Department of Computer Science, Graduate School of Information Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan (K.T., Y.A.); Drug Metabolism and Pharmacokinetics Japan, Biopharmaceutical Assessment Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Ibaraki, Japan (N.W.); Laboratory of Pharmaceutical Regulatory Science (M.K.) and Laboratory of Molecular Pharmacokinetics (K.M.), Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan; and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)

Department of Computer Science, Graduate School of Information Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan (K.T., Y.A.); Drug Metabolism and Pharmacokinetics Japan, Biopharmaceutical Assessment Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Ibaraki, Japan (N.W.); Laboratory of Pharmaceutical Regulatory Science (M.K.) and Laboratory of Molecular Pharmacokinetics (K.M.), Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan; and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)

Department of Computer Science, Graduate School of Information Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan (K.T., Y.A.); Drug Metabolism and Pharmacokinetics Japan, Biopharmaceutical Assessment Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Ibaraki, Japan (N.W.); Laboratory of Pharmaceutical Regulatory Science (M.K.) and Laboratory of Molecular Pharmacokinetics (K.M.), Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan; and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)

Department of Computer Science, Graduate School of Information Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan (K.T., Y.A.); Drug Metabolism and Pharmacokinetics Japan, Biopharmaceutical Assessment Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Ibaraki, Japan (N.W.); Laboratory of Pharmaceutical Regulatory Science (M.K.) and Laboratory of Molecular Pharmacokinetics (K.M.), Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan; and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)

Department of Computer Science, Graduate School of Information Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan (K.T., Y.A.); Drug Metabolism and Pharmacokinetics Japan, Biopharmaceutical Assessment Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Ibaraki, Japan (N.W.); Laboratory of Pharmaceutical Regulatory Science (M.K.) and Laboratory of Molecular Pharmacokinetics (K.M.), Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan; and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)

Department of Computer Science, Graduate School of Information Science and Engineering, Tokyo Institute of Technology, Tokyo, Japan (K.T., Y.A.); Drug Metabolism and Pharmacokinetics Japan, Biopharmaceutical Assessment Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Ibaraki, Japan (N.W.); Laboratory of Pharmaceutical Regulatory Science (M.K.) and Laboratory of Molecular Pharmacokinetics (K.M.), Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan; and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)