Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)

Systems Modeling and Simulation (A.G., T.S.M.), Cardiovascular and Metabolic Disease Research Unit (J.L., D.O.S.), Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Cambridge, Massachusetts; Enzymology and Transporters, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer, Groton, Connecticut (B.F., M.V.V., C.R., R.S.); and World Wide Medicinal Chemistry, Cambridge, Massachusetts (M.T., C.R.W.G.)