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Index by author

March 01, 2014; Volume 42,Issue 3

A

  1. Afzelius, Lovisa

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155
    2. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676
    3. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    4. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

  2. Andersson, Tommy B.

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155
    2. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676
    3. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    4. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

  3. Argikar, Aneesh A.

    1. Herb–Drug Interactions: Challenges and Opportunities for Improved Predictions
      Scott J. Brantley, Aneesh A. Argikar, Yvonne S. Lin, Swati Nagar and Mary F. Paine
      Drug Metabolism and Disposition March 2014, 42 (3) 301-317; DOI: https://doi.org/10.1124/dmd.113.055236

B

  1. Baryza, Jeremy

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  2. Beuvink, Iwan

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  3. Beverly, Mike

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  4. Bhutani, Priyadeep

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  5. Boos, Julien

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  6. Bowman, Keith

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  7. Boyle, Gary W.

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  8. Brantley, Scott J.

    1. Herb–Drug Interactions: Challenges and Opportunities for Improved Predictions
      Scott J. Brantley, Aneesh A. Argikar, Yvonne S. Lin, Swati Nagar and Mary F. Paine
      Drug Metabolism and Disposition March 2014, 42 (3) 301-317; DOI: https://doi.org/10.1124/dmd.113.055236

  9. Briem, Sveinn

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155

  10. Busacca, Carl A.

    1. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863

  11. Butcher, Neville J.

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  12. Bylund, Johan

    1. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676

C

  1. Cameron, Michael D.

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  2. Castanedo, Georgette

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  3. Chan, Tom S.

    1. Bridging In Vitro and In Vivo Metabolism and Transport of Faldaprevir in Human Using a Novel Cocultured Human Hepatocyte System, HepatoPac
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan, Mitchell E. Taub and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 394-406; DOI: https://doi.org/10.1124/dmd.113.055897

  4. Chen, Jacob Z

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  5. Chen, Lin-Zhi

    1. Generating an In Vitro–In Vivo Correlation for Metabolism and Liver Enrichment of a Hepatitis C Virus Drug, Faldaprevir, Using a Rat Hepatocyte Model (HepatoPac)
      Diane Ramsden, Donald J. Tweedie, Roger St. George, Lin-Zhi Chen and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 407-414; DOI: https://doi.org/10.1124/dmd.113.055947

  6. Cherala, Ganesh

    1. An Ethinyl Estradiol-Levonorgestrel Containing Oral Contraceptive Does Not Alter Cytochrome P4502C9 In Vivo Activity
      Ganesh Cherala, Jacob Pearson, Cheryl Maslen and Alison Edelman
      Drug Metabolism and Disposition March 2014, 42 (3) 323-325; DOI: https://doi.org/10.1124/dmd.113.054346
    2. Lack of In Vitro–In Vivo Correlation of Adulthood Cytochrome P450 Activities in Low-Birth-Weight Rats
      Ganesh Cherala, Jacob Pearson, Barent DuBois and Tahir Mahmood
      Drug Metabolism and Disposition March 2014, 42 (3) 481; DOI: https://doi.org/10.1124/dmd.113.056721

  7. Christensen, Jesper

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

D

  1. Dave, Mehul

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  2. Deng, Zhou J.

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  3. DuBois, Barent

    1. Lack of In Vitro–In Vivo Correlation of Adulthood Cytochrome P450 Activities in Low-Birth-Weight Rats
      Ganesh Cherala, Jacob Pearson, Barent DuBois and Tahir Mahmood
      Drug Metabolism and Disposition March 2014, 42 (3) 481; DOI: https://doi.org/10.1124/dmd.113.056721

  4. Duniec-Dmuchowski, Zofia

    1. Expression of the Orphan Cytosolic Sulfotransferase SULT1C3 in Human Intestine: Characterization of the Transcript Variant and Implications for Function
      Zofia Duniec-Dmuchowski, Elizabeth A. Rondini, Zachary E. Tibbs, Charles N. Falany, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 352-360; DOI: https://doi.org/10.1124/dmd.113.055665

E

  1. Edelman, Alison

    1. An Ethinyl Estradiol-Levonorgestrel Containing Oral Contraceptive Does Not Alter Cytochrome P4502C9 In Vivo Activity
      Ganesh Cherala, Jacob Pearson, Cheryl Maslen and Alison Edelman
      Drug Metabolism and Disposition March 2014, 42 (3) 323-325; DOI: https://doi.org/10.1124/dmd.113.054346

  2. Ellens, Harma

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  3. Englund, Gunilla

    1. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    2. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

F

  1. Fagerholm, Urban

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155

  2. Falany, Charles N.

    1. Expression of the Orphan Cytosolic Sulfotransferase SULT1C3 in Human Intestine: Characterization of the Transcript Variant and Implications for Function
      Zofia Duniec-Dmuchowski, Elizabeth A. Rondini, Zachary E. Tibbs, Charles N. Falany, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 352-360; DOI: https://doi.org/10.1124/dmd.113.055665

  3. Faller, Thomas

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  4. Fang, Hailin

    1. Regulation of Human Cytosolic Sulfotransferases 1C2 and 1C3 by Nuclear Signaling Pathways in LS180 Colorectal Adenocarcinoma Cells
      Elizabeth A. Rondini, Hailin Fang, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 361-368; DOI: https://doi.org/10.1124/dmd.113.055673

  5. Floby, Eva

    1. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676

G

  1. Garzel, Brandy

    1. The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
      Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E. Polli and Hongbing Wang
      Drug Metabolism and Disposition March 2014, 42 (3) 318-322; DOI: https://doi.org/10.1124/dmd.113.054189

  2. Ghosh, Kaushik

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  3. Gonnella, Nina

    1. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863

  4. Greenhill, Robert W.

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

H

  1. Heudi, Olivier

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  2. Heyward, Scott

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  3. Honda, Tomohiro

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

  4. Hoogstraate, Janet

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155
    2. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676
    3. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    4. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

  5. Hop, Cornelis E. C. A.

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  6. Huang, Shiew-Mei

    1. The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
      Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E. Polli and Hongbing Wang
      Drug Metabolism and Disposition March 2014, 42 (3) 318-322; DOI: https://doi.org/10.1124/dmd.113.054189

  7. Hunziker, Jürg

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

I

  1. Ito, Takashi

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

  2. Izumi, Takashi

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

J

  1. Jeso, Valer

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  2. Jia, Wei

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  3. Jia, Zhongfan

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  4. Johansson, Jenny

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155
    2. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676
    3. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    4. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

K

  1. Kallipatti, Sanjith

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  2. Kaneno-Urasaki, Yoko

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

  3. Khojasteh, S. Cyrus

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  4. Kimura, Takako

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

  5. Kocarek, Thomas A.

    1. Regulation of Human Cytosolic Sulfotransferases 1C2 and 1C3 by Nuclear Signaling Pathways in LS180 Colorectal Adenocarcinoma Cells
      Elizabeth A. Rondini, Hailin Fang, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 361-368; DOI: https://doi.org/10.1124/dmd.113.055673
    2. Expression of the Orphan Cytosolic Sulfotransferase SULT1C3 in Human Intestine: Characterization of the Transcript Variant and Implications for Function
      Zofia Duniec-Dmuchowski, Elizabeth A. Rondini, Zachary E. Tibbs, Charles N. Falany, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 352-360; DOI: https://doi.org/10.1124/dmd.113.055665

  6. Krauser, Joel

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  7. Krishnamurthy, Prasad

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

L

  1. Li, Xiaohai

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  2. Li, Yongmei

    1. Generating an In Vitro–In Vivo Correlation for Metabolism and Liver Enrichment of a Hepatitis C Virus Drug, Faldaprevir, Using a Rat Hepatocyte Model (HepatoPac)
      Diane Ramsden, Donald J. Tweedie, Roger St. George, Lin-Zhi Chen and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 407-414; DOI: https://doi.org/10.1124/dmd.113.055947
    2. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863
    3. Bridging In Vitro and In Vivo Metabolism and Transport of Faldaprevir in Human Using a Novel Cocultured Human Hepatocyte System, HepatoPac
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan, Mitchell E. Taub and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 394-406; DOI: https://doi.org/10.1124/dmd.113.055897

  3. Lin, Yvonne S.

    1. Herb–Drug Interactions: Challenges and Opportunities for Improved Predictions
      Scott J. Brantley, Aneesh A. Argikar, Yvonne S. Lin, Swati Nagar and Mary F. Paine
      Drug Metabolism and Disposition March 2014, 42 (3) 301-317; DOI: https://doi.org/10.1124/dmd.113.055236

  4. Litherland, Karine

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  5. Liu, Lichuan

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  6. Lööf, Johan

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155
    2. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676
    3. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

  7. Lundquist, Patrik

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155
    2. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676
    3. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    4. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

  8. Ly, Justin

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  9. Lyssikatos, Joseph

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

M

  1. Ma, Shuguang

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  2. Magee, Mindy H.

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  3. Mahmood, Tahir

    1. Lack of In Vitro–In Vivo Correlation of Adulthood Cytochrome P450 Activities in Low-Birth-Weight Rats
      Ganesh Cherala, Jacob Pearson, Barent DuBois and Tahir Mahmood
      Drug Metabolism and Disposition March 2014, 42 (3) 481; DOI: https://doi.org/10.1124/dmd.113.056721

  4. Mandlekar, Sandhya

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  5. Martin, Darren J.

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  6. Maslen, Cheryl

    1. An Ethinyl Estradiol-Levonorgestrel Containing Oral Contraceptive Does Not Alter Cytochrome P4502C9 In Vivo Activity
      Ganesh Cherala, Jacob Pearson, Cheryl Maslen and Alison Edelman
      Drug Metabolism and Disposition March 2014, 42 (3) 323-325; DOI: https://doi.org/10.1124/dmd.113.054346

  7. Matsushima, Nobuko

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

  8. Messick, Kirsten

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  9. Micalizio, Glenn C.

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  10. Minchin, Rodney F.

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  11. Monteiro, Michael J.

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  12. Mortimer, Gysell M.

    1. Interaction of Human Arylamine N-Acetyltransferase 1 with Different Nanomaterials
      Zhou J. Deng, Neville J. Butcher, Gysell M. Mortimer, Zhongfan Jia, Michael J. Monteiro, Darren J. Martin and Rodney F. Minchin
      Drug Metabolism and Disposition March 2014, 42 (3) 377-383; DOI: https://doi.org/10.1124/dmd.113.055988

  13. Mulder, Teresa

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

N

  1. Nagar, Swati

    1. Herb–Drug Interactions: Challenges and Opportunities for Improved Predictions
      Scott J. Brantley, Aneesh A. Argikar, Yvonne S. Lin, Swati Nagar and Mary F. Paine
      Drug Metabolism and Disposition March 2014, 42 (3) 301-317; DOI: https://doi.org/10.1124/dmd.113.055236

  2. Nash, Mike

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  3. Natt, François

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

O

  1. O'Brien, Drané

    1. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863

  2. Okabe, Hiromi

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

P

  1. Paine, Mary F.

    1. Herb–Drug Interactions: Challenges and Opportunities for Improved Predictions
      Scott J. Brantley, Aneesh A. Argikar, Yvonne S. Lin, Swati Nagar and Mary F. Paine
      Drug Metabolism and Disposition March 2014, 42 (3) 301-317; DOI: https://doi.org/10.1124/dmd.113.055236

  2. Pearson, Jacob

    1. An Ethinyl Estradiol-Levonorgestrel Containing Oral Contraceptive Does Not Alter Cytochrome P4502C9 In Vivo Activity
      Ganesh Cherala, Jacob Pearson, Cheryl Maslen and Alison Edelman
      Drug Metabolism and Disposition March 2014, 42 (3) 323-325; DOI: https://doi.org/10.1124/dmd.113.054346
    2. Lack of In Vitro–In Vivo Correlation of Adulthood Cytochrome P450 Activities in Low-Birth-Weight Rats
      Ganesh Cherala, Jacob Pearson, Barent DuBois and Tahir Mahmood
      Drug Metabolism and Disposition March 2014, 42 (3) 481; DOI: https://doi.org/10.1124/dmd.113.056721

  3. Polli, James E.

    1. The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
      Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E. Polli and Hongbing Wang
      Drug Metabolism and Disposition March 2014, 42 (3) 318-322; DOI: https://doi.org/10.1124/dmd.113.054189

  4. Projean, Denis

    1. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932

R

  1. Ramarao, Manjunath

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  2. Ramsden, Diane

    1. Generating an In Vitro–In Vivo Correlation for Metabolism and Liver Enrichment of a Hepatitis C Virus Drug, Faldaprevir, Using a Rat Hepatocyte Model (HepatoPac)
      Diane Ramsden, Donald J. Tweedie, Roger St. George, Lin-Zhi Chen and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 407-414; DOI: https://doi.org/10.1124/dmd.113.055947
    2. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863
    3. Bridging In Vitro and In Vivo Metabolism and Transport of Faldaprevir in Human Using a Novel Cocultured Human Hepatocyte System, HepatoPac
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan, Mitchell E. Taub and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 394-406; DOI: https://doi.org/10.1124/dmd.113.055897

  3. Roberts, Andrew D.

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  4. Rodrigues, A. David

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  5. Rondini, Elizabeth A.

    1. Regulation of Human Cytosolic Sulfotransferases 1C2 and 1C3 by Nuclear Signaling Pathways in LS180 Colorectal Adenocarcinoma Cells
      Elizabeth A. Rondini, Hailin Fang, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 361-368; DOI: https://doi.org/10.1124/dmd.113.055673
    2. Expression of the Orphan Cytosolic Sulfotransferase SULT1C3 in Human Intestine: Characterization of the Transcript Variant and Implications for Function
      Zofia Duniec-Dmuchowski, Elizabeth A. Rondini, Zachary E. Tibbs, Charles N. Falany, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 352-360; DOI: https://doi.org/10.1124/dmd.113.055665

  6. Runge-Morris, Melissa

    1. Regulation of Human Cytosolic Sulfotransferases 1C2 and 1C3 by Nuclear Signaling Pathways in LS180 Colorectal Adenocarcinoma Cells
      Elizabeth A. Rondini, Hailin Fang, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 361-368; DOI: https://doi.org/10.1124/dmd.113.055673
    2. Expression of the Orphan Cytosolic Sulfotransferase SULT1C3 in Human Intestine: Characterization of the Transcript Variant and Implications for Function
      Zofia Duniec-Dmuchowski, Elizabeth A. Rondini, Zachary E. Tibbs, Charles N. Falany, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 352-360; DOI: https://doi.org/10.1124/dmd.113.055665

S

  1. Selvakumar, Sindhuja

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  2. Selvam, Sabariya

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  3. Sharma, Raman

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  4. Sinz, Michael W.

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  5. Sjögren, Ingemo

    1. Prediction of In Vivo Rat Biliary Drug Clearance from an In Vitro Hepatocyte Efflux Model
      Patrik Lundquist, Johan Lööf, Urban Fagerholm, Ingemo Sjögren, Jenny Johansson, Sveinn Briem, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 459-468; DOI: https://doi.org/10.1124/dmd.113.054155

  6. Skogastierna, Cristine

    1. Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
      Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
      Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
    2. Functional ATP-Binding Cassette Drug Efflux Transporters in Isolated Human and Rat Hepatocytes Significantly Affect Assessment of Drug Disposition
      Patrik Lundquist, Gunilla Englund, Cristine Skogastierna, Johan Lööf, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 448-458; DOI: https://doi.org/10.1124/dmd.113.054528

  7. Sohlenius-Sternbeck, Anna-Karin

    1. The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions
      Patrik Lundquist, Johan Lööf, Anna-Karin Sohlenius-Sternbeck, Eva Floby, Jenny Johansson, Johan Bylund, Janet Hoogstraate, Lovisa Afzelius and Tommy B. Andersson
      Drug Metabolism and Disposition March 2014, 42 (3) 469-480; DOI: https://doi.org/10.1124/dmd.113.054676

  8. St. George, Roger

    1. Generating an In Vitro–In Vivo Correlation for Metabolism and Liver Enrichment of a Hepatitis C Virus Drug, Faldaprevir, Using a Rat Hepatocyte Model (HepatoPac)
      Diane Ramsden, Donald J. Tweedie, Roger St. George, Lin-Zhi Chen and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 407-414; DOI: https://doi.org/10.1124/dmd.113.055947

  9. Stoeckli, Markus

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  10. Subramanian, Murali

    1. Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
      Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
      Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491

  11. Swart, Piet

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

T

  1. Takahashi, Ryan

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

  2. Taub, Mitchell E.

    1. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863
    2. Bridging In Vitro and In Vivo Metabolism and Transport of Faldaprevir in Human Using a Novel Cocultured Human Hepatocyte System, HepatoPac
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan, Mitchell E. Taub and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 394-406; DOI: https://doi.org/10.1124/dmd.113.055897

  3. Taylor, Maxine A.

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  4. Tibbs, Zachary E.

    1. Expression of the Orphan Cytosolic Sulfotransferase SULT1C3 in Human Intestine: Characterization of the Transcript Variant and Implications for Function
      Zofia Duniec-Dmuchowski, Elizabeth A. Rondini, Zachary E. Tibbs, Charles N. Falany, Melissa Runge-Morris and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2014, 42 (3) 352-360; DOI: https://doi.org/10.1124/dmd.113.055665

  5. Tweedie, Donald J.

    1. Generating an In Vitro–In Vivo Correlation for Metabolism and Liver Enrichment of a Hepatitis C Virus Drug, Faldaprevir, Using a Rat Hepatocyte Model (HepatoPac)
      Diane Ramsden, Donald J. Tweedie, Roger St. George, Lin-Zhi Chen and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 407-414; DOI: https://doi.org/10.1124/dmd.113.055947
    2. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863
    3. Bridging In Vitro and In Vivo Metabolism and Transport of Faldaprevir in Human Using a Novel Cocultured Human Hepatocyte System, HepatoPac
      Diane Ramsden, Donald J. Tweedie, Tom S. Chan, Mitchell E. Taub and Yongmei Li
      Drug Metabolism and Disposition March 2014, 42 (3) 394-406; DOI: https://doi.org/10.1124/dmd.113.055897

V

  1. van de Kerkhof, Esther

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

  2. Vargeese, Chandra

    1. Biodistribution and Metabolism Studies of Lipid Nanoparticle–Formulated Internally [3H]-Labeled siRNA in Mice
      Jesper Christensen, Karine Litherland, Thomas Faller, Esther van de Kerkhof, François Natt, Jürg Hunziker, Julien Boos, Iwan Beuvink, Keith Bowman, Jeremy Baryza, Mike Beverly, Chandra Vargeese, Olivier Heudi, Markus Stoeckli, Joel Krauser and Piet Swart
      Drug Metabolism and Disposition March 2014, 42 (3) 431-440; DOI: https://doi.org/10.1124/dmd.113.055434

W

  1. Walker, Gregory S.

    1. Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
      Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
      Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726

  2. Wang, Hongbing

    1. The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
      Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E. Polli and Hongbing Wang
      Drug Metabolism and Disposition March 2014, 42 (3) 318-322; DOI: https://doi.org/10.1124/dmd.113.054189

  3. Wong, Harvey

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

X

  1. Xu, Jun

    1. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863

Y

  1. Yamasaki, Atsushi

    1. Alpha-Amylase Inhibitor, CS-1036 Binds to Serum Amylase in a Concentration-Dependent and Saturable Manner
      Tomohiro Honda, Yoko Kaneno-Urasaki, Takashi Ito, Takako Kimura, Nobuko Matsushima, Hiromi Okabe, Atsushi Yamasaki and Takashi Izumi
      Drug Metabolism and Disposition March 2014, 42 (3) 326-333; DOI: https://doi.org/10.1124/dmd.113.054452

  2. Yang, Hui

    1. The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
      Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E. Polli and Hongbing Wang
      Drug Metabolism and Disposition March 2014, 42 (3) 318-322; DOI: https://doi.org/10.1124/dmd.113.054189

  3. Young, Graeme C.

    1. Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans
      Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
      Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

  4. Yue, Qin

    1. Investigations into the Mechanisms of Pyridine Ring Cleavage in Vismodegib
      S. Cyrus Khojasteh, Qin Yue, Shuguang Ma, Georgette Castanedo, Jacob Z Chen, Joseph Lyssikatos, Teresa Mulder, Ryan Takahashi, Justin Ly, Kirsten Messick, Wei Jia, Lichuan Liu, Cornelis E. C. A. Hop and Harvey Wong
      Drug Metabolism and Disposition March 2014, 42 (3) 343-351; DOI: https://doi.org/10.1124/dmd.113.055715

Z

  1. Zhang, Lei

    1. The Role of Bile Salt Export Pump Gene Repression in Drug-Induced Cholestatic Liver Toxicity
      Brandy Garzel, Hui Yang, Lei Zhang, Shiew-Mei Huang, James E. Polli and Hongbing Wang
      Drug Metabolism and Disposition March 2014, 42 (3) 318-322; DOI: https://doi.org/10.1124/dmd.113.054189

  2. Zhou, Jin

    1. Enzyme-Transporter Interplay in the Formation and Clearance of Abundant Metabolites of Faldaprevir Found in Excreta but not in Circulation
      Yongmei Li, Jin Zhou, Diane Ramsden, Mitchell E. Taub, Drané O'Brien, Jun Xu, Carl A. Busacca, Nina Gonnella and Donald J. Tweedie
      Drug Metabolism and Disposition March 2014, 42 (3) 384-393; DOI: https://doi.org/10.1124/dmd.113.055863
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