose
      Drug Metabolism and Disposition January 2014, 42 (1) 172-181; DOI: https://doi.org/10.1124/dmd.113.053850

  4. Greenblatt, David J.

    1. Candidate Gene Polymorphisms in Patients with Acetaminophen-Induced Acute Liver Failure
      Michael H. Court, Inga Peter, Suwagmani Hazarika, Magdalini Vasiadi, David J. Greenblatt, William M. Lee and The Acute Liver Failure Study Group
      Drug Metabolism and Disposition January 2014, 42 (1) 28-32; DOI: https://doi.org/10.1124/dmd.113.053546

  5. Guo, Peixuan

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  6. Guo, Tao

    1. Role of Constitutive Androstane Receptor in Toll-Like Receptor-Mediated Regulation of Gene Expression of Hepatic Drug-Metabolizing Enzymes and Transporters
      Pranav Shah, Tao Guo, David D. Moore and Romi Ghose
      Drug Metabolism and Disposition January 2014, 42 (1) 172-181; DOI: https://doi.org/10.1124/dmd.113.053850

  7. Gupta, Anshul

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

  8. Gwak, Hye Sun

    1. Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor
      Sunny Park, Na Ra Lee, Kyung Eun Lee, Jin Young Park, Young Ju Kim and Hye Sun Gwak
      Drug Metabolism and Disposition January 2014, 42 (1) 40-43; DOI: https://doi.org/10.1124/dmd.113.054106

H

  1. Hardy, Klarissa D.

    1. Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
      Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie and Sidney D. Nelson
      Drug Metabolism and Disposition January 2014, 42 (1) 162-171; DOI: https://doi.org/10.1124/dmd.113.054817

  2. Hazarika, Suwagmani

    1. Candidate Gene Polymorphisms in Patients with Acetaminophen-Induced Acute Liver Failure
      Michael H. Court, Inga Peter, Suwagmani Hazarika, Magdalini Vasiadi, David J. Greenblatt, William M. Lee and The Acute Liver Failure Study Group
      Drug Metabolism and Disposition January 2014, 42 (1) 28-32; DOI: https://doi.org/10.1124/dmd.113.053546

  3. He, Zhi-Xu

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  4. Henderson, Colin J.

    1. A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice
      Colin J. Henderson, Lesley A. McLaughlin, Robert D. Finn, Sebastien Ronseaux, Yury Kapelyukh and C. Roland Wolf
      Drug Metabolism and Disposition January 2014, 42 (1) 70-77; DOI: https://doi.org/10.1124/dmd.113.055277

  5. Hermsen, Corinna

    1. Tissue-Specific Metabolism of Benzo[a]pyrene in Rainbow Trout (Oncorhynchus mykiss): A Comparison between the Liver and Immune Organs
      Anja-Maria Möller, Corinna Hermsen, Tilman Floehr, Marja H. Lamoree and Helmut Segner
      Drug Metabolism and Disposition January 2014, 42 (1) 111-118; DOI: https://doi.org/10.1124/dmd.113.053777

  6. Higgins, J. William

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  7. Hong, James Y.

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

  8. Hop, Cornelis E. C. A.

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

  9. Hu, Jinping

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  10. Huang, Min

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  11. Huestis, Marilyn A.

    1. Nonlinear Pharmacokinetics of (±)3,4-Methylenedioxymethamphetamine (MDMA) and Its Pharmacodynamic Consequences in the Rat
      Marta Concheiro, Michael H. Baumann, Karl B. Scheidweiler, Richard B. Rothman, Gina F. Marrone and Marilyn A. Huestis
      Drug Metabolism and Disposition January 2014, 42 (1) 119-125; DOI: https://doi.org/10.1124/dmd.113.053678

I

  1. Itoh, Hiroki

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

J

  1. Jeong, Eun Sook

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  2. Johnson, Eric F.

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

K

  1. Kapelyukh, Yury

    1. A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice
      Colin J. Henderson, Lesley A. McLaughlin, Robert D. Finn, Sebastien Ronseaux, Yury Kapelyukh and C. Roland Wolf
      Drug Metabolism and Disposition January 2014, 42 (1) 70-77; DOI: https://doi.org/10.1124/dmd.113.055277

  2. Kawasaki, Kanako

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  3. Ke, Alice B.

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  4. Kim, Bom-Taeck

    1. Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes
      Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim and Soo Kyung Bae
      Drug Metabolism and Disposition January 2014, 42 (1) 33-39; DOI: https://doi.org/10.1124/dmd.113.054296

  5. Kim, Dong-Hyun

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  6. Kim, Min-Jung

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  7. Kim, Yang Weon

    1. Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes
      Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim and Soo Kyung Bae
      Drug Metabolism and Disposition January 2014, 42 (1) 33-39; DOI: https://doi.org/10.1124/dmd.113.054296

  8. Kim, Young Ju

    1. Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor
      Sunny Park, Na Ra Lee, Kyung Eun Lee, Jin Young Park, Young Ju Kim and Hye Sun Gwak
      Drug Metabolism and Disposition January 2014, 42 (1) 40-43; DOI: https://doi.org/10.1124/dmd.113.054106

  9. Kimura, Kento

    1. Evaluation and Mechanistic Analysis of the Cytotoxicity of the Acyl Glucuronide of Nonsteroidal Anti-Inflammatory Drugs
      Taishi Miyashita, Kento Kimura, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2014, 42 (1) 1-8; DOI: https://doi.org/10.1124/dmd.113.054478

  10. Kishino, Satoshi

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  11. Klein, David M.

    1. Localization of Multidrug Resistance-Associated Proteins along the Blood-Testis Barrier in Rat, Macaque, and Human Testis
      David M. Klein, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2014, 42 (1) 89-93; DOI: https://doi.org/10.1124/dmd.113.054577

L

  1. Lamoree, Marja H.

    1. Tissue-Specific Metabolism of Benzo[a]pyrene in Rainbow Trout (Oncorhynchus mykiss): A Comparison between the Liver and Immune Organs
      Anja-Maria Möller, Corinna Hermsen, Tilman Floehr, Marja H. Lamoree and Helmut Segner
      Drug Metabolism and Disposition January 2014, 42 (1) 111-118; DOI: https://doi.org/10.1124/dmd.113.053777

  2. Laurence, Jennifer S.

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  3. Lee, Choon-Myung

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

  4. Lee, Joeng Kee

    1. Selective Inhibition of Cytochrome P450 2D6 by Sarpogrelate and Its Active Metabolite, M-1, in Human Liver Microsomes
      Doo-Yeoun Cho, Soo Hyeon Bae, Joeng Kee Lee, Yang Weon Kim, Bom-Taeck Kim and Soo Kyung Bae
      Drug Metabolism and Disposition January 2014, 42 (1) 33-39; DOI: https://doi.org/10.1124/dmd.113.054296

  5. Lee, Kyung Eun

    1. Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor
      Sunny Park, Na Ra Lee, Kyung Eun Lee, Jin Young Park, Young Ju Kim and Hye Sun Gwak
      Drug Metabolism and Disposition January 2014, 42 (1) 40-43; DOI: https://doi.org/10.1124/dmd.113.054106

  6. Lee, Na Ra

    1. Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor
      Sunny Park, Na Ra Lee, Kyung Eun Lee, Jin Young Park, Young Ju Kim and Hye Sun Gwak
      Drug Metabolism and Disposition January 2014, 42 (1) 40-43; DOI: https://doi.org/10.1124/dmd.113.054106

  7. Lee, Su-Jun

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  8. Lee, William M.

    1. Candidate Gene Polymorphisms in Patients with Acetaminophen-Induced Acute Liver Failure
      Michael H. Court, Inga Peter, Suwagmani Hazarika, Magdalini Vasiadi, David J. Greenblatt, William M. Lee and The Acute Liver Failure Study Group
      Drug Metabolism and Disposition January 2014, 42 (1) 28-32; DOI: https://doi.org/10.1124/dmd.113.053546

  9. Li, Jia Li

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  10. Li, Lei

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  11. Li, Minghua

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  12. Li, Yan

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  13. Linnet, Kristian

    1. In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors
      Ragnar Thomsen, Henrik B. Rasmussen, Kristian Linnet and The INDICES Consortium
      Drug Metabolism and Disposition January 2014, 42 (1) 126-133; DOI: https://doi.org/10.1124/dmd.113.053512

  14. Liu, Yong

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

M

  1. Manro, Jason R.

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  2. Marrone, Gina F.

    1. Nonlinear Pharmacokinetics of (±)3,4-Methylenedioxymethamphetamine (MDMA) and Its Pharmacodynamic Consequences in the Rat
      Marta Concheiro, Michael H. Baumann, Karl B. Scheidweiler, Richard B. Rothman, Gina F. Marrone and Marilyn A. Huestis
      Drug Metabolism and Disposition January 2014, 42 (1) 119-125; DOI: https://doi.org/10.1124/dmd.113.053678

  3. McLaughlin, Lesley A.

    1. A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice
      Colin J. Henderson, Lesley A. McLaughlin, Robert D. Finn, Sebastien Ronseaux, Yury Kapelyukh and C. Roland Wolf
      Drug Metabolism and Disposition January 2014, 42 (1) 70-77; DOI: https://doi.org/10.1124/dmd.113.055277

  4. Merrell, Matthew D.

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

  5. Mimata, Hiromitsu

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  6. Mimche, Sylvie M.

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

  7. Miyashita, Taishi

    1. Evaluation and Mechanistic Analysis of the Cytotoxicity of the Acyl Glucuronide of Nonsteroidal Anti-Inflammatory Drugs
      Taishi Miyashita, Kento Kimura, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2014, 42 (1) 1-8; DOI: https://doi.org/10.1124/dmd.113.054478

  8. Möller, Anja-Maria

    1. Tissue-Specific Metabolism of Benzo[a]pyrene in Rainbow Trout (Oncorhynchus mykiss): A Comparison between the Liver and Immune Organs
      Anja-Maria Möller, Corinna Hermsen, Tilman Floehr, Marja H. Lamoree and Helmut Segner
      Drug Metabolism and Disposition January 2014, 42 (1) 111-118; DOI: https://doi.org/10.1124/dmd.113.053777

  9. Moore, David D.

    1. Role of Constitutive Androstane Receptor in Toll-Like Receptor-Mediated Regulation of Gene Expression of Hepatic Drug-Metabolizing Enzymes and Transporters
      Pranav Shah, Tao Guo, David D. Moore and Romi Ghose
      Drug Metabolism and Disposition January 2014, 42 (1) 172-181; DOI: https://doi.org/10.1124/dmd.113.053850

  10. Morgan, Edward T.

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

  11. Murray, John W.

    1. Oatp1a1 Requires PDZK1 to Traffic to the Plasma Membrane by Selective Recruitment of Microtubule-Based Motor Proteins
      Wen-Jun Wang, John W. Murray and Allan W. Wolkoff
      Drug Metabolism and Disposition January 2014, 42 (1) 62-69; DOI: https://doi.org/10.1124/dmd.113.054536

N

  1. Nakajima, Miki

    1. Evaluation and Mechanistic Analysis of the Cytotoxicity of the Acyl Glucuronide of Nonsteroidal Anti-Inflammatory Drugs
      Taishi Miyashita, Kento Kimura, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2014, 42 (1) 1-8; DOI: https://doi.org/10.1124/dmd.113.054478

  2. Nelson, Sidney D.

    1. Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
      Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie and Sidney D. Nelson
      Drug Metabolism and Disposition January 2014, 42 (1) 162-171; DOI: https://doi.org/10.1124/dmd.113.054817

  3. Nicolas, Jean-Marie

    1. In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug
      Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
      Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

  4. Nyagode, Beatrice A.

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

O

  1. Ohno, Keiko

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

P

  1. Papageorgiou, Ioannis

    1. Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
      Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie and Sidney D. Nelson
      Drug Metabolism and Disposition January 2014, 42 (1) 162-171; DOI: https://doi.org/10.1124/dmd.113.054817

  2. Park, Jin Young

    1. Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor
      Sunny Park, Na Ra Lee, Kyung Eun Lee, Jin Young Park, Young Ju Kim and Hye Sun Gwak
      Drug Metabolism and Disposition January 2014, 42 (1) 40-43; DOI: https://doi.org/10.1124/dmd.113.054106

  3. Park, Jung-Soon

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  4. Park, Sunny

    1. Effects of Single-Nucleotide Polymorphisms of FMO3 and FMO6 Genes on Pharmacokinetic Characteristics of Sulindac Sulfide in Premature Labor
      Sunny Park, Na Ra Lee, Kyung Eun Lee, Jin Young Park, Young Ju Kim and Hye Sun Gwak
      Drug Metabolism and Disposition January 2014, 42 (1) 40-43; DOI: https://doi.org/10.1124/dmd.113.054106

  5. Peter, Inga

    1. Candidate Gene Polymorphisms in Patients with Acetaminophen-Induced Acute Liver Failure
      Michael H. Court, Inga Peter, Suwagmani Hazarika, Magdalini Vasiadi, David J. Greenblatt, William M. Lee and The Acute Liver Failure Study Group
      Drug Metabolism and Disposition January 2014, 42 (1) 28-32; DOI: https://doi.org/10.1124/dmd.113.053546

  6. Prakash, Chandra

    1. In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug
      Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
      Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

  7. Prasad, Bhagwat

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

  8. Prasanphanich, Nina S.

    1. Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection
      Sylvie M. Mimche, Beatrice A. Nyagode, Matthew D. Merrell, Choon-Myung Lee, Nina S. Prasanphanich, Richard D. Cummings and Edward T. Morgan
      Drug Metabolism and Disposition January 2014, 42 (1) 134-140; DOI: https://doi.org/10.1124/dmd.113.054957

Q

  1. Qin, Xiao Ling

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

R

  1. Rasmussen, Henrik B.

    1. In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors
      Ragnar Thomsen, Henrik B. Rasmussen, Kristian Linnet and The INDICES Consortium
      Drug Metabolism and Disposition January 2014, 42 (1) 126-133; DOI: https://doi.org/10.1124/dmd.113.053512

  2. Reed, James R.

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  3. Rettie, Allan E.

    1. Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
      Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie and Sidney D. Nelson
      Drug Metabolism and Disposition January 2014, 42 (1) 162-171; DOI: https://doi.org/10.1124/dmd.113.054817

  4. Ronseaux, Sebastien

    1. A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice
      Colin J. Henderson, Lesley A. McLaughlin, Robert D. Finn, Sebastien Ronseaux, Yury Kapelyukh and C. Roland Wolf
      Drug Metabolism and Disposition January 2014, 42 (1) 70-77; DOI: https://doi.org/10.1124/dmd.113.055277

  5. Rosa, Maria

    1. In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug
      Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
      Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

  6. Rothman, Richard B.

    1. Nonlinear Pharmacokinetics of (±)3,4-Methylenedioxymethamphetamine (MDMA) and Its Pharmacodynamic Consequences in the Rat
      Marta Concheiro, Michael H. Baumann, Karl B. Scheidweiler, Richard B. Rothman, Gina F. Marrone and Marilyn A. Huestis
      Drug Metabolism and Disposition January 2014, 42 (1) 119-125; DOI: https://doi.org/10.1124/dmd.113.053678

S

  1. Salphati, Laurent

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

  2. Sato, Fuminori

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  3. Sato, Yuhki

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  4. Sato, Yukie

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

  5. Scheidweiler, Karl B.

    1. Nonlinear Pharmacokinetics of (±)3,4-Methylenedioxymethamphetamine (MDMA) and Its Pharmacodynamic Consequences in the Rat
      Marta Concheiro, Michael H. Baumann, Karl B. Scheidweiler, Richard B. Rothman, Gina F. Marrone and Marilyn A. Huestis
      Drug Metabolism and Disposition January 2014, 42 (1) 119-125; DOI: https://doi.org/10.1124/dmd.113.053678

  6. Scott, Emily E.

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  7. Segner, Helmut

    1. Tissue-Specific Metabolism of Benzo[a]pyrene in Rainbow Trout (Oncorhynchus mykiss): A Comparison between the Liver and Immune Organs
      Anja-Maria Möller, Corinna Hermsen, Tilman Floehr, Marja H. Lamoree and Helmut Segner
      Drug Metabolism and Disposition January 2014, 42 (1) 111-118; DOI: https://doi.org/10.1124/dmd.113.053777

  8. Shah, Pranav

    1. Role of Constitutive Androstane Receptor in Toll-Like Receptor-Mediated Regulation of Gene Expression of Hepatic Drug-Metabolizing Enzymes and Transporters
      Pranav Shah, Tao Guo, David D. Moore and Romi Ghose
      Drug Metabolism and Disposition January 2014, 42 (1) 172-181; DOI: https://doi.org/10.1124/dmd.113.053850

  9. Sheng, Li

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  10. Shin, Jae-Gook

    1. Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
      Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
      Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017

  11. Shukla, Suneet

    1. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

  12. Smith, Philip C.

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  13. Smith, Steven

    1. In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug
      Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
      Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

  14. Suzuki, Yosuke

    1. Association of Plasma Concentration of 4β-Hydroxycholesterol with CYP3A5 Polymorphism and Plasma Concentration of Indoxyl Sulfate in Stable Kidney Transplant Recipients
      Yosuke Suzuki, Hiroki Itoh, Takashi Fujioka, Fuminori Sato, Kanako Kawasaki, Yukie Sato, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata and Satoshi Kishino
      Drug Metabolism and Disposition January 2014, 42 (1) 105-110; DOI: https://doi.org/10.1124/dmd.113.054171

T

  1. Thomsen, Ragnar

    1. In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors
      Ragnar Thomsen, Henrik B. Rasmussen, Kristian Linnet and The INDICES Consortium
      Drug Metabolism and Disposition January 2014, 42 (1) 126-133; DOI: https://doi.org/10.1124/dmd.113.053512

U

  1. Unadkat, Jashvant D.

    1. Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
      Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie and Sidney D. Nelson
      Drug Metabolism and Disposition January 2014, 42 (1) 162-171; DOI: https://doi.org/10.1124/dmd.113.054817
    2. Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex
      Bhagwat Prasad, Raymond Evers, Anshul Gupta, Cornelis E. C. A. Hop, Laurent Salphati, Suneet Shukla, Suresh V. Ambudkar and Jashvant D. Unadkat
      Drug Metabolism and Disposition January 2014, 42 (1) 78-88; DOI: https://doi.org/10.1124/dmd.113.053819

V

  1. Vasiadi, Magdalini

    1. Candidate Gene Polymorphisms in Patients with Acetaminophen-Induced Acute Liver Failure
      Michael H. Court, Inga Peter, Suwagmani Hazarika, Magdalini Vasiadi, David J. Greenblatt, William M. Lee and The Acute Liver Failure Study Group
      Drug Metabolism and Disposition January 2014, 42 (1) 28-32; DOI: https://doi.org/10.1124/dmd.113.053546

W

  1. Wahlin, Michelle D.

    1. Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor–Dependent Hepatotoxicity: Induction of CYP3A4 Enhances the Cytotoxicity of Lapatinib in HepaRG Cells
      Klarissa D. Hardy, Michelle D. Wahlin, Ioannis Papageorgiou, Jashvant D. Unadkat, Allan E. Rettie and Sidney D. Nelson
      Drug Metabolism and Disposition January 2014, 42 (1) 162-171; DOI: https://doi.org/10.1124/dmd.113.054817

  2. Wang, Chang Xi

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  3. Wang, Wen-Jun

    1. Oatp1a1 Requires PDZK1 to Traffic to the Plasma Membrane by Selective Recruitment of Microtubule-Based Motor Proteins
      Wen-Jun Wang, John W. Murray and Allan W. Wolkoff
      Drug Metabolism and Disposition January 2014, 42 (1) 62-69; DOI: https://doi.org/10.1124/dmd.113.054536

  4. Wang, Xue Ding

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  5. Wang, Ying

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892
    2. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  6. Wolf, C. Roland

    1. A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice
      Colin J. Henderson, Lesley A. McLaughlin, Robert D. Finn, Sebastien Ronseaux, Yury Kapelyukh and C. Roland Wolf
      Drug Metabolism and Disposition January 2014, 42 (1) 70-77; DOI: https://doi.org/10.1124/dmd.113.055277

  7. Wolkoff, Allan W.

    1. Oatp1a1 Requires PDZK1 to Traffic to the Plasma Membrane by Selective Recruitment of Microtubule-Based Motor Proteins
      Wen-Jun Wang, John W. Murray and Allan W. Wolkoff
      Drug Metabolism and Disposition January 2014, 42 (1) 62-69; DOI: https://doi.org/10.1124/dmd.113.054536

  8. Wright, Stephen H.

    1. Localization of Multidrug Resistance-Associated Proteins along the Blood-Testis Barrier in Rat, Macaque, and Human Testis
      David M. Klein, Stephen H. Wright and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2014, 42 (1) 89-93; DOI: https://doi.org/10.1124/dmd.113.054577

  9. Wu, Jingjing

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

X

  1. Xie, Fang

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  2. Xu, Lianhong

    1. Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges
      Eric F. Johnson, J. Patrick Connick, James R. Reed, Wayne L. Backes, Manoj C. Desai, Lianhong Xu, D. Fernando Estrada, Jennifer S. Laurence and Emily E. Scott
      Drug Metabolism and Disposition January 2014, 42 (1) 9-22; DOI: https://doi.org/10.1124/dmd.113.054627

  3. Xue, Xin Ping

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

Y

  1. Yang, Hui

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  2. Yang, Ling

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

  3. Yang, Tianxin

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  4. Yang, Yinxue

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  5. Yokoi, Tsuyoshi

    1. Evaluation and Mechanistic Analysis of the Cytotoxicity of the Acyl Glucuronide of Nonsteroidal Anti-Inflammatory Drugs
      Taishi Miyashita, Kento Kimura, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition January 2014, 42 (1) 1-8; DOI: https://doi.org/10.1124/dmd.113.054478

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein
      J. William Higgins, Jing Q. Bao, Alice B. Ke, Jason R. Manro, John K. Fallon, Philip C. Smith and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition January 2014, 42 (1) 182-192; DOI: https://doi.org/10.1124/dmd.113.054783

  2. Zhang, Xueji

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  3. Zhang, Yanyan

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884

  4. Zhong, Guo Ping

    1. In Vivo to In Vitro Effects of Six Bioactive Lignans of Wuzhi Tablet (Schisandra Sphenanthera Extract) on the CYP3A/P-glycoprotein–Mediated Absorption and Metabolism of Tacrolimus
      Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Ying Wang, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang and Hui Chang Bi
      Drug Metabolism and Disposition January 2014, 42 (1) 193-199; DOI: https://doi.org/10.1124/dmd.113.053892

  5. Zhou, Shu-Feng

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  6. Zhou, Xin

    1. Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
      Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li and Xinxin Ding
      Drug Metabolism and Disposition January 2014, 42 (1) 23-27; DOI: https://doi.org/10.1124/dmd.113.054429

  7. Zhou, Zhi-Wei

    1. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in HepG2 Cells and Primary Human Hepatocytes through Downregulation of the Nuclear Receptor Corepressor Dosage-Sensitive Sex-Reversal Adrenal Hypoplasia Congenital Critical Region on the X Chromosome, Gene 1 (DAX-1)
      Minghua Li, Yinxue Yang, Zhi-Xu He, Zhi-Wei Zhou, Tianxin Yang, Peixuan Guo, Xueji Zhang and Shu-Feng Zhou
      Drug Metabolism and Disposition January 2014, 42 (1) 44-61; DOI: https://doi.org/10.1124/dmd.113.052670

  8. Zhu, Liangliang

    1. Deoxyschizandrin, a Naturally Occurring Lignan, Is a Specific Probe Substrate of Human Cytochrome P450 3A
      Jingjing Wu, Yunfeng Cao, Yanyan Zhang, Yong Liu, James Y. Hong, Liangliang Zhu, Guangbo Ge and Ling Yang
      Drug Metabolism and Disposition January 2014, 42 (1) 94-104; DOI: https://doi.org/10.1124/dmd.113.053884
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