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Research ArticleArticle

Differential Expression of Drug Uptake and Efflux Transporters in Japanese Patients with Hepatocellular Carcinoma

Tadashi Namisaki, Elke Schaeffeler, Hiroshi Fukui, Hitoshi Yoshiji, Yoshiyuki Nakajima, Peter Fritz, Matthias Schwab and Anne T. Nies
Drug Metabolism and Disposition December 2014, 42 (12) 2033-2040; DOI: https://doi.org/10.1124/dmd.114.059832
Tadashi Namisaki
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Elke Schaeffeler
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Hiroshi Fukui
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Hitoshi Yoshiji
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Yoshiyuki Nakajima
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Peter Fritz
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Matthias Schwab
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Anne T. Nies
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
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Article Information

vol. 42 no. 12 2033-2040
DOI 
https://doi.org/10.1124/dmd.114.059832
PubMed 
25231932

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 9, 2014
  • Accepted September 17, 2014
  • Published online October 31, 2014.

Article Versions

  • Earlier version (September 17, 2014 - 11:34).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Tadashi Namisaki,
  2. Elke Schaeffeler,
  3. Hiroshi Fukui,
  4. Hitoshi Yoshiji,
  5. Yoshiyuki Nakajima,
  6. Peter Fritz,
  7. Matthias Schwab, and
  8. Anne T. Nies
  1. Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (T.N., E.S., P.F., M.S., A.T.N.); Third Department of Internal Medicine (T.N., H.F., H.Y.) and Department of Surgery (Y.N.), Nara Medical University, Kashihara, Japan; and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tübingen, Germany (M.S.)
  1. Address correspondence to:
    Dr. Anne T. Nies, Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Auerbachstrasse 112, D-70376 Stuttgart, Germany. E-mail: anne.nies{at}ikp-stuttgart.de
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Drug Metabolism and Disposition: 42 (12)
Drug Metabolism and Disposition
Vol. 42, Issue 12
1 Dec 2014
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Research ArticleArticle

Expression of Drug Uptake and Efflux Transporters in HCC

Tadashi Namisaki, Elke Schaeffeler, Hiroshi Fukui, Hitoshi Yoshiji, Yoshiyuki Nakajima, Peter Fritz, Matthias Schwab and Anne T. Nies
Drug Metabolism and Disposition December 1, 2014, 42 (12) 2033-2040; DOI: https://doi.org/10.1124/dmd.114.059832

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Research ArticleArticle

Expression of Drug Uptake and Efflux Transporters in HCC

Tadashi Namisaki, Elke Schaeffeler, Hiroshi Fukui, Hitoshi Yoshiji, Yoshiyuki Nakajima, Peter Fritz, Matthias Schwab and Anne T. Nies
Drug Metabolism and Disposition December 1, 2014, 42 (12) 2033-2040; DOI: https://doi.org/10.1124/dmd.114.059832
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