Research ArticleArticle
Multiple Cytochrome P450 Isoforms Are Involved in the Generation of a Pharmacologically Active Thiol Metabolite, whereas Paraoxonase 1 and Carboxylesterase 1 Catalyze the Formation of a Thiol Metabolite Isomer from Ticlopidine
Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
Drug Metabolism and Disposition January 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017
Min-Jung Kim
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Eun Sook Jeong
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Jung-Soon Park
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Su-Jun Lee
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Jong Lyul Ghim
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Chang-Soo Choi
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Jae-Gook Shin
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
Dong-Hyun Kim
Department of Pharmacology and PharmacoGenomics Research Center, College of Medicine (M.-J.K., E.S.J, J.-S.P., S.-J.L., J.L.G, J.-G.S., D.-H.K.), and Department of General Surgery, Busan Paik Hospital (C.-S.C.), Inje University, Busan, South Korea
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Research ArticleArticle
Metabolic Conversion of Ticlopidine to Thiol Metabolites.
Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
Drug Metabolism and Disposition January 1, 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017
Research ArticleArticle
Metabolic Conversion of Ticlopidine to Thiol Metabolites.
Min-Jung Kim, Eun Sook Jeong, Jung-Soon Park, Su-Jun Lee, Jong Lyul Ghim, Chang-Soo Choi, Jae-Gook Shin and Dong-Hyun Kim
Drug Metabolism and Disposition January 1, 2014, 42 (1) 141-152; DOI: https://doi.org/10.1124/dmd.113.053017
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