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Research ArticleArticle

In Vitro Hydrolysis and Transesterification of CDP323, an α4β1/α4β7 Integrin Antagonist Ester Prodrug

Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
Drug Metabolism and Disposition January 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049

Article Information

vol. 42 no. 1 153-161
DOI 
https://doi.org/10.1124/dmd.113.054049
PubMed 
24179032
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 7, 2013
  • Accepted October 31, 2013
  • Published online December 12, 2013.

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Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hugues Chanteux,
  2. Maria Rosa,
  3. Claude Delatour,
  4. Chandra Prakash,
  5. Steven Smith, and
  6. Jean-Marie Nicolas
  1. UCB Pharma SA, Non Clinical DMPK, Braine l’Alleud, Belgium (H.C., M.R., C.D., S.S., J.M.N.); Biogenidec, Cambridge, Massachusetts (C.P.)
  1. Address correspondence to:
    Dr. Hugues Chanteux, Chemin du Foriest, B-1420 Braine-l’Alleud, Belgium. E-mail address: hugues.chanteux{at}ucb.com
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Research ArticleArticle

Hydrolysis and Transesterification of CDP323 Prodrug

Hugues Chanteux, Maria Rosa, Claude Delatour, Chandra Prakash, Steven Smith and Jean-Marie Nicolas
Drug Metabolism and Disposition January 1, 2014, 42 (1) 153-161; DOI: https://doi.org/10.1124/dmd.113.054049
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