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Clinical CYP3A Inhibitor Alternatives to Ketoconazole, Clarithromycin and Itraconazole, Are Not Transported into the Liver by Hepatic Organic Anion Transporting Polypeptides and Organic Cation Transporter 1

J. William Higgins, Alice B. Ke and Maciej J. Zamek-Gliszczynski
Drug Metabolism and Disposition November 2014, 42 (11) 1780-1784; DOI: https://doi.org/10.1124/dmd.114.058784

Article Information

vol. 42 no. 11 1780-1784
DOI 
https://doi.org/10.1124/dmd.114.058784
PubMed 
25106415
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 26, 2014
  • Accepted August 8, 2014
  • Published online September 24, 2014.

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Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. J. William Higgins,
  2. Alice B. Ke1, and
  3. Maciej J. Zamek-Gliszczynski2
  1. Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana
  1. Address correspondence to:
    Dr. Maciej J. Zamek-Gliszczynski, GlaxoSmithKline, 5 Moore Drive, RTP, NC 27709. E-mail: maciej.x.zamek-gliszczynski{at}gsk.com
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CYP3A Inhibitors Are Not Transported by OATP or OCT

J. William Higgins, Alice B. Ke and Maciej J. Zamek-Gliszczynski
Drug Metabolism and Disposition November 1, 2014, 42 (11) 1780-1784; DOI: https://doi.org/10.1124/dmd.114.058784
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