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Research ArticleArticle

In Vitro Assay of Six UDP-Glucuronosyltransferase Isoforms in Human Liver Microsomes, Using Cocktails of Probe Substrates and Liquid Chromatography–Tandem Mass Spectrometry

Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
Drug Metabolism and Disposition November 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818
Kyung-Ah Seo
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Hyo-Ji Kim
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Eun Sook Jeong
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Nagi Abdalla
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Chang-Soo Choi
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Dong-Hyun Kim
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Jae-Gook Shin
Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
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Article Information

vol. 42 no. 11 1803-1810
DOI 
https://doi.org/10.1124/dmd.114.058818
PubMed 
25122565

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 8, 2014
  • Accepted August 13, 2014
  • Published online September 24, 2014.

Article Versions

  • Earlier version (August 13, 2014 - 08:29).
  • Earlier version (August 14, 2014 - 06:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kyung-Ah Seo,
  2. Hyo-Ji Kim,
  3. Eun Sook Jeong,
  4. Nagi Abdalla,
  5. Chang-Soo Choi,
  6. Dong-Hyun Kim, and
  7. Jae-Gook Shin
  1. Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Korea (K.-A.S., H.-J.K., E.S.J., N.A., D.-H.K., J.-G.S.); and Department of General Surgery, Inje University Busan Paik Hospital, Busan, Korea (C.-S.C.)
  1. Address correspondence to:
    Dr. Jae-Gook Shin or Dr. Dong-Hyun Kim, Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, 633-165 Gaegum-Dong, Busanjin-Gu, Busan 614-735, Korea. E-mail: phshinjg{at}inje.ac.kr or dhkim{at}inje.ac.kr
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Drug Metabolism and Disposition: 42 (11)
Drug Metabolism and Disposition
Vol. 42, Issue 11
1 Nov 2014
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Research ArticleArticle

In Vitro Cocktail Analysis for the Inhibition of Six UGTs

Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
Drug Metabolism and Disposition November 1, 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818

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Research ArticleArticle

In Vitro Cocktail Analysis for the Inhibition of Six UGTs

Kyung-Ah Seo, Hyo-Ji Kim, Eun Sook Jeong, Nagi Abdalla, Chang-Soo Choi, Dong-Hyun Kim and Jae-Gook Shin
Drug Metabolism and Disposition November 1, 2014, 42 (11) 1803-1810; DOI: https://doi.org/10.1124/dmd.114.058818
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