Advertisement
Research ArticleArticle

Altered CYP2C9 Activity Following Modulation of CYP3A4 Levels in Human Hepatocytes: an Example of Protein-Protein Interactions

Diane Ramsden, Donald J. Tweedie, Tom S. Chan and Timothy S. Tracy
Drug Metabolism and Disposition November 2014, 42 (11) 1940-1946; DOI: https://doi.org/10.1124/dmd.114.057901

Article Information

vol. 42 no. 11 1940-1946
DOI 
https://doi.org/10.1124/dmd.114.057901
PubMed 
25157098
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 28, 2014
  • Accepted August 25, 2014
  • Published online October 1, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Diane Ramsden,
  2. Donald J. Tweedie,
  3. Tom S. Chan, and
  4. Timothy S. Tracy
  1. Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut (D.R., D.J.T., T.S.C.); and Department of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky (T.S.T.)
  1. Address correspondence to:
    Diane Ramsden, Drug Metabolism and Pharmacokinetics, Research and Development, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Road, Ridgefield, CT 06877. E-mail: diane.ramsden{at}boehringer-ingelheim.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to October 2024

AbstractFullPdf
Aug 20171148
Sep 2017597
Oct 20171126
Nov 20171274
Dec 20170114
Jan 20181185
Feb 20184108
Mar 20180122
Apr 20180164
May 20181163
Jun 20180182
Jul 20180225
Aug 20180134
Sep 20180156
Oct 20180217
Nov 20184494
Dec 20180777
Jan 20191622
Feb 20193537
Mar 201923114
Apr 201941614
May 2019078
Jun 20191310
Jul 2019075
Aug 20191168
Oct 20192810
Nov 20191520
Dec 20198179
Jan 2020112223
Feb 20200153
Mar 20203197
May 20201166
Jun 20201101
Jul 20203106
Aug 2020222
Sep 2020101812
Oct 20204462
Nov 20202064
Dec 20202110
Jan 20212298
Feb 20212252
Mar 20211461
Apr 2021810
May 20213032
Jun 20212040
Jul 20211533
Aug 20212423
Sep 20213262
Oct 20211131
Nov 20212410
Dec 20211011
Jan 20221741
Feb 20221721
Mar 20221920
Apr 20221561
May 20222520
Jun 20222464
Jul 202226610
Aug 20221522
Sep 2022831
Oct 20221441
Nov 20221721
Dec 20221066
Jan 20232172
Feb 2023952
Mar 20231431
Apr 20231437
May 20232166
Jun 20231110
Jul 20232735
Aug 2023644
Sep 202316516
Oct 20232236
Nov 20231835
Dec 202337105
Jan 20242275
Feb 20241030
Mar 20245282
Apr 20246653
May 20242942
Jun 20243869
Jul 20242790
Aug 20243012
Sep 20244454
Oct 20241760

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

CYP3A4 Levels Impact CYP2C9 Activity in Hepatocytes

Diane Ramsden, Donald J. Tweedie, Tom S. Chan and Timothy S. Tracy
Drug Metabolism and Disposition November 1, 2014, 42 (11) 1940-1946; DOI: https://doi.org/10.1124/dmd.114.057901
Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement