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Research ArticleArticle

Cynomolgus Monkey as a Surrogate for Human Aldehyde Oxidase Metabolism of the EGFR Inhibitor BIBX1382

J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle Gilpin
Drug Metabolism and Disposition October 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030

Article Information

vol. 42 no. 10 1751-1760
DOI 
https://doi.org/10.1124/dmd.114.059030
PubMed 
25035284
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 13, 2014
  • Accepted July 17, 2014
  • Published online September 5, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. J. Matthew Hutzler,
  2. Matthew A. Cerny,
  3. Young-Sun Yang,
  4. Constance Asher,
  5. Diane Wong,
  6. Kosea Frederick, and
  7. Kyle Gilpin
  1. Boehringer-Ingelheim Pharmaceuticals Inc., Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut
  1. Address correspondence to:
    Dr. J. Matthew Hutzler, Quintiles, Bioanalytical and ADME Laboratories, 5225 Exploration Drive, Indianapolis, IN 46241. E-mail: matt.hutzler{at}quintiles.com
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Research ArticleArticle

BIBX1382 Metabolism in Human and Cynomolgus Monkey

J. Matthew Hutzler, Matthew A. Cerny, Young-Sun Yang, Constance Asher, Diane Wong, Kosea Frederick and Kyle Gilpin
Drug Metabolism and Disposition October 1, 2014, 42 (10) 1751-1760; DOI: https://doi.org/10.1124/dmd.114.059030
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