Index by author
October 01, 2014; Volume 42,Issue 10
A
Abdel-Rahman, Susan M.
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
Ahmed, Mahmoud S.
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
Albertin, Giovanna
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Albertoni, Laura
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Asher, Constance
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
B
Barton, Hugh A.
- You have accessPhysiologically Based Pharmacokinetic Prediction of Telmisartan in HumanRui Li, Avijit Ghosh, Tristan S. Maurer, Emi Kimoto and Hugh A. BartonDrug Metabolism and Disposition October 2014, 42 (10) 1646-1655; DOI: https://doi.org/10.1124/dmd.114.058461
Bauer, Cassondra
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
Bauman, Jonathan N.
- You have accessBiosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism StudiesGregory S. Walker, Jonathan N. Bauman, Tim F. Ryder, Evan B. Smith, Douglas K. Spracklin and R. Scott ObachDrug Metabolism and Disposition October 2014, 42 (10) 1627-1639; DOI: https://doi.org/10.1124/dmd.114.059204
Behshad, Elham
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Bernstein, Hilary J.
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
Boer, Jason
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Bova, Sergio
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Brinda, Bryan J.
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
Burn, Timothy
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
C
Cerny, Matthew A.
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
Chavin, Kenneth D.
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
Chen, Gang
- You have accessIdentification of Diet-Derived Constituents as Potent Inhibitors of Intestinal GlucuronidationBrandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition October 2014, 42 (10) 1675-1683; DOI: https://doi.org/10.1124/dmd.114.059451
Chen, Kaixian
- You have accessMetabolism of Diosbulbin B In Vitro and In Vivo in Rats: Formation of Reactive Metabolites and Human Enzymes InvolvedBaohua Yang, Wei Liu, Kaixian Chen, Zhengtao Wang and Changhong WangDrug Metabolism and Disposition October 2014, 42 (10) 1737-1750; DOI: https://doi.org/10.1124/dmd.114.058222
Collier, Paul
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
D
De Martin, Sara
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Diamond, Sharon
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
E
Eksterowicz, John
- You have accessCharacterization of the Active Site Properties of CYP4F12John Eksterowicz, Dan A. Rock, Brooke M. Rock, Larry C. Wienkers and Robert S. FotiDrug Metabolism and Disposition October 2014, 42 (10) 1698-1707; DOI: https://doi.org/10.1124/dmd.114.059626
F
Feng, Bo
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Foti, Robert S.
- You have accessCharacterization of the Active Site Properties of CYP4F12John Eksterowicz, Dan A. Rock, Brooke M. Rock, Larry C. Wienkers and Robert S. FotiDrug Metabolism and Disposition October 2014, 42 (10) 1698-1707; DOI: https://doi.org/10.1124/dmd.114.059626
Frederick, Kosea
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
Frye, Reginald F.
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
Fuchs, Holger
- You have accessBrain Penetration of WEB 2086 (Apafant) and Dantrolene in Mdr1a (P-Glycoprotein) and Bcrp Knockout RatsHolger Fuchs, Wataru Kishimoto, Dietmar Gansser, Paul Tanswell and Naoki IshiguroDrug Metabolism and Disposition October 2014, 42 (10) 1761-1765; DOI: https://doi.org/10.1124/dmd.114.058545
G
Gabbia, Daniela
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Gansser, Dietmar
- You have accessBrain Penetration of WEB 2086 (Apafant) and Dantrolene in Mdr1a (P-Glycoprotein) and Bcrp Knockout RatsHolger Fuchs, Wataru Kishimoto, Dietmar Gansser, Paul Tanswell and Naoki IshiguroDrug Metabolism and Disposition October 2014, 42 (10) 1761-1765; DOI: https://doi.org/10.1124/dmd.114.058545
Gao, Huiyuan
- You have accessCytochrome P450–Mediated Metabolic Activation of Diosbulbin BDongju Lin, Chunyan Li, Ying Peng, Huiyuan Gao and Jiang ZhengDrug Metabolism and Disposition October 2014, 42 (10) 1727-1736; DOI: https://doi.org/10.1124/dmd.114.059261
Gardiner, Christine
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Ghosh, Avijit
- You have accessPhysiologically Based Pharmacokinetic Prediction of Telmisartan in HumanRui Li, Avijit Ghosh, Tristan S. Maurer, Emi Kimoto and Hugh A. BartonDrug Metabolism and Disposition October 2014, 42 (10) 1646-1655; DOI: https://doi.org/10.1124/dmd.114.058461
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Gilpin, Kyle
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
Goedken, Michael J.
- You have accessIs Nuclear Factor Erythroid 2–Related Factor 2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?Philip R. Rohrer, Swetha Rudraiah, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition October 2014, 42 (10) 1663-1674; DOI: https://doi.org/10.1124/dmd.114.059006
Graf, Tyler N.
- You have accessIdentification of Diet-Derived Constituents as Potent Inhibitors of Intestinal GlucuronidationBrandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition October 2014, 42 (10) 1675-1683; DOI: https://doi.org/10.1124/dmd.114.059451
Gufford, Brandon T.
- You have accessIdentification of Diet-Derived Constituents as Potent Inhibitors of Intestinal GlucuronidationBrandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition October 2014, 42 (10) 1675-1683; DOI: https://doi.org/10.1124/dmd.114.059451
Guimaraes, Cris R. W.
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
H
Harris, Jennifer J.
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Harwood, Matthew D
- You have accessLost in Centrifugation: Accounting for Transporter Protein Losses in Quantitative Targeted Absolute ProteomicsMatthew D Harwood, Matthew R Russell, Sibylle Neuhoff, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition October 2014, 42 (10) 1766-1772; DOI: https://doi.org/10.1124/dmd.114.058446
Hattori, Yoshiki
- You have accessThreonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki and Akira IkariDrug Metabolism and Disposition October 2014, 42 (10) 1708-1718; DOI: https://doi.org/10.1124/dmd.114.059139
Hisaka, Akihiro
- You have accessAssessment of Intestinal Availability (FG) of Substrate Drugs of Cytochrome P450s by Analyzing Changes in Pharmacokinetic Properties Caused by Drug–Drug InteractionsAkihiro Hisaka, Mikiko Nakamura, Ayako Tsukihashi, Saori Koh and Hiroshi SuzukiDrug Metabolism and Disposition October 2014, 42 (10) 1640-1645; DOI: https://doi.org/10.1124/dmd.114.059147
Hollis, Gregory
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Hu, Bingfang
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Huang, Min
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Huang, Yixian
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Hutzler, J. Matthew
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
I
Ikari, Akira
- You have accessThreonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki and Akira IkariDrug Metabolism and Disposition October 2014, 42 (10) 1708-1718; DOI: https://doi.org/10.1124/dmd.114.059139
Ishiguro, Naoki
- You have accessBrain Penetration of WEB 2086 (Apafant) and Dantrolene in Mdr1a (P-Glycoprotein) and Bcrp Knockout RatsHolger Fuchs, Wataru Kishimoto, Dietmar Gansser, Paul Tanswell and Naoki IshiguroDrug Metabolism and Disposition October 2014, 42 (10) 1761-1765; DOI: https://doi.org/10.1124/dmd.114.058545
J
Jiang, Mengxi
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
K
Kawaguchi-Suzuki, Marina
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
Kawanishi, Masanobu
- You have accessMicrobial Metabolites of Omeprazole Activate Murine Aryl Hydrocarbon Receptor In Vitro and In VivoKazuhiro Shiizaki, Masanobu Kawanishi and Takashi YagiDrug Metabolism and Disposition October 2014, 42 (10) 1690-1697; DOI: https://doi.org/10.1124/dmd.114.058966
Kimoto, Emi
- You have accessPhysiologically Based Pharmacokinetic Prediction of Telmisartan in HumanRui Li, Avijit Ghosh, Tristan S. Maurer, Emi Kimoto and Hugh A. BartonDrug Metabolism and Disposition October 2014, 42 (10) 1646-1655; DOI: https://doi.org/10.1124/dmd.114.058461
Kishimoto, Wataru
- You have accessBrain Penetration of WEB 2086 (Apafant) and Dantrolene in Mdr1a (P-Glycoprotein) and Bcrp Knockout RatsHolger Fuchs, Wataru Kishimoto, Dietmar Gansser, Paul Tanswell and Naoki IshiguroDrug Metabolism and Disposition October 2014, 42 (10) 1761-1765; DOI: https://doi.org/10.1124/dmd.114.058545
Koh, Saori
- You have accessAssessment of Intestinal Availability (FG) of Substrate Drugs of Cytochrome P450s by Analyzing Changes in Pharmacokinetic Properties Caused by Drug–Drug InteractionsAkihiro Hisaka, Mikiko Nakamura, Ayako Tsukihashi, Saori Koh and Hiroshi SuzukiDrug Metabolism and Disposition October 2014, 42 (10) 1640-1645; DOI: https://doi.org/10.1124/dmd.114.059147
L
Lazarus, Philip
- You have accessIdentification of Diet-Derived Constituents as Potent Inhibitors of Intestinal GlucuronidationBrandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition October 2014, 42 (10) 1675-1683; DOI: https://doi.org/10.1124/dmd.114.059451
Li, Chunyan
- You have accessCytochrome P450–Mediated Metabolic Activation of Diosbulbin BDongju Lin, Chunyan Li, Ying Peng, Huiyuan Gao and Jiang ZhengDrug Metabolism and Disposition October 2014, 42 (10) 1727-1736; DOI: https://doi.org/10.1124/dmd.114.059261
Li, Rui
- You have accessPhysiologically Based Pharmacokinetic Prediction of Telmisartan in HumanRui Li, Avijit Ghosh, Tristan S. Maurer, Emi Kimoto and Hugh A. BartonDrug Metabolism and Disposition October 2014, 42 (10) 1646-1655; DOI: https://doi.org/10.1124/dmd.114.058461
Li, Song
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Li, Yu
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Lin, Dongju
- You have accessCytochrome P450–Mediated Metabolic Activation of Diosbulbin BDongju Lin, Chunyan Li, Ying Peng, Huiyuan Gao and Jiang ZhengDrug Metabolism and Disposition October 2014, 42 (10) 1727-1736; DOI: https://doi.org/10.1124/dmd.114.059261
Litchfield, John
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Liu, Phillip
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Liu, Suhuan
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Liu, Wei
- You have accessMetabolism of Diosbulbin B In Vitro and In Vivo in Rats: Formation of Reactive Metabolites and Human Enzymes InvolvedBaohua Yang, Wei Liu, Kaixian Chen, Zhengtao Wang and Changhong WangDrug Metabolism and Disposition October 2014, 42 (10) 1737-1750; DOI: https://doi.org/10.1124/dmd.114.058222
M
Manautou, José E.
- You have accessIs Nuclear Factor Erythroid 2–Related Factor 2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?Philip R. Rohrer, Swetha Rudraiah, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition October 2014, 42 (10) 1663-1674; DOI: https://doi.org/10.1124/dmd.114.059006
Markowitz, John S.
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
Maurer, Tristan S.
- You have accessPhysiologically Based Pharmacokinetic Prediction of Telmisartan in HumanRui Li, Avijit Ghosh, Tristan S. Maurer, Emi Kimoto and Hugh A. BartonDrug Metabolism and Disposition October 2014, 42 (10) 1646-1655; DOI: https://doi.org/10.1124/dmd.114.058461
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Mescoli, Claudia
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
N
Nakamura, Mikiko
- You have accessAssessment of Intestinal Availability (FG) of Substrate Drugs of Cytochrome P450s by Analyzing Changes in Pharmacokinetic Properties Caused by Drug–Drug InteractionsAkihiro Hisaka, Mikiko Nakamura, Ayako Tsukihashi, Saori Koh and Hiroshi SuzukiDrug Metabolism and Disposition October 2014, 42 (10) 1640-1645; DOI: https://doi.org/10.1124/dmd.114.059147
Nanovskaya, Tatiana N.
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
Neuhoff, Sibylle
- You have accessLost in Centrifugation: Accounting for Transporter Protein Losses in Quantitative Targeted Absolute ProteomicsMatthew D Harwood, Matthew R Russell, Sibylle Neuhoff, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition October 2014, 42 (10) 1766-1772; DOI: https://doi.org/10.1124/dmd.114.058446
Noguchi, Yuji
- You have accessThreonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki and Akira IkariDrug Metabolism and Disposition October 2014, 42 (10) 1708-1718; DOI: https://doi.org/10.1124/dmd.114.059139
O
Obach, R. Scott
- You have accessBiosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism StudiesGregory S. Walker, Jonathan N. Bauman, Tim F. Ryder, Evan B. Smith, Douglas K. Spracklin and R. Scott ObachDrug Metabolism and Disposition October 2014, 42 (10) 1627-1639; DOI: https://doi.org/10.1124/dmd.114.059204
Oberlies, Nicholas H.
- You have accessIdentification of Diet-Derived Constituents as Potent Inhibitors of Intestinal GlucuronidationBrandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition October 2014, 42 (10) 1675-1683; DOI: https://doi.org/10.1124/dmd.114.059451
Ohtsuki, Sumio
- You have accessPharmacoproteomics-Based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-Kindled Epilepsy, Spontaneous Epilepsy, and Phenytoin Treatment ModelsYasuo Uchida, Sumio Ohtsuki and Tetsuya TerasakiDrug Metabolism and Disposition October 2014, 42 (10) 1719-1726; DOI: https://doi.org/10.1124/dmd.114.059055
Ou, Zhimin
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
P
Paine, Mary F.
- You have accessIdentification of Diet-Derived Constituents as Potent Inhibitors of Intestinal GlucuronidationBrandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition October 2014, 42 (10) 1675-1683; DOI: https://doi.org/10.1124/dmd.114.059451
Palatini, Pietro
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Paliuri, Giovanna
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Peng, Ying
- You have accessCytochrome P450–Mediated Metabolic Activation of Diosbulbin BDongju Lin, Chunyan Li, Ying Peng, Huiyuan Gao and Jiang ZhengDrug Metabolism and Disposition October 2014, 42 (10) 1727-1736; DOI: https://doi.org/10.1124/dmd.114.059261
R
Ren, Songrong
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Rock, Brooke M.
- You have accessCharacterization of the Active Site Properties of CYP4F12John Eksterowicz, Dan A. Rock, Brooke M. Rock, Larry C. Wienkers and Robert S. FotiDrug Metabolism and Disposition October 2014, 42 (10) 1698-1707; DOI: https://doi.org/10.1124/dmd.114.059626
Rock, Dan A.
- You have accessCharacterization of the Active Site Properties of CYP4F12John Eksterowicz, Dan A. Rock, Brooke M. Rock, Larry C. Wienkers and Robert S. FotiDrug Metabolism and Disposition October 2014, 42 (10) 1698-1707; DOI: https://doi.org/10.1124/dmd.114.059626
Rohrer, Philip R.
- You have accessIs Nuclear Factor Erythroid 2–Related Factor 2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?Philip R. Rohrer, Swetha Rudraiah, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition October 2014, 42 (10) 1663-1674; DOI: https://doi.org/10.1124/dmd.114.059006
Rostami-Hodjegan, Amin
- You have accessLost in Centrifugation: Accounting for Transporter Protein Losses in Quantitative Targeted Absolute ProteomicsMatthew D Harwood, Matthew R Russell, Sibylle Neuhoff, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition October 2014, 42 (10) 1766-1772; DOI: https://doi.org/10.1124/dmd.114.058446
Rotter, Charles
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Rudraiah, Swetha
- You have accessIs Nuclear Factor Erythroid 2–Related Factor 2 Responsible for Sex Differences in Susceptibility to Acetaminophen-Induced Hepatotoxicity in Mice?Philip R. Rohrer, Swetha Rudraiah, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition October 2014, 42 (10) 1663-1674; DOI: https://doi.org/10.1124/dmd.114.059006
Rupar, Mark
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Russell, Matthew R
- You have accessLost in Centrifugation: Accounting for Transporter Protein Losses in Quantitative Targeted Absolute ProteomicsMatthew D Harwood, Matthew R Russell, Sibylle Neuhoff, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition October 2014, 42 (10) 1766-1772; DOI: https://doi.org/10.1124/dmd.114.058446
Ryder, Tim F.
- You have accessBiosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism StudiesGregory S. Walker, Jonathan N. Bauman, Tim F. Ryder, Evan B. Smith, Douglas K. Spracklin and R. Scott ObachDrug Metabolism and Disposition October 2014, 42 (10) 1627-1639; DOI: https://doi.org/10.1124/dmd.114.059204
Rytting, Erik
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
S
Scialis, Renato
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Scott, Dennis O.
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Sfriso, Maria Martina
- You have accessDifferential Effect of Liver Cirrhosis on the Pregnane X Receptor–Mediated Induction of CYP3A1 and 3A2 in the RatSara De Martin, Daniela Gabbia, Giovanna Albertin, Maria Martina Sfriso, Claudia Mescoli, Laura Albertoni, Giovanna Paliuri, Sergio Bova and Pietro PalatiniDrug Metabolism and Disposition October 2014, 42 (10) 1617-1626; DOI: https://doi.org/10.1124/dmd.114.058511
Shiizaki, Kazuhiro
- You have accessMicrobial Metabolites of Omeprazole Activate Murine Aryl Hydrocarbon Receptor In Vitro and In VivoKazuhiro Shiizaki, Masanobu Kawanishi and Takashi YagiDrug Metabolism and Disposition October 2014, 42 (10) 1690-1697; DOI: https://doi.org/10.1124/dmd.114.058966
Smith, Evan B.
- You have accessBiosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism StudiesGregory S. Walker, Jonathan N. Bauman, Tim F. Ryder, Evan B. Smith, Douglas K. Spracklin and R. Scott ObachDrug Metabolism and Disposition October 2014, 42 (10) 1627-1639; DOI: https://doi.org/10.1124/dmd.114.059204
Spracklin, Douglas K.
- You have accessBiosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism StudiesGregory S. Walker, Jonathan N. Bauman, Tim F. Ryder, Evan B. Smith, Douglas K. Spracklin and R. Scott ObachDrug Metabolism and Disposition October 2014, 42 (10) 1627-1639; DOI: https://doi.org/10.1124/dmd.114.059204
Sugatani, Junko
- You have accessThreonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki and Akira IkariDrug Metabolism and Disposition October 2014, 42 (10) 1708-1718; DOI: https://doi.org/10.1124/dmd.114.059139
Suzuki, Hiroshi
- You have accessAssessment of Intestinal Availability (FG) of Substrate Drugs of Cytochrome P450s by Analyzing Changes in Pharmacokinetic Properties Caused by Drug–Drug InteractionsAkihiro Hisaka, Mikiko Nakamura, Ayako Tsukihashi, Saori Koh and Hiroshi SuzukiDrug Metabolism and Disposition October 2014, 42 (10) 1640-1645; DOI: https://doi.org/10.1124/dmd.114.059147
T
Tanswell, Paul
- You have accessBrain Penetration of WEB 2086 (Apafant) and Dantrolene in Mdr1a (P-Glycoprotein) and Bcrp Knockout RatsHolger Fuchs, Wataru Kishimoto, Dietmar Gansser, Paul Tanswell and Naoki IshiguroDrug Metabolism and Disposition October 2014, 42 (10) 1761-1765; DOI: https://doi.org/10.1124/dmd.114.058545
Terasaki, Tetsuya
- You have accessPharmacoproteomics-Based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-Kindled Epilepsy, Spontaneous Epilepsy, and Phenytoin Treatment ModelsYasuo Uchida, Sumio Ohtsuki and Tetsuya TerasakiDrug Metabolism and Disposition October 2014, 42 (10) 1719-1726; DOI: https://doi.org/10.1124/dmd.114.059055
Tsukihashi, Ayako
- You have accessAssessment of Intestinal Availability (FG) of Substrate Drugs of Cytochrome P450s by Analyzing Changes in Pharmacokinetic Properties Caused by Drug–Drug InteractionsAkihiro Hisaka, Mikiko Nakamura, Ayako Tsukihashi, Saori Koh and Hiroshi SuzukiDrug Metabolism and Disposition October 2014, 42 (10) 1640-1645; DOI: https://doi.org/10.1124/dmd.114.059147
Tu, Meihua
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
U
Uchida, Yasuo
- You have accessPharmacoproteomics-Based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-Kindled Epilepsy, Spontaneous Epilepsy, and Phenytoin Treatment ModelsYasuo Uchida, Sumio Ohtsuki and Tetsuya TerasakiDrug Metabolism and Disposition October 2014, 42 (10) 1719-1726; DOI: https://doi.org/10.1124/dmd.114.059055
V
Varma, Manthema V.
- You have accessToward a Unified Model of Passive Drug Permeation II: The Physiochemical Determinants of Unbound Tissue Distribution with Applications to the Design of Hepatoselective Glucokinase ActivatorsAvijit Ghosh, Tristan S. Maurer, John Litchfield, Manthema V. Varma, Charles Rotter, Renato Scialis, Bo Feng, Meihua Tu, Cris R. W. Guimaraes and Dennis O. ScottDrug Metabolism and Disposition October 2014, 42 (10) 1599-1610; DOI: https://doi.org/10.1124/dmd.114.058032
Vernikovskaya, Daria I.
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
W
Walker, Gregory S.
- You have accessBiosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism StudiesGregory S. Walker, Jonathan N. Bauman, Tim F. Ryder, Evan B. Smith, Douglas K. Spracklin and R. Scott ObachDrug Metabolism and Disposition October 2014, 42 (10) 1627-1639; DOI: https://doi.org/10.1124/dmd.114.059204
Wang, Changhong
- You have accessMetabolism of Diosbulbin B In Vitro and In Vivo in Rats: Formation of Reactive Metabolites and Human Enzymes InvolvedBaohua Yang, Wei Liu, Kaixian Chen, Zhengtao Wang and Changhong WangDrug Metabolism and Disposition October 2014, 42 (10) 1737-1750; DOI: https://doi.org/10.1124/dmd.114.058222
Wang, Xiaoming
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
Wang, Zhengtao
- You have accessMetabolism of Diosbulbin B In Vitro and In Vivo in Rats: Formation of Reactive Metabolites and Human Enzymes InvolvedBaohua Yang, Wei Liu, Kaixian Chen, Zhengtao Wang and Changhong WangDrug Metabolism and Disposition October 2014, 42 (10) 1737-1750; DOI: https://doi.org/10.1124/dmd.114.058222
Warhurst, Geoffrey
- You have accessLost in Centrifugation: Accounting for Transporter Protein Losses in Quantitative Targeted Absolute ProteomicsMatthew D Harwood, Matthew R Russell, Sibylle Neuhoff, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition October 2014, 42 (10) 1766-1772; DOI: https://doi.org/10.1124/dmd.114.058446
Wienkers, Larry C.
- You have accessCharacterization of the Active Site Properties of CYP4F12John Eksterowicz, Dan A. Rock, Brooke M. Rock, Larry C. Wienkers and Robert S. FotiDrug Metabolism and Disposition October 2014, 42 (10) 1698-1707; DOI: https://doi.org/10.1124/dmd.114.059626
Wong, Diane
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
Wynn, Richard
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
X
Xie, Wen
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Xu, Meishu
- You have accessTranscriptional Regulation of Human Hydroxysteroid Sulfotransferase SULT2A1 by LXRαZhimin Ou, Mengxi Jiang, Bingfang Hu, Yixian Huang, Meishu Xu, Songrong Ren, Song Li, Suhuan Liu, Wen Xie and Min HuangDrug Metabolism and Disposition October 2014, 42 (10) 1684-1689; DOI: https://doi.org/10.1124/dmd.114.058479
Y
Yagi, Takashi
- You have accessMicrobial Metabolites of Omeprazole Activate Murine Aryl Hydrocarbon Receptor In Vitro and In VivoKazuhiro Shiizaki, Masanobu Kawanishi and Takashi YagiDrug Metabolism and Disposition October 2014, 42 (10) 1690-1697; DOI: https://doi.org/10.1124/dmd.114.058966
Yamaguchi, Masahiko
- You have accessThreonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki and Akira IkariDrug Metabolism and Disposition October 2014, 42 (10) 1708-1718; DOI: https://doi.org/10.1124/dmd.114.059139
Yamazaki, Yasuhiro
- You have accessThreonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki and Akira IkariDrug Metabolism and Disposition October 2014, 42 (10) 1708-1718; DOI: https://doi.org/10.1124/dmd.114.059139
Yang, Baohua
- You have accessMetabolism of Diosbulbin B In Vitro and In Vivo in Rats: Formation of Reactive Metabolites and Human Enzymes InvolvedBaohua Yang, Wei Liu, Kaixian Chen, Zhengtao Wang and Changhong WangDrug Metabolism and Disposition October 2014, 42 (10) 1737-1750; DOI: https://doi.org/10.1124/dmd.114.058222
Yang, Young-Sun
- You have accessCynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle GilpinDrug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
Yeleswaram, Swamy
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Z
Zhan, Ying
- You have accessMetabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)Erik Rytting, Xiaoming Wang, Daria I. Vernikovskaya, Ying Zhan, Cassondra Bauer, Susan M. Abdel-Rahman, Mahmoud S. Ahmed and Tatiana N. NanovskayaDrug Metabolism and Disposition October 2014, 42 (10) 1773-1779; DOI: https://doi.org/10.1124/dmd.114.058255
Zhang, Qiang
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Zhang, Yan
- You have accessThe Janus Kinase 2 Inhibitor Fedratinib Inhibits Thiamine Uptake: A Putative Mechanism for the Onset of Wernicke’s EncephalopathyQiang Zhang, Yan Zhang, Sharon Diamond, Jason Boer, Jennifer J. Harris, Yu Li, Mark Rupar, Elham Behshad, Christine Gardiner, Paul Collier, Phillip Liu, Timothy Burn, Richard Wynn, Gregory Hollis and Swamy YeleswaramDrug Metabolism and Disposition October 2014, 42 (10) 1656-1662; DOI: https://doi.org/10.1124/dmd.114.058883
Zheng, Jiang
- You have accessCytochrome P450–Mediated Metabolic Activation of Diosbulbin BDongju Lin, Chunyan Li, Ying Peng, Huiyuan Gao and Jiang ZhengDrug Metabolism and Disposition October 2014, 42 (10) 1727-1736; DOI: https://doi.org/10.1124/dmd.114.059261
Zhu, Hao-Jie
- You have accessThe Effects of Milk Thistle (Silybum marianum) on Human Cytochrome P450 ActivityMarina Kawaguchi-Suzuki, Reginald F. Frye, Hao-Jie Zhu, Bryan J. Brinda, Kenneth D. Chavin, Hilary J. Bernstein and John S. MarkowitzDrug Metabolism and Disposition October 2014, 42 (10) 1611-1616; DOI: https://doi.org/10.1124/dmd.114.057232
In this issue
Advertisement