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Index by author

November 01, 2014; Volume 42,Issue 11

A

  1. Abbott, Frank S.

    1. Evaluation of In Situ Generated Valproyl 1-O-β-Acyl Glucuronide in Valproic Acid Toxicity in Sandwich-Cultured Rat Hepatocytes
      Jayakumar Surendradoss, Thomas K. H. Chang and Frank S. Abbott
      Drug Metabolism and Disposition November 2014, 42 (11) 1834-1842; DOI: https://doi.org/10.1124/dmd.114.059352

  2. Abdalla, Nagi

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  3. Abuqayyas, Lubna

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

  4. Ahluwalia, Jasjit S.

    1. Gene Variants in CYP2C19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes
      Andy Z. X. Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S. Ahluwalia, Neal L. Benowitz and Rachel F. Tyndale
      Drug Metabolism and Disposition November 2014, 42 (11) 1971-1977; DOI: https://doi.org/10.1124/dmd.114.060285

  5. Akiyama, Yutaka

    1. In Silico Prediction of Major Drug Clearance Pathways by Support Vector Machines with Feature-Selected Descriptors
      Kouta Toshimoto, Naomi Wakayama, Makiko Kusama, Kazuya Maeda, Yuichi Sugiyama and Yutaka Akiyama
      Drug Metabolism and Disposition November 2014, 42 (11) 1811-1819; DOI: https://doi.org/10.1124/dmd.114.057893

  6. Amin, Neeta B.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  7. An, Bo

    1. Toward Sensitive and Accurate Analysis of Antibody Biotherapeutics by Liquid Chromatography Coupled with Mass Spectrometry
      Bo An, Ming Zhang and Jun Qu
      Drug Metabolism and Disposition November 2014, 42 (11) 1858-1866; DOI: https://doi.org/10.1124/dmd.114.058917

  8. Atkinson, Karen

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

B

  1. Balthasar, Joseph P.

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

  2. Benowitz, Neal L.

    1. Gene Variants in CYP2C19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes
      Andy Z. X. Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S. Ahluwalia, Neal L. Benowitz and Rachel F. Tyndale
      Drug Metabolism and Disposition November 2014, 42 (11) 1971-1977; DOI: https://doi.org/10.1124/dmd.114.060285

  3. Brouwer, Kim L. R.

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

  4. Buchwald, Peter

    1. Activity-Limiting Role of Molecular Size: Size-Dependency of Maximum Activity for P450 Inhibition as Revealed by qHTS Data
      Peter Buchwald
      Drug Metabolism and Disposition November 2014, 42 (11) 1785-1790; DOI: https://doi.org/10.1124/dmd.114.059717

  5. Bumpus, Namandjé N.

    1. CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition November 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194

C

  1. Cai, Jianping

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  2. Chan, Ting

    1. Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors
      Rosie A. Johnston, Tristan Rawling, Ting Chan, Fanfan Zhou and Michael Murray
      Drug Metabolism and Disposition November 2014, 42 (11) 1851-1857; DOI: https://doi.org/10.1124/dmd.114.059097

  3. Chan, Tom S.

    1. Altered CYP2C9 Activity Following Modulation of CYP3A4 Levels in Human Hepatocytes: an Example of Protein-Protein Interactions
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan and Timothy S. Tracy
      Drug Metabolism and Disposition November 2014, 42 (11) 1940-1946; DOI: https://doi.org/10.1124/dmd.114.057901

  4. Chang, Thomas K. H.

    1. Evaluation of In Situ Generated Valproyl 1-O-β-Acyl Glucuronide in Valproic Acid Toxicity in Sandwich-Cultured Rat Hepatocytes
      Jayakumar Surendradoss, Thomas K. H. Chang and Frank S. Abbott
      Drug Metabolism and Disposition November 2014, 42 (11) 1834-1842; DOI: https://doi.org/10.1124/dmd.114.059352

  5. Chen, Mengchun

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  6. Cheng, Xingguo

    1. Adaptive Hepatic and Intestinal Alterations in Mice after Deletion of NADPH-Cytochrome P450 Oxidoreductase (Cpr) in Hepatocytes
      Xingguo Cheng, Jun Gu and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2014, 42 (11) 1826-1833; DOI: https://doi.org/10.1124/dmd.114.060053

  7. Chiba, Masato

    1. Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans
      Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao and Tamihide Matsunaga
      Drug Metabolism and Disposition November 2014, 42 (11) 1947-1954; DOI: https://doi.org/10.1124/dmd.114.059493

  8. Choi, Chang-Soo

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  9. Collier, Abby C.

    1. UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst
      Abby C. Collier, Yasuhiro Yamauchi, Brittany L.M. Sato, Luc R.A. Rougée and Monika A. Ward
      Drug Metabolism and Disposition November 2014, 42 (11) 1921-1925; DOI: https://doi.org/10.1124/dmd.114.059766

  10. Conner, Kip P.

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

  11. Cox, Lisa Sanderson

    1. Gene Variants in CYP2C19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes
      Andy Z. X. Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S. Ahluwalia, Neal L. Benowitz and Rachel F. Tyndale
      Drug Metabolism and Disposition November 2014, 42 (11) 1971-1977; DOI: https://doi.org/10.1124/dmd.114.060285

D

  1. Dai, Dapeng

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  2. Dalvie, Deepak K.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  3. Datta-Mannan, Amita

    1. Application of FcRn Binding Assays to Guide mAb Development
      Amita Datta-Mannan and Victor J. Wroblewski
      Drug Metabolism and Disposition November 2014, 42 (11) 1867-1872; DOI: https://doi.org/10.1124/dmd.114.059089

  4. Denney, William S.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  5. Di, Li

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  6. Duffel, Michael W.

    1. Endoxifen and Other Metabolites of Tamoxifen Inhibit Human Hydroxysteroid Sulfotransferase 2A1 (hSULT2A1)
      Edwin J. Squirewell, Xiaoyan Qin and Michael W. Duffel
      Drug Metabolism and Disposition November 2014, 42 (11) 1843-1850; DOI: https://doi.org/10.1124/dmd.114.059709

E

  1. Eng, Heather

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

F

  1. Farasyn, Taleah

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

  2. Ford, Kevin A.

    1. Mechanistic Studies of the Cationic Binding Pocket of CYP2C9 In Vitro and In Silico: Metabolism of Nonionizable Analogs of Tienilic Acid
      Suzanne Tay, Hoa Le, Kevin A. Ford, Sid D. Nelson, S. Cyrus Khojasteh and Peter M. Rademacher
      Drug Metabolism and Disposition November 2014, 42 (11) 1955-1963; DOI: https://doi.org/10.1124/dmd.114.059022

  3. Fuchs, Edward J.

    1. CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition November 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194

G

  1. Goosen, Theunis C.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  2. Gu, Jun

    1. Adaptive Hepatic and Intestinal Alterations in Mice after Deletion of NADPH-Cytochrome P450 Oxidoreductase (Cpr) in Hepatocytes
      Xingguo Cheng, Jun Gu and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2014, 42 (11) 1826-1833; DOI: https://doi.org/10.1124/dmd.114.060053

H

  1. Hall, Michael P.

    1. Biotransformation and In Vivo Stability of Protein Biotherapeutics: Impact on Candidate Selection and Pharmacokinetic Profiling
      Michael P. Hall
      Drug Metabolism and Disposition November 2014, 42 (11) 1873-1880; DOI: https://doi.org/10.1124/dmd.114.058347

  2. Han, Tae H.

    1. Absorption, Distribution, Metabolism, and Excretion Considerations for the Development of Antibody-Drug Conjugates
      Tae H. Han and Baiteng Zhao
      Drug Metabolism and Disposition November 2014, 42 (11) 1914-1920; DOI: https://doi.org/10.1124/dmd.114.058586

  3. Harada, Naomoto

    1. Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans
      Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao and Tamihide Matsunaga
      Drug Metabolism and Disposition November 2014, 42 (11) 1947-1954; DOI: https://doi.org/10.1124/dmd.114.059493

  4. Hendrix, Craig W.

    1. CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition November 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194

  5. Higgins, J. William

    1. Clinical CYP3A Inhibitor Alternatives to Ketoconazole, Clarithromycin and Itraconazole, Are Not Transported into the Liver by Hepatic Organic Anion Transporting Polypeptides and Organic Cation Transporter 1
      J. William Higgins, Alice B. Ke and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition November 2014, 42 (11) 1780-1784; DOI: https://doi.org/10.1124/dmd.114.058784

  6. Hu, Guoxin

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  7. Huang, Min

    1. Rapid Production of Novel Pre-MicroRNA Agent hsa-mir-27b in Escherichia coli Using Recombinant RNA Technology for Functional Studies in Mammalian Cells
      Mei-Mei Li, Wei-Peng Wang, Wen-Juan Wu, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition November 2014, 42 (11) 1791-1795; DOI: https://doi.org/10.1124/dmd.114.060145

I

  1. Iwao, Takahiro

    1. Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans
      Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao and Tamihide Matsunaga
      Drug Metabolism and Disposition November 2014, 42 (11) 1947-1954; DOI: https://doi.org/10.1124/dmd.114.059493

J

  1. Jacobsen, Björn

    1. Subcutaneous Absorption of Biotherapeutics: Knowns and Unknowns
      Wolfgang F. Richter and Björn Jacobsen
      Drug Metabolism and Disposition November 2014, 42 (11) 1881-1889; DOI: https://doi.org/10.1124/dmd.114.059238

  2. Jeong, Eun Sook

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  3. Jin, Hui

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  4. Johnston, Rosie A.

    1. Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors
      Rosie A. Johnston, Tristan Rawling, Ting Chan, Fanfan Zhou and Michael Murray
      Drug Metabolism and Disposition November 2014, 42 (11) 1851-1857; DOI: https://doi.org/10.1124/dmd.114.059097

K

  1. Kagan, Leonid

    1. Pharmacokinetic Modeling of the Subcutaneous Absorption of Therapeutic Proteins
      Leonid Kagan
      Drug Metabolism and Disposition November 2014, 42 (11) 1890-1905; DOI: https://doi.org/10.1124/dmd.114.059121

  2. Kalgutkar, Amit S.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  3. Ke, Alice B.

    1. Clinical CYP3A Inhibitor Alternatives to Ketoconazole, Clarithromycin and Itraconazole, Are Not Transported into the Liver by Hepatic Organic Anion Transporting Polypeptides and Organic Cation Transporter 1
      J. William Higgins, Alice B. Ke and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition November 2014, 42 (11) 1780-1784; DOI: https://doi.org/10.1124/dmd.114.058784

  4. Khojasteh, S. Cyrus

    1. Mechanistic Studies of the Cationic Binding Pocket of CYP2C9 In Vitro and In Silico: Metabolism of Nonionizable Analogs of Tienilic Acid
      Suzanne Tay, Hoa Le, Kevin A. Ford, Sid D. Nelson, S. Cyrus Khojasteh and Peter M. Rademacher
      Drug Metabolism and Disposition November 2014, 42 (11) 1955-1963; DOI: https://doi.org/10.1124/dmd.114.059022

  5. Kim, Dong-Hyun

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  6. Kim, Hyo-Ji

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  7. Klaassen, Curtis D.

    1. Adaptive Hepatic and Intestinal Alterations in Mice after Deletion of NADPH-Cytochrome P450 Oxidoreductase (Cpr) in Hepatocytes
      Xingguo Cheng, Jun Gu and Curtis D. Klaassen
      Drug Metabolism and Disposition November 2014, 42 (11) 1826-1833; DOI: https://doi.org/10.1124/dmd.114.060053

  8. Köck, Kathleen

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

  9. Kusama, Makiko

    1. In Silico Prediction of Major Drug Clearance Pathways by Support Vector Machines with Feature-Selected Descriptors
      Kouta Toshimoto, Naomi Wakayama, Makiko Kusama, Kazuya Maeda, Yuichi Sugiyama and Yutaka Akiyama
      Drug Metabolism and Disposition November 2014, 42 (11) 1811-1819; DOI: https://doi.org/10.1124/dmd.114.057893

  10. Kuze, Jiro

    1. Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans
      Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao and Tamihide Matsunaga
      Drug Metabolism and Disposition November 2014, 42 (11) 1947-1954; DOI: https://doi.org/10.1124/dmd.114.059493

  11. Kwon, Gayle K.

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

L

  1. Le, Hoa

    1. Mechanistic Studies of the Cationic Binding Pocket of CYP2C9 In Vitro and In Silico: Metabolism of Nonionizable Analogs of Tienilic Acid
      Suzanne Tay, Hoa Le, Kevin A. Ford, Sid D. Nelson, S. Cyrus Khojasteh and Peter M. Rademacher
      Drug Metabolism and Disposition November 2014, 42 (11) 1955-1963; DOI: https://doi.org/10.1124/dmd.114.059022

  2. Lee, Esther

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  3. Li, Mei-Mei

    1. Rapid Production of Novel Pre-MicroRNA Agent hsa-mir-27b in Escherichia coli Using Recombinant RNA Technology for Functional Studies in Mammalian Cells
      Mei-Mei Li, Wei-Peng Wang, Wen-Juan Wu, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition November 2014, 42 (11) 1791-1795; DOI: https://doi.org/10.1124/dmd.114.060145

  4. Litchfield, John

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  5. Lu, Yanhui

    1. CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition November 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194

M

  1. Maeda, Kazuya

    1. In Silico Prediction of Major Drug Clearance Pathways by Support Vector Machines with Feature-Selected Descriptors
      Kouta Toshimoto, Naomi Wakayama, Makiko Kusama, Kazuya Maeda, Yuichi Sugiyama and Yutaka Akiyama
      Drug Metabolism and Disposition November 2014, 42 (11) 1811-1819; DOI: https://doi.org/10.1124/dmd.114.057893

  2. Matsunaga, Tamihide

    1. Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans
      Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao and Tamihide Matsunaga
      Drug Metabolism and Disposition November 2014, 42 (11) 1947-1954; DOI: https://doi.org/10.1124/dmd.114.059493

  3. Meng, Xiaojie

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

  4. Murray, Michael

    1. Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors
      Rosie A. Johnston, Tristan Rawling, Ting Chan, Fanfan Zhou and Michael Murray
      Drug Metabolism and Disposition November 2014, 42 (11) 1851-1857; DOI: https://doi.org/10.1124/dmd.114.059097

N

  1. Nelson, Sid D.

    1. Mechanistic Studies of the Cationic Binding Pocket of CYP2C9 In Vitro and In Silico: Metabolism of Nonionizable Analogs of Tienilic Acid
      Suzanne Tay, Hoa Le, Kevin A. Ford, Sid D. Nelson, S. Cyrus Khojasteh and Peter M. Rademacher
      Drug Metabolism and Disposition November 2014, 42 (11) 1955-1963; DOI: https://doi.org/10.1124/dmd.114.059022

P

  1. Pahwa, Sonia

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

  2. Pan, Peipei

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  3. Pettersen, John C.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  4. Pfefferkorn, Jeffrey A.

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  5. Powell, John

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

Q

  1. Qin, Xiaoyan

    1. Endoxifen and Other Metabolites of Tamoxifen Inhibit Human Hydroxysteroid Sulfotransferase 2A1 (hSULT2A1)
      Edwin J. Squirewell, Xiaoyan Qin and Michael W. Duffel
      Drug Metabolism and Disposition November 2014, 42 (11) 1843-1850; DOI: https://doi.org/10.1124/dmd.114.059709

  2. Qu, Jun

    1. Toward Sensitive and Accurate Analysis of Antibody Biotherapeutics by Liquid Chromatography Coupled with Mass Spectrometry
      Bo An, Ming Zhang and Jun Qu
      Drug Metabolism and Disposition November 2014, 42 (11) 1858-1866; DOI: https://doi.org/10.1124/dmd.114.058917

R

  1. Rademacher, Peter M.

    1. Mechanistic Studies of the Cationic Binding Pocket of CYP2C9 In Vitro and In Silico: Metabolism of Nonionizable Analogs of Tienilic Acid
      Suzanne Tay, Hoa Le, Kevin A. Ford, Sid D. Nelson, S. Cyrus Khojasteh and Peter M. Rademacher
      Drug Metabolism and Disposition November 2014, 42 (11) 1955-1963; DOI: https://doi.org/10.1124/dmd.114.059022

  2. Ramsden, Diane

    1. Altered CYP2C9 Activity Following Modulation of CYP3A4 Levels in Human Hepatocytes: an Example of Protein-Protein Interactions
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan and Timothy S. Tracy
      Drug Metabolism and Disposition November 2014, 42 (11) 1940-1946; DOI: https://doi.org/10.1124/dmd.114.057901

  3. Rawling, Tristan

    1. Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors
      Rosie A. Johnston, Tristan Rawling, Ting Chan, Fanfan Zhou and Michael Murray
      Drug Metabolism and Disposition November 2014, 42 (11) 1851-1857; DOI: https://doi.org/10.1124/dmd.114.059097

  4. Richter, Wolfgang F.

    1. Subcutaneous Absorption of Biotherapeutics: Knowns and Unknowns
      Wolfgang F. Richter and Björn Jacobsen
      Drug Metabolism and Disposition November 2014, 42 (11) 1881-1889; DOI: https://doi.org/10.1124/dmd.114.059238

  5. Rock, Brooke M.

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

  6. Rock, Dan A.

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

  7. Rougée, Luc R.A.

    1. UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst
      Abby C. Collier, Yasuhiro Yamauchi, Brittany L.M. Sato, Luc R.A. Rougée and Monika A. Ward
      Drug Metabolism and Disposition November 2014, 42 (11) 1921-1925; DOI: https://doi.org/10.1124/dmd.114.059766

S

  1. Sato, Brittany L.M.

    1. UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst
      Abby C. Collier, Yasuhiro Yamauchi, Brittany L.M. Sato, Luc R.A. Rougée and Monika A. Ward
      Drug Metabolism and Disposition November 2014, 42 (11) 1921-1925; DOI: https://doi.org/10.1124/dmd.114.059766

  2. Seo, Kyung-Ah

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  3. Sharma, Raman

    1. Metabolites in Safety Testing Assessment in Early Clinical Development: A Case Study with a Glucokinase Activator
      Raman Sharma, John Litchfield, Karen Atkinson, Heather Eng, Neeta B. Amin, William S. Denney, John C. Pettersen, Theunis C. Goosen, Li Di, Esther Lee, Jeffrey A. Pfefferkorn, Deepak K. Dalvie and Amit S. Kalgutkar
      Drug Metabolism and Disposition November 2014, 42 (11) 1926-1939; DOI: https://doi.org/10.1124/dmd.114.060087

  4. Shin, Jae-Gook

    1. In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry
      Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
      Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

  5. Squirewell, Edwin J.

    1. Endoxifen and Other Metabolites of Tamoxifen Inhibit Human Hydroxysteroid Sulfotransferase 2A1 (hSULT2A1)
      Edwin J. Squirewell, Xiaoyan Qin and Michael W. Duffel
      Drug Metabolism and Disposition November 2014, 42 (11) 1843-1850; DOI: https://doi.org/10.1124/dmd.114.059709

  6. Sugiyama, Yuichi

    1. In Silico Prediction of Major Drug Clearance Pathways by Support Vector Machines with Feature-Selected Descriptors
      Kouta Toshimoto, Naomi Wakayama, Makiko Kusama, Kazuya Maeda, Yuichi Sugiyama and Yutaka Akiyama
      Drug Metabolism and Disposition November 2014, 42 (11) 1811-1819; DOI: https://doi.org/10.1124/dmd.114.057893

  7. Surendradoss, Jayakumar

    1. Evaluation of In Situ Generated Valproyl 1-O-β-Acyl Glucuronide in Valproic Acid Toxicity in Sandwich-Cultured Rat Hepatocytes
      Jayakumar Surendradoss, Thomas K. H. Chang and Frank S. Abbott
      Drug Metabolism and Disposition November 2014, 42 (11) 1834-1842; DOI: https://doi.org/10.1124/dmd.114.059352

T

  1. Takenaka, Toru

    1. Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans
      Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao and Tamihide Matsunaga
      Drug Metabolism and Disposition November 2014, 42 (11) 1947-1954; DOI: https://doi.org/10.1124/dmd.114.059493

  2. Tay, Suzanne

    1. Mechanistic Studies of the Cationic Binding Pocket of CYP2C9 In Vitro and In Silico: Metabolism of Nonionizable Analogs of Tienilic Acid
      Suzanne Tay, Hoa Le, Kevin A. Ford, Sid D. Nelson, S. Cyrus Khojasteh and Peter M. Rademacher
      Drug Metabolism and Disposition November 2014, 42 (11) 1955-1963; DOI: https://doi.org/10.1124/dmd.114.059022

  3. Toshimoto, Kouta

    1. In Silico Prediction of Major Drug Clearance Pathways by Support Vector Machines with Feature-Selected Descriptors
      Kouta Toshimoto, Naomi Wakayama, Makiko Kusama, Kazuya Maeda, Yuichi Sugiyama and Yutaka Akiyama
      Drug Metabolism and Disposition November 2014, 42 (11) 1811-1819; DOI: https://doi.org/10.1124/dmd.114.057893

  4. Tracy, Timothy S.

    1. Altered CYP2C9 Activity Following Modulation of CYP3A4 Levels in Human Hepatocytes: an Example of Protein-Protein Interactions
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan and Timothy S. Tracy
      Drug Metabolism and Disposition November 2014, 42 (11) 1940-1946; DOI: https://doi.org/10.1124/dmd.114.057901

  5. Tweedie, Donald J.

    1. Altered CYP2C9 Activity Following Modulation of CYP3A4 Levels in Human Hepatocytes: an Example of Protein-Protein Interactions
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan and Timothy S. Tracy
      Drug Metabolism and Disposition November 2014, 42 (11) 1940-1946; DOI: https://doi.org/10.1124/dmd.114.057901

  6. Tyndale, Rachel F.

    1. Gene Variants in CYP2C19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes
      Andy Z. X. Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S. Ahluwalia, Neal L. Benowitz and Rachel F. Tyndale
      Drug Metabolism and Disposition November 2014, 42 (11) 1971-1977; DOI: https://doi.org/10.1124/dmd.114.060285

W

  1. Wakayama, Naomi

    1. In Silico Prediction of Major Drug Clearance Pathways by Support Vector Machines with Feature-Selected Descriptors
      Kouta Toshimoto, Naomi Wakayama, Makiko Kusama, Kazuya Maeda, Yuichi Sugiyama and Yutaka Akiyama
      Drug Metabolism and Disposition November 2014, 42 (11) 1811-1819; DOI: https://doi.org/10.1124/dmd.114.057893

  2. Wang, Li

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  3. Wang, Wei-Peng

    1. Rapid Production of Novel Pre-MicroRNA Agent hsa-mir-27b in Escherichia coli Using Recombinant RNA Technology for Functional Studies in Mammalian Cells
      Mei-Mei Li, Wei-Peng Wang, Wen-Juan Wu, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition November 2014, 42 (11) 1791-1795; DOI: https://doi.org/10.1124/dmd.114.060145

  4. Wang, Xianqin

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  5. Ward, Monika A.

    1. UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst
      Abby C. Collier, Yasuhiro Yamauchi, Brittany L.M. Sato, Luc R.A. Rougée and Monika A. Ward
      Drug Metabolism and Disposition November 2014, 42 (11) 1921-1925; DOI: https://doi.org/10.1124/dmd.114.059766

  6. Wienkers, Larry C.

    1. Evaluation of Near Infrared Fluorescent Labeling of Monoclonal Antibodies as a Tool for Tissue Distribution
      Kip P. Conner, Brooke M. Rock, Gayle K. Kwon, Joseph P. Balthasar, Lubna Abuqayyas, Larry C. Wienkers and Dan A. Rock
      Drug Metabolism and Disposition November 2014, 42 (11) 1906-1913; DOI: https://doi.org/10.1124/dmd.114.060319

  7. Wroblewski, Victor J.

    1. Application of FcRn Binding Assays to Guide mAb Development
      Amita Datta-Mannan and Victor J. Wroblewski
      Drug Metabolism and Disposition November 2014, 42 (11) 1867-1872; DOI: https://doi.org/10.1124/dmd.114.059089

  8. Wu, Wen-Juan

    1. Rapid Production of Novel Pre-MicroRNA Agent hsa-mir-27b in Escherichia coli Using Recombinant RNA Technology for Functional Studies in Mammalian Cells
      Mei-Mei Li, Wei-Peng Wang, Wen-Juan Wu, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition November 2014, 42 (11) 1791-1795; DOI: https://doi.org/10.1124/dmd.114.060145

X

  1. Xia, Mengmin

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

Y

  1. Yamauchi, Yasuhiro

    1. UDP-Glucuronosyltransferase 1a Enzymes Are Present and Active in the Mouse Blastocyst
      Abby C. Collier, Yasuhiro Yamauchi, Brittany L.M. Sato, Luc R.A. Rougée and Monika A. Ward
      Drug Metabolism and Disposition November 2014, 42 (11) 1921-1925; DOI: https://doi.org/10.1124/dmd.114.059766

  2. Yu, Ai-Ming

    1. Rapid Production of Novel Pre-MicroRNA Agent hsa-mir-27b in Escherichia coli Using Recombinant RNA Technology for Functional Studies in Mammalian Cells
      Mei-Mei Li, Wei-Peng Wang, Wen-Juan Wu, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition November 2014, 42 (11) 1791-1795; DOI: https://doi.org/10.1124/dmd.114.060145

  3. Yue, Wei

    1. Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation
      John Powell, Taleah Farasyn, Kathleen Köck, Xiaojie Meng, Sonia Pahwa, Kim L. R. Brouwer and Wei Yue
      Drug Metabolism and Disposition November 2014, 42 (11) 1964-1970; DOI: https://doi.org/10.1124/dmd.114.056945

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. Clinical CYP3A Inhibitor Alternatives to Ketoconazole, Clarithromycin and Itraconazole, Are Not Transported into the Liver by Hepatic Organic Anion Transporting Polypeptides and Organic Cation Transporter 1
      J. William Higgins, Alice B. Ke and Maciej J. Zamek-Gliszczynski
      Drug Metabolism and Disposition November 2014, 42 (11) 1780-1784; DOI: https://doi.org/10.1124/dmd.114.058784

  2. Zhan, Yunyun

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  3. Zhang, Ming

    1. Toward Sensitive and Accurate Analysis of Antibody Biotherapeutics by Liquid Chromatography Coupled with Mass Spectrometry
      Bo An, Ming Zhang and Jun Qu
      Drug Metabolism and Disposition November 2014, 42 (11) 1858-1866; DOI: https://doi.org/10.1124/dmd.114.058917

  4. Zhang, Youting

    1. Effects of Cytochrome P450 2C9 Polymorphism on Bosentan Metabolism
      Mengchun Chen, Youting Zhang, Peipei Pan, Li Wang, Yunyun Zhan, Hui Jin, Mengmin Xia, Xianqin Wang, Dapeng Dai, Jianping Cai and Guoxin Hu
      Drug Metabolism and Disposition November 2014, 42 (11) 1820-1825; DOI: https://doi.org/10.1124/dmd.114.060244

  5. Zhao, Baiteng

    1. Absorption, Distribution, Metabolism, and Excretion Considerations for the Development of Antibody-Drug Conjugates
      Tae H. Han and Baiteng Zhao
      Drug Metabolism and Disposition November 2014, 42 (11) 1914-1920; DOI: https://doi.org/10.1124/dmd.114.058586

  6. Zhou, Fanfan

    1. Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors
      Rosie A. Johnston, Tristan Rawling, Ting Chan, Fanfan Zhou and Michael Murray
      Drug Metabolism and Disposition November 2014, 42 (11) 1851-1857; DOI: https://doi.org/10.1124/dmd.114.059097

  7. Zhou, Qian

    1. Gene Variants in CYP2C19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes
      Andy Z. X. Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S. Ahluwalia, Neal L. Benowitz and Rachel F. Tyndale
      Drug Metabolism and Disposition November 2014, 42 (11) 1971-1977; DOI: https://doi.org/10.1124/dmd.114.060285

  8. Zhu, Andy Z. X.

    1. Gene Variants in CYP2C19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes
      Andy Z. X. Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S. Ahluwalia, Neal L. Benowitz and Rachel F. Tyndale
      Drug Metabolism and Disposition November 2014, 42 (11) 1971-1977; DOI: https://doi.org/10.1124/dmd.114.060285
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