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Research ArticleArticle

CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers

Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
Drug Metabolism and Disposition November 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194
Yanhui Lu
Department of Pharmacology and Molecular Sciences (Y.L., C.W.H., N.N.B.), and Division of Clinical Pharmacology, Department of Medicine (E.J.F., C.W.H.), Johns Hopkins University School of Medicine, Baltimore, Maryland
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Edward J. Fuchs
Department of Pharmacology and Molecular Sciences (Y.L., C.W.H., N.N.B.), and Division of Clinical Pharmacology, Department of Medicine (E.J.F., C.W.H.), Johns Hopkins University School of Medicine, Baltimore, Maryland
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Craig W. Hendrix
Department of Pharmacology and Molecular Sciences (Y.L., C.W.H., N.N.B.), and Division of Clinical Pharmacology, Department of Medicine (E.J.F., C.W.H.), Johns Hopkins University School of Medicine, Baltimore, Maryland
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Namandjé N. Bumpus
Department of Pharmacology and Molecular Sciences (Y.L., C.W.H., N.N.B.), and Division of Clinical Pharmacology, Department of Medicine (E.J.F., C.W.H.), Johns Hopkins University School of Medicine, Baltimore, Maryland
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Article Information

vol. 42 no. 11 1796-1802
DOI 
https://doi.org/10.1124/dmd.114.060194
PubMed 
25117426

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 24, 2014
  • Accepted August 12, 2014
  • Published online September 24, 2014.

Article Versions

  • Earlier version (August 12, 2014 - 08:04).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yanhui Lu,
  2. Edward J. Fuchs,
  3. Craig W. Hendrix, and
  4. Namandjé N. Bumpus
  1. Department of Pharmacology and Molecular Sciences (Y.L., C.W.H., N.N.B.), and Division of Clinical Pharmacology, Department of Medicine (E.J.F., C.W.H.), Johns Hopkins University School of Medicine, Baltimore, Maryland
  1. Address correspondence to:
    Dr. Namandjé N. Bumpus, Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 N. Wolfe St., WBSB 302, Baltimore, MD 21205. E-mail: nbumpus1{at}jhmi.edu
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Drug Metabolism and Disposition: 42 (11)
Drug Metabolism and Disposition
Vol. 42, Issue 11
1 Nov 2014
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Research ArticleArticle

CYP3A5 Genotype Impacts Maraviroc Pharmacokinetics

Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
Drug Metabolism and Disposition November 1, 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194

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Research ArticleArticle

CYP3A5 Genotype Impacts Maraviroc Pharmacokinetics

Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
Drug Metabolism and Disposition November 1, 2014, 42 (11) 1796-1802; DOI: https://doi.org/10.1124/dmd.114.060194
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